Structural Heart最新文献

{"title":"Aims & Scope","authors":"","doi":"10.1016/S2474-8706(25)00281-7","DOIUrl":"10.1016/S2474-8706(25)00281-7","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 7","pages":"Article 100689"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT Imaging for Valvular Interventions","authors":"Dee Dee Wang MD ,&nbsp;Pedro A. Villablanca MD ,&nbsp;Kent Chak-Yu So MD ,&nbsp;Robert J. Cubeddu MD ,&nbsp;Brian P. O’Neill MD ,&nbsp;William W. O’Neill MD","doi":"10.1016/j.shj.2025.100667","DOIUrl":"10.1016/j.shj.2025.100667","url":null,"abstract":"<div><div>Physician-led computed tomography (CT) imaging for valvular interventions has directly contributed to the safety and scalability of transcatheter aortic valve interventions globally. As the shift of the global population’s valvular heart disease extends into the transcatheter aortic, mitral, pulmonic, and tricuspid space, CT imaging for valvular interventions in new anatomical pathophysiologies becomes more important than ever. Health systems dedicated to investing in physician-led structural heart imaging CT procedural planning expertise and transcatheter treatment advancements can bring life-saving innovative care to patients in need.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 7","pages":"Article 100667"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simulation for Procedural Planning and Intracardiac Echo for Enhancing Precision in Cardiac Interventions With a Focus on Left Atrial Appendage Closure","authors":"Jaya Chandrasekhar MBBS, MS, PhD ,&nbsp;Jacqueline Saw MD","doi":"10.1016/j.shj.2025.100671","DOIUrl":"10.1016/j.shj.2025.100671","url":null,"abstract":"<div><div>In recent years, structural interventions have explored three-dimensional printing and computer simulation technologies to facilitate optimal device selections for more efficient procedures with fewer patient complications. Cardiovascular procedures, both structural interventions and electrophysiological procedures, have examined the utility of intracardiac echocardiography. In this review, we will discuss the growth of these technologies and highlight recent studies with a key focus on left atrial appendage closure.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 7","pages":"Article 100671"},"PeriodicalIF":1.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reverse Remodeling Induced by Transcatheter Left Ventricular Restoration System Is Sustained Through 2 Years of Follow-Up","authors":"Alena Kurlianskaya MD, PhD ,&nbsp;Michael L. Chuang MD ,&nbsp;Oleg Polonetsky MD, PhD ,&nbsp;Olesya Shatova MD ,&nbsp;Jason R. Foerst MD ,&nbsp;Kendra J. Grubb MD, MHA ,&nbsp;Martin B. Leon MD ,&nbsp;Ulrich P. Jorde MD ,&nbsp;Mark Reisman MD ,&nbsp;Daniel Burkhoff MD, PhD ,&nbsp;AccuCinch Study Investigators","doi":"10.1016/j.shj.2025.100694","DOIUrl":"10.1016/j.shj.2025.100694","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 9","pages":"Article 100694"},"PeriodicalIF":2.8,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neo-Sinus Washout Time Following Transcatheter Aortic Valve Replacement and Hemodynamic Outcomes","authors":"Shivabalan Kathavarayan Ramu MD ,&nbsp;Toshiaki Isogai MD, MPH ,&nbsp;Saksham Beotra MS ,&nbsp;Vishwum Kapadia ,&nbsp;Nikita Thakore ,&nbsp;Ankit Agrawal MD ,&nbsp;Shashank Shekhar MD ,&nbsp;Maryam Muhammad Ali Majeed-Saidan MD ,&nbsp;Rohan Prasad MD ,&nbsp;Agam Bansal MD ,&nbsp;Abdelrahman Abushouk MD ,&nbsp;Odette Iskandar MD ,&nbsp;Larisa G. Tereshchenko MD, PhD ,&nbsp;Grant Reed MD ,&nbsp;Rishi Puri MD, PhD ,&nbsp;James Yun MD ,&nbsp;Serge Harb MD ,&nbsp;Rhonda Miyasaka MD ,&nbsp;Zoran Popovic MD ,&nbsp;Amar Krishnaswamy MD ,&nbsp;Samir R. Kapadia MD","doi":"10.1016/j.shj.2025.100686","DOIUrl":"10.1016/j.shj.2025.100686","url":null,"abstract":"<div><h3>Background</h3><div>Leaflet thrombosis and transcatheter heart valve dysfunction are key concerns following transcatheter aortic valve replacement (TAVR). Prolonged neo-sinus washout time (NWT) may predispose patients to hypoattenuated leaflet thickening (HALT) and leaflet thrombosis, increasing the risk of valve degeneration. This study evaluates the association between in vivo NWT derived from aortograms using computer vision and hemodynamic outcomes at 30 days and 1 year post-TAVR.