Medycyna wieku rozwojowego最新文献

{"title":"The practical significance of perinatal cardiology based on own experience.","authors":"M. Respondek-Liberska","doi":"10.34763/devperiodmed.20182203.229237","DOIUrl":"https://doi.org/10.34763/devperiodmed.20182203.229237","url":null,"abstract":"The article underlined the role of perinatal cardiology in contributing to the medical care of the pregnant woman taking into consideration the technical and medical progress which has made it possible to save not only human life but also its quality. The role of correct early diagnosis, as well as correct treatment was discussed and the results of such procedure demonstrated.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69886533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hospital-acquired enterobacteriaceae bloodstream infections in children.","authors":"M. Kłos, J. Wójkowska-Mach","doi":"10.34763/devperiodmed.20192302.131136","DOIUrl":"https://doi.org/10.34763/devperiodmed.20192302.131136","url":null,"abstract":"Among the different age groups of children, newborns are most exposed to hospital-acquired bloodstream infection (HA-BS1), especially those who are burdened with additional risk factors, such as low birth weight, immaturity or exposition to medical procedures.The aim of this study was to analyze the aetiology of HA-BS1 among children at high risk, including incidence and drug resistance.The data was obtained from the PubMed database and included medico/ articles as welI as UNICEF and WHO reports published from 2002 to 2017. The study focused on newborns and older children (under 18 years old) with BS1. The main eligibility criteria, aport from age, were Enterobacteriaceae HA-BS1, and the use of invasive medico/ procedures. It was demonstrated that the main risk factors of infection were age and medico/ procedures. Due to non-specific symptoms, sepsis is difficult to diagnose, a fact which leads to a high mortality rate in newborns.The existence of such mufti-drug resistant strains as Extended-Spectrum β-Lactamases (ESBLs) or Carbapenem-Resistant Enterobacteriaceae (CRE) phenotypes is a grave couse for concern.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69887142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical course and treatment of children and adolescents with the preexcitation syndrome - Own studies.","authors":"A. Stasiak, K. Niewiadomska-Jarosik, P. Kędziora","doi":"10.34763/devperiodmed.20182202.113122","DOIUrl":"https://doi.org/10.34763/devperiodmed.20182202.113122","url":null,"abstract":"INTRODUCTION\u0000Essentially, preexcitation syndrome is the presence of an accessory pathway in the heart, which can lead to serious consequences, ranging from atrioventricular reentrant tachycardia to sudden cardiac death. Wolff-Parkinson-White syndrome is the most common preexcitation syndrome.\u0000\u0000\u0000AIM OF THE STUDY\u0000The aim of the study was to evaluate the clinical course of the disease, as well as the treatment of children and adolescents hospitalized in the Department of Pediatric Cardiology in the years 2008-2015.\u0000\u0000\u0000MATERIALS AND METHODS\u0000The study was carried out in 45 children (62 % male, 38% female; the mean age 11 years). During the study we analyzed 12-lead ECG, 24-hour Holter ECG, echocardiography and the cycloergometric exercise test. The results of treatment were also discussed.\u0000\u0000\u0000RESULTS\u0000Apart from the typical features of preexcitation, the most prevalent abnormality found in ECG was atrioventricular reentrant tachycardia. In 24-hour Holter ECG the most frequently detected disorders were premature ventricular beats and premature atrial contractions. Structural heart defects were detected in 8.9% of the children. The cycloergometric exercise test was positive in 8.9% of patients. The mean duration of symptoms before the diagnosis was 2.5 years. 25% of the patients were asymptomatic. 42.2% of the children needed antiarrhythmic therapy, while 44.4% had accessory pathways ablated.\u0000\u0000\u0000CONCLUSIONS\u0000The most common symptom of preexcitation in the study group were heart palpitations. The most frequent type of arrhythmia in children with preexcitation syndrome was orthodromic atrioventricular reentrant tachycardia. For the majority of older children ablation of the accessory pathway was a recommended form of treatment. In younger children the standard preventive pharmacological treatment was applied for 6 to 12 months.Charakterystyczną cechą zespołów preekscytacji jest obecność dodatkowej, nieprawidłowej drogi przewodzenia w sercu. Najczęstszym typem zespołu preekscytacji jest zespół Wolffa-Parkinsona-White'a.