Malaysian Journal of Paediatrics and Child Health最新文献_第3页

Mental Well-being in Adolescents with Diabetes during the COVID-19 Pandemic and Impact on Glycaemic Control COVID-19大流行期间青少年糖尿病患者的心理健康状况及其对血糖控制的影响

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-05-09 DOI: 10.51407/mjpch.v29i2.250

H. Cheng, J. Wong, Nalini M. Selveindran, L. Mohamed Nor, J. Y. Hong

{"title":"Mental Well-being in Adolescents with Diabetes during the COVID-19 Pandemic and Impact on Glycaemic Control","authors":"H. Cheng, J. Wong, Nalini M. Selveindran, L. Mohamed Nor, J. Y. Hong","doi":"10.51407/mjpch.v29i2.250","DOIUrl":"https://doi.org/10.51407/mjpch.v29i2.250","url":null,"abstract":"Introduction: Psychological distress was experienced by millions of people affected by the coronavirus (COVID-19) pandemic, particularly adolescents with diabetes. Method: A cross-sectional study was conducted among adolescents with type 1 (T1DM) and type 2 diabetes mellitus (T2DM) aged 10-18 years during the nationwide lockdown from June-December 2020 in Malaysia to assess the impact of COVID-19 towards their mental health. Eighty-seven participants were recruited and interviewed regarding their lifestyle changes, followed by the administration of the Depression, Anxiety and Stress Scale (DASS-21). Results: Fifty-eight patients with T1DM (30 males, 51.7%) and 29 patients with T2DM (9 males, 31%) participated in the study. The incidence of depressive, anxiety and stress symptoms were detected in 34%, 41% and 26% respectively of diabetic adolescents with no significant difference between T1DM and T2DM patients. Male gender, T2DM, puberty and the presence of anxiety symptoms were associated with deterioration in glycaemic control post-lockdown. There was a deterioration in HbA1c among male and T2DM patients by 0.76% and 0.94% respectively (p-value 0.013, 0.004 respectively). An increment of HbA1c pre- and post-lockdown was observed in patients with anxiety symptoms (9.39 ± 0.49 vs 10.16 ± 0.54%, p-value 0.028). Patients who displayed stress symptoms showed improvement in their HbA1c (10.00 ± 0.57% vs 9.50 ± 0.063%, p-value 0.036). Conclusion: There is a high prevalence of psychological disturbance among diabetic adolescents during the COVID-19 pandemic, particularly the anxiety component related to poor glycaemic control. Follow-up psychological assessment and support must be given to these young diabetic patients.","PeriodicalId":356217,"journal":{"name":"Malaysian Journal of Paediatrics and Child Health","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117310408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research on children in the developing world. Quo Vadis? 对发展中国家儿童的研究。何去何从？

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-04-19 DOI: 10.51407/mjpch.v29i1.261

Fahisham Taib, H. Van Rostenberghe, N. Ramli, A. Husin, T. H. Sasongko, C. Torres

引用次数: 0

Arthritis as the Initial Presentation of a Child With Acute Lymphoblastic Leukemia 关节炎是儿童急性淋巴细胞白血病的初始表现

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-04-10 DOI: 10.51407/mjpch.v29i1.251

La Reinala Sangaran, Tang Swee Ping, Koay Beng Siang

引用次数: 0

Follicular Thyroid Carcinoma Presenting with A Hyperfunctioning Nodule in An Adolescent Girl 青春期少女甲状腺滤泡癌伴功能亢进结节

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-03-29 DOI: 10.51407/mjpch.v29i1.243

Shi-Hui Saw, J. Wong, H. Cheng, Nalini M. Selveindran, Jajnet Yeow Hua Hong

{"title":"Follicular Thyroid Carcinoma Presenting with A Hyperfunctioning Nodule in An Adolescent Girl","authors":"Shi-Hui Saw, J. Wong, H. Cheng, Nalini M. Selveindran, Jajnet Yeow Hua Hong","doi":"10.51407/mjpch.v29i1.243","DOIUrl":"https://doi.org/10.51407/mjpch.v29i1.243","url":null,"abstract":"\u0000\u0000\u0000\u0000Background: Follicular thyroid carcinoma is rare in young patients and further diagnostic challenge is added when it presents as a hyperfunctioning thyroid nodule. Case report: We described a 14-year-old girl who presented with thyrotoxicosis and a large goitre associated with compressive symptoms. Thyroid scintigraphy demonstrated a solitary autonomous hyperfunctioning thyroid nodule. FNAC examination was not suggestive of malignancy. Thyrotoxicosis was controlled with carbimazole and a hemithyroidectomy was done. Histopathological examination revealed minimally invasive follicular thyroid carcinoma, following then, complete thyroidectomy was done. Discussion: This patient’s risk factors of malignancy were her age (young), gender (female), large nodule size, progressive growth, and compressive symptoms. This case illustrates the limitation of FNAC to ascertain malignancy in patients with large AFTN as the initial FNAC report was consistent with a benign lesion. Surgical resection without prior FNAC should be considered for cases with hyperfunctioning thyroid nodule which then would allow timely histologic analysis and accurate diagnosis. Conclusion: Autonomous functioning nodules in children and adolescents warrant careful evaluation to exclude malignancy. Our case illustrated the challenges to discriminate between malignant and benign lesions preoperatively for children and adolescents who present with AFNT.\u0000\u0000\u0000\u0000","PeriodicalId":356217,"journal":{"name":"Malaysian Journal of Paediatrics and Child Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130829697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative Diagnostic Dilemma of Diaphragmatic Eventration 膈肌膨出的术前诊断困境

