Jornal Brasileiro de Patologia e Medicina Laboratorial最新文献_第10页

Coronavirus in a patient with hepatitis C: case report 丙型肝炎患者冠状病毒感染1例报告

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.5935/1676-2444.20200059

Lucas R. Mostardeiro, E. Antoniolli, J. W. Xavier

{"title":"Coronavirus in a patient with hepatitis C: case report","authors":"Lucas R. Mostardeiro, E. Antoniolli, J. W. Xavier","doi":"10.5935/1676-2444.20200059","DOIUrl":"https://doi.org/10.5935/1676-2444.20200059","url":null,"abstract":"ABSTRACT In February 2020, the World Health Organization (WHO) named the infection with the new coronavirus, which appeared in December 2019 in China, as Covid-19, and defined it as a worldwide pandemic There is not much evidence about the relationship between liver disease and Covid-19 Laboratory tests have played a fundamental role in confirming Covid-19, what is usually done by the polymerase chain reaction (PCR) sample The present study reports the laboratory aspects of a patient with type C hepatitis diagnosed with Covid-19 with an unfavorable evolution, devoting special attention to laboratory tests that were almost normal RESUMEN En febrero de 2020, la Organización Mundial de la Salud (OMS) nombró a la infección por el nuevo coronavirus, que surgió en diciembre de 2019 en China, Covid-19, declarándola como pandemia mundial No hay mucha evidencia sobre la relación entre enfermedades hepáticas y la Covid-19 Las pruebas de laboratorio han ocupado un lugar fundamental para confirmar la infección, lo que generalmente se hace por la muestra de reacción en cadena de la polimerasa (PCR) El presente estudio reporta los aspectos de laboratorio de un paciente con hepatitis C y diagnóstico de Covid-19 con evolución desfavorable, llamando la atención sobre pruebas de laboratorio con resultados casi normales RESUMO Em fevereiro de 2020, a Organização Mundial da Saúde (OMS) chamou a infecção pelo novo coronavírus, que surgiu em dezembro de 2019 na China, de COVID-19, definindo-a como pandemia mundial Não há muitas evidências sobre a relação das doenças hepáticas e a COVID-19 Os exames laboratoriais vêm exercendo um papel fundamental na confirmação da infecção, que é feita geralmente pela amostra de reação em cadeia da polimerase (PCR) O presente estudo relata os aspectos laboratoriais de um paciente portador de hepatite do tipo C e diagnóstico de COVID-19 com evolução desfavorável, dando atenção especial para exames laboratoriais que estavam pouco alterados","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71117211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Association of the CHGA gene polymorphism in patients with hemorrhagic stroke and/or aneurysm 出血性卒中和/或动脉瘤患者CHGA基因多态性的相关性

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.5935/1676-2444.20200012

Joanilson C. M. Santos Júnior, C. Fratelli, Alan Cristian F. Nóbrega, Suzana Cristina Rodrigues, L. Duarte, C. Silva, Jonathan D. Lima, L. Ferreira, D. Freire, V. F. Cipriano, Izabel Cristina R. Silva, Hélia Carla de Souza

