LLM Dergi最新文献

{"title":"Nakil Öncesi Yüksek Serum D-dimer Düzeyi Allojenik Hematopoietik Kök Hücre Nakli Yapılan Hastalarda Sağkalımı Belirlemede Prognostik Bir Belirteç Olabilir","authors":"Neslihan Mandacı Şanlı, Mehmet Emeklioğlu, Muzaffer Keklik, Ali Ünal","doi":"10.5578/llm.20219704","DOIUrl":"https://doi.org/10.5578/llm.20219704","url":null,"abstract":"","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122123073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ekstranodal Baş Boyun Diffüz Büyük B Hücreli Lenfomalarının Geriye Yönelik Olarak Değerlendirilmesi ve Nodal Hastalık ile Karşılaştırılması","authors":"Onur Kırkızlar, Tuğcan Alp Kırkızlar, Ufuk Demirci, Sedanur Karaman Gülsaran, Volkan Baş, E. G. Ümit, A. Demir","doi":"10.5578/llm.20219701","DOIUrl":"https://doi.org/10.5578/llm.20219701","url":null,"abstract":"","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122771939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kronik Lenfositik Lösemi Tanılı Hastalarda Prognostik Faktörlerin Klinik Bulgular ve Sağkalım Üzerindeki Etkilerinin Değerlendirilmesi","authors":"Emel İşleyen, Sema Karakuş, F. Şahin, Zerrin Yılmaz Çelik","doi":"10.5578/llm.20219703","DOIUrl":"https://doi.org/10.5578/llm.20219703","url":null,"abstract":"","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125891351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ruksolitinib Tedavisinin Aniden Kesilmesi Sonrasında Post-ET Myelofibrozis Bulgularında Alevlenme: Akılda Kalması Gereken Bir Klinik Tablo","authors":"Ufuk Demirci, Sedanur Kahraman Gülsaran, Volkan Baş, E. G. Ümit, Hakkı Onur Kırkızlar, A. Demir","doi":"10.5578/llm.20219705","DOIUrl":"https://doi.org/10.5578/llm.20219705","url":null,"abstract":"","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126401675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffüz Büyük B Hücreli Lenfomada Prognostik Skorlama Sistemlerinin Karşılaştırılması","authors":"Eda Ulusoy, Nergiz Erkut, Özlen Bektaş, Bircan Sönmez, Mehmet Sönmez","doi":"10.5578/llm.20219702","DOIUrl":"https://doi.org/10.5578/llm.20219702","url":null,"abstract":"","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115252816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival Data in Multiple Myeloma Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation","authors":"O. Bilgir, Cansu Atmaca Mutlu","doi":"10.5578/llm.20219803","DOIUrl":"https://doi.org/10.5578/llm.20219803","url":null,"abstract":"","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115221370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allogeneic Stem Cell Transplantation for Chronic Myelomonocytic Leukemia: A Single Center Experience","authors":"Ekin Kırcalı, G. Cengiz Seval, Cemaleddin Öztürk, Hülya Yılmaz, Gül Yavuz Ermiş, B. Karakaya, S. CİVRİZ BOZDAĞ, M. Kurt Yüksel, S. Toprak, P. Topçuoğlu","doi":"10.5578/llm.20219804","DOIUrl":"https://doi.org/10.5578/llm.20219804","url":null,"abstract":"","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129817676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brentuksimab Vedotin Treatment in Relaps Refractory Hodgkin Lymphoma: A Single Center Experience","authors":"Derya Koyun, G. Cengiz Seval, Metin Sökmen, E. Akkuş, Erden Atilla, S. CİVRİZ BOZDAĞ, P. Topçuoğlu, Ö. Arslan, T. Demirer, G. Gürman, O. Ilhan, M. Beksaç, S. Toprak","doi":"10.5578/llm.20219802","DOIUrl":"https://doi.org/10.5578/llm.20219802","url":null,"abstract":"","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125314292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Have COVID-19 Pandemic Restrictions Impacted the Functioning of the Hematology Clinic?","authors":"A. Tekinalp, A. Gemici, H. Z. Dikici, T. U. Kars, Furkan Selim Usta, Sinan