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-03-29 DOI: 10.51407/mjpch.v29i1.227

Muhammad Faeid Othman, Ahmad Zuhdi Mamat, Norsuhana Omar, M. S. Mohd Shah

{"title":"Preoperative Diagnostic Dilemma of Diaphragmatic Eventration","authors":"Muhammad Faeid Othman, Ahmad Zuhdi Mamat, Norsuhana Omar, M. S. Mohd Shah","doi":"10.51407/mjpch.v29i1.227","DOIUrl":"https://doi.org/10.51407/mjpch.v29i1.227","url":null,"abstract":"\u0000\u0000\u0000\u0000Background: Diaphragmatic eventration is an abnormal elevation of the dome of the diaphragm into the thoracic cavity. Neonatal respiratory distress is the most common clinical presentation of diaphragmatic eventration. Direct abdominal organ compression on the lung or lung hypoplasia is the cause of this symptom. Preoperative radiological imaging is important to diagnose diaphragmatic eventration. Chest radiographs, ultrasound, CT scans and MRI can be used to evaluate the anatomy of the diaphragm. In complicated condition, video-assisted thoracoscopy (VATS) play a role as a diagnostic and therapeutic tool to diagnose and manage diaphragmatic eventration. Case presentation: We presented a case of a full-term unfortunate baby delivered via emergency lower segment caesarean section due to bleeding of the placenta previa type III. Immediately post-delivery, the patient had respiratory distress with an episode of desaturation. CT scan showed a focal right hemi-diaphragmatic bulge with liver tissue within. Video-assisted thoracoscopy (VATS) was performed and the diagnosis of right diaphragmatic eventration had been established. Diaphragmatic plication was done via a VATS-assisted thoracotomy approach. Conclusion: Video-assisted thoracoscopy (VATS) plays a role as a diagnostic tool and even as a therapeutic tool to diagnose and manage diaphragmatic eventration. The capability of VATS to provide direct visualization intrathoracically has a great advantage in managing a such case.\u0000\u0000\u0000\u0000","PeriodicalId":356217,"journal":{"name":"Malaysian Journal of Paediatrics and Child Health","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127296695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Pair of Siblings with Vitamin D Dependent Rickets (VDDR) Type 1A: More Than Dairy and Sunshine 一对患有维生素D依赖性佝偻病(VDDR) 1A型的兄弟姐妹:不仅仅是乳制品和阳光

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-03-19 DOI: 10.51407/mjpch.v29i1.230

Bee Shuang Lee, J. Wong

引用次数: 0

Closure of Hemodynamically Significant Patent Ductus Arteriosus and Factors Associated with Treatment Failure with Paracetamol 对乙酰氨基酚治疗失败的相关因素及血流动力学意义显著的动脉导管未闭闭合

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-01-04 DOI: 10.51407/mjpch.v28i2.197

