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The Paradox of Care: Burnout Among Healthcare Workers. 护理的悖论:医护人员的职业倦怠。
IF 4.1
PUBLIC HEALTH REVIEWS Pub Date : 2025-10-23 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1609096
Shevaun M Teo, Sonja Moore, Shweta Rao
{"title":"The Paradox of Care: Burnout Among Healthcare Workers.","authors":"Shevaun M Teo, Sonja Moore, Shweta Rao","doi":"10.3389/phrs.2025.1609096","DOIUrl":"10.3389/phrs.2025.1609096","url":null,"abstract":"","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1609096"},"PeriodicalIF":4.1,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12588885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Associations Between WaSH-Related Health Outcomes and Terrorist Activities in the Sahel: A Scoping Review. 探讨与wash有关的健康结果与萨赫勒地区恐怖主义活动之间的关系:范围审查。
IF 4.1
PUBLIC HEALTH REVIEWS Pub Date : 2025-10-23 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1608490
Linda Christina Beck, Branwen Nia Owen, Emma Scott, Mirko S Winkler, Anaïs Galli
{"title":"Exploring Associations Between WaSH-Related Health Outcomes and Terrorist Activities in the Sahel: A Scoping Review.","authors":"Linda Christina Beck, Branwen Nia Owen, Emma Scott, Mirko S Winkler, Anaïs Galli","doi":"10.3389/phrs.2025.1608490","DOIUrl":"10.3389/phrs.2025.1608490","url":null,"abstract":"<p><strong>Objectives: </strong>The G5 Sahel countries have faced political instability and terrorist activities for over a decade. With the regional lack of water, sanitation and hygiene (WaSH), there is an increased risk of adverse health outcomes. This scoping review aims to document WaSH-related health outcomes associated with terrorist activities, identify gaps in the humanitarian and political response and propose actionable recommendations to address them.</p><p><strong>Methods: </strong>We followed the PRISMA standards, including literature from PubMed and Web of Science. Country-specific timeframes for terrorist activities were used.</p><p><strong>Results: </strong>Data was extracted from 54 out of 2,320 publications on 22 December 2023. While malnutrition and diarrheal diseases were frequently reported as health outcomes - consistent with inadequate WaSH services - the lack of studies directly linking these outcomes to terrorist activities is notable. Only one article explicitly established a direct link between health outcomes and terrorist activities.</p><p><strong>Conclusion: </strong>The scarcity of studies directly linking terrorist activities to health outcomes reveals a significant research gap and highlight the need for more focused investigations into the health impacts of political violence in the Sahel region.</p>","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1608490"},"PeriodicalIF":4.1,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12588887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reconstruction of the Discourse on Influenza During Pandemics Between 1889 and 1980 in the Predecessor Journal of Swiss Medical Weekly - A Narrative Review and Bibliometric Analysis. 1889年至1980年瑞士医学周刊的前身杂志上关于流感大流行期间的话语重建-叙述回顾和文献计量分析。
IF 5.2
PUBLIC HEALTH REVIEWS Pub Date : 2025-10-21 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1608522
Natalija Radivojevic, Milo Puhan, Kaspar Staub, Tala Ballouz
{"title":"Reconstruction of the Discourse on Influenza During Pandemics Between 1889 and 1980 in the Predecessor Journal of Swiss Medical Weekly - A Narrative Review and Bibliometric Analysis.","authors":"Natalija Radivojevic, Milo Puhan, Kaspar Staub, Tala Ballouz","doi":"10.3389/phrs.2025.1608522","DOIUrl":"10.3389/phrs.2025.1608522","url":null,"abstract":"<p><strong>Objectives: </strong>Understanding how discourse surrounding influenza pandemics evolves over time can reveal shifts in scientific and public health priorities. This study reconstructs such discourse between 1889 and 1981 by identifying and comparing key research themes and trends in articles in predecessor journals of Swiss Medical Weekly (SMW).</p><p><strong>Methods: </strong>A corpus of articles containing the terms \"influenza,\" \"flu,\" and \"epidemic\" from five pandemic periods was compiled. We conducted a keyword-based content analysis, categorizing articles into 31 sub-keywords within five broad categories, and comparing their frequencies. Co-occurrence maps were generated using VOSviewer, and relevant articles were closely read.