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Japanese Journal of Gastroenterology最新文献

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[BRAF V600E-positive intrahepatic cholangiocarcinoma with suspected malignant transformation of the bile duct adenoma:a case report]. [BRAF v600e阳性肝内胆管癌合并胆管腺瘤疑似恶性转化1例]。
Japanese Journal of Gastroenterology Pub Date : 2025-01-01 DOI: 10.11405/nisshoshi.122.288
Masayuki Miyazaki, Keisuke Sakaguchi, Yuichi Tachibana, Akihiro Ueda, Seiya Kato, Osamu Nakashima, Tetsuro Akashi
{"title":"[BRAF V600E-positive intrahepatic cholangiocarcinoma with suspected malignant transformation of the bile duct adenoma:a case report].","authors":"Masayuki Miyazaki, Keisuke Sakaguchi, Yuichi Tachibana, Akihiro Ueda, Seiya Kato, Osamu Nakashima, Tetsuro Akashi","doi":"10.11405/nisshoshi.122.288","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.288","url":null,"abstract":"<p><p>A 69-year-old woman was diagnosed with extrahepatic portal vein occlusion and liver cirrhosis. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a ring-enhanced liver tumor. A liver tumor biopsy detected small bile duct proliferation without atypia and a map-like pattern on immunostaining for glutamine synthetase, resulting in a focal nodular hyperplasia diagnosis. CT after 4 years revealed the increased liver tumor. The patient was suspected of intrahepatic cholangiocarcinoma based on MRI findings. A liver tumor biopsy was re-conducted, and the patient was diagnosed with intrahepatic cholangiocarcinoma (small duct type), which was positive for BRAF V600E on immunostaining. We re-investigated the initial liver tumor biopsy tissue and diagnosed the BRAF V600E-positive bile duct adenoma, indicating a malignant transformation of the bile duct adenoma to an intrahepatic cholangiocarcinoma.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 4","pages":"288-296"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Crohn's disease complicated with squamous cell carcinoma originating from an enterocutaneous fistula:a case report]. [克罗恩病并发肠表皮瘘源性鳞状细胞癌1例]。
Japanese Journal of Gastroenterology Pub Date : 2025-01-01 DOI: 10.11405/nisshoshi.122.51
Ayako Komatsu, Kazutaka Koganei, Kenji Tatsumi, Hirosuke Kuroki, Nao Obara, Sayumi Saito, Akira Sugita, Hiroyuki Hayashi
{"title":"[Crohn's disease complicated with squamous cell carcinoma originating from an enterocutaneous fistula:a case report].","authors":"Ayako Komatsu, Kazutaka Koganei, Kenji Tatsumi, Hirosuke Kuroki, Nao Obara, Sayumi Saito, Akira Sugita, Hiroyuki Hayashi","doi":"10.11405/nisshoshi.122.51","DOIUrl":"10.11405/nisshoshi.122.51","url":null,"abstract":"<p><p>This case report describes Crohn's disease complicated by squamous cell carcinoma in an enterocutaneous fistula. A 48-year-old male patient was diagnosed with Crohn's disease 24 years ago and has undergone five surgical operations. An enterocutaneous fistula originated from the midline abdominal wound 11 years after the onset. Azathioprine was initiated instead of surgery due to frequent recurrence of the fistula and his short residual small intestine (approximately 170cm). We followed him every 3 months and continued prescribing azathioprine as his fistula secretions decreased and became manageable. He noticed a mass at the same site 13 years after the appearance of the enterocutaneous fistula which was diagnosed as squamous cell carcinoma through biopsy. The tumor was markedly reduced after preoperative chemoradiotherapy. We resected the affected intestinal tract and abdominal wall associated with the enterocutaneous fistula, and he acheived a pathological complete response. Squamous cell carcinoma originating from an enterocutaneous fistula in Crohn's disease is rare;however, long-standing inflammatory lesions should be carefully monitored for carcinogenesis.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 1","pages":"51-58"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Current status of intestinal transplantation]. [肠移植的现状]。
Japanese Journal of Gastroenterology Pub Date : 2025-01-01 DOI: 10.11405/nisshoshi.122.189
Takehisa Ueno
{"title":"[Current status of intestinal transplantation].","authors":"Takehisa Ueno","doi":"10.11405/nisshoshi.122.189","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.189","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 3","pages":"189-195"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hepatocellular carcinoma developing autoimmune hemolytic anemia after atezolizumab and bevacizumab combination therapy, transitioning to second-line treatment following improvement:a case report]. [肝细胞癌在阿特唑单抗和贝伐单抗联合治疗后发生自身免疫性溶血性贫血，改善后过渡到二线治疗：1例报告]。
Japanese Journal of Gastroenterology Pub Date : 2025-01-01 DOI: 10.11405/nisshoshi.122.138
Masayoshi Ko, Kota Fujimaki, Shohei Igarashi, Takato Maeda, Koji Shimaya, Norihiro Hanabata, Kosuke Kanazawa, Hiroshi Numao, Masaki Munakata
