{"title":"[A case of hyponatremia induced by the thiazide-like diuretic indapamide in an elderly woman].","authors":"Nobuya Nakaguki, Kei Sasaki, Yasuhiro Endo, Katsunori Ikewaki","doi":"10.3143/geriatrics.62.88","DOIUrl":"10.3143/geriatrics.62.88","url":null,"abstract":"<p><p>A 72-year-old woman with a history of hypertension who had already been taking calcium channel blockers and angiotensin II receptor blockers was prescribed additional indapamide (1 mg/day) due to inadequate blood pressure control. Two weeks later, she experienced loss of appetite and fatigue. Seeking medical attention, she was diagnosed with significant hyponatremia with a serum sodium level of 110 mEq/L at a local clinic, leading to her referral and subsequent admission to our department. Although her consciousness remained clear, laboratory findings revealed a serum sodium level of 116 mEq/L, blood urea nitrogen of 7 mg/dL, blood glucose of 96 mg/dL, and plasma osmolarity of 239.8 mOsm/kg·H<sub>2</sub>O, consistent with hypotonic hyponatremia induced by indapamide. Indapamide was discontinued and normal saline was administered. By the 6th day of hospitalization, her serum sodium level had improved to 130 mEq/L, and her symptoms had resolved.Thiazide-like diuretics can induce hyponatremia as a side effect with diverse symptoms and variable onset. However, in this case, hyponatremia was promptly detected shortly after the initiation of indapamide therapy, and no gastrointestinal symptoms other than anorexia were observed. When initiating thiazide-like diuretics, it is essential to be vigilant for hyponatremia and to provide appropriate medication guidance to patients in addition to monitoring their serum sodium levels.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"62 1","pages":"88-92"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effect of antihypertensive medication on systolic blood pressure variability during bathing in elderly people].","authors":"Tomoaki Suzuki, Shuichiro Watanabe","doi":"10.3143/geriatrics.62.42","DOIUrl":"10.3143/geriatrics.62.42","url":null,"abstract":"<p><strong>Aim: </strong>The present study clarified the relationship between the temperature of bath water, the presence of systolic hypertension, the presence of antihypertensive medication, and the pulse rate during bathing, focusing on the variation of systolic blood pressure.</p><p><strong>Methods: </strong>Twenty community-dwelling men 61 to 87 years old were included in the study. The subjects were randomly divided into 2 groups, based on bath temperature 39°C and 41°C. They were then given a full-body bath for 10 minutes.</p><p><strong>Results: </strong>The variables significantly related to the change in systolic blood pressure from 2 to 8 minutes after bathing were the presence or absence of antihypertensive medication, and the interaction between the presence of antihypertensive medication and the change in pulse rate from 2 to 8 minutes after bathing.</p><p><strong>Conclusions: </strong>Antihypertensive medication had a favorable effect on the reduction of systolic blood pressure during bathing.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"62 1","pages":"42-49"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ikki Yoshida, Yohei Sawaya, Yukinobu Hiiragi, Shunsuke Kikuchi, Tomohiko Urano
{"title":"[Preoperative frailty in patients undergoing total knee or hip arthroplasty affects FIM scores at one week postoperatively].","authors":"Ikki Yoshida, Yohei Sawaya, Yukinobu Hiiragi, Shunsuke Kikuchi, Tomohiko Urano","doi":"10.3143/geriatrics.62.178","DOIUrl":"https://doi.org/10.3143/geriatrics.62.178","url":null,"abstract":"<p><strong>Aim: </strong>Very few reports have investigated the association between frailty and postoperative outcomes in total knee arthroplasty (TKA) and total hip arthroplasty (THA), making the accumulation of evidence an urgent task. This study aimed to clarify the effect of preoperative frailty on short-term postoperative outcomes in patients undergoing TKA/THA.</p><p><strong>Methods: </strong>This prospective cohort study, conducted from December 2023 to September 2024, included 19 patients (mean age±standard deviation, 73.8±7.2 years) scheduled for TKA/THA. Frailty was assessed preoperatively using the Questionnaire for Medical Checkup of Old-Old (QMCOO) and the Japanese version of the Cardiovascular Health Study (J-CHS) criteria, along with the Functional Independence Measure (FIM). FIM scores were also evaluated one week postoperatively. Postoperative FIM scores were compared based on frailty status.