Ecletica Quimica最新文献_第2页

Potential inhibiting activities of phytochemicals in Scilla natalensis bulbs against schistosomiasis 甜菜球茎植物化学物质对血吸虫病的潜在抑制作用

Ecletica Quimica Pub Date : 2023-07-01 DOI: 10.26850/1678-4618eqj.v48.3.2023.p54-80

A. Oyebamiji, J. Babalola, K. Odelade, S. Akintelu, Olubunmi Ayoola Nubi, H. Aworinde, E. Faboro, E. Akintayo, B. Semire

{"title":"Potential inhibiting activities of phytochemicals in Scilla natalensis bulbs against schistosomiasis","authors":"A. Oyebamiji, J. Babalola, K. Odelade, S. Akintelu, Olubunmi Ayoola Nubi, H. Aworinde, E. Faboro, E. Akintayo, B. Semire","doi":"10.26850/1678-4618eqj.v48.3.2023.p54-80","DOIUrl":"https://doi.org/10.26850/1678-4618eqj.v48.3.2023.p54-80","url":null,"abstract":"Schistosomiasis remains one of the severe ailments that affect both man and woman in South Africa. It is caused by blood fluke, and the rate at which it causes death is alarming in some areas of America, Asia as well as in African countries. It is a neglected tropical disease (NTD) with grave impact on social and economic situation of countries with low sanitation awareness. Thus, the search for lasting solution to this menace, has drawn the attention of many global researchers using phytochemicals from Scilla natalensis via in silico approach. The studied compounds were optimized using Spartan 14. Docking study was executed via Pymol, Autodock tool, Auto dock vina and discovery studio. Compound 9 with –8.2 kcal mol–1 and –9.4 kcal mol–1 as binding affinity proved to possess highest ability to inhibit glutathione S-transferase and thioredoxin-glutathione reductase than other compounds. Also, ADMET properties for compound 9 and praziquantel were explored and reported. Our findings may open the door for the design of novel drug-like molecules with better efficiency.","PeriodicalId":35894,"journal":{"name":"Ecletica Quimica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76142218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The potency of cooperative integrated reading and composition in building chemistry students’ scientific literacy and self-regulated learning 合作综合阅读与写作在培养化学学生科学素养与自主学习中的作用

Ecletica Quimica Pub Date : 2023-07-01 DOI: 10.26850/1678-4618eqj.v48.3.2023.p27-35

Habiddin Habiddin, Cyndi Yanis Saputri, Aman Santoso

{"title":"The potency of cooperative integrated reading and composition in building chemistry students’ scientific literacy and self-regulated learning","authors":"Habiddin Habiddin, Cyndi Yanis Saputri, Aman Santoso","doi":"10.26850/1678-4618eqj.v48.3.2023.p27-35","DOIUrl":"https://doi.org/10.26850/1678-4618eqj.v48.3.2023.p27-35","url":null,"abstract":"The effect of the Cooperative Integrated Reading and Composition (CIRC) approach on scientific literacy and students’ regulated learning in colligative properties of solution was explored. The contribution of the CIRC approach was measured by investigating whether the improvement in scientific literacy and regulated learning of the CIRC students are more significant than the improvement for students with the Direct Instructional Teaching Method (DITM) after experiencing two different teaching approaches. Two groups of students (experiment and comparison) from a public senior high school in East Java, Indonesia, were involved. The experimental group experienced the colligative properties of solution with the CIRC teaching approach, while the comparison group experienced the DITM one. We found that scientific literacy and self-regulated learning of students with CIRC are higher than students with DITM, implying the potency of this approach to be applied to other chemistry topics. This study indicates that CIRC could be used to improve students’ scientific literacy and self-regulated learning for other chemistry topics. The implication of this study for teaching colligative properties of solution is also discussed.","PeriodicalId":35894,"journal":{"name":"Ecletica Quimica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78256093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel organophosphorus Schiff base ligands: Synthesis, characterization, ligational aspects, XRD and biological activity studies 新型有机磷席夫碱配体:合成、表征、连接、XRD和生物活性研究

Ecletica Quimica Pub Date : 2023-07-01 DOI: 10.26850/1678-4618eqj.v48.3.2023.p36-53

Y. Jamil, F. Al-Azab, N. Al-Selwi

引用次数: 0

Oil extraction from seeds of Carica papaya L.: Obtaining the lipid profile and thermal evaluation 番木瓜籽油的提取:脂质特征及热评价

Ecletica Quimica Pub Date : 2023-07-01 DOI: 10.26850/1678-4618eqj.v48.3.2023.p81-90

M. Fonseca, M. Kobelnik, G. G. Fontanari, M. Crespi, C. A. Ribeiro

引用次数: 0

Chemical variability of phenolic compounds in Phyllanthus niruri 余甘子酚类化合物的化学变异

Ecletica Quimica Pub Date : 2023-07-01 DOI: 10.26850/1678-4618eqj.v48.3.2023.p17-26

I. Albrecht, Natalia Coelho Da Silva, F. A. Carvalho, F. Oda, A. D. dos Santos

引用次数: 0

Synthesis of some new substituted imines from aldehydes and ketones derived from quinolinic acid 喹啉酸衍生的醛类和酮类合成新取代亚胺