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69886196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anovestibular fistula in an infant with retroviral infection - Case report.","authors":"D. Makhija, H. Shah, Charu Tiwari, J. Desale","doi":"10.34763/devperiodmed.20172102.98100","DOIUrl":"https://doi.org/10.34763/devperiodmed.20172102.98100","url":null,"abstract":"A vestibular fistula with a normal anus is a rare subtype of anorectal malformation seen more often in East Asia and India. Though mostly congenital, some authors have suggested acquired etiologies for this condition. Infants with retroviral infection have been reported to develop acquired rectovestibular fistulas. We report a case of an infant anovestibular fistula in a patient with retroviral infection.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69886456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asymmetric neonatal spasms as an early sign of brain malformation potentially caused by regular light alcohol consumption during the first 22 weeks of pregnancy, a clinical case report.","authors":"Olha Tychkivska, C. Go, Y. Korzhynskyy, Oksana Ostalska","doi":"10.34763/devperiodmed.20192301.1520","DOIUrl":"https://doi.org/10.34763/devperiodmed.20192301.1520","url":null,"abstract":"INTRODUCTION\u0000Epileptic spasms are seizures usually associated with a severe developmental epilepsy syndrome with onset in the first year of life, peaking between 3 and 1O months of age [12]. A variety of disorders can cause epileptic spasms, with the etiology driving management, prognosis, and overall outcome. Preexisting brain damage has been demonstrated in 60% to 90% of the cases reflecting pre-, peri-, or postnatal brain injury that may usually be determined by history and clinical neurologie examination. Cerebra/ malformations may account for up to 30% of the cases [2]. Prenatal a/coho/ exposure can permanently damage the brain, affecting important structures, such as the cerebellum, corpus callosum as we/I as specific cell populations in many other regions of the brain. No one knows what a \"safe\" amount of a/coho/ consumption du ring pregnancy may be [3].\u0000\u0000\u0000OBJECTIVE\u0000The aim of this article is to present a clinical case of a large brain tempora/ lobe malformation which was recognized after a very early onset of spasms registered on video EEG-monitoring followed by MRI findings and to put forward the assumption that regular consumption of light alcoholic drinks even in low doses could con tribute to irreversible brain damage in the fetus.\u0000\u0000\u0000MATERIAL AND METHODS\u0000All patient data were collected from the N/CU and Newborn Patho/ogy Department of Lviv City Children's Clinical Hospital Health Record Department, and included the hospital and clinic records by the staff neurologist, neurophysiologist, and pediatrician, as we/I as EEG records in the postneonatal period. The mother was interviewed to clarify the pregnancy course data. The mother's consent was obtained for publication.\u0000\u0000\u0000RESULTS\u0000Asymmetric spasms, which were recognized as seizures on the 4th day of the child's life white recording video EEG, urged the physicians towards further diagnostic investigations. Primarily the child was diagnosed with neonatal abstinence syndrome on the 2nd day of life based on clinical and patient history data, but on the following day episodes of myoclonic jerks and jitteriness were noticed and video EEG monitoring started. Upon analysis of video- EEG, myoclonic seizures and spasms were reported showing asymmetry in the amplitude of ictal EEG. MRI was recommended and performed to explain focal EEG findings, and a large brain left temporal lobe malformation was seen.\u0000\u0000\u0000CONCLUSIONS\u0000Spasms in the form of seizures are rarely reported in the neonatal period. Their recognition has to lead to urgent brain imaging study to look for the underlying cause and to implement timely, appropriate corrections in the treatment strategy. Although brain malformations can have many causes, taking careful antenata/, perinatal and family history has ruled out many usual etiologies. Materna/ alcohol consumption during pregnancy may potentially have contributed to the condition.