</p><p><strong>Results: </strong>Of the 19 patients, 6 (31.6%) were classified as having frailty based on the QMCOO (score≥5) and 7 (36.8%) met the frailty criteria according to the J-CHS. With regard to the preoperative to postoperative FIM score change, the QMCOO≥5 group showed a significantly larger decline (-23.2±10.1 points, [median, -19.5]) in comparison to the QMCOO<5 group (-13.8±4.7 points, [median, -15.0]) (p=0.029). Similarly, patients classified as having frailty according to the J-CHS (-23.1±8.8 points, [median, -20.0]) experienced a greater FIM decline than the non-frailty (-13.1±4.4 points, [median, -13.5]) (p=0.004). Moreover, patients classified as frail according to J-CHS had lower FIM scores at one week postoperatively (p<0.001), with a significantly higher proportion of patients scoring < 110 points (p=0.017).</p><p><strong>Conclusions: </strong>Preoperative frailty may negatively affect short-term postoperative outcomes after TKA/THA.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"62 2","pages":"178-186"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[CGA tools and its usefulness].","authors":"","doi":"10.3143/geriatrics.62.17","DOIUrl":"https://doi.org/10.3143/geriatrics.62.17","url":null,"abstract":"","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"62 1","pages":"17-20"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Screening and Management of Dementia Using CGA].","authors":"","doi":"10.3143/geriatrics.62.21","DOIUrl":"https://doi.org/10.3143/geriatrics.62.21","url":null,"abstract":"","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"62 1","pages":"21-27"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Person-centered care-based digital transformation education program for elderly dementia patients with delirium: a comparison of the effect on nurses and doctors].","authors":"Mizue Suzuki, Tomotaka Ito, Keigo Inagaki, Soichiro Mimuro, Miyae Yamakawa, Keigo Takiue, Keisuke Sawaki, Yusuke Komatsu, Masayo Uchiyama, Chieko Kawashima, Kaoru Yamazaki, Masako Satoh, Satoshi Isogai","doi":"10.3143/geriatrics.62.59","DOIUrl":"10.3143/geriatrics.62.59","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to develop an educational program for doctors and nurses who treat and care for older adults with dementia and delirium, based on a person-centered care program, utilizing virtual reality (VR) and augmented reality (AR).</p><p><strong>Methods: </strong>A VR/AR-based program was implemented from February 16 to June 10, 2023, and participants were asked to complete questionnaires before the intervention, immediately after, and three months later.</p><p><strong>Results: </strong>This study included 74 participants, including 61 nurses (84.2%) and 13 doctors (17.6%). Confidence in delirium care significantly increased for both nurses and doctors immediately after the intervention and one month later relative to baseline. However, knowledge of delirium did not show significant improvement in either nurses or doctors. In the Approaches to Dementia Questionnaire, nurses showed significant improvement in the domain of \"personhood\" and their total score after one month relative to baseline. The total score of doctors only improved immediately after the intervention relative to the baseline score. In the Team Approach Assessment Scale-Revised, nurses showed significant improvement in the domain of \"clarification of goals and roles\" and the total score of nurses at one month relative to baseline, while physicians showed no significant improvement.</p><p><strong>Conclusion: </strong>The program using VR/AR to experience the viewpoints of elderly individuals with dementia and the experiences of multiple professions in this study significantly improved nurses' practice and awareness of person-centered care for older adults with dementia, and nurses' and physicians' confidence in their treatment and care for delirium. Moreover, the study highlights the necessity of incorporating interventions that draw upon the expertise of various professions within dementia care programs to promote multidisciplinary collaboration.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"62 1","pages":"59-69"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Advanced care planning in kidney replacement therapy for elderly CKD patients].","authors":"","doi":"10.3143/geriatrics.62.145","DOIUrl":"https://doi.org/10.3143/geriatrics.62.145","url":null,"abstract":"","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"62 2","pages":"145-149"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sora Shimamura, Ryo Katayose, Mika Okura, Saki Tanaka, Hidenori Arai, Mihoko Ogita
