Japanese Journal of Leprosy最新文献

{"title":"「ハンセン病文庫友の会」11年の活動の歴史とその意義について","authors":"","doi":"10.5025/hansen.89.19","DOIUrl":"https://doi.org/10.5025/hansen.89.19","url":null,"abstract":"","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70683798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"「近現代ハンセン病資料アーカイブス」の公開と今後の展開","authors":"","doi":"10.5025/hansen.89.13","DOIUrl":"https://doi.org/10.5025/hansen.89.13","url":null,"abstract":"","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70683761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maxillary bone deformation in patients with leprosy: a novel method for quantitative evaluation by CT scan","authors":"Norio Kasai","doi":"10.5025/hansen.88.43","DOIUrl":"https://doi.org/10.5025/hansen.88.43","url":null,"abstract":"","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70683692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycolactone is toxic to cultured Schwann cells - mechanism of nerve damage in Buruli ulcer","authors":"Junichiro En","doi":"10.5025/HANSEN.87.123","DOIUrl":"https://doi.org/10.5025/HANSEN.87.123","url":null,"abstract":"A toxic lipid mycolactone produced from to block the sensory system of the either by direct cellular damage (cytotoxicity) to the regional nerve tissue, or by a more sophisticated, non-toxic paralyzing mechanism. In the peripheral nerve, Schwann cells nourish axons and accelerate nerve conduction. In this study, we have compared the cytotoxic potential of mycolactone on cultured Schwann cells and that on fibroblasts, and found that mycolactone A/B induced much higher cell death and apoptosis in Schwann cell line SW10 than in fibroblast line L929. We demonstrated the cytotoxicity of synthetic mycolactone A/B and its remote diastereomer in mouse Schwann cells as well as fibroblasts and macrophages. A quantitative study showed that Schwann cells are relatively more sensitive than fibroblasts to mycolactone 24 and 48 hrs after exposure to mycolactone A/B diastereomer. The painless nature of Buruli ulcer may be caused by the cytotoxicity of mycolactone A/B in","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70684076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"沖縄の多彩な皮膚病の現状と、疾患背景の理解","authors":"","doi":"10.5025/hansen.88.39","DOIUrl":"https://doi.org/10.5025/hansen.88.39","url":null,"abstract":"","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70684087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study on the Entering and Out-going Trends at Japan’s National Hansen’s Disease Sanatoriums","authors":"S. Mori, M. Ato, N. Ishii","doi":"10.5025/hansen.88.53","DOIUrl":"https://doi.org/10.5025/hansen.88.53","url":null,"abstract":"","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5025/hansen.88.53","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70683705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A Study on the Entering and Out-going Trends at Japan’s National Hansen’s Disease Sanatoriums].","authors":"Shuichi Mori,&nbsp;Norihisa Ishii","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A Hansen’s disease (HD) policy began in Japan with the enactment of the No. 11 Act on Leprosy (1907 law No. 11), which was the first leprosy prevention law in Japan in 1907. Results of the law included the enforcement of regulations of the stated law and the establishment of Prefectural Allied (National) HD Sanatoriums in 1909. This policy continued until the “leprosy prevention law” abolition in 1996, and about 35,000 people were placed in isolation; however, its entering and out-going trends are not clear yet. The purpose of this research is to clarify the actual condition of the Japanese HD policy.\u0000\u0000 We added up the number of individuals entering and leaving the sanatorium from 1909 to 2010. This information was collected from annual reports and the internal material from each national sanatorium. In the results, the number of general residents (new, re-entering, transferring from other sanatoriums) and the number of general out-going persons (transferring to another sanatorium, formal discharge, informal discharge including escape and wrong diagnosis, and others) were all totaled as the running number during the 102 year span, in addition to being added to the deaths. The results show that the number of general residents was 56,575 people and the number of general out-going persons was 54,047 people (death: 25,200 people; change of sanatorium: 4,350 people; formal discharge: 7,124 people; informal discharge including escape: 12,378 people; wrong diagnosis: 310 people; others: 4,685 people).\u0000\u0000 Based on the details of each leprosy prevention law, the results for the first “1907 law No. 11” show that the number of general residents was 12,673 people and the number of general out-going persons was 9,070 people. The “1931 leprosy prevention law” results show that the number of general residents was 31,232 people and the number of general out-going persons was 23,354 people. The “1953 leprosy prevention law” results show that the number of general inmates was 12,098 people and the number of general out-going persons was 18,159 people. The “1996 law about repeal of leprosy prevention law” results show that the number of general residents was 572 people and the number of general out-going persons was 3,464 people.\u0000\u0000 We can clarify the number of general residents and the number of general out-going persons in the National HD Sanatoriums in Japan.