</p><p><strong>Results: </strong>A total of 352 articles were identified, with the highest number published between 1918 and 1924. Most prevalent themes across all periods were \"Epidemiology and disease dynamics,\" \"Complications,\" and \"Acute clinical manifestations and management.\" A key shift in focus occurred with the introduction of influenza vaccination after the 1940s, as attention increasingly turned towards immunity and the role of vaccinations.</p><p><strong>Conclusion: </strong>Despite major medical developments, similar themes were seen across the observed pandemic periods in SMW. This study provides an important first step towards constructing such discourses.</p>","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1608522"},"PeriodicalIF":5.2,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12583112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations Between Occupational Exposures to Volatile Organic Compounds (VOCs) and Sleep Problems. 职业性接触挥发性有机化合物(VOCs)与睡眠问题的关系。
IF 4.1
PUBLIC HEALTH REVIEWS Pub Date : 2025-09-25 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1608224
Amir Hossein Khoshakhlagh, Saeid Yazdanirad, Christopher Drake, Justin Iqal, Dinh Bui
{"title":"Associations Between Occupational Exposures to Volatile Organic Compounds (VOCs) and Sleep Problems.","authors":"Amir Hossein Khoshakhlagh, Saeid Yazdanirad, Christopher Drake, Justin Iqal, Dinh Bui","doi":"10.3389/phrs.2025.1608224","DOIUrl":"10.3389/phrs.2025.1608224","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study, as a systematic review and meta-analysis, is to summarize the evidence on the effects of occupational exposure to VOCs on sleep quality.</p><p><strong>Methods: </strong>We used five electronic bibliographic databases to identify eligible studies. Three groups of keywords were applied in the search strategy. In evaluating the quality of studies and risk of bias, we utilized the Joanna Briggs Institute tools and the Risk of Bias in Non-randomized Studies of Exposures (ROBINS-E) instruments, respectively. The pooled values were also calculated by meta-analysis.</p><p><strong>Results: </strong>37 articles were included in the study. There was a consistent finding that exposure to volatile organic compounds (VOCs) adversely affected sleep in workers across various professions. The pooled value of the odds ratio of sleep problems because of exposure to VOCs was 1.60 [95% CI (1.01, 2.19)].</p><p><strong>Conclusion: </strong>Most studies indicated that occupational exposure to VOCs can significantly influence the sleep of workers in various professions. The exposure can be associated with a variety of sleep problems.</p>","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1608224"},"PeriodicalIF":4.1,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic Review of Financing Functions for Universal Health Coverage in Low- and Middle-Income Countries: Reforms, Challenges, and Lessons Learned. 低收入和中等收入国家全民健康覆盖筹资职能的系统审查:改革、挑战和经验教训。
IF 4.1
PUBLIC HEALTH REVIEWS Pub Date : 2025-09-23 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1607745
Othmane Hajji, Bouchra El Abbadi, El Houcine Akhnif
{"title":"Systematic Review of Financing Functions for Universal Health Coverage in Low- and Middle-Income Countries: Reforms, Challenges, and Lessons Learned.","authors":"Othmane Hajji, Bouchra El Abbadi, El Houcine Akhnif","doi":"10.3389/phrs.2025.1607745","DOIUrl":"10.3389/phrs.2025.1607745","url":null,"abstract":"<p><strong>Objective: </strong>The systematic review reveals a lack of research on financing universal health coverage (UHC) in low- and middle-income countries (LMICs). This study aims to examine the financing mechanisms used, identify the main challenges faced, and gather insights from successful experiences to inform future reforms in LMICs.</p><p><strong>Methods: </strong>We conducted a literature search across seven academic databases, limiting our systematic review to studies published in English and French between 2010 and 2022, which were then included in our qualitative analysis.