{"title":"Association of the CHGA gene polymorphism in patients with hemorrhagic stroke\u0000 and/or aneurysm","authors":"Joanilson C. M. Santos Júnior, C. Fratelli, Alan Cristian F. Nóbrega, Suzana Cristina Rodrigues, L. Duarte, C. Silva, Jonathan D. Lima, L. Ferreira, D. Freire, V. F. Cipriano, Izabel Cristina R. Silva, Hélia Carla de Souza","doi":"10.5935/1676-2444.20200012","DOIUrl":"https://doi.org/10.5935/1676-2444.20200012","url":null,"abstract":"Introduction: Cerebrovascular diseases have been associated with several genes. Chromogranin A ( CHGA ) has been used as maker in cardiovascular disease. Therefore, evaluating the polymorphism and verifying its association with this pathology is very important to better understand this disease. Objective: The aim of this study was to identify the association between coding region polymorphism in -264 position of the CHGA gene ( Glu264Asp ) and hemorrhagic stroke (HS)/aneurysm in the Federal District, Brazil. Methods: This is a population-based case-control, involving 45 cases with HS and/or aneurysm. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method is used for genotyping these samples. A significance level of 5% was adopted. Results: The absence of the CC genotype the Glu264Asp CHGA polymorphism in the study participants and the significant presence of the GC heterozygote genotype were observed in this study. However, the distribution of genotypes did not differ statistically in the groups. Conclusion: The Glu264Asp CHGA polymorphism does not seem to contribute to the genesis of the CHGA protein expression in this patients group, but to understand whether or not there is a possible association of the pathology in question and whether the mutation will contribute in the gene therapy and thus to improve patients’ quality of life.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71116071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of quality indicators of cervical cytopathology tests carried out in a municipality of Paraná, Brazil 在巴西帕拉纳<e:1>市开展的宫颈细胞病理学检查质量指标评价

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.5935/1676-2444.20200041

Juliana Cristina Magalhães, Leonarda Silvestre Faria de Morais, J. Plewka, M. Turkiewicz, R. Amaral

{"title":"Evaluation of quality indicators of cervical cytopathology tests carried\u0000 out in a municipality of Paraná, Brazil","authors":"Juliana Cristina Magalhães, Leonarda Silvestre Faria de Morais, J. Plewka, M. Turkiewicz, R. Amaral","doi":"10.5935/1676-2444.20200041","DOIUrl":"https://doi.org/10.5935/1676-2444.20200041","url":null,"abstract":"Introduction: Although the criteria and recommendations are well defined to improve the quality of cervical cytopathology tests (Pap smear) in Brazil, the quality indicators of several laboratories are below the recommended standards. Objective: To evaluate the quality indicators of cervical cytopathology tests carried out by the Brazilian Unified Health System [Sistema Único de Saúde (SUS)]. Method: Cross-sectional study based on the results of cervical cytopathology tests conducted in the municipality of Cascavel, Paraná, Brazil, from January 2012 to December 2018. The study included 141,191 tests and the following variables were analyzed: sample suitability, cervical cytopathology tests result, and internal quality monitoring indicators recommended by the Brazilian Ministry of Health. Results: The percentage of unsatisfactory tests did not exceed 0.97%. The representation of the squamocolumnar junction ranged from 63% to 67.4%. The percentage of altered exams among the satisfactory samples ranged from 0.46% to 6.44%. The positivity index ranged from 0.46% to 6.44%, while the high-grade squamous intraepithelial lesion/satisfactory indicator ranged from 0.21% to 1.06%, atypical squamous cells of undetermined significance/altered ranged from 22.47% to 49.93%, atypical squamous cells of undetermined significance/satisfactory ranged from 0.1% to 2.57%: and atypical squamous cells of undetermined significance/squamous intraepithelial lesions ranged from 0.31 to 1.02. Conclusion: In 2012 and 2013, the high-grade squamous intraepithelial lesion/satisfactory and the positivity index indicators were below the recommended parameters, and in the remaining years, these indicators were within the parameters recommended. Consequently, a greater number of truly cancer precursor lesions were identified, demonstrating the importance of internal quality control in the prevention of cervical cancer.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71116875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Template for the laboratory’s report of 25-hydroxyvitamin D: recommendations form the Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) and the Brazilian Society of Endocrinology and Metabolism (SBEM) 25-羟基维生素D实验室报告模板:巴西临床病理/检验医学学会(SBPC/ML)和巴西内分泌与代谢学会(SBEM)的建议

