Clinical autonomic research : official journal of the Clinical Autonomic Research Society最新文献_第10页

Roles of catechol neurochemistry in autonomic function testing. 儿茶酚神经化学在自主神经功能测试中的作用。

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2018-04-28 DOI: 10.1007/s10286-018-0528-9

David S Goldstein, William P Cheshire

引用次数: 0

Increased cardiac sympathetic activity: Cause or compensation in vasovagal syncope? 心脏交感神经活动增加:血管迷走神经性晕厥的原因还是代偿?

IF 5.8

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2018-04-03 DOI: 10.1007/s10286-018-0524-0

Robert A Larson, Mark W Chapleau

引用次数: 6

Modeling human orthostatic responses on the Moon and on Mars. 模拟人类在月球和火星上的直立反应。

IF 5.8

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2018-04-26 DOI: 10.1007/s10286-018-0527-x

Paula Beck, Jens Tank, Peter Gauger, Luis E J Beck, Hubert Zirngibl, Jens Jordan, Ulrich Limper

{"title":"Modeling human orthostatic responses on the Moon and on Mars.","authors":"Paula Beck, Jens Tank, Peter Gauger, Luis E J Beck, Hubert Zirngibl, Jens Jordan, Ulrich Limper","doi":"10.1007/s10286-018-0527-x","DOIUrl":"https://doi.org/10.1007/s10286-018-0527-x","url":null,"abstract":"Purpose: Since manned missions to the Moon and Mars are planned, we conducted active standing tests with lunar, Martian, terrestrial, and 1.8 loads of inertial resistance (+Gz) modeled through defined parabolic flight maneuvers. We hypothesized that the cardiovascular response to active standing is proportional to the +Gz load.Methods: During partial-+Gz parabolic flights, 14 healthy test subjects performed active stand-up maneuvers under 1 +Gz, lunar (0.16 +Gz), Martian (0.38 +Gz), and hyper inertial resistance (1.8 +Gz) while heart rate and finger blood pressure were continuously monitored. We quantified amplitudes and timing of orthostatic response immediately following standing up.Results: The maximum early heart rate increase was 21 (SD ± 10) bpm with lunar, 23 (± 11) bpm with Martian, 34 (± 17) bpm with terrestrial +Gz, and 40 (± 11) bpm hyper +Gz. The time to maximum heart rate increased gradually with increasing loads of inertial resistance. The transient blood pressure reduction was most pronounced with hyper +Gz but did not differ significantly between lunar and Martian +Gz. The mean arterial pressure nadir was reached significantly later with Martian and lunar compared to 1 +Gz. Paradoxically, the time for blood pressure to recover was shortest with terrestrial +Gz.Conclusion: While load of inertial resistance directly affects the magnitude of the transient blood pressure reduction and heart rate response to active standing, blood pressure stabilization is most rapidly attained during terrestrial +Gz. The observation might suggest that the human cardiovascular system is tuned to cope with orthostatic stress on earth.","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"325-332"},"PeriodicalIF":5.8,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10286-018-0527-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36048113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Extraterrestrial autonomic function. 外星自主功能。

IF 5.8

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2018-05-15 DOI: 10.1007/s10286-018-0531-1

Thomas G Smith

引用次数: 1

The pathophysiology of the trigeminal autonomic cephalalgias, with clinical implications. 三叉神经自主神经性头痛的病理生理学及其临床意义。

IF 5.8

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2017-09-23 DOI: 10.1007/s10286-017-0468-9

Mads C J Barloese

{"title":"The pathophysiology of the trigeminal autonomic cephalalgias, with clinical implications.","authors":"Mads C J Barloese","doi":"10.1007/s10286-017-0468-9","DOIUrl":"https://doi.org/10.1007/s10286-017-0468-9","url":null,"abstract":"The hallmark of primary headaches belonging to the group known as the trigeminal autonomic cephalalgias is unilateral headache accompanied by cranial autonomic symptoms. Being relatively rare and poorly understood, they represent a clinical challenge, leading to underdiagnosis and undertreatment. While the headache is the most obvious and disabling symptom, it is only part of a complex symptomatology which hints at the involved pathophysiological mechanisms. Activation of the trigeminal-autonomic reflex results in the aforementioned cranial autonomic symptoms, which are well understood; however, it is obvious that this brainstem reflex is regulated by higher centers that seemingly play a pivotal role in the attacks and the wide range of other symptoms indicating a homeostatic disturbance. These symptoms, as well as a number of well-validated findings, implicate the hypothalamus in the pathophysiology. over the course of the past 2-3 decades, novel therapies and technological advances have helped increase our knowledge of these clinical syndromes, and will likely continue to do so in the coming years as we witness the arrival of new drugs and neurostimulation options. In this review, the clinical presentation for cluster headache, paroxysmal hemicrania, short-lasting unilateral neuralgiform headache with conjunctival injection and tearing, and hemicrania continua is covered, along with our current understanding of the common pathophysiology and clinical manifestations.","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"315-324"},"PeriodicalIF":5.8,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10286-017-0468-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35540402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Autonomic nervous system and cancer. 自主神经系统和癌症。