Mohd Nizam Mat Bah, E. Alias, Chong Winnie, Mohd Hanafi Sapian, N. Abdullah

{"title":"Closure of Hemodynamically Significant Patent Ductus Arteriosus and Factors Associated with Treatment Failure with Paracetamol","authors":"Mohd Nizam Mat Bah, E. Alias, Chong Winnie, Mohd Hanafi Sapian, N. Abdullah","doi":"10.51407/mjpch.v28i2.197","DOIUrl":"https://doi.org/10.51407/mjpch.v28i2.197","url":null,"abstract":"\u0000\u0000\u0000\u0000Objective: There is a scarcity of data on the factors associated with nonresponders to paracetamol for closure of hemodynamically significant patent ductus arteriosus (hsPDA). This study aims to determine the failure rate and to identify factors associated with nonresponders to acetaminophen to close hsPDA. Methods: This retrospective, observational cohort study involved all inborn delivered at ≤ 32 weeks and birth weight of < 1.5 kg who had hsPDA. A multivariable logistic regression model was used to identify factors associated with nonresponders to paracetamol. Results: There were 137 hsPDA patients with a mean birth weight, gestational age, and age of diagnosis of 1027.9 ± 209.2 g, 28.1 ± 2.1 weeks, and 12.0 ± 7.2 days. The mean dimension of hsPDA, left atrium to the aorta, and PDA to left pulmonary artery ratio was 3.03 ± 0.64 mm, 1.94 ± 0.41, and 1.02 ± 0.17, respectively. The nonresponders to paracetamol was 18.2% (95% confidence interval [CI]: 12.4-25.9) and was significantly associated with bronchopulmonary dysplasia (BPD) (15/25 vs. 16/112, p<0.001) and interventricular hemorrhage (IVH) (13/25 vs. 31/112, p=0.02). Factors associated with nonresponders were a PDA to left pulmonary artery ratio (LPA) > 1.0 and ventilation at diagnosis with adjusted odds ratios of 6.69 and 4.17, respectively. Conclusions: One in five infants with hsPDA did not respond to treatment and were significantly associated with BPD and IVH. Invasive ventilation at diagnosis and a PDA to LPA ratio of > 1 were associated with treatment failure. Hence, different strategies are needed in this group of hsPDA.\u0000\u0000\u0000\u0000","PeriodicalId":356217,"journal":{"name":"Malaysian Journal of Paediatrics and Child Health","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121294546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum Cardiac Troponin I As a Diagnostic Marker of Myocardial Injury Among Human Immunodeficiency Virus Infected Children in Ilorin Kwara State Nigeria 血清心肌肌钙蛋白I作为尼日利亚伊洛林夸拉州人类免疫缺陷病毒感染儿童心肌损伤的诊断标志物

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-01-01 DOI: 10.51407/mjpch.v28i2.178

S. Bello, M. Abdulkadir, Taofik O Ogunkunle, G. Popoola, S. Ernest

{"title":"Serum Cardiac Troponin I As a Diagnostic Marker of Myocardial Injury Among Human Immunodeficiency Virus Infected Children in Ilorin Kwara State Nigeria","authors":"S. Bello, M. Abdulkadir, Taofik O Ogunkunle, G. Popoola, S. Ernest","doi":"10.51407/mjpch.v28i2.178","DOIUrl":"https://doi.org/10.51407/mjpch.v28i2.178","url":null,"abstract":"\u0000\u0000\u0000\u0000Background: Cardiac Troponin I (cTnI) is a unique marker of myocardial injury. It is the most sensitive and specific of the cardiac markers. Studies have shown its elevation among Human Immunodeficiency Virus (HIV) infected subjects. Most of these were in adults hence we determined the use of cTnI as a marker of myocardial injury among HIV subjects. Methods: The study was a comparative cross-sectional study among 100 HIV - infected children aged 2 – 14 years and equal age-matched HIV-uninfected controls. Recruitment was through the Paediatric HIV and outpatient clinics of the hospital respectively. Both groups had serum cTnI assay (normal is <0.1μ/L) over four months period. Data analysis was done using the SPSS® v 20. Normally distributed data had mean standard deviation while not normally distributed data had a median with an interquartile range determined. The diagnostic performance of cTnI was determined using the Receiver Operating Characteristics curve. Significant p is < 0.05. Results: A total of 200 (subjects and controls) were studied. The mean age of participants was 9.42 years. There was a significant difference in the median (IQR) cTnI of HIV-infected subjects [73.8 (51.8 – 149.1)] compared with HIV uninfected controls [25.0 (13.3 – 51.4)] p < 0.001. The prevalence of myocardial injury among subjects was 48% compared with 8% among controls, also statistically significant (p < 0.001). Serum cTnI has 91.3% and 88.9% sensitivity and specificity respectively. Conclusions: The prevalence of myocardial injury was high in HIV - infected children. Serum cTnI is a reliable predictive marker of myocardial injury.\u0000\u0000\u0000\u0000","PeriodicalId":356217,"journal":{"name":"Malaysian Journal of Paediatrics and Child Health","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117234186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and Validation of Brief Education Program on Learning Disability in Children for Pre-School Teachers 幼儿教师学习障碍简要教育计划的开发与验证

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-01-01 DOI: 10.51407/mjpch.v28i2.223

Aznita Iryany Mohd Noor, A. Othman, Fahisham Taib, Mohd Zulkifli Abd Rahim, Aswatı Hamzah, Azriani Ab Rahman, I. J. Abd Hamid

