Medical Journal of Dr. D.Y. Patil University最新文献_第6页

Study of fine-needle aspiration cytology of breast lumps in rural area of Bastar district, Chhattisgarh 恰蒂斯加尔邦巴斯塔尔农村地区乳腺肿块细针穿刺细胞学研究

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_250_16

S. Badge, A. Ovhal, K. Azad, Avinash T Meshram

{"title":"Study of fine-needle aspiration cytology of breast lumps in rural area of Bastar district, Chhattisgarh","authors":"S. Badge, A. Ovhal, K. Azad, Avinash T Meshram","doi":"10.4103/MJDRDYPU.MJDRDYPU_250_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_250_16","url":null,"abstract":"Aims and Objectives: In India, breast cancer is the second most common cancer in women. The fine-needle aspiration cytology (FNAC) of breast lump is highly sensitive, easy to perform, and cost effective that can be carried out at outpatient department. The aim of this study is to identify the most common benign and malignant tumors of the breast lump on FNAC in our institute. Materials and Methods: The present study was carried out in the Pathology Department of our institute over 2 years from January 2014 to December 2015. Procedure is done using 24-gauge needle fitted on 10 ml disposable syringe in syringe holder. The wet smear fixed with ether-alcohol mixture stained with hematoxylin and eosin and papanicolaou stain. The air-dried smear stained with May-Grunwald Giemsa stain. Results: A total of 731 cases were obtained in the cytopathology section over 2 years from January 2014 to December 2015, out of which 220 (30.10%) cases were breast lump FNACs. Benign tumors contributed to 162 cases (73.64%) and malignant tumors to 58 cases (26.36%). Among benign tumor, fibroadenoma was the most common tumor which constituted 121 cases (55%). Infiltrating duct carcinoma was the most common malignant breast tumor in the present study comprising 53 cases (24.09%). Conclusion: The most common benign tumor in the present study was fibroadenoma and the most common malignant tumor was invasive ductal carcinoma.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"339"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42202459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Infection by multidrug-resistant Chryseobacterium indologenes in cases of obstructive uropathy: Case series with short review 多药耐药吲哚黄杆菌在梗阻性尿病中的感染:简短回顾的病例系列

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_201_16

M. Palewar, S. Mudshingkar, V. Dohe, R. Bharadwaj

{"title":"Infection by multidrug-resistant Chryseobacterium indologenes in cases of obstructive uropathy: Case series with short review","authors":"M. Palewar, S. Mudshingkar, V. Dohe, R. Bharadwaj","doi":"10.4103/MJDRDYPU.MJDRDYPU_201_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_201_16","url":null,"abstract":"Chryseobacterium spp. are Gram-negative, aerobic, nonfermentative, oxidase-positive and catalase-positive nonmotile bacilli that produce yellow to orange pigment. We report three cases of complicated urinary tract infections (UTIs) caused by Chryseobacterium indologenes in patients with obstructive uropathy. The first case was a known case of diabetes mellitus with right emphysematous pyelonephritis and obstructive uropathy due to prostate enlargement. The patient underwent dialysis for renal failure and subsequently developed UTI by multidrug-resistant C. indologenes. The second case was 72 years old known case of ischemic heart disease. He had acute retention of urine that was relieved after catheterization. He had obstructive uropathy due to transitional cell carcinoma of the bladder and had developed UTI due to C. indologenes. The third case was 38-year-old unmarried female admitted for difficulty in micturition and was catheterized for the same. Obstructive uropathy was due to two fibroids, first fibroid was 9.2 cm × 9.2 cm sized subserosal in the lower segment of the uterus on posterior wall (posterior cervical fibroid) and second fibroid was approximately 1.5 cm × 2.1 cm fundal fibroid; however, the patient developed UTI on the 7th day of catheterization due to C. indologenes. These cases were treated by relieving urinary obstruction and appropriate antibiotic treatment as per antibiotic susceptibility test results.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"376"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45340371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Spectrum of lymph node lesions as determined by histopathology 由组织病理学确定的淋巴结病变谱

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_296_16

Pradhan M. Pagaro, B. Banerjee, A. Khandelwal, Aditi Pandey, A. Gambhir

{"title":"Spectrum of lymph node lesions as determined by histopathology","authors":"Pradhan M. Pagaro, B. Banerjee, A. Khandelwal, Aditi Pandey, A. Gambhir","doi":"10.4103/MJDRDYPU.MJDRDYPU_296_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_296_16","url":null,"abstract":"Background and Objective: Lymph node lesions form a wide range of spectrum, exhibiting manifestations in both hematopoietic tissue and lympho reticular system. It is necessary to document the same spectrum in a particular region to understand the trend and diseases occurring frequently in that region. The range encompasses benign reactive changes to frank malignant lymphoma and metastatic deposits. Histopathology is considered to be the gold standard and its relevance to clinical diagnosis is studied here. Materials and Methods: A total of 200 cases were studied retrospectively in this study. Samples received were either biopsy or node resection specimens, and clinical history was recorded for each of them. Immunohistochemistry and special stains were performed as and when required. Results: Clinical diagnosis had a diagnostic accuracy of 71% approximately using histopathology as the gold standard. Most of the benign diseases were either reactive or tubercular lymphadenitis, whereas non-Hodgkin Follicular lymphoma had the maximum incidence among lymphomas. Conclusion: This study concluded that cervical group of superficial lymph nodes are most frequently encountered as palpable nodal swellings. The clinical suspicion of malignancy remains high in most of the cases due to the matted and enlarged presentation of lymph nodes. Histopathology revealed that only 33.5% of the cases to be malignant of which the most common was Follicular Lymphoma (non-Hodgkin type). The clinical accuracy of diagnosing malignant lesions thus coming to 71% approximately.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"343"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44312623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Vitamin D deficiency and its association with thyroid peroxidase antibodies positive hypothyroidism - Experience in a tertiary center in South India 维生素D缺乏及其与甲状腺过氧化物酶抗体阳性甲状腺功能减退症的关系——南印度一家三级中心的经验

