Jornal Brasileiro de Patologia e Medicina Laboratorial最新文献

{"title":"Consequences of late diagnosis paracoccidioidomycosis: case report","authors":"Joana A. B. Sousa, R. D. S. Sá, É. M. Pereira","doi":"10.5935/1676-2444.20210003","DOIUrl":"https://doi.org/10.5935/1676-2444.20210003","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71117408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPV detection in oral mucosa samples in pediatric patients","authors":"A. R. Gama, Marcos Antonio B. Carvalho, I. Wastowski, S. O. Rodrigues, M. F. Souza, Lais S. Botacin, M. Avelino, L. Carneiro","doi":"10.5935/1676-2444.20210005","DOIUrl":"https://doi.org/10.5935/1676-2444.20210005","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71117863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Umbilical cord constriction as a cause of intrauterine fetal death","authors":"Victor Antônio Kuiava, Henrique M. Pasqua, Ana Luiza da Silva Garcia, Bianca L. Barbarioli, F. M. Carlotto, Gabriel Costa, L. L. Brittes, Maiara Christine Macagnan, Nathália Dal Prá Zucco, Rubens Rodriguez","doi":"10.5935/1676-2444.20210002","DOIUrl":"https://doi.org/10.5935/1676-2444.20210002","url":null,"abstract":"The umbilical cord constriction (UCC) is an uncommon condition and an important etiology for stillborn fetuses. The main goal of this study was to verify the UCC occurrence as the cause of intrauterine fetal death, the associated etiology and its pathological characteristics. Therefore, a descriptive retrospective cross-sectional study was developed using the database from a Pathology Institute, in Brazil, from 1995 to 2017. The results presented a total of 1,359 embryo/fetus deaths – 69 (5.07%) due to UCC, 60.9% males and 39.1% females. The average age of pregnant women was 27.5 years ± 7.2 years of standard deviation (SD). The majority of deaths occurred during the second trimester (76.5%), followed by the first (14.7%) and third (8.8%) trimesters, respectively. One constriction alone was found in 87% of cases, 11% had two constrictions and only 1% had three or more. The presence of congenital malformations was detected in 20.2% of necropsies, the identification of chronic fetal distress was described in 71% of the technical reports and 17% of the cases had obstructive vasculopathy characteristics in microscopy analysis. Regarding the anatomopathological characteristics between the male and female sexes, no significant difference was found (p > 0.05) correlating gestational age, weight or congenital malformations. UCC was a cause of fetal death found in 5% of the cases, and it was linked to congenital malformations, fetal distress and obliterative vasculopathy.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71117335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertrophic pachymeningitis, IgG4-related disease: case report","authors":"G. Gerson, C. E. L. Soares, A. R. Rangel, G. Chagas, Daniel R. F. Távora, K. P. Fermon","doi":"10.5935/1676-2444.20210007","DOIUrl":"https://doi.org/10.5935/1676-2444.20210007","url":null,"abstract":"The IgG4-related disease (IgG4-RD) is a systemic disease recently characterized as an inflammatory condition generally related to the increase in serum IgG4 levels, a subclass of immunoglobulins (IgG) which corresponds to less than 6% of the total serum IgG, with singular histopathological features. The involvement of the central nervous system is rare and may be isolated or associated with other organs, mimicking tumors. Commonly, it involves the hypophysis, presenting hypophysitis as the main manifestation, but it can also affect the dura mater, presenting as IgG4-related hypertrophic pachymeningitis (IgG4-RHP). Neurological manifestations occur as a result of mass effect, typically due to vascular or nervous structures compression, resulting in functional deficits according to the anatomical site of the lesion. The main histopathological features are dense lymphoplasmacytic infiltrate, fibrosis arranged, at least focally, in a storiform pattern, and obliterative phlebitis, associated with increased numbers of IgG4+ plasma cells or an increased IgG4/IgG ratio in tissue. In this disease, the serum IgG4 levels are usually increased. The objective of this article is to report the case of a 37-year-old male patient who presented a pulsatile headache associated with diplopia and blurred vision. After radiological, histopathological and immunohistochemical studies, the diagnosis of IgG4-RHP was confirmed, besides presenting a literature review about IgG4-RD and IgG4-RHP.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71117984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications of idiopathic thrombocytopenic purpura in pregnancy: a review of literature","authors":"Camila L. Silva, Allyne Cristina Grando","doi":"10.5935/1676-2444.20210006","DOIUrl":"https://doi.org/10.5935/1676-2444.20210006","url":null,"abstract":"Introduction: Idiopathic thrombocytopenic purpura (ITP) is an acquired immune disorder that causes a reduction in platelet count, called thrombocytopenia. ITP during pregnancy usually presents some complications that may impair the outcome of pregnancy. Objective: This literature review aimed to identify the main complications of ITP in pregnancy and its consequences. Methodology: The bibliographic search was performed through scientific articles available in the Scielo and PubMed databases, of which 64 articles were selected, both in Portuguese and English. Results: The risk of postpartum hemorrhage, placental abruption, and neonatal thrombocytopenia are some complications that may occur during pregnancy. Conclusion: Pregnant women must be properly monitored during pregnancy so that there are no major complications.