</p><p><strong>Results: </strong>A total of 45 studies met the inclusion criteria-most used qualitative (n = 23) or documentary (n = 15) approaches. The majority (n = 37) were published between 2015 and 2022. Using Kutzin's framework, we analyzed health financing functions in LMICs. Key challenges and lessons learned were summarized to improve understanding of ongoing financing issues and opportunities for reform.</p><p><strong>Conclusion: </strong>This study emphasizes key financing strategies and ongoing challenges in LMICs and provides specific recommendations for countries to prioritize reforms and address health financing gaps. The goal is to speed up progress toward UHC.</p>","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1607745"},"PeriodicalIF":4.1,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12501465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145252998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of Adolescent Sexual Behavior in Sub-Saharan Africa: A Systematic Review of In-School and Out-of-School Adolescents. 撒哈拉以南非洲青少年性行为的决定因素:对在校和校外青少年的系统回顾。
IF 4.1
PUBLIC HEALTH REVIEWS Pub Date : 2025-09-23 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1608357
Ruth-Janet Koumba Maguena, Sara Alves Jorge, Edgard Brice Ngoungou, Stephan Van den Broucke
{"title":"Determinants of Adolescent Sexual Behavior in Sub-Saharan Africa: A Systematic Review of In-School and Out-of-School Adolescents.","authors":"Ruth-Janet Koumba Maguena, Sara Alves Jorge, Edgard Brice Ngoungou, Stephan Van den Broucke","doi":"10.3389/phrs.2025.1608357","DOIUrl":"10.3389/phrs.2025.1608357","url":null,"abstract":"<p><strong>Objectives: </strong>This review aims to identify the main determinants of various sexual behaviors among in-school and out-of-school adolescents in sub-Saharan Africa, using Bronfenbrenner's ecological system theory as a framework.</p><p><strong>Methods: </strong>A systematic review with narrative synthesis was performed of empirical studies about the determinants of sexual behavior among in-school and out-of-school adolescents aged 10 to 19 in sub-Saharan Africa, using quantitative data from Embase, PubMed, PsycInfo, SCOPUS, AJOL, and Google Scholar.</p><p><strong>Results: </strong>A total of 132 studies were retrieved, identifying determinants of sexual behaviors such as sexual intercourse, sexual initiation at early age, multipartnership, condom use, contraceptive use, sexual abstinence, or sexual violence. Only four of these 132 studies involved out-of-school adolescents. Determinants of adolescent sexual behavior include demographic characteristics, socio-cognitive factors, problem behaviors, experiences, family relations, peers' influence, relationships, school dynamics, education system, health system, information system, sociodemographic characteristics, socio-economic characteristics, religion, and societal values and norms.</p><p><strong>Conclusion: </strong>To design interventions that address adolescents' sexual and reproductive health needs, public health policymakers must consider the multifaceted and interconnected determinants of sexual behaviors among in-school and out-of-school adolescents.</p>","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1608357"},"PeriodicalIF":4.1,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12501466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving the Conduct of Health-Related Research in Schools. 改善学校健康相关研究的行为。
IF 4.1
PUBLIC HEALTH REVIEWS Pub Date : 2025-08-21 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1608316
Alessia Raineri, Manuel Weber, Seraina Rüegger, Susi Kriemler, Milo A Puhan
{"title":"Improving the Conduct of Health-Related Research in Schools.","authors":"Alessia Raineri, Manuel Weber, Seraina Rüegger, Susi Kriemler, Milo A Puhan","doi":"10.3389/phrs.2025.1608316","DOIUrl":"10.3389/phrs.2025.1608316","url":null,"abstract":"<p><strong>Background: </strong>Schools serve not only as centers of education but also as critical environments for social development and promoting health and well-being of children and adolescents. Conducting health-related research in school settings offers valuable opportunities to identify current health challenges and assess preventive and interventional strategies.