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed 2254 patients (mean age: 79 ​± ​9 years, 40% female) who underwent TAVR with balloon-expandable valves between 2016 and 2020. Patients were tertile stratified into tertile 1 (T1) (1.444-1.870 ​s; n ​= ​752), T2 (1.870-1.939 ​s; n ​= ​752), and T3 (1.939-2.110 ​s; n ​= ​751) based on their NWTs.</div></div><div><h3>Results</h3><div>At 30 days, T3 had a higher transvalvular aortic valve mean gradient than T1 (12.61 ​± ​5.07 mmHg vs. 11.98 ​± ​4.75 mmHg, <em>p</em> ​= ​0.03). In multivariate modeling, T3 was significantly associated with increased aortic valve mean gradient compared to T1 (estimate: 0.703, <em>p</em> ​= ​0.02). NWT was higher in patients with HALT at 30 days (1.970 ​± ​0.047 ​s vs. 1.889 ​± ​0.100 ​s, <em>p</em> ​= ​0.001), with each 0.1 ​second increase in NWT tripling the odds of HALT.</div></div><div><h3>Conclusions</h3><div>Prolonged NWT is associated with higher transvalvular gradients and independently predicts HALT post-TAVR. NWT may serve as a novel marker to identify patients at risk of valve dysfunction and guide early pharmacotherapy.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 9","pages":"Article 100686"},"PeriodicalIF":2.8,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144865981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tricuspid Annulus Measurements in Severe Tricuspid Regurgitation: Comparative Analysis of Cardiac-Gated Computed Tomography Versus Three-Dimensional Transesophageal Echocardiography","authors":"Pranav Chandrashekar MD ,&nbsp;Anas Zaqut MD ,&nbsp;Raluca McCallum MD ,&nbsp;Chara Rydzak MD, PhD ,&nbsp;En-Ha Wu MD ,&nbsp;Firas Zahr MD ,&nbsp;Scott M. Chadderdon MD","doi":"10.1016/j.shj.2025.100679","DOIUrl":"10.1016/j.shj.2025.100679","url":null,"abstract":"<div><h3>Background</h3><div>Treatment options for severe tricuspid regurgitation (TR) require a multimodal analysis of the tricuspid annulus (TA). Cardiac computed tomography (CT) is currently considered the gold standard for annular perimeter measurements, though three-dimensional transesophageal echocardiography (3D TEE) can yield similar results. As such, we sought to determine the accuracy and precision of 3D TEE imaging of the TA perimeter compared to CT imaging in outpatients with severe TR.</div></div><div><h3>Methods</h3><div>Fifty-five patients were referred for multimodality workup for severe TR that included CT and 3D TEE. The 3D TEE imaging was performed in the mid-esophageal (ME) and transgastric views. A semiautomated software program was used to identify and measure the TA with additional manual optimization by the reader. These 3D TEE measurements were compared to cardiac CT imaging.</div></div><div><h3>Results</h3><div>Out of 55 patients, 3 were excluded for hiatal hernias and 1 was excluded for severe kidney disease. Fifty-one studied patients had an average age of 76 ± 10 years with 59% female. The 3D TEE analysis of the TA perimeter demonstrated an excellent correlation with CT from the ME view, R = 0.88, and from the TG view, R = 0.86, with an average difference of approximately 8.5% when compared to CT. TEE inter-reader variability was approximately 6%, whereas CT variability was 1.4%</div></div><div><h3>Conclusions</h3><div>The 3D TEE TA perimeter measurements are accurate when compared to CT with a variability of 8.5%. While CT remains more precise, 3D TEE imaging for TA sizing should be considered a near-equivalent modality to CT.