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extensive central ossifying fibroma of mandible: case report","authors":"H. G. F. Morais, L. M. Carlan, K. S. Rodrigues, E. Morais, R. Freitas","doi":"10.5935/1676-2444.20210024","DOIUrl":"https://doi.org/10.5935/1676-2444.20210024","url":null,"abstract":"A 34-year-old female patient attended a referral center for oral diagnosis presenting hardened increased volume in the posterior mandible. Panoramic radiography revealed a mixed unilocular lesion with clear and well-defined limits. The incisional biopsy showed proliferation of mesenchymal cells amid dense fibrous connective tissue. Mineralized material in different degrees of maturation was also observed. Regarding the histopathological aspects associated with the clinical, radiographic, and intraoperative data, the diagnosis of central ossifying fibroma (COF) was performed. COF has similar characteristics to other fibro-osseous lesions, and its diagnosis is a challenge for dental surgeons.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High peak of carbamylated hemoglobin discordant with urea level: a case report","authors":"Siti N. Ab-Rahim, Tuan S. Tuan-Ismail, H. Ibrahim, M. Hassan","doi":"10.5935/1676-2444.20210029","DOIUrl":"https://doi.org/10.5935/1676-2444.20210029","url":null,"abstract":"","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hereditary hemochromatosis associated with the development of liver cirrhosis","authors":"Taylla S. Costa, J. M. Ferreira, Marina Couto, R. Nascimento","doi":"10.5935/1676-2444.20210017","DOIUrl":"https://doi.org/10.5935/1676-2444.20210017","url":null,"abstract":"Hereditary hemochromatosis (HH) is an autosomal recessive disease, most often associated with mutations in the HFE gene, which result in continuous absorption of iron, causing its overload. Liver tissue is the main site of iron deposition; thus, high levels of iron, when interacting with oxygen, induce the formation of free radicals that will act on proteins, lipids, and deoxyribonucleic acid (DNA), which may trigger deleterious effects at cellular and tissue levels. In order to elucidate the development and progression of liver cirrhosis due to iron overload, the purpose of this study is to describe the pathophysiology of the hepatic system in patients diagnosed with HH. For this purpose, searches for scientific articles were carried out in the main academic databases. We found that patients diagnosed with HH are more likely to develop liver cirrhosis, since chronic iron deposition in liver tissue induces injury and consequent tissue regeneration, progressing to collagen fibers synthesis surrounding the hepatocytes, leading to loss of liver function and development of cirrhosis. Therefore, it is necessary to carry out tests such as iron, ferritin and transferrin measurements, to evaluate body’s iron stores, aiming at an early diagnosis of iron overload, thus avoiding deleterious damage at cellular and tissue levels.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance between histopathological and molecular methods in the detection of Helicobacter pylori","authors":"L. L. L. Silva, Igor M. C. Calassa, A. K. S. Oliveira, A. Ramos, J. C. Pontes, D. M. M. Cardoso, L. T. Rasmussem, L. Carneiro, M. Barbosa","doi":"10.5935/1676-2444.20210037","DOIUrl":"https://doi.org/10.5935/1676-2444.20210037","url":null,"abstract":"Introduction:","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71118570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronavirus and the puerperium: a case report","authors":"Lucas R. Mostardeiro, L. G. Schmitt, J. W. Xavier","doi":"10.5935/1676-2444.20200057","DOIUrl":"https://doi.org/10.5935/1676-2444.20200057","url":null,"abstract":"ABSTRACT COVID-19 started in China on December 31, 2019 and has since been the subject of several studies in medical field There is not much evidence about the pregnancy and puerperium with the susceptibility of coronavirus infection (COVID-19) The present work reports the laboratory and radiological aspects of a puerperium patient A positive test for severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) generally confirms the diagnosis of COVID-19, although false-positive and false-negative tests are possible The test considered the gold standard for the diagnosis of coronavirus infection (COVID-19) is from in vivo or post-mortem polymerase chain reaction (PCR) sample The purpose of the present case report is to demonstrate the case of a puerperium patient with an unfavorable clinical evolution, giving special attention to laboratory tests that were practically unchanged RESUMEN La COVID-19 se origino en China, el 31 de diciembre de 2019, y, desde entonces, ha sido objeto de varios estudios medicos No hay evidencias sobre la relacion del embarazo y del puerperio con la susceptibilidad a la infeccion por coronavirus El presente estudio reporta aspectos de laboratorio y radiologicos de una paciente en puerperio Una prueba positiva para el coronavirus del sindrome respiratorio agudo grave 2 (SARS-CoV-2) por lo general confirma el diagnostico de COVID-19, a pesar de que falso positivos y falso negativos sean posibles El metodo considerado el test de referencia para el diagnostico de la infeccion por coronavirus es la muestra in vivo o post mortem por reaccion en cadena de la polimerasa (PCR) El objetivo de este reporte es demostrar el caso de una paciente en puerperio con evolucion clinica desfavorable, poniendo especial atencion a los analisis de laboratorio que estaban practicamente sin cambios RESUMO A COVID-19 teve inicio na China, em 31 de dezembro de 2019 e, desde entao, tem sido alvo de diversos estudos na area medica Nao ha muitas evidencias sobre a relacao da gravidez e do puerperio com a suscetibilidade da infeccao pelo coronavirus O presente estudo relata os aspectos laboratoriais e radiologicos de uma paciente no puerperio Um teste positivo para a sindrome respiratoria aguda severa-coronavirus 2 (SARS-CoV-2) geralmente confirma o diagnostico de COVID-19, embora testes falso positivos e falso negativos sejam possiveis O exame considerado padrao-ouro para o diagnostico da infeccao pelo coronavirus e a amostra in vivo ou post-mortem por reacao em cadeia da polimerase (PCR) O objetivo deste relato e demonstrar o caso de uma paciente no puerperio com evolucao desfavoravel do quadro clinico, dando atencao especial para exames laboratoriais que estavam praticamente sem alteracoes","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47162075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}