</p><p><strong>Analysis: </strong>Researchers face several challenges when conducting health-related research in schools, including communication barriers, complex coordination among relevant stakeholders, and limited resources.</p><p><strong>Policy options: </strong>This policy brief, with a special focus on Switzerland, highlighted main challenges and presented options derived from literature, semi-structured interviews, and a stakeholder dialogue to address them. The dialogue included representatives from youth, parents, teachers, school principals, school authorities, and researchers. The results emphasize key options in three main areas: (i) recruitment and motivation, (ii) retention and incentives, and (iii) partnerships and collaboration.</p><p><strong>Conclusion: </strong>Many of the proposed options do not require large-scale political shifts nor national-level policy changes but can directly be applied in schools and research settings, emphasizing their practical applicability and potential for immediate impact. Ultimately, implementing these options in health-related research in schools can contribute to long-term health and well-being of future generations.</p>","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1608316"},"PeriodicalIF":4.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strengthening Outbreak Detection in Africa to Achieve the 7-1-7 Global Framework: Challenges and Opportunities. 加强非洲疫情检测以实现7-7-7全球框架:挑战与机遇。
IF 4.1
PUBLIC HEALTH REVIEWS Pub Date : 2025-08-14 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1608039
Frantz Jean Louis, Lisa Nichols, Cristina de la Torre, Anicet G Dahourou
{"title":"Strengthening Outbreak Detection in Africa to Achieve the 7-1-7 Global Framework: Challenges and Opportunities.","authors":"Frantz Jean Louis, Lisa Nichols, Cristina de la Torre, Anicet G Dahourou","doi":"10.3389/phrs.2025.1608039","DOIUrl":"10.3389/phrs.2025.1608039","url":null,"abstract":"<p><strong>Objectives: </strong>Timely detection of infectious disease outbreaks is essential to limit health, social, and economic impacts, yet diagnostic and surveillance gaps persist across Africa. This review applies the 7-1-7 global target framework-detect within 7 days, notify within 1, and respond within 7-to assess strategies for strengthening early detection capacities across African countries.</p><p><strong>Methods: </strong>We conducted a review of peer-reviewed literature, institutional reports, and field evidence published without time span limitations. Key themes were organized around five strategic pillars: diagnostic preparedness, surveillance, workforce development, community engagement, and governance.</p><p><strong>Results: </strong>Identified bottlenecks include limited diagnostic networks capacity, fragmented surveillance systems, workforce shortages, and underinvestment in digital infrastructure. Promising solutions include diagnostic network optimization, deployment of point-of-care molecular tools, integration of event- and indicator-based surveillance through interoperable platforms, and AI-enabled early warning systems. Field examples from Uganda, Senegal, and Nigeria demonstrate improved timeliness where coordinated investments and multisectoral collaboration have been implemented.</p><p><strong>Conclusion: </strong>Meeting the 7-1-7 detection target requires integrated, country-owned strategies that align diagnostics, surveillance, workforce, and governance within resilient national health security frameworks, underpinned by sustained domestic investment.</p>","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1608039"},"PeriodicalIF":4.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive and Negative Family Relationships Correlate With Mental Health Conditions -a Systematic Review and Meta-Analysis. 积极和消极的家庭关系与心理健康状况相关——系统回顾和荟萃分析。
IF 4.1
PUBLIC HEALTH REVIEWS Pub Date : 2025-07-21 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1607381
Jutta Lindert, Sarah Arndt, Natalie Cook, Paul A Bain, Ichiro Kawachi
