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Japanese Journal of Leprosy最新文献

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「ハンセン病文庫友の会」11年の活動の歴史とその意義について 关于“麻风病文库友会”11年活动的历史及其意义
Japanese Journal of Leprosy Pub Date : 2020-01-01 DOI: 10.5025/hansen.89.19
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引用次数: 0
「近現代ハンセン病資料アーカイブス」の公開と今後の展開 “近现代麻风病资料档案”的公开与今后的发展
Japanese Journal of Leprosy Pub Date : 2020-01-01 DOI: 10.5025/hansen.89.13
{"title":"「近現代ハンセン病資料アーカイブス」の公開と今後の展開","authors":"","doi":"10.5025/hansen.89.13","DOIUrl":"https://doi.org/10.5025/hansen.89.13","url":null,"abstract":"","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70683761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maxillary bone deformation in patients with leprosy: a novel method for quantitative evaluation by CT scan 麻风病患者上颌骨变形:CT扫描定量评估的新方法
Japanese Journal of Leprosy Pub Date : 2019-01-01 DOI: 10.5025/hansen.88.43
Norio Kasai
{"title":"Maxillary bone deformation in patients with leprosy: a novel method for quantitative evaluation by CT scan","authors":"Norio Kasai","doi":"10.5025/hansen.88.43","DOIUrl":"https://doi.org/10.5025/hansen.88.43","url":null,"abstract":"","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70683692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mycolactone is toxic to cultured Schwann cells - mechanism of nerve damage in Buruli ulcer 菌内酯对培养的雪旺细胞有毒性——布鲁里溃疡神经损伤的机制
Japanese Journal of Leprosy Pub Date : 2019-01-01 DOI: 10.5025/HANSEN.87.123
Junichiro En
{"title":"Mycolactone is toxic to cultured Schwann cells - mechanism of nerve damage in Buruli ulcer","authors":"Junichiro En","doi":"10.5025/HANSEN.87.123","DOIUrl":"https://doi.org/10.5025/HANSEN.87.123","url":null,"abstract":"A toxic lipid mycolactone produced from to block the sensory system of the either by direct cellular damage (cytotoxicity) to the regional nerve tissue, or by a more sophisticated, non-toxic paralyzing mechanism. In the peripheral nerve, Schwann cells nourish axons and accelerate nerve conduction. In this study, we have compared the cytotoxic potential of mycolactone on cultured Schwann cells and that on fibroblasts, and found that mycolactone A/B induced much higher cell death and apoptosis in Schwann cell line SW10 than in fibroblast line L929. We demonstrated the cytotoxicity of synthetic mycolactone A/B and its remote diastereomer in mouse Schwann cells as well as fibroblasts and macrophages. A quantitative study showed that Schwann cells are relatively more sensitive than fibroblasts to mycolactone 24 and 48 hrs after exposure to mycolactone A/B diastereomer. The painless nature of Buruli ulcer may be caused by the cytotoxicity of mycolactone A/B in","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70684076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
沖縄の多彩な皮膚病の現状と、疾患背景の理解 冲绳多种皮肤病的现状和疾病背景的理解
Japanese Journal of Leprosy Pub Date : 2019-01-01 DOI: 10.5025/hansen.88.39
{"title":"沖縄の多彩な皮膚病の現状と、疾患背景の理解","authors":"","doi":"10.5025/hansen.88.39","DOIUrl":"https://doi.org/10.5025/hansen.88.39","url":null,"abstract":"","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70684087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Study on the Entering and Out-going Trends at Japan’s National Hansen’s Disease Sanatoriums 日本国立汉森病疗养院的进出趋势研究
Japanese Journal of Leprosy Pub Date : 2019-01-01 DOI: 10.5025/hansen.88.53
S. Mori, M. Ato, N. Ishii
{"title":"A Study on the Entering and Out-going Trends at Japan’s National Hansen’s Disease Sanatoriums","authors":"S. Mori, M. Ato, N. Ishii","doi":"10.5025/hansen.88.53","DOIUrl":"https://doi.org/10.5025/hansen.88.53","url":null,"abstract":"","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5025/hansen.88.53","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70683705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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