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中华病理学杂志最新文献

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[Central nervous system sarcoma with ATXN1::DUX4 fusions: report of a case]. 中枢神经系统肉瘤合并ATXN1::DUX4融合1例报告。
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20240711-00452
Z T Yan, H Wang, Q Li
{"title":"[Central nervous system sarcoma with ATXN1::DUX4 fusions: report of a case].","authors":"Z T Yan, H Wang, Q Li","doi":"10.3760/cma.j.cn112151-20240711-00452","DOIUrl":"10.3760/cma.j.cn112151-20240711-00452","url":null,"abstract":"","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"181-183"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Exploration of oral and pharyngeal swabs in microsatellite instability detection]. 口腔咽拭子在微卫星不稳定性检测中的应用探讨
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20241014-00676
J Zheng, L L Ding, Q Q Fang, Y Q Pan
{"title":"[Exploration of oral and pharyngeal swabs in microsatellite instability detection].","authors":"J Zheng, L L Ding, Q Q Fang, Y Q Pan","doi":"10.3760/cma.j.cn112151-20241014-00676","DOIUrl":"10.3760/cma.j.cn112151-20241014-00676","url":null,"abstract":"","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"171-174"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinicopathological analysis of primary gastric oncocytic neuroendocrine tumors]. 原发性胃嗜酸细胞性神经内分泌肿瘤的临床病理分析
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20240926-00644
X Y She, S Zhao, H J Hua, Y Zheng, H Li, Q Y Wang
{"title":"[Clinicopathological analysis of primary gastric oncocytic neuroendocrine tumors].","authors":"X Y She, S Zhao, H J Hua, Y Zheng, H Li, Q Y Wang","doi":"10.3760/cma.j.cn112151-20240926-00644","DOIUrl":"10.3760/cma.j.cn112151-20240926-00644","url":null,"abstract":"","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"162-164"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ideal time of enzyme digestion in FISH detection of breast cancer and lymphoma]. 【FISH检测乳腺癌和淋巴瘤时酶消化的理想时间】。
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20240711-00453
H L Zhang, C Y Yang, C F Zhang, H Liu, H Chen, Y Liu
{"title":"[Ideal time of enzyme digestion in FISH detection of breast cancer and lymphoma].","authors":"H L Zhang, C Y Yang, C F Zhang, H Liu, H Chen, Y Liu","doi":"10.3760/cma.j.cn112151-20240711-00453","DOIUrl":"10.3760/cma.j.cn112151-20240711-00453","url":null,"abstract":"","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"175-177"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pathological diagnosis and differential diagnosis of anorectal neoplastic diseases]. 【肛肠肿瘤性疾病的病理诊断与鉴别诊断】。
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20240712-00456
R S Chen, Y Huang, X L Liu
{"title":"[Pathological diagnosis and differential diagnosis of anorectal neoplastic diseases].","authors":"R S Chen, Y Huang, X L Liu","doi":"10.3760/cma.j.cn112151-20240712-00456","DOIUrl":"10.3760/cma.j.cn112151-20240712-00456","url":null,"abstract":"","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"193-198"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Primary gallbladder SMARCA4-deficient undifferentiated malignant neoplasm: a clinicopathological analysis of two cases]. 【原发性胆囊smarca4缺失未分化恶性肿瘤2例临床病理分析】。
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20240512-00311
X Chen, J Fan, Z G Du, F N Niu
{"title":"[Primary gallbladder SMARCA4-deficient undifferentiated malignant neoplasm: a clinicopathological analysis of two cases].","authors":"X Chen, J Fan, Z G Du, F N Niu","doi":"10.3760/cma.j.cn112151-20240512-00311","DOIUrl":"10.3760/cma.j.cn112151-20240512-00311","url":null,"abstract":"","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"168-170"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Application of PMS2 and MSH6 double-antibody detection in screening of mismatch repair deficient tumors]. [PMS2和MSH6双抗体检测在错配修复缺陷肿瘤筛查中的应用]。
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20240531-00354
C S Wang, B Zhang, Q Sun, J Yang, X B Cui, H Y Wu
