Japanese Journal of Geriatrics最新文献

{"title":"[A case of elderly Parkinson's disease patient with thrombocytopenia due to hypothermia].","authors":"","doi":"10.3143/geriatrics.61.480","DOIUrl":"https://doi.org/10.3143/geriatrics.61.480","url":null,"abstract":"","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 4","pages":"480-482"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Decision-making support for people with dementia].","authors":"","doi":"10.3143/geriatrics.61.419","DOIUrl":"https://doi.org/10.3143/geriatrics.61.419","url":null,"abstract":"","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 4","pages":"419-423"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Undernutrition and sarcopenic obesity according to the GLIM criteria phenotype in elderly patients with diabetes].","authors":"Satoshi Ida, Kanako Imataka, Masaki Morii, Keitaro Katsuki, Kazuya Murata","doi":"10.3143/geriatrics.61.322","DOIUrl":"https://doi.org/10.3143/geriatrics.61.322","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the frequency of malnutrition and sarcopenic obesity in elderly patients with diabetes according to the Global Leadership Initiative on Malnutrition (GLIM) phenotypes.</p><p><strong>Methods: </strong>The subjects were outpatients with diabetes who were ≥65 years of age and were managed at Ise Red Cross Hospital. Undernutrition was assessed and categorized into the following GLIM criteria phenotypes: (1) no undernutrition, (2) undernutrition (weight loss or low body mass index [BMI]/no low appendicular skeletal muscle mass index [ASMI]), (3) undernutrition (no weight loss or no low BMI/low ASMI), and (4) undernutrition (weight loss or low BMI/low ASMI). Sarcopenia was diagnosed according to the definition of the Asian Working Group for Sarcopenia 2019, and obesity was diagnosed based on the body fat percentage.</p><p><strong>Results: </strong>In total, 490 patients were included in the analysis. The frequency of undernutrition was 29.0%, and the frequency of undernutrition according to the GLIM criteria phenotypes was as follows: weight loss or low BMI/no low ASMI group, 10.6%; no weight loss and no low BMI/low ASMI group, 9.8%; and weight loss or low BMI/low ASMI group, 8.6%. The frequency of sarcopenic obesity was 7.3%, with the majority of cases found in the no weight loss or no low BMI/low ASMI groups.</p><p><strong>Conclusion: </strong>The frequency of undernutrition and sarcopenic obesity in elderly patients with diabetes, according to the GLIM phenotypes, was revealed. It is important to pay attention not only to weight loss and low BMI, but also to undernutrition and sarcopenic obesity with reduced skeletal muscle mass when diagnosing undernutrition in elderly diabetic patients.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 3","pages":"322-328"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Examination of cases in which senility was determined to be the cause of death in community medicine].","authors":"Hideyuki Murakami","doi":"10.3143/geriatrics.61.329","DOIUrl":"https://doi.org/10.3143/geriatrics.61.329","url":null,"abstract":"<p><strong>Aim: </strong>In community medicine, there are many opportunities in which senility is noted as the cause of death. However, there are no clear criteria for diagnosing senility, and this decision is often left to the judgment of individual doctors. This study investigated the clinical characteristics of patients diagnosed with senility at our hospital.</p><p><strong>Methods: </strong>The subjects included 43 patients whose cause of death was listed as senility from among the death certificates of 282 patients prepared at our hospital. The survey items included age, sex, medical history, place of death, period from the day of explanation of the condition of senility to the date of death, BMI at the time of explanation, and blood sampling test.</p><p><strong>Results: </strong>The mean age of patients who died due to senility was 92.2±6.5 years old. The male to female ratio was 15: 28. The most common medical history was dementia (76.7%), followed by hypertension and orthopedic disease (74.4%), respiratory disease (66.7%), and heart disease and gastrointestinal disease (60.5%). The places of death were nursing homes and private homes, and hospitals. The overall average time from presentation until death occurred was 110.2 days. There were also considerable differences depending on the case. The average BMI was 19.7±3.0, and the blood sampling results showed that total protein and serum albumin levels were lower than the reference values.</p><p><strong>Conclusions: </strong>Although the diagnosis of senility is vague and unclear, it is important to explain such a diagnosis to the family at an appropriate time and to cooperate with multiple professionals in the treatment process.