{"title":"[Association between the duration of residence and cognitive impairment in community-dwelling older Japanese adults: A four-year prospective longitudinal study].","authors":"Sora Shimamura, Ryo Katayose, Mika Okura, Saki Tanaka, Hidenori Arai, Mihoko Ogita","doi":"10.3143/geriatrics.62.150","DOIUrl":"https://doi.org/10.3143/geriatrics.62.150","url":null,"abstract":"<p><strong>Aim: </strong>Previous studies have reported that migration is associated with cognitive impairment, and that disconnections from local communities affect cognitive function. This study examined the association between the duration of residence and cognitive impairment.</p><p><strong>Methods: </strong>The survey consisted of designed a 4-year longitudinal study that was conducted in 2013 and 2017 in Kami Town, Hyogo Prefecture, Japan. Among the 3,605 completed questionnaires, 2,051 were selected, excluding those with cognitive impairment in 2013 and/or missing data. The duration of residence until 2013 was categorized as ≤ 5 or ≥ 6 years. Cognitive impairment was defined as a person who was determined to have cognitive decline on the Kihon checklist. Odds ratios (ORs) and 95% confidence intervals (CIs) for cognitive impairment were calculated according to sex and participation in community activities using multivariate logistic regression analysis after adjusting for age, mobility impairment, and depression.</p><p><strong>Results: </strong>Of the 2,051 respondents, there were 1,299 women (63.3%; mean age, 74.1±6.2 years old) and the prevalence of cognitive impairment was 514 (25.1%). Multivariate logistic regression showed that women with a residence duration ≤ 5 years were more likely to have an impaired cognitive function than a residence duration ≥ 6 years; the adjusted ORs (95%CIs) were 1.65 (0.55-4.91) in those who participated in community activities and 3.86 (1.33-11.24) in those who did not. In contrast, no significant association was observed among the men.</p><p><strong>Conclusion: </strong>This finding suggests that among community-dwelling older adults, women who have lived in the community for less than 5 years and who do not participate in community activities may be at increased risk of deterioration in the cognitive domains of the KCL after 4 years.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"62 2","pages":"150-158"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Association between suspected dementia and transition from diaper use in inpatients undergoing convalescent rehabilitation: A multicenter retrospective cohort study].","authors":"Naoyuki Tsue, Kotomi Sakai, Shota Hamada, Nobuo Sakata","doi":"10.3143/geriatrics.62.212","DOIUrl":"10.3143/geriatrics.62.212","url":null,"abstract":"<p><strong>Aim: </strong>The cognitive function is important for activities of daily living (ADL). However, few studies have examined the association between the cognitive function and diaper use in patients admitted to convalescent rehabilitation wards. This study aimed to identify the association between suspected dementia and the transition from diaper use in patients admitted to convalescent rehabilitation wards.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of patients admitted to convalescent rehabilitation wards across nine hospitals, all of whom used tape diapers. Suspected dementia was defined as a score of ≤20 on the revised Hasegawa Simplified Intelligence Scale, and transition from diaper use was defined as the use of rehabilitation or cloth pants. A binomial logistic regression analysis was used to examine this association between suspected dementia and the transition from diaper use.</p><p><strong>Results: </strong>We included 100 patients with cerebrovascular disease (male, 52%; median age, 81 years; prevalence of suspected dementia, 65%), 112 patients with musculoskeletal disease (male, 22.3%; median age, 87 years; prevalence of suspected dementia, 40.2%), and 52 patients with disuse syndrome (male, 46.2%; median age, 85 years; prevalence of suspected dementia, 75%). Suspected dementia was significantly associated with the transition from diaper use in patients with cerebrovascular disease (adjusted odds ratio[aOR], 0.30; 95% confidence interval[CI], 0.11-0.86; p=0.024), musculoskeletal disease (aOR, 0.15, 95% CI, 0.05-0.46; p<0.001), and disuse syndrome (aOR, 0.10; 95% CI, 0.01-0.79; p=0.029).</p><p><strong>Conclusions: </strong>Suspected dementia was negatively associated with transition from diaper use in patients admitted to convalescent rehabilitation wards. The assessment of suspected dementia may be useful in determining intervention policies for transitioning from diaper use.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"62 2","pages":"212-219"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}