{"title":"[Hepatocellular carcinoma developing autoimmune hemolytic anemia after atezolizumab and bevacizumab combination therapy, transitioning to second-line treatment following improvement:a case report].","authors":"Masayoshi Ko, Kota Fujimaki, Shohei Igarashi, Takato Maeda, Koji Shimaya, Norihiro Hanabata, Kosuke Kanazawa, Hiroshi Numao, Masaki Munakata","doi":"10.11405/nisshoshi.122.138","DOIUrl":"10.11405/nisshoshi.122.138","url":null,"abstract":"<p><p>Atezolizumab and bevacizumab combination therapy was initiated in a 71-year-old female patient with unresectable hepatocellular carcinoma. Severe anemia, which was managed with blood transfusion and demonstrated improvement, was observed after the treatment. However, anemia subsequently reoccurred, accompanied by signs of hemolysis. The condition was diagnosed as autoimmune hemolytic anemia due to atezolizumab. Steroid therapy exhibited improvement, and second-line treatment with lenvatinib was successfully initiated. The possibility of autoimmune hemolytic anemia should be considered when anemia is observed during immunotherapy for hepatocellular carcinoma.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 2","pages":"138-147"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Debrief of the 66th Annual Meeting of the Japanese Society of Gastroenterology]. [第66届日本胃肠病学会年会报告]。
Japanese Journal of Gastroenterology Pub Date : 2025-01-01 DOI: 10.11405/nisshoshi.122.381
Naoya Sakamoto
{"title":"[Debrief of the 66th Annual Meeting of the Japanese Society of Gastroenterology].","authors":"Naoya Sakamoto","doi":"10.11405/nisshoshi.122.381","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.381","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 6","pages":"381-384"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Diagnosis of functional dyspepsia]. 功能性消化不良的诊断。
Japanese Journal of Gastroenterology Pub Date : 2025-01-01 DOI: 10.11405/nisshoshi.122.402
Masafumi Wada, Yosuke Minoda, Eikichi Ihara
{"title":"[Diagnosis of functional dyspepsia].","authors":"Masafumi Wada, Yosuke Minoda, Eikichi Ihara","doi":"10.11405/nisshoshi.122.402","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.402","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 6","pages":"402-408"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment of functional dyspepsia -psychological approach]. 功能性消化不良的治疗——心理学方法。
Japanese Journal of Gastroenterology Pub Date : 2025-01-01 DOI: 10.11405/nisshoshi.122.418
Ayumu Tateno, Kohei Handa
{"title":"[Treatment of functional dyspepsia -psychological approach].","authors":"Ayumu Tateno, Kohei Handa","doi":"10.11405/nisshoshi.122.418","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.418","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 6","pages":"418-424"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pathogenesis of functional dyspepsia]. [功能性消化不良的发病机制]。
Japanese Journal of Gastroenterology Pub Date : 2025-01-01 DOI: 10.11405/nisshoshi.122.394
Hidekazu Suzuki
{"title":"[Pathogenesis of functional dyspepsia].","authors":"Hidekazu Suzuki","doi":"10.11405/nisshoshi.122.394","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.394","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 6","pages":"394-401"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment of ulcerative colitis in the era of multiple option:optimization of conventional therapy now once again]. 【多选择时代溃疡性结肠炎的治疗：再一次优化现在的常规疗法】。
Japanese Journal of Gastroenterology Pub Date : 2025-01-01 DOI: 10.11405/nisshoshi.122.469
Kenji Watanabe, Yusuke Takashima, Saeko Takahashi
{"title":"[Treatment of ulcerative colitis in the era of multiple option:optimization of conventional therapy now once again].","authors":"Kenji Watanabe, Yusuke Takashima, Saeko Takahashi","doi":"10.11405/nisshoshi.122.469","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.469","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 7","pages":"469-478"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Strategies and perspectives for addressing immune checkpoint inhibitor resistance in the era of combination immunotherapy for advanced hepatocellular carcinoma]. [晚期肝细胞癌联合免疫疗法时代应对免疫检查点抑制剂耐药性的策略和前景]。
Japanese Journal of Gastroenterology Pub Date : 2024-01-01 DOI: 10.11405/nisshoshi.121.737
Sadahisa Ogasawara, Naoya Kanogawa, Naoya Kato
{"title":"[Strategies and perspectives for addressing immune checkpoint inhibitor resistance in the era of combination immunotherapy for advanced hepatocellular carcinoma].","authors":"Sadahisa Ogasawara, Naoya Kanogawa, Naoya Kato","doi":"10.11405/nisshoshi.121.737","DOIUrl":"10.11405/nisshoshi.121.737","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"121 9","pages":"737-744"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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