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 3","pages":"329-336"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Why does clinical ethics focus on \"Eating\" in elderly people? -to support the decision making by the vulnerable elderly].","authors":"","doi":"10.3143/geriatrics.61.280","DOIUrl":"https://doi.org/10.3143/geriatrics.61.280","url":null,"abstract":"","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 3","pages":"280-284"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Postnatal epigenome-mediated aging control and global trends].","authors":"Motoshi Hayano","doi":"10.3143/geriatrics.61.1","DOIUrl":"https://doi.org/10.3143/geriatrics.61.1","url":null,"abstract":"<p><p>The epigenome can adequately regulate the on/off states of genes in response to external environmental factors and stress. In recent years, it has been observed that the epigenome, which is modulated through DNA methylation, histone modifications, and chromatin remodeling, changes with age. Alterations in the epigenome lead to the loss of cell-specific epigenome/identity, which in turn triggers a decline in tissue function. In mammals, postnatal epigenomic variations are not only caused by metabolic diseases, such as diabetes or DNA damage, but also by social stress and infectious diseases. Unlike Genome-Wide Association Studies (GWAS), dynamically changing epigenomes, along with their cellular roles, need to be established as objective biomarkers in conjunction with various biological signals, such as walking speed, brain waves, and clinical data. The biological age/aging clock, determined by methylated DNA, has attracted attention, and calorie restriction not only slows the progression of aging, but also seems to suppress it. However, as indicated by gene expression analysis in aging mice, aging is not a linear model, but is represented by nonlinear dynamic changes. Consequently, the development of experimental models and analytical methods that enhance temporal resolution through time-series analysis, tailored to spatial resolution, such as cell distribution and organ specificity, is progressing. Moreover, in recent years, in addition to anti-aging efforts targeting epigenomic variations, global attention has increasingly focused on research and development aimed at rejuvenating treatments, thus leading to the birth of many biotech companies. Aging Hallmarks such as inflammation, stem cells, metabolism, genomic instability, and autophagy, interact closely with the epigenome. Various postnatal and reversible epigenomic controls of aging, including Yamanaka factors (OKSM and OSK), are now entering a new phase. In the future, the development of aging control using diverse modalities, such as mRNA, artificial peptides, and genome editing, is expected, along with an improved molecular understanding of aging and identification of useful biomarkers.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Heart failure in the elderly and nutrition].","authors":"","doi":"10.3143/geriatrics.61.134","DOIUrl":"https://doi.org/10.3143/geriatrics.61.134","url":null,"abstract":"","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 2","pages":"134-138"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Relationship between the type and number of social participation events and the cognitive function in older diabetics].","authors":"Satoshi Ida, Kanako Imataka, Masaki Morii, Kazuya Murata","doi":"10.3143/geriatrics.61.179","DOIUrl":"https://doi.org/10.3143/geriatrics.61.179","url":null,"abstract":"<p><strong>Objective: </strong>To examine the relationship between the type and number of social participation events and the cognitive function in elderly patients with diabetes.</p><p><strong>Methods: </strong>The subjects were diabetic outpatients of ≥60 years of age who were managed at Ise Red Cross Hospital. Mild cognitive impairment (MCI) and dementia were assessed using a self-administered dementia checklist. Six types of social participation activities and the number of participants were investigated. A logistic regression analysis with MCI and dementia as dependent variables, social participation as an explanatory variable, and adjustment variables was used to calculate the odds ratios for social participation according to the presence of MCI and dementia.</p><p><strong>Results: </strong>In total, 352 patients were included in the analysis. Volunteer activities (P=0.012), hobbies (P=0.006), activities to share skills and experiences (P=0.026), and work (P=0.003) were significantly associated with dementia. Regarding the association between the amount of social participation and dementia, there was a decrease in the risk of dementia when the number of social participation was 2. However, social participation was not significantly associated with MCI in this study.</p><p><strong>Conclusion: </strong>The type and number of social participation events were found to be associated with the risk of dementia in elderly patients with diabetes.</p>","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 2","pages":"179-185"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Fecal impaction is one of risk factors for severe hypermagnesemia in oral magnesium preparations: a review of the literature in Japan].","authors":"","doi":"10.3143/geriatrics.61.103","DOIUrl":"10.3143/geriatrics.61.103","url":null,"abstract":"","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 2","pages":"103-113"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Diagnosis and treatment of HFpEF].","authors":"","doi":"10.3143/geriatrics.61.124","DOIUrl":"10.3143/geriatrics.61.124","url":null,"abstract":"","PeriodicalId":35593,"journal":{"name":"Japanese Journal of Geriatrics","volume":"61 2","pages":"124-128"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}