{"title":"[Application of PMS2 and MSH6 double-antibody detection in screening of mismatch repair deficient tumors].","authors":"C S Wang, B Zhang, Q Sun, J Yang, X B Cui, H Y Wu","doi":"10.3760/cma.j.cn112151-20240531-00354","DOIUrl":"10.3760/cma.j.cn112151-20240531-00354","url":null,"abstract":"<p><p><b>Objective:</b> To investigate whether the immunohistochemical results of two markers PMS2 and MSH6 (2-MMR) could replace the four markers MLH1, PMS2, MSH2 and MSH6 (4-MMR) to detect mismatch repair deficient (dMMR) cancers. <b>Methods:</b> A retrospective analysis was conducted with summary of immunohistochemical data from 7 867 cases of gastric cancer, colorectal cancer, endometrial cancer, and other diseases in the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China, from March 2018 to March 2023. The consistency of 2-MMR and 4-MMR results was examined. Microsatellite instability (MSI) and next-generation sequencing (NGS) were performed in patients with specific phenotypes. <b>Results:</b> The Cohen κ values of 2-MMR and 4-MMR in gastric cancer, colorectal cancer, endometrial cancer and other diseases were 0.88, 0.99, 0.88 and 1.00, respectively. The overall consistency, sensitivity and specificity were 0.97, 99.6%, and 100.0%, respectively. Both 2-MMR and 4-MMR could detect the difference between various clinicopathological features. 24 (0.3%) of the 7 867 patients were found to have a special phenotype of MMR, and 6 of them were selected for MSI and NGS molecular testing. MSI analysis showed MSI-H in all cases, while NGS found that 5 of them had MMR-related gene mutations and 1 had POLE p.S297F mutation. <b>Conclusions:</b> Compared with 4-MMR, 2-MMR has high consistency, specificity and sensitivity. The cases with special phenotype only account for extremely low proportion. Therefore, 4-MMR may be replaced with 2-MMR in dMMR screening.</p>","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"126-134"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Advances in the pathology of digestive system diseases in China over the past ten years: retrospect and prospect]. 【近十年来中国消化系统疾病病理学研究进展：回顾与展望】。
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20240924-00629
Y Lin, J H Lyu, H X Meng, W Sang, X Q Tao, W X Zhou
{"title":"[Advances in the pathology of digestive system diseases in China over the past ten years: retrospect and prospect].","authors":"Y Lin, J H Lyu, H X Meng, W Sang, X Q Tao, W X Zhou","doi":"10.3760/cma.j.cn112151-20240924-00629","DOIUrl":"10.3760/cma.j.cn112151-20240924-00629","url":null,"abstract":"<p><p>The incidence of digestive system diseases is high. So digestive system pathology is widely concerned. In the past 10 years, Chinese pathologists insist on hard work and have made significant progress. This article reviews the research and practice progress in digestive system tumors and non-tumors in the past 10 years, including the establishment of diagnostic criteria for gastrointestinal tract, hepatobiliary and pancreatic diseases, the establishment and classification of new diseases with special morphology, the classification and standard update of gastrointestinal and pancreatic neuroendocrine tumors, the progress of molecular pathology, and non-tumor lesions of the digestive system. The future development trend of digestive system pathology is also prospected.</p>","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"103-108"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Parafallopian tube STK11 adnexal tumor with ovarian sex cord tumour with annular tubules: report of a case]. [输卵管旁STK11附件肿瘤合并卵巢性索环状小管肿瘤1例]。
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20240820-00558
X X Pang, J J Yong, Z Y Wang, Y Y Li
{"title":"[Parafallopian tube STK11 adnexal tumor with ovarian sex cord tumour with annular tubules: report of a case].","authors":"X X Pang, J J Yong, Z Y Wang, Y Y Li","doi":"10.3760/cma.j.cn112151-20240820-00558","DOIUrl":"10.3760/cma.j.cn112151-20240820-00558","url":null,"abstract":"","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"187-189"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Research progress of very early onset and monogenic inflammatory bowel disease and pathological diagnosis]. 【极早发单基因炎性肠病的研究进展及病理诊断】。
中华病理学杂志 Pub Date : 2025-02-08 DOI: 10.3760/cma.j.cn112151-20241209-00838
J X Ye, X Y Shi
{"title":"[Research progress of very early onset and monogenic inflammatory bowel disease and pathological diagnosis].","authors":"J X Ye, X Y Shi","doi":"10.3760/cma.j.cn112151-20241209-00838","DOIUrl":"10.3760/cma.j.cn112151-20241209-00838","url":null,"abstract":"","PeriodicalId":35997,"journal":{"name":"中华病理学杂志","volume":"54 2","pages":"203-209"},"PeriodicalIF":0.0,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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