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 10","pages":"Article 100679"},"PeriodicalIF":2.8,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Baseline Anteroposterior Mitral Annular Dimensions on Clinical Outcomes after MitraClip for Secondary Mitral Regurgitation","authors":"Jason H. Rogers MD ,&nbsp;Thomas W. Smith MD ,&nbsp;Jeroen J. Bax MD, PhD ,&nbsp;Federico M. Asch MD ,&nbsp;D. Scott Lim MD ,&nbsp;Ningyan Wong MBBS ,&nbsp;Janani Aiyer MS ,&nbsp;William T. Abraham MD ,&nbsp;JoAnn Lindenfeld MD ,&nbsp;Michael J. Mack MD ,&nbsp;Gregg W. Stone MD ,&nbsp;Steven F. Bolling MD","doi":"10.1016/j.shj.2025.100460","DOIUrl":"10.1016/j.shj.2025.100460","url":null,"abstract":"<div><h3>Background</h3><div>In the randomized Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT; <span><span>NCT01626079</span><svg><path></path></svg></span>) trial, mitral transcatheter edge-to-edge repair (M-TEER) improved clinical outcomes in patients with severe secondary mitral regurgitation (MR). A prior post hoc analysis from the COAPT trial showed that increasing anteroposterior mitral annular diameter (APMAD) was the sole independent echocardiographic predictor of the composite endpoint of death or heart failure hospitalizations (HFH) at 2 years. Given the relationship between the mitral annulus and leaflets, we examined the association of baseline APMAD with long-term clinical outcomes.</div></div><div><h3>Methods</h3><div>COAPT patients (n = 575) were stratified into tertiles by baseline APMAD as follows: small APMAD, medium APMAD, and large APMAD. APMAD was measured in the anteroposterior direction from the parasternal long-axis view at end-diastole and in the intercommissural direction from the apical two-chamber view.</div></div><div><h3>Results</h3><div>Patients with larger baseline APMAD were more often male and had fewer comorbidities, larger ventricles, and larger mitral orifice areas. At 2 years, there were no significant differences in MR severity and the composite endpoint of death or HFH in patients treated with M-TEER by baseline APMAD. In patients treated with guideline-directed medical therapy (GDMT) alone, there were no significant differences in MR severity, but the composite endpoint of death or HFH was higher in patients with the largest baseline APMADs. The treatment effect of M-TEER was consistent among APMAD tertiles (<em>p</em>_interaction = 0.87).</div></div><div><h3>Conclusions</h3><div>APMAD was a predictor of adverse outcomes in patients treated with GDMT alone. M-TEER reduced MR severity and the risk of death or HFH regardless of baseline APMAD compared with GDMT alone.</div></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 6","pages":"Article 100460"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144280961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"72261 | Development of a Mitral Valve Digital Twin for Transcatheter Edge-to-Edge Repair","authors":"Natalie Simonian ,&nbsp;Sneha Vakamudi ,&nbsp;Mark Pirwitz ,&nbsp;Michael Sacks","doi":"10.1016/j.shj.2025.100560","DOIUrl":"10.1016/j.shj.2025.100560","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 ","pages":"Article 100560"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144344638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"72337 | Prognostic Value of Baseline Aortic Valve Gradient in Acute Heart Failure Patients Undergoing TAVR","authors":"Karthik Vedantam ,&nbsp;Christian Torres ,&nbsp;Peter Eckman ,&nbsp;Martin Leon ,&nbsp;Nirat Beohar ,&nbsp;Sri Mandava","doi":"10.1016/j.shj.2025.100538","DOIUrl":"10.1016/j.shj.2025.100538","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 ","pages":"Article 100538"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"72155 | Impacts of Tricuspid Valve Leaflet Configuration on Outcomes of Surgical Repair Treatment","authors":"Mitsunobu Kitamura ,&nbsp;Kanako Kishiki ,&nbsp;Tomoyuki Yaguchi ,&nbsp;Yasunari Hayami ,&nbsp;Ryoto Inaba ,&nbsp;Shuro Narui ,&nbsp;Satonori Maekawara ,&nbsp;Kohei Sumi ,&nbsp;Yuki Izumi ,&nbsp;Itaru Takamisawa ,&nbsp;Yoko Furuichi ,&nbsp;Mamoru Nanasato ,&nbsp;Kenta Zaikokuji ,&nbsp;Tomoki Shimokawa ,&nbsp;Mitsuaki Isobe ,&nbsp;Tomohiro Iwakura","doi":"10.1016/j.shj.2025.100493","DOIUrl":"10.1016/j.shj.2025.100493","url":null,"abstract":"","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"9 ","pages":"Article 100493"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}