IF 5.8

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2018-03-28 DOI: 10.1007/s10286-018-0523-1

Marta Simó, Xavier Navarro, Victor J Yuste, Jordi Bruna

引用次数: 22

Catechol neurochemistry in the autonomic clinic: helpful but not absolutely required. 自主神经临床中的儿茶酚神经化学:有帮助但不是绝对必需的。

IF 5.8

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2018-05-23 DOI: 10.1007/s10286-018-0533-z

Jeremy K Cutsforth-Gregory

引用次数: 0

In memoriam: Sir Roger Bannister 1929-2018. 纪念罗杰·班尼斯特爵士1929-2018。

IF 5.8

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2018-05-30 DOI: 10.1007/s10286-018-0535-x

Walter Struhal, Roland D Thijs, Anne Pavy-Le Traon, Gregor Wenning, Jean Michel Senard

引用次数: 0

Sympathetic neurograms showing characteristics of both muscle and skin sympathetic nerve activity in a case with pure autonomic failure. 单纯自主神经衰竭患者的交感神经图显示肌肉和皮肤交感神经活动的特征。

IF 5.8

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2018-01-08 DOI: 10.1007/s10286-017-0497-4

Kazumasa Shindo, Akane Satake, Naofumi Kurita, Toko Sato, Mai Tsuchiya, Yuta Ichinose, Takanori Hata, Kishin Koh, Takamura Nagasaka, Yoshihisa Takiyama

引用次数: 0

Neural pathways involved in infection-induced inflammation: recent insights and clinical implications. 神经通路参与感染引起的炎症:最近的见解和临床意义。

IF 5.8

Clinical autonomic research : official journal of the Clinical Autonomic Research Society Pub Date : 2018-06-01 Epub Date: 2018-03-14 DOI: 10.1007/s10286-018-0518-y

Marion Griton, Jan Pieter Konsman

{"title":"Neural pathways involved in infection-induced inflammation: recent insights and clinical implications.","authors":"Marion Griton, Jan Pieter Konsman","doi":"10.1007/s10286-018-0518-y","DOIUrl":"https://doi.org/10.1007/s10286-018-0518-y","url":null,"abstract":"Although the immune and nervous systems have long been considered independent biological systems, they turn out to mingle and interact extensively. The present review summarizes recent insights into the neural pathways activated by and involved in infection-induced inflammation and discusses potential clinical applications. The simplest activation concerns a reflex action within C-fibers leading to neurogenic inflammation. Low concentrations of pro-inflammatory cytokines or bacterial fragments may also act on these afferent nerve fibers to signal the central nervous system and bring about early fever, hyperalgesia and sickness behavior. In the brain, the preoptic area and the paraventricular hypothalamus are part of a neuronal network mediating sympathetic activation underlying fever while brainstem circuits play a role in the reduction of food intake after systemic exposure to bacterial fragments. A vagally-mediated anti-inflammatory reflex mechanism has been proposed and, in turn, questioned because the major immune organs driving inflammation, such as the spleen, are not innervated by vagal efferent fibers. On the contrary, sympathetic nerves do innervate these organs and modulate immune cell responses, production of inflammatory mediators and bacterial dissemination. Noradrenaline, which is both released by these fibers and often administered during sepsis, along with adrenaline, may exert pro-inflammatory actions through the stimulation of β1 adrenergic receptors, as antagonists of this receptor have been shown to exert anti-inflammatory effects in experimental sepsis.","PeriodicalId":354493,"journal":{"name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","volume":" ","pages":"289-299"},"PeriodicalIF":5.8,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10286-018-0518-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35914623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22