</p>","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36433114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[An example of the socio-economic rehabilitation program for ex-leprosy patients in Vietnam and its evaluation by the patients].","authors":"Hiroyuki Watanabe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One of the leprosy treatment centers (hospital X) in Vietnam offers loan programs to start work as part of the socio-economic rehabilitation program for ex-leprosy patients. The aim of this study is to examine and evaluate the contents of the program from the ex-leprosy patients’ perspective. The interview group was sub-divided into three groups: male/female and the younger group. A focus group interview method was used to collect qualitative data. The participant program group revealed that their income increased and their health condition improved; moreover, they evaluated the program highly as they can borrow business loan at no interest. Meanwhile, the participants were challenged with a few problems: the frequency in the illness of the livestock and the forcible discounting in the livestock’s price by the customers who use the excuse that the livestock has been raised by ex-leprosy patients. The younger group had concerns regarding the program; they were worried about the repayment of the business loan. Both groups noted points to improve the current program especially in terms of changing the loan repayment schedule and loan volume. Therefore, the program has to be adapted to the needs of ex-leprosy patients.</p>","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36430621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The Structure of Practices and Tasks of Death Watch Care of Residents in the A National Sanatorium for Hansen’s Disease].","authors":"Hiroyuki Iha","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study aims to clarify the structure of practices and tasks of death watch care in the A National Sanatorium for Sufferers of Hansen’s Disease (shown as A Sanatorium). A semi-structured interview was conducted of four nurses with experience of death watch care. Then, it was analyzed using the qualitative unification methods (KJ methods) individually and comprehensively. According to the results of the comprehensive analysis, nurses tended to feel strongly toward “a necessity of death watch care with a focus on family” through their communication with residents with poor relationships with their families. With this feeling in mind, they were placed everyday in “death watch care, focusing on supporting resident’s lives through daily care” while trying to be conscious of life-support for them. In practice every day, they seemed to be satisfied and encouraged by “tasks of death care are to focus on the resident’s value of life.” However, nurses with little experience of death watch care were full of anxiety and dilemmas emerged when they began death watch care. During this process, it was verified that there was “a gap in consciousness among nurses administering death watch care” and “an uncertainness of policies of institutions that accepted the death watch of residents.” In this way, an method for future death watch care in A Sanatorium was shown.</p>","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36430620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Health-related quality of life, depression, and self-esteem in adolescents with leprosy-affected parents: results of a cross-sectional study in Nepal].","authors":"Nobuko Yamaguchi,&nbsp;Krishna Poudel,&nbsp;Mesamine Jimba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Leprosy is a chronic infectious disease that has an impact on the Health-Related Quality of Life (HRQOL) of sufferers as well as their children. To date, no study has investigated the effects of parental leprosy on the well-being of adolescent children.\u0000\u0000A cross-sectional study was conducted in the Lalitpur and Kathmandu districts of Nepal. Adolescents with leprosy-affected parents (n=102; aged 11-17 years) and those with parents unaffected by leprosy (n=115; 11-17 years) were investigated. Self-reported data from adolescents were collected using the Kinder Lebensqualität Fragebogen (KINDLR) questionnaire to assess HRQOL, the Center for Epidemiological Studies-Depression Scale (CES-D), and the Rosenberg Self-esteem Scale (RSES). Analysis of covariance (ANCOVA) was used to compare scores between the two groups. Multiple regression analysis was conducted to explore the determinants of HRQOL for adolescents with leprosy-affected parents.\u0000\u0000ANCOVA revealed that the KINDLR and RSES scores were significantly lower among adolescents with leprosy-affected parents compared with unaffected parents. The CES-D score was significantly higher among adolescents with leprosy-affected parents than for adolescents with unaffected parents. The KINDLR scores for adolescents with both parents affected were significantly lower than the scores for those with one parent affected. Multiple regression analysis revealed that adolescents with leprosy-affected parents who had higher levels of depressive symptoms were more likely to have lower KINDLR scores. A similar result was seen for adolescents where both parents had leprosy.\u0000\u0000Adolescents with leprosy-affected parents had higher levels of depressive symptoms, lower levels of self-esteem, and lower HRQOL compared with adolescents whose parents were unaffected by leprosy.</p>","PeriodicalId":35918,"journal":{"name":"Japanese Journal of Leprosy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36430618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}