Acta Microbiologica Bulgarica最新文献_第4页

Pathogenesis, Diseases, Immune Response, and Chemotherapy of Genus Simplexvirus 单纯疱疹病毒属的发病机制、疾病、免疫反应和化疗

Acta Microbiologica Bulgarica Pub Date : 2023-06-01 DOI: 10.59393/amb23390202

N. Hristova, A.S. Galabov

引用次数: 0

Koi Herpesvirus Highlights and Potential of Probiotics to Reduce or Even to Prevent Koi Herpesvirus Infection 锦鲤疱疹病毒的特点和益生菌减少甚至预防锦鲤疱疹病毒感染的潜力

Acta Microbiologica Bulgarica Pub Date : 2023-06-01 DOI: 10.59393/amb23390203

K. Mancheva, S. Danova, N. Vilhelmova-Ilieva, L. Simeonova, L. Dobreva, G. Atanasov

{"title":"Koi Herpesvirus Highlights and Potential of Probiotics to Reduce or Even to Prevent Koi Herpesvirus Infection","authors":"K. Mancheva, S. Danova, N. Vilhelmova-Ilieva, L. Simeonova, L. Dobreva, G. Atanasov","doi":"10.59393/amb23390203","DOIUrl":"https://doi.org/10.59393/amb23390203","url":null,"abstract":"Koi herpesvirus (KHV) is a highly contagious virus that causes high morbidity and mass mortality of koi carp (Cyprinus rubrofuscus Lacepède, 1803), common carp (Cyprinus carpio Linnaeus, 1758) and its ornamental (coloured) varieties. Koi herpesvirus disease (KHVD) is one of the major factors that cause sig¬nificant economic losses affecting both wild and cultured populations of common and koi carp worldwide. It is thought that there is no effective treatment for KHVD. The usage of vaccines for aquatic animals and water environments is limited, associated with the risk of viral reactivation and reversion to virulence. In Europe, for example, no commercial vaccine for KHVD is available. On the other side, probiotic additives are one of the most prospective, promising, and safe alternatives of drugs, that provide fish health benefits such as improvement of fish immune resistance and increased growth performance. This paper provides a thoroughgoing analysis of the knowledge about Koi herpesvirus and the disease, its distribution, and con¬ventional treatment methods. We discuss the potential of probiotics for improvement of growth rate and carp immune resistance, associated with the fish mucosal immune system as the first immune barrier.","PeriodicalId":35526,"journal":{"name":"Acta Microbiologica Bulgarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135145299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Various therapies against SARS-CoV-2 针对SARS-CoV-2的各种疗法

Acta Microbiologica Bulgarica Pub Date : 2023-03-01 DOI: 10.59393/amb23390101

A. Valsamatzi-Panagiotou, M. Traykovska, G.Y. Miloshev, R. Penchovsky

{"title":"Various therapies against SARS-CoV-2","authors":"A. Valsamatzi-Panagiotou, M. Traykovska, G.Y. Miloshev, R. Penchovsky","doi":"10.59393/amb23390101","DOIUrl":"https://doi.org/10.59393/amb23390101","url":null,"abstract":"An outbreak of coronavirus SARS-CoV-2 infection in December 2019 in Wuhan, a province of Chi¬na, has caused a worldwide pandemic that led to devastating effects on healthcare systems and the econ¬omy worldwide. The contagiousness of the infection and the consequences of the disease in everyday life highlighted the great need for a suitable treatment against coronavirus as soon as possible. Therefore, lots of scientists all around the world focused on the discovery of a proper therapy against the virus. The pres¬ent article explains the structure of the virus, the pathophysiology of the infection with SARS-CoV-2, and various therapies against SARS-CoV-2. The first data that concern the effectiveness of vaccines from the countries that have already started mass vaccinations are positive. However, it is very early to conclude about the efficacy of vaccines in the population. The appearance of novel virus mutations raises concerns and forces some countries to impose further restrictions. The latest and the most contagious variant, known as Omicron, seems to decrease the global pandemic significantly. New SARS-CoV-2 therapies are suggest¬ed based on antisense technology.","PeriodicalId":35526,"journal":{"name":"Acta Microbiologica Bulgarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135532398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blood Clotting Disorders and Thrombosis: an Important Complication of COVID-19 凝血障碍和血栓形成:COVID-19的重要并发症