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69886725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for premature aging in childhood cancer survivors.","authors":"M. Krawczuk-Rybak, Eryk Latoch","doi":"10.34763/devperiodmed.20192302.97103","DOIUrl":"https://doi.org/10.34763/devperiodmed.20192302.97103","url":null,"abstract":"Over the last decades, the overall survival rate for childhood cancer has increased from 20% to 80%, which is the result of advances in treatment Nevertheless, most data from the international registers of childhood cancer survivors (CCS) stress that this population of patients is at high risk for late sequelae and their biologica/ aging starts earlier in life. Anticancer therapy (chemotherapy, radiotherapy, surgery, immunotherapy) affects the intracellular processes leading to the chronic deterioration of organ function and premature senescence. The present review focuses on the late effects of anticancer treatment on various human organs that may lead to premature aging.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69887232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrition of infants and young children in Poland - Pitnuts 2016.","authors":"H. Weker, M. Barańska, A. Riahi, M. Strucińska, M. Więch, G. Rowicka, H. Dyląg, W. Klemarczyk, A. Bzikowska, P. Socha","doi":"10.34763/devperiodmed.20172101.1328","DOIUrl":"https://doi.org/10.34763/devperiodmed.20172101.1328","url":null,"abstract":"The study evaluating the feeding practices and the nutritional status of children aged 5 to 36 months in a general, Polish, representative population (n=1059) was carried out from May to July 2016. The aim of this study was to evaluate the feeding practices in children aged 5 to 36 months with regard to models of safe nutrition on the basis of the outcome of the population study performed in 2016. The data obtained show that the feeding practices in children in their first year of life do not meet the guidelines presented in the model of safe nutrition, particularly in matters of timing of complementary feeding introduction and food choice. The analysis of nutrient profile in toddlers' diets indicated the differentiated energy and protein intake is significantly higher than population norms (EAR/AI). It is necessary to modify the nutrition of infants and young children through a better selection of products. Nutritional practice should always be monitored and modified according to the model of safe nutrition as part of medical nutritional counselling. More educational efforts are required to increase the awareness of the relation between the diet and nutritional status of young children among healthcare professionals.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69885939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal mortality and morbidity of growth restricted fetuses and newborns (own experience) - first report.","authors":"K. Pankiewicz, T. Maciejewski","doi":"10.34763/devperiodmed.20172101.2934","DOIUrl":"https://doi.org/10.34763/devperiodmed.20172101.2934","url":null,"abstract":"AIM\u0000to evaluate the outcome of pregnancies complicated by fetal growth restriction with particular emphasis on the factors (fetal and maternal) related to perinatal mortality and morbidity of the fetus and newborn.\u0000\u0000\u0000MATERIAL AND METHODS\u0000Retrospective analysis of the documentation of 53 women admitted with the diagnosis of fetal growth restriction based on ultrasound examination (fetal biometry and fetal vessel Doppler abnormalities). 38 (71.7%) patients were referred to our department with the diagnosis of fetal growth restriction, whereas 15 (28.3%) cases were diagnosed in our hospital. 32 (60.4%) women were referred to our department by their main obstetrician, 13 (24.5%) by other hospitals and 8 (15.1%) came to triage because of worrisome symptoms. The patients were divided into 2 groups according to the presence of fetal/neonatal complications: the first group (n=14) - with complications (defined as one or more of the following: stillbirth, neonatal death, respiratory distress syndrome (RDS), intraventricular haemorrhage (IVH) Grade III or IV , necrotic enterocolitis (NEC), proven neonatal sepsis or bronchopulmonary dysplasia (BPD)) and the second one (n=39) - without severe complications.\u0000\u0000\u0000RESULTS\u0000Gestational age at diagnosis and at delivery was lower in the first group (28.5 weeks vs. 32.15 weeks, p=0.003 and 29.2 weeks vs. 32.8 weeks, p=0.0004). Female fetuses predominated in the second group (64.1%), whereas male fetuses in the first group (64.3%). In both groups the majority of patients delivered by cesarean section (92.9% vs. 97.4% p=0.44). Birth weight was significantly lower in the first group (774g vs. 1416g, p<0.0001). Perinatal morbidity (severe neonatal complications) occurred in 14 (26.4%) cases. The fetal and newborn perinatal mortality rate in the studied group was 13.19% (in comparison to 0.6% for the entire population of pregnant women in Poland).