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_252_16

J. Khare, Babul Reddy, S. Nalla, Prachi Srivastava, J. Wadhwa, P. Deb

{"title":"Vitamin D deficiency and its association with thyroid peroxidase antibodies positive hypothyroidism - Experience in a tertiary center in South India","authors":"J. Khare, Babul Reddy, S. Nalla, Prachi Srivastava, J. Wadhwa, P. Deb","doi":"10.4103/MJDRDYPU.MJDRDYPU_252_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_252_16","url":null,"abstract":"Introduction: Vitamin D deficiency is one of the major health problems globally, and the role of Vitamin D as an immunomodulator has been recently emphasized. There is increasing evidence to suggest that Vitamin D plays a significant role in reducing the incidence of autoimmune diseases. However, at present, its role in autoimmune thyroid disease is not conclusive. Hence, in our study, we aimed to examine the relationship between thyroid peroxidase antibodies (TPOAbs) and Vitamin D deficiency in the hypothyroid patient. Subjects and Methods: One hundred and four known hypothyroid patients not on Vitamin D supplementation were included in the study. They were divided into two groups with TPOAb positive and TPOAb negative, and serum 25(OH) Vitamin D3 (25[OH] D3) was measured and compared in two groups. Thyroid hormones (TSH and T4) were also evaluated in all patients. Results: Serum 25(OH)D3 was significantly lower in TPOAb-positive patients than in TPOAb-negative patients with P = 0.038. Mean serum TSH was significantly high in TPOAb-positive hypothyroid patients than in TPOAb-negative patients with P = 0.047. Conclusion: Our study shows that patients with TPOAb positivity have more significant 25(OH)D3 deficiency and uncontrolled hypothyroidism. Our study encourages the advisability of screening for Vitamin D deficiency for all hypothyroid patients and 25(OH)D3 supplementation.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"355"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47349182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Family planning paradigms: Gender bias and its impact on Olympic gold medals 计划生育范式:性别偏见及其对奥运金牌的影响

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_72_17

A. Banerjee

引用次数: 0

Diagnostic implication of mean platelet volume in thrombocytopenia 血小板平均体积对血小板减少症的诊断意义

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_306_16

I. Gulati, H. Kumar, J. Sheth, I. Dey

{"title":"Diagnostic implication of mean platelet volume in thrombocytopenia","authors":"I. Gulati, H. Kumar, J. Sheth, I. Dey","doi":"10.4103/MJDRDYPU.MJDRDYPU_306_16","DOIUrl":"https://doi.org/10.4103/MJDRDYPU.MJDRDYPU_306_16","url":null,"abstract":"Background: A well-known cause of thrombocytopenia is peripheral platelet destruction in which the circulating platelets are premature and large. Many times a bone marrow examination is conducted to find out the etiology of thrombocytopenia. Assessment of platelet parameters like mean platelet volume (MPV) generated by a hematology analyzer is also believed to be helpful for guiding the clinicians to identify such cases. Aims: This study aims to ascertain whether raised MPV correlates with thrombocytopenia due to hyperdestruction of platelets. Materials and Methods: This was 2 years unicentric prospective observational study which included 100 thrombocytopenic patients. Their clinical diagnosis, platelet counts, and MPV values were recorded. Peripheral blood smears (PBS) were also examined for megaplatelets. Each case was put in Group A (hyperdestructive etiology) or Group B (hypoproductive etiology). Results: Group A had 79 cases out of which 53 had an MPV value more than 10.5 fl. In the rest, although MPV was not prominently raised, the PBS did show megaplatelets. Group B had 21 cases, which were not associated with a high MPV. A receiver operating characteristic curve was plotted, and Youden's index was used to find out a cutoff value for MPV (8.5 fl) which gave the maximum sensitivity and specificity to discriminate thrombocytopenia cases of hyperdestructive etiology from the rest. Conclusion: MPV is an accurate, reliable, and easily obtained platelet parameter which is helpful in diagnosing the basic etiology of thrombocytopenia. It is also a less painful alternative than the bone marrow examination for the patient.","PeriodicalId":36033,"journal":{"name":"Medical Journal of Dr. D.Y. Patil University","volume":"10 1","pages":"370"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47329146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Reply to “Letter to Editor”- Reproductive health awareness among adolescent girls of a government school in an urban slum of Pune city 对"给编辑的信"的答复-浦那市城市贫民窟一所公立学校的青春期女孩的生殖健康意识

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_70_17

P. Shankar, P. Dudeja

引用次数: 0

Anesthesia for day-care surgeries: Current perspectives 日托手术的麻醉：当前观点

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/MJDRDYPU.MJDRDYPU_24_17

Sukhminder Jit Bajwa, Veenita Sharma, Ridhima Sharma, A. Singh

引用次数: 5

Intrapulmonary bronchogenic cyst 肺内支气管源性囊肿

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/0975-2870.213927

S. Phatak, Neeraj A. Patange

引用次数: 0

A comparative study of modified Hodge test and Carba NP test for detecting carbapenemase production in Gram-negative bacteria 改良Hodge试验和Carba-NP试验检测革兰氏阴性菌产碳青霉烯酶的比较研究

Medical Journal of Dr. D.Y. Patil University Pub Date : 2017-07-01 DOI: 10.4103/0975-2870.213930

S. Datta, R. Dey, J. Dey, Srijita Ghosh

引用次数: 9