Acta Microbiologica Bulgarica Pub Date : 2023-03-01 DOI: 10.59393/amb23390102

H. Mahmoudi, A.E. Vardanjani

引用次数: 2

An Overview of the Most Used Methods to Determine the In Vitro Antibacterial Activity of Honey 测定蜂蜜体外抗菌活性的常用方法综述

Acta Microbiologica Bulgarica Pub Date : 2023-03-01 DOI: 10.59393/amb23390104

M. Bouacha, S. Besnaci, I. Boudiar

引用次数: 1

Genus Simplexvirus: Life cycle 单纯病毒属:生命周期

Acta Microbiologica Bulgarica Pub Date : 2023-03-01 DOI: 10.59393/amb23390103

N. Hristova, A.S. Galabov

引用次数: 0

Effects of Ultrasonic Specific Energy on Time-Dependent Inactivation Rate of Proteus mirabilis and Streptococcus sanguinis 超声比能对变形杆菌和血链球菌时间依赖性失活率的影响

Acta Microbiologica Bulgarica Pub Date : 2023-03-01 DOI: 10.59393/amb23390108

Ö. Kekeç, B. Gökalsın, B. Açıkgöz, D.Ö. Özdaş, C. Sesal

引用次数: 0

In Vitro Activity of Ceftazidime-Avibactam against 3rd Generation Cephalosporin and Carbapenem Resistant Gram-Negative Bacteria Obtained from Blood and Fecal Samples of Hematopoietic Stem Cell Transplanted Patients 头孢他啶-阿维巴坦对造血干细胞移植患者血液和粪便中第3代头孢菌素和碳青霉烯耐药革兰氏阴性菌的体外活性研究

Acta Microbiologica Bulgarica Pub Date : 2023-03-01 DOI: 10.59393/amb23390111

D. Niyazi, T. Stoeva

{"title":"In Vitro Activity of Ceftazidime-Avibactam against 3rd Generation Cephalosporin and Carbapenem Resistant Gram-Negative Bacteria Obtained from Blood and Fecal Samples of Hematopoietic Stem Cell Transplanted Patients","authors":"D. Niyazi, T. Stoeva","doi":"10.59393/amb23390111","DOIUrl":"https://doi.org/10.59393/amb23390111","url":null,"abstract":"The recipients of hematopoietic stem cell transplantation (HSCT) tend to develop invasive infections because of the immunosuppression caused by the underlying disease or the transplantation itself. The gastro¬intestinal tract is the major source of causative agents, often demonstrating multidrug resistance. The aim of this study is to investigate the in vitro activity of ceftazidime-avibactam (CZA) against 3rd generation ceph¬alosporin and/or carbapenem resistant (CPR) Gram-negative bacteria obtained from blood and fecal sam¬ples of patients following HSCT. Thirty-five clinical isolates were studied (Enterobacterales, n=25, Pseu-domanas spp., n=8, A. baumannii, n=2). MALDI Biotyper (Bruker) and Phoenix system (BD) were used for identification and susceptibility testing. Multiplex PCR was performed to detect genes associated with beta-lactam resistance. In the studied group 96% of the enteric bacteria were Extended Spectrum Beta Lacta¬mase producers (ESBL) and all were susceptible to CZA. CZA demonstrated an excellent activity against piperacillin-tazobactam resistant isolates. Among the CPR isolates, 91% were CZA resistant and blaVIM, blaOXA-23 and blaOXA-24/40, blaOXA-48 genes were detected. In conclusion, an excellent activity of CZA against ESBL producing and piperacillin-tazobactam resistant Gram - negative isolates was found. Despite its potent activity against class A enzymes, avibactam failed to inactivate class B and class D carbapenemases.","PeriodicalId":35526,"journal":{"name":"Acta Microbiologica Bulgarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135532404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amaryllidaceae Alkaloids Inhibit the Growth of Endophytic Fungi 香菊科生物碱对内生真菌生长的抑制作用

Acta Microbiologica Bulgarica Pub Date : 2023-03-01 DOI: 10.59393/amb23390107

S. Berkov, E. Krumova, G. Stoyancheva, J. Miteva-Staleva, V. Dishliyska, N. Kostadinova, L. Georgieva, B. Sidjimova, M. Nikolova, M. Angelova, B. Mutafova