\u0000\u0000\u0000CONCLUSIONS\u00001. Gestational age (at diagnosis and at delivery) and birth weight are the most important prognostic factors related to the adverse outcome in the management of fetal growth restriction. 2.The most common mode of delivery for fetuses with growth restriction is the cesarean section. 3. Early detection of fetal growth restriction in routine perinatal care seems to be insufficient. 4. Fetal and newborn perinatal mortality and morbidity rates in fetal growth restriction are still high and the management of such pregnancies should take place in reference obstetric units, where detailed diagnostics, monitoring and treatment of fetal and neonatal complications can be performed.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69885948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body weight and quality of life among adolescents in krakow.","authors":"Agnieszka Magiera, E. Sochacka-Tatara, A. Sowa, R. Jacek, A. Pac","doi":"10.34763/devperiodmed.20182202.160170","DOIUrl":"https://doi.org/10.34763/devperiodmed.20182202.160170","url":null,"abstract":"AIM\u0000The aim of this study was to assess the relationship between body weight and the quality of life among adolescents in Krakow, Poland.\u0000\u0000\u0000MATERIAL AND METHODS\u0000The study comprised 1291 pupils - 632 girls and 659 boys from 17 Krakow middle schools. Their quality of life (QoL) was assessed by means of the Polish version of the KIDSCREEN-27 questionnaire. Five dimensions of QoL were analyzed as low, average and high QoL according to Polish cut-off points. The body mass index (BMI) of the adolescents was classified as underweight, normal weight, or excessive weight according to Polish growth charts.\u0000\u0000\u0000RESULTS\u0000Low QoL was observed significantly more often in girls than in boys. Excessive weight among both girls and boys was found to be a risk factor for low QoL in the \"Physical Well-being\" dimension as compared to normal weight adolescents. Additionally, boys with excessive weight had a two-fold higher risk of low QoL in the \"Social Support & Peers\" dimension (OR=2.00; 95 %CI:1.14-3.50). Underweight was associated with higher risk of low QoL in the \"Physical Well-being\", \"Autonomy & Parents\", and \"Social Support & Peers\" dimensions, but only among boys.\u0000\u0000\u0000CONCLUSIONS\u0000Both, underweight and excessive weight were associated with low QoL. Excessive weight in youth was linked mainly with lower physical well-being. Underweight was a predictor of low QoL only among boys in the dimensions related to physical health, as well as relations with family and peers.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69886331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of the release of exogenous nitric oxide on the responses of the pregnant human myometrium to oxytocin.","authors":"B. Modzelewska, T. Kleszczewski, A. Kostrzewska","doi":"10.34763/devperiodmed.20182204.301307","DOIUrl":"https://doi.org/10.34763/devperiodmed.20182204.301307","url":null,"abstract":"Currently there is insufficient evidence to support the routine administration of nitric oxide donors in the treatment of threatened preterm labor. An understanding of the role that nitric oxide plays in the management of threatened preterm labor may lead to more effective treatment and prevention. This is why the aim of our study was to examine the involvement of exogenous nitric oxide release in regulating responses of the human pregnant myometrium to oxytocin. Biopsies of human myometrial tissue during pregnancy were obtained from 8 pregnant women, aged 21-35 years. The responses of the specimens to oxytocin in the absence and presence of a DETA/NO were recorded under isometric conditions. Preincubation with exogenous nitric oxide significantly (p<0.001) attenuated the contractile response of the uterine strips to oxytocin in concentrations higher than 10 -8 mol/L. The inhibition of nitric oxide synthesis alone or in combination with DETA/NO incubation did not significantly change the oxytocin contractile effect in the concentration-response curve. Moreover, there was no significant variation in the mean value for log EC 50 for oxytocin between the group with oxytocin alone and other groups. We present evidence in support of the hypothesis that continuous nitric oxide supply to the human pregnant myometrium environment attenuates its response to oxytocin but only when endogenous production of nitric oxide is not impaired.","PeriodicalId":35058,"journal":{"name":"Medycyna wieku rozwojowego","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69886594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}