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.5935/1676-2444.20200052

Carlos Eduardo S. Ferreira, C. A. Moreira, L. S. Vasconcellos

引用次数: 0

Mucoepidermoid carcinoma of the retromolar region: case report 后磨牙区粘液表皮样癌1例

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.1016/j.oooo.2019.06.284

C. Campos, H. Santos, E. Morais, A. N. Dantas, Rani Iani Costa Gonçado, H. Galvão, R. Freitas

引用次数: 0

Fórmulas de Martin, Friedewald e Cordova comparadas com a dosagem direta do LDL-C no sul do Brasil Fórmulas de Martin, Friedewald e Cordova comparadas com和dose - em direct do LDL-C no sul do brazil

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.5935/1676-2444.20200003

C. Cordova, Ariane S. Portal, Maurício Mendes de Cordova

引用次数: 2

A utilidade da captura híbrida para o HPV de alto risco em pacientes com atipia de células escamosas na colpocitologia 在阴道细胞学中，混合捕获对鳞状细胞异型患者高危HPV的有效性

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.5935/1676-2444.20200006

Flora Ávila Adorno, Daniele Cristina F. Lousada, Karina Munhoz de Paula Alves Coelho, Paulo Henrique Praça de França

引用次数: 0

Ductal carcinoma in situ of the breast: correlation of architectural, cytological, IHC findings and recurrence analysis 乳腺导管原位癌:建筑学、细胞学、免疫组化表现与复发分析的相关性

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.5935/1676-2444.20200018

Thiago Acrux, D. Athanazio, Débora Gaudêncio, C. Rocha

{"title":"Ductal carcinoma in situ of the breast: correlation of architectural, cytological,\u0000 IHC findings and recurrence analysis","authors":"Thiago Acrux, D. Athanazio, Débora Gaudêncio, C. Rocha","doi":"10.5935/1676-2444.20200018","DOIUrl":"https://doi.org/10.5935/1676-2444.20200018","url":null,"abstract":"Objective: This study evaluated the histopathological features of ductal carcinoma in situ (DCIS), including cytological grade, architectural pattern and immunohistochemistry (IHC) in pure DCIS and DCIS associated with invasive carcinoma of no special type (ICNST). Methods: We evaluated a series of 232 cases of pure DCIS and DCIS associated with ICNST from a total of 399 breast carcinomas from a population consisting by women diagnosed with breast cancer and submitted to breast surgery from 2011 to 2015. Results: DCIS presented a mixed architectural pattern in most cases (56%); the solid subtype was the most common morphology (30%). High-grade DCIS was identified in 84/221 cases (38%), and comedonecrosis was present in 106/221 cases (48%). High-grade was more common in the solid subtype (61/155 cases, 39%, p < 0.001). Tumor size was greater in the presence of comedonecrosis than in the absence (mean 27 vs 20 mm, p = 0.009). Estrogen receptor (ER) was positive in 81% of cases with a cribriform pattern (p = 0.013). Greater locoregional recurrence was found in the comedonecrosis (15%) and micropapillary (19%) subtypes in DCIS associated with ICNST. Conclusion: We observed a greater relationship of ER with the low nuclear grade, while Ki-67 was related to the high-grade. DCIS presented a higher nuclear grade compared to ICNST. The less common pure pattern was the micropapillary, and the most common, the solid. Comedonecrosis was more frequent in the solid pattern. Our results showed that high-grade was more common in the solid and comedo subtype, and low-grade was more frequent in the cribriform.","PeriodicalId":35397,"journal":{"name":"Jornal Brasileiro de Patologia e Medicina Laboratorial","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71116378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Primary gastric melanoma: a case report of a rare malignancy 原发性胃黑色素瘤:罕见恶性肿瘤1例报告

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.5935/1676-2444.20200034

Raquel Ferreira, Leonardo C Dentz, E. Assis, R. S. Laboissière

引用次数: 2

Basal cell carcinoma of the areola: a rare case report 乳晕基底细胞癌1例

Jornal Brasileiro de Patologia e Medicina Laboratorial Pub Date : 2020-01-01 DOI: 10.5935/1676-2444.20200044

M. Almeida, Michele R. Feroldi, L. Vianna, Eloisa B. Parreira

引用次数: 0