Ecletica Quimica Pub Date : 2023-04-01 DOI: 10.26850/1678-4618eqj.v48.2.2023.p49-65

A. Fathi, Yassir Shakeeb Al Jawaheri, Shaimaa Samir Ismaee

{"title":"Synthesis of some new substituted imines from aldehydes and ketones derived from quinolinic acid","authors":"A. Fathi, Yassir Shakeeb Al Jawaheri, Shaimaa Samir Ismaee","doi":"10.26850/1678-4618eqj.v48.2.2023.p49-65","DOIUrl":"https://doi.org/10.26850/1678-4618eqj.v48.2.2023.p49-65","url":null,"abstract":"In this paper, some substituted imines compounds have been prepared from quinolinic acid as a starting material. Firstly, the quinolinic acid was treated with acetic anhydride and acetic acid to form furo[3,4-b]pyridine-5,7-dione (1); the resulting compound was heated with urea to form 5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione (2). After that, it was treated with potassium hydroxide to give potassium 5,7-dioxo-5,7-dihydropyrrolo[3,4-b]pyridin-6-dione, which was directly and easily converted to 6-(2-([1,1'-biphenyl]-4-yl)-2-oxoethyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione (3) by the reaction with 1-([1,1'-biphenyl]-4-yl)-2-bromoethan-1-one. Finally, the resultant compound reacted with substituted aniline to give imines (4, 5). Secondly the quinolinic acid converted to 4-(5,7-dioxo-5,7-dihydro-6H-pyrrolo[3,4-b] pyridin-6-yl) benzenesulfonyl chloride according to our previous work, then treated with p-hydroxy acetophenone or p-hydroxy benzaldehyde to form 4-substituted bezyloxy 4-(5,7-dioxo-5,7-dihydro-6H-pyrrolo[3,4-b] pyridine-6-yl) benzenesulfonate (6, 7), which were finally treated with substituted aniline to form new substituted imines (8–12).","PeriodicalId":35894,"journal":{"name":"Ecletica Quimica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75479227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Social media-based learning in Chemistry learning: A review 基于社交媒体的化学学习:综述

Ecletica Quimica Pub Date : 2023-04-01 DOI: 10.26850/1678-4618eqj.v48.2.2023.p17-21

H. Widarti, T. Sriwahyuni, Deni Ainur Rokhim, Afis Baghiz Syafrudin

引用次数: 0

Synthesis, structural and spectroscopic properties of Co(II), Ni(II) and Cu(II) complexes with 2-((2-chlorobenzylidene)amino) acetohydrazide hydrate and their Antimicrobial and antioxidant activities Co(II)、Ni(II)和Cu(II)与2-((2-氯苄二胺)氨基乙酰肼配合物的合成、结构和光谱性质及其抗菌和抗氧化活性

Ecletica Quimica Pub Date : 2023-04-01 DOI: 10.26850/1678-4618eqj.v48.2.2023.p66-82

F. Al-Azab, Y. Jamil, A. A. Al-Gaadbi

{"title":"Synthesis, structural and spectroscopic properties of Co(II), Ni(II) and Cu(II) complexes with 2-((2-chlorobenzylidene)amino) acetohydrazide hydrate and their Antimicrobial and antioxidant activities","authors":"F. Al-Azab, Y. Jamil, A. A. Al-Gaadbi","doi":"10.26850/1678-4618eqj.v48.2.2023.p66-82","DOIUrl":"https://doi.org/10.26850/1678-4618eqj.v48.2.2023.p66-82","url":null,"abstract":"The current study was purposed to prepare Co(II), Ni(II) and Cu(II) complexes with the ligands derived from 2-chlorobenzaldehyde, glycine and hydrazine hydrate. The obtained compounds were characterized by different physicochemical studies such as elemental analysis, atomic absorption, molar ratio analysis, electronic absorption (UV-Vis spectroscopy), magnetic properties, FTIR spectroscopy, 1H�NMR, 13C-NMR, conductance measurements and XRD. Antimicrobial and antioxidant activities were also calculated. The antibacterial activity was evaluated by the diffusion method against two Gram-positive and two Gram-negative bacteria, while antifungal activity was assessed against two fungal strains by using the agar method. The ligand with Schiff base and hydrazide groups and its complexes showed better biological activity. The results showed that the most metal complexes have much higher antibacterial and antifungal activity compared to the parent ligand. The antioxidant activity of 3.7453 mg of the ligand exhibited excellent activity as the activity of 1 mg of ascorbic acid which is used as a standard antioxidant.","PeriodicalId":35894,"journal":{"name":"Ecletica Quimica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80216160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of dopamine using glassy carbon electrodes modified with AgNPs synthetized with Monteverdia ilicifolia extract 用蒙太子提取物合成的AgNPs修饰玻碳电极检测多巴胺

Ecletica Quimica Pub Date : 2023-04-01 DOI: 10.26850/1678-4618eqj.v48.2.2023.p35-48

引用次数: 0

Second-generation ethanol: concept, production and challenges 第二代乙醇:概念、生产和挑战

Ecletica Quimica Pub Date : 2023-04-01 DOI: 10.26850/1678-4618eqj.v48.2.2023.p22-34

Pedro Vinicius Costa Medeiros, Paulo Henrique Medeiros Theophilo, G. S. Lopes, L. P. Ribeiro

引用次数: 1