Clinical autonomic research : official journal of the Clinical Autonomic Research Society最新文献

{"title":"The exercise pressor reflex: An update.","authors":"André L Teixeira,&nbsp;Lauro C Vianna","doi":"10.1007/s10286-022-00872-3","DOIUrl":"https://doi.org/10.1007/s10286-022-00872-3","url":null,"abstract":"<p><p>The exercise pressor reflex is a feedback mechanism engaged upon stimulation of mechano- and metabosensitive skeletal muscle afferents. Activation of these afferents elicits a reflex increase in heart rate, blood pressure, and ventilation in an intensity-dependent manner. Consequently, the exercise pressor reflex has been postulated to be one of the principal mediators of the cardiorespiratory responses to exercise. In this updated review, we will discuss classical and recent advancements in our understating of the exercise pressor reflex function in both human and animal models. Particular attention will be paid to the afferent mechanisms and pathways involved during its activation, its effects on different target organs, its potential role in the abnormal cardiovascular response to exercise in diseased states, and the impact of age and biological sex on these responses. Finally, we will highlight some unanswered questions in the literature that may inspire future investigations in the field.</p>","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"271-290"},"PeriodicalIF":5.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40140338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autonomic function testing in multiple system atrophy: a prognostic biomarker? and other updates on recent autonomic research.","authors":"Mitchell G Miglis,&nbsp;Srikanth Muppidi","doi":"10.1007/s10286-022-00883-0","DOIUrl":"https://doi.org/10.1007/s10286-022-00883-0","url":null,"abstract":"","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"219-221"},"PeriodicalIF":5.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40579389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple system atrophy laryngeal stridor treated with radiofrequency-assisted posterior cordotomy and arytenoidectomy.","authors":"Sergio A Castillo-Torres,&nbsp;María Viti,&nbsp;Viviana Alexandra Martínez-Villota,&nbsp;Malco Rossi,&nbsp;Marcelo Merello","doi":"10.1007/s10286-022-00876-z","DOIUrl":"https://doi.org/10.1007/s10286-022-00876-z","url":null,"abstract":"","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"303-306"},"PeriodicalIF":5.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40518703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of signal-averaging and regression approaches to analyzing sympathetic transduction.","authors":"Myles W O'Brien,&nbsp;Beverly D Schwartz,&nbsp;Jennifer L Petterson,&nbsp;Derek S Kimmerly","doi":"10.1007/s10286-022-00874-1","DOIUrl":"https://doi.org/10.1007/s10286-022-00874-1","url":null,"abstract":"<p><strong>Purpose: </strong>Spontaneous sympathetic transduction reflects the vascular and/or pressor responses to bursts of muscle sympathetic nerve activity (MSNA). Separately, signal-averaging and regression-based approaches have been implemented to quantify resting sympathetic transduction. It is unknown whether the outcomes of these analytical approaches provide (dis)similar information, which is imperative for between-study comparisons and the amalgamation of results for synthesis of multiple studies (i.e., meta-analyses). We explored the diastolic blood pressure (DBP) responses to spontaneous bursts of MSNA between these two methods of analysis.</p><p><strong>Methods: </strong>Resting beat-by-beat DBP (via finger photoplethysmography) and common peroneal nerve MSNA (via microneurography) were recorded in 52 healthy, normotensive adults (age 38 ± 20 years; 19 females). For the signal-averaged method, transduction was quantified as the mean peak increase in DBP (ΔDBP) during the 12 cardiac cycles following each MSNA burst. In addition, DBP was regressed to a moving two-cardiac-cycle window of normalized relative burst height (mmHg/relative %) to provide the regression-based transduction outcome.</p><p><strong>Results: </strong>The signal-averaged (1.2 ± 0.7 mmHg) and regression-based approaches (0.009 ± 0.016 mmHg/%) were unrelated (ρ = 0.03, p = 0.86). Adding to the discrepancy, only the signal-averaging approach demonstrated a lower transduction in middle-aged-older males versus younger males.</p><p><strong>Conclusions: </strong>The decision of which method to use when calculating sympathetic transduction influences study outcomes, with the two most common methods of determining transduction being unrelated. There are challenges of making sweeping conclusions across studies if different analysis strategies are implemented. An understanding of when to use each method is needed to adopt a harmonized approach to quantifying sympathetic transduction.</p>","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"299-302"},"PeriodicalIF":5.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40141015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The interplay between autonomic tone and atrial arrhythmias.","authors":"Matthew A Carlisle,&nbsp;Jonathan P Piccini,&nbsp;Marat Fudim","doi":"10.1007/s10286-022-00881-2","DOIUrl":"https://doi.org/10.1007/s10286-022-00881-2","url":null,"abstract":"","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"223-225"},"PeriodicalIF":5.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40556056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bishop Dr. Karl Golser Prize 2022 awarded to Prof. Wolfgang Singer.","authors":"Gregor K Wenning,&nbsp;Pamela Bower","doi":"10.1007/s10286-022-00875-0","DOIUrl":"https://doi.org/10.1007/s10286-022-00875-0","url":null,"abstract":"","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"227-228"},"PeriodicalIF":5.8,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40641570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanisms of post-prandial symptoms in postural tachycardia syndrome and other updates on recent autonomic research.","authors":"Mitchell G Miglis,&nbsp;Nicholas Larsen,&nbsp;Srikanth Muppidi","doi":"10.1007/s10286-022-00863-4","DOIUrl":"https://doi.org/10.1007/s10286-022-00863-4","url":null,"abstract":"","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"87-89"},"PeriodicalIF":5.8,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40314321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional brain neuroimaging as a tool to study gastrointestinal manifestations in patients with Parkinson's disease.","authors":"Ryuji Sakakibara","doi":"10.1007/s10286-022-00852-7","DOIUrl":"https://doi.org/10.1007/s10286-022-00852-7","url":null,"abstract":"","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"7-8"},"PeriodicalIF":5.8,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39847915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human pluripotent stem cell-derived functional sympathetic neurons express ACE2 and RAAS components: a framework for studying the effect of COVID-19 on sympathetic responsiveness.","authors":"Hsueh-Fu Wu,&nbsp;Chia-Wei Huang,&nbsp;Kanupriya R Daga,&nbsp;Ross A Marklein,&nbsp;Natalia Ivanova,&nbsp;Nadja Zeltner","doi":"10.1007/s10286-021-00850-1","DOIUrl":"https://doi.org/10.1007/s10286-021-00850-1","url":null,"abstract":"","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"59-63"},"PeriodicalIF":5.8,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39869381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep syncope: a new clinical entity or just a vasovagal syncope during wakefulness after sleep onset?","authors":"Philippe T Gilchrist,&nbsp;Federica Provini","doi":"10.1007/s10286-021-00847-w","DOIUrl":"https://doi.org/10.1007/s10286-021-00847-w","url":null,"abstract":"","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"5-6"},"PeriodicalIF":5.8,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39810083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}