{"title":"Amaryllidaceae Alkaloids Inhibit the Growth of Endophytic Fungi","authors":"S. Berkov, E. Krumova, G. Stoyancheva, J. Miteva-Staleva, V. Dishliyska, N. Kostadinova, L. Georgieva, B. Sidjimova, M. Nikolova, M. Angelova, B. Mutafova","doi":"10.59393/amb23390107","DOIUrl":"https://doi.org/10.59393/amb23390107","url":null,"abstract":"The chemoecological role of the Amaryllidaceae alkaloids, accumulated in plants from the Amarylli¬doideae subfamily (Amaryllidaceae), is poorly studied. These alkaloids are known for their potent pharma¬cological activities, including anti-acetylcholinesterase (AChE), anti-tumoral, anti-microbial, anti-viral and cytotoxic. In the present work, the ability of some Amaryllidaceae alklaloids to inhibit the growth of endo¬phytic fungi was studied. A total of 115 endophytic fungal strains were isolated from Leucojum aestivum L. growing in geographycally distinct locations. Sixty-five stains, able to grow in laboratory conditions, were identified and classified into 31 species belonging to 11 phylogenetically diverse genera. The fungal species of genera Fusarium, Trichoderma and Talaromyces were predominant. The endophyte species and genera patterns were found to be different among the L. aestivum L. populations and plant organs. Galanthamine, epi -norgalanthamine and lycorine, as well as alkaloid fractions and extracts consisting of homolycorine-, haemanthamine-, tazettine- and Sceletium -type alkaloids as main components exhibited different growth inhibitory effects depending on fungal strain. An extract from Narcissus cv. Hawera, consisting of Scele¬tium -type alkaloids, showed the most effective and broad-spectrum inhibitory activity against the tested endophytic strains. The results indicate that the Amaryllidaceae alkaloids may play a role in the plant-en¬dophyte interactions.","PeriodicalId":35526,"journal":{"name":"Acta Microbiologica Bulgarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135532397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increase in the Amount of Soil Organic Matter and Populations of Microorganisms by Addition of Different Types of Compost for Sustainable Agriculture 可持续农业中添加不同类型堆肥对土壤有机质和微生物数量的影响

Acta Microbiologica Bulgarica Pub Date : 2023-03-01 DOI: 10.59393/amb23390109

L. Kabaivanova, L. Nacheva, A. Goushterova, N. Dinev

{"title":"Increase in the Amount of Soil Organic Matter and Populations of Microorganisms by Addition of Different Types of Compost for Sustainable Agriculture","authors":"L. Kabaivanova, L. Nacheva, A. Goushterova, N. Dinev","doi":"10.59393/amb23390109","DOIUrl":"https://doi.org/10.59393/amb23390109","url":null,"abstract":"Maintaining a positive balance of organic matter in arable land is a fundamental issue for sustain¬able agriculture. Environmentally friendly and cost-effective solutions applicable to large areas and also to small farms are needed. This is especially true for areas affected by environmental processes, leading to deteriorating soil fertility and limiting opportunities for organic farming. Organic fertilization through composting is an effective method of maintaining soil fertility. Due to shortage of traditional organic fertil¬izers, new sources of organic matter are being sought, such as agricultural waste, sewage sludge, household or industrial waste. Identification of waste products and possibilities for their use in compost production with a certain composition was carried out. Physico-chemical characteristics of the starting materials be¬fore composting was carried out. Estimation of their effectiveness as soil improvers on two types of soils - leached cinnamon forest soil from the area of village of Chelopechene, near Sofia, Bulgaria and alluvial meadow soil from the area of Tsalapitsa, Plovdiv region, Bulgaria was accomplished. When composting the ameliorants with the first type of soil, all additives led to positive changes in soil organic matter, while composting ameliorants with the second type of soil, the added organic materials provided a lower degree of storage of organic matter. Therefore, compost addition to leached cinnamon forest soil is more reason¬able, ensuring good stock in the form of humin. Application of compost led to increase in the populations microorganisms, including bacteria and fungi, which is a good indicator of increased soil microbial activity in respective treatments.","PeriodicalId":35526,"journal":{"name":"Acta Microbiologica Bulgarica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135532395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0