{"title":"Positive and Negative Family Relationships Correlate With Mental Health Conditions -a Systematic Review and Meta-Analysis.","authors":"Jutta Lindert, Sarah Arndt, Natalie Cook, Paul A Bain, Ichiro Kawachi","doi":"10.3389/phrs.2025.1607381","DOIUrl":"10.3389/phrs.2025.1607381","url":null,"abstract":"<p><strong>Objectives: </strong>We aim to investigate the association between family relationships and mental health conditions in adults aged 18+.</p><p><strong>Methods: </strong>We conducted a systematic review on associations of family relationships and mental health conditions by searching in databases MEDLINE, Embase, Web of Science Core Collection, PsycINFO, Sociological Abstracts (ProQuest), and PTSDPubs. We calculated the Pearson correlation coefficients and I2 statistics using a random-effects model. Additionally, we investigated publication bias using funnel plots.</p><p><strong>Results: </strong>Of the 3,707 records screened, 40 with n = 35,634 participants met the inclusion criteria (38.5% male, 59.5% female, mean age 39.57), were conducted mostly in North America (n = 27). Positive family relationships were investigated in 33 studies, negative relationships in 12 studies. Positive family relationships were not statistically significantly associated with depression [r = -0.071 (-0.256, 0.119), p = 0.463, anxiety r = 0.026 (-0.032, 0.084), p = 0.375] or alcohol abuse [r = 0.035 (-0.103, 0.0034), p=0.326]. Positive family relationships were statistically significantly associated with illicit drug use [r = 0.061 (0.025, 0.096), p = 0.001]. Negative family relationships were statistically significantly associated with anxiety [r = 0.075 (0.019, 0.130), p = 0.009], and with depression [r = 0.111 (0.033, 0.188), p = 0.005].</p><p><strong>Conclusion: </strong>Interventions reducing negative family relationships can potentially strengthen positive mental health.</p>","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1607381"},"PeriodicalIF":4.1,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic and Epigenetic Alterations Associated With Human Prenatal Tobacco and Environmental Tobacco Smoke Exposure: Protocol for a Systematic Evidence Map. 与人类产前烟草和环境烟草烟雾暴露相关的遗传和表观遗传改变:系统证据图的协议。
IF 4.1
PUBLIC HEALTH REVIEWS Pub Date : 2025-07-14 eCollection Date: 2025-01-01 DOI: 10.3389/phrs.2025.1606742
Ana Teresa Reis, Joana Madureira, João Paulo Teixeira, Carla Costa
{"title":"Genetic and Epigenetic Alterations Associated With Human Prenatal Tobacco and Environmental Tobacco Smoke Exposure: Protocol for a Systematic Evidence Map.","authors":"Ana Teresa Reis, Joana Madureira, João Paulo Teixeira, Carla Costa","doi":"10.3389/phrs.2025.1606742","DOIUrl":"10.3389/phrs.2025.1606742","url":null,"abstract":"<p><strong>Objectives: </strong>This protocol outlines the development of a systematic evidence map (SEM) on genetic and epigenetic alterations associated with human prenatal tobacco exposure. The SEM will identify and synthetize epidemiological data on periconceptional and prenatal tobacco exposure associated with genetic (e.g., DNA damage) and epigenetic (e.g., DNA methylation) outcomes. Furthermore, it will describe the available evidence, highlight knowledge clusters, and identify gaps for future research.</p><p><strong>Methods: </strong>Bibliographic databases and grey literature sources will be searched, complemented by reference mining. Predefined inclusion and exclusion criteria will guide study inclusion. Data extraction will include population, exposure, comparator, outcome, funding, study design, confounding factors, and statistical methods. Summarization will include a narrative review, graphical visualization, and an interactive, queryable and open-access table.</p><p><strong>Results: </strong>A pilot study assessed the protocol's feasibility, testing key components, including screening, data extraction, and eligibility criteria. Findings confirmed that the methodology is workable and reliable.</p><p><strong>Conclusion: </strong>This protocol supports a rigorous, reproducible, transparent SEM, aligned with international standards. The comprehensive mapping will support research prioritization and inform public health policies targeting maternal and child health.</p>","PeriodicalId":35944,"journal":{"name":"PUBLIC HEALTH REVIEWS","volume":"46 ","pages":"1606742"},"PeriodicalIF":4.1,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12301260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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