Demircioğlu, Özcan Çeneli","doi":"10.5578/llm.20219801","DOIUrl":"https://doi.org/10.5578/llm.20219801","url":null,"abstract":"","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115506377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kronik Lenfositik Lösemi/Lenfoma Hastalarımızın Tek Merkezli 5 Yıllık Retrospektif Değerlendirmesi","authors":"Yeşim Ekşi Serel, Ali Serel, Tuğba Çetintepe, Demet Kiper Ünal, Asli Subasioglu, Şerife Solmaz, K. B. Payzin","doi":"10.5578/LLM.20219904","DOIUrl":"https://doi.org/10.5578/LLM.20219904","url":null,"abstract":"Objective: Chronic Lymphocytic leukemia (CLL) is a hematologic malignancy that is characterized by mature-appearing small lymphocytes in peripheral blood, bone marrow and lymphoid tissues. The aim of this study was to evaluate the general clinical and prognostic features, treatment regimens, response to treatment, clinical and laboratory markers of patients with CLL diagnosed in our center in order to contribute to approach algorithms for patients. Patients and Methods: In our study 216 patients diagnosed with CLL in the hematology clinic of İzmir Katip Çelebi Atatürk Training and Research Hospital between January 2015-December 2019 with available data were included. Treatment responses, survival status, factors effecting overall survival (OS) were evaluated retrospectively. Yeşim EKŞİ SEREL1 İD , Ali SEREL1 İD , Tuğba ÇETİNTEPE2 İD , Demet KİPER ÜNAL2 İD , Aslı SUBAŞIOĞLU3 İD , Şerife SOLMAZ2 İD , Kadriye Bahriye PAYZIN2 İD 1 İzmir Urla Devlet Hastanesi, Dahiliye Kliniği, İzmir, Türkiye 2 İzmir Katip Çelebi Atatürk Eğitim ve Araştırma Hastanesi, Hematoloji Kliniği, İzmir, Türkiye 3 İzmir Katip Çelebi Atatürk Eğitim ve Araştırma Hastanesi, Tıbbi Genetik Kliniği, İzmir, Türkiye Yeşim Ekşi Serel İzmir Urla Devlet Hastanesi, Dahiliye Kliniği, İzmir-Türkiye Geliş: 22.02.2021 Kabul: 01.03.2021 E-posta: yesimeksiii@hotmail.com Yazışma Adresi ARAŞTIRMA LLM Dergi 2020;4(4):71-78 • 10.5578/llm.20219904 Makale atıfı: Ekşi Serel Y, Serel A, Çetintepe T, Kiper Ünal D, Subaşıoğlu A, Solmaz Ş ve ark. Kronik lenfositik lösemi/ lenfoma hastalarımızın tek merkezli 5 yıllık retrospektif değerlendirmesi. LLM Dergi 2020;4(4):71-8. Kronik Lenfositik Lösemi/Lenfoma Hastalarımızın Tek Merkezli 5 Yıllık Retrospektif Değerlendirmesi LLM Dergi 2020;4(4):71-78 72 GİRİŞ Kronik Lenfositik Lösemi (KLL), fonksiyonel olarak olgunlaşmamış B lenfositlerin perifer kanı, kemik iliği, dalak ve lenf düğümlerinde monoklonal birikimi ile karakterize bir neoplazidir. Batı toplumunda en sık karşılaşılan lösemi tipidir (1). Batı yarım küredeki insidansı yılda 4.6/100.000 iken; doğu yarım kürede bu oran daha azdır (2). Fakat hastaların büyük bir kısmının semptomsuz olması nedeniyle gerçek sıklığını saptamak zordur. Batıda son yıllarda asemptomatik olguların eski yıllara göre çok arttığı ve %60 düzeyinde olduğu bildirilmektedir (3). Genelikle yaşlı popülasyonda ve ortalama 70 yaş civarında görülen bir hastalıktır. Klinik spektrumu oldukça geniştir. Hastalık asemptomatik seyredebileceği gibi anemi semptomları ya da hipersplenizm bulguları da görülebilir (4). KLL seyri sırasında özellikle kan elemanlarına karşı antikor üretilmesiyle otoimmün sitopeniler gelişebilmektedir (5). Hipogammaglobulinemi gelişebilmesi nedeniyle enfeksiyonlara yatkınlık sık görülmektedir (6). Evreleme amacı ile genellikle Rai ve Binet evreleme sistemleri kullanılmaktadır (7,8). Rai ve Binet evreleme sistemlerinin yanında hastalığın seyrini ve genel sağkalımı etkileyen kötü prognostik belirteçler arasında; erkek cinsiy","PeriodicalId":354438,"journal":{"name":"LLM Dergi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122389863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}