{"title":"Development and Validation of Brief Education Program on Learning Disability in Children for Pre-School Teachers","authors":"Aznita Iryany Mohd Noor, A. Othman, Fahisham Taib, Mohd Zulkifli Abd Rahim, Aswatı Hamzah, Azriani Ab Rahman, I. J. Abd Hamid","doi":"10.51407/mjpch.v28i2.223","DOIUrl":"https://doi.org/10.51407/mjpch.v28i2.223","url":null,"abstract":"\u0000\u0000\u0000\u0000Introduction: Learning disability (LD) in children is very common, yet it is often missed by many educators. Aim: We developed a brief education program on learning disability (LD) in children and validated its corresponding assessment tool (Knowledge and Attitude on Learning Disability Questionnaire (KALDQ) for pre-school teachers in Malaysia. Methods: Based on an extensive review, the essential educational components of a program for LD in children and relevant items for KALDQ were identified, from which a brief health educational program was designed. The face and content validity of the tools were established via expert evaluation. A subsequent pilot study was held on 57 pre-school teachers (N=57) to evaluate the feasibility of the program and to establish the construct validity and reliability of the newly developed KALDQ. Results: A 10-hour interactive health education program comprises of 4 sessions to orientate pre-school teachers on LD in children and direct them towards medical referral and rehabilitations services, as appropriate, was developed. The face and content validity for both the program and KALDQ were satisfactory. Exploratory factor analysis performed on the original 65-items questionnaire. The final KALDQ consisted of 34 knowledge-domain and 14 attitude-domain items. The reliability of the two domains was satisfactory (Knowledge-domain α=0.83, Attitude-domain α=0.60). Discussion: This study developed a brief education program on LD in children and its corresponding assessment tool. KALDQ is valid and reliable to be used to assess the effects of this newly developed program on participants’ knowledge and attitude after attending the program.\u0000\u0000\u0000\u0000","PeriodicalId":356217,"journal":{"name":"Malaysian Journal of Paediatrics and Child Health","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115774059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing Short-Term Effects of Umbilical Artery Catheter (UAC) Tip Position in Neonates: A Randomized Control Trial 比较新生儿脐动脉导管(UAC)尖端位置的短期效果:一项随机对照试验

Malaysian Journal of Paediatrics and Child Health Pub Date : 2023-01-01 DOI: 10.51407/mjpch.v28i2.222

Sitti Sulhoon Mohamed, Fahisham Taib, N. R. Ibrahim, H. Van Rostenberghe, N. Ramli

{"title":"Comparing Short-Term Effects of Umbilical Artery Catheter (UAC) Tip Position in Neonates: A Randomized Control Trial","authors":"Sitti Sulhoon Mohamed, Fahisham Taib, N. R. Ibrahim, H. Van Rostenberghe, N. Ramli","doi":"10.51407/mjpch.v28i2.222","DOIUrl":"https://doi.org/10.51407/mjpch.v28i2.222","url":null,"abstract":"\u0000\u0000\u0000\u0000Introduction: The latest Cochrane review supported high-position umbilical artery catheters (UAC) as it led to fewer complications and reduced the need for replacement or re-insertion of the catheters. However, the studies included were dated more than three decades ago. Objectives: To determine the safety (short-term complications) of UAC in the newborn at two different positions. Methods: A randomized control trial was performed from March 2012 to August 2013, among the newborns requiring UAC insertion in Neonatal Intensive Care, at Hospital Universiti Sains Malaysia. Patients were randomly assigned to either high or low UAC positions using block randomization. Outcomes: The primary outcomes were the incidence of aortic thrombosis, intraventricular haemorrhage (IVH), necrotising enterocolitis, hypertension, haematuria and feeding intolerance. The secondary outcome was to compare the incidence of short-term outcomes of UAC position to gestational age and birth weight. Results: One hundred and seventy-eight patients were included (89 per study arm). The mean gestational age was 34 weeks with a mean birth weight of 2.31 kg. There were no significant differences between the two groups in terms of baseline data. The overall incidence of complications was 20 (23%) in the low position and 18 (20%) in the high position group UAC (p=0.76). The observed complications between the low and high position UAC group: IVH 6.7% vs. 9%, p=0.58; feeding intolerance 6.7% vs. 4%, p=0.51; hypertension 4% vs. 6%, p=0.51; peripheral ischemic 2% vs. 0%, p=0.25. Conclusion: This study showed that the rate of complications in the low UAC position was comparable with the high UAC position.\u0000 \u0000\u0000\u0000\u0000","PeriodicalId":356217,"journal":{"name":"Malaysian Journal of Paediatrics and Child Health","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122347944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0