J. Dissemond, P. Al Ghazal, K. Herberger, J. Schaller, A. Strölin
{"title":"Significant Exacerbation of Darier's Disease and Pregnancy","authors":"J. Dissemond, P. Al Ghazal, K. Herberger, J. Schaller, A. Strölin","doi":"10.31579/2578-8949/044","DOIUrl":"https://doi.org/10.31579/2578-8949/044","url":null,"abstract":"Darier's disease, also known as keratosis follicularis or Darier-White disease, is an autosomal dominant inherited condition. The disease usually has its onset in the teenage years, meaning it co-exists with the years of fertility in women. The potential dermatological and obstetric implications of Darrier's Disease, especially when it involves the groin and vulva, have not been well reported. We report a case of Darier's Disease associated with multiple antibiotic resistant folliculitis involving skin of the breasts, groin, vulva and perineum that precluded safe vaginal delivery.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116480679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial:Importance of Stable, Efficient and Safer (Nano-) Emulsions for Topical Application: Case of a New Promising Cosmetic Formulation containing a Grape Extract against Premature Skin Aging","authors":"F. Menaa, Barkat Ali Khan","doi":"10.31579/2578-8949/048","DOIUrl":"https://doi.org/10.31579/2578-8949/048","url":null,"abstract":"Many innovative cosmetics are nowadays based on the concomitant use of ingenious materials (e.g. conventional or innovative emulsions, nanoparticles for deeper skin penetration) and plant extracts, encapsulated in them, exerting strong anti-oxidant properties enough to prevent premature skin aging and/or whitening properties, thereby capable of satisfying populations with physiological or pathological skin pigmentation [1-4]. However, the high cost related to the design and development of such products as well physical-chemical stability issues encountered in most of the considered “final products” represent few of the most important limitations for safer efficacy in translational medicine","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115794023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevention of Chronic Wound Infection in Clinical Practice","authors":"N. K. Tepeš","doi":"10.31579/2578-8949/043","DOIUrl":"https://doi.org/10.31579/2578-8949/043","url":null,"abstract":"The notion of prevention includes all and spreading is halted. For an efficient implementation of p patient and treatment, phases of phys pathophysiological features of the chronic","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125892084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on “The Effects of Probiotics on Immune Regulation, Acne and Photoaging”","authors":"M. Kober","doi":"10.31579/2578-8949/040","DOIUrl":"https://doi.org/10.31579/2578-8949/040","url":null,"abstract":"","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115235538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expanding Dermatologists view with Fluorescence and Thermograph","authors":"H. Buzzá","doi":"10.31579/2578-8949/039","DOIUrl":"https://doi.org/10.31579/2578-8949/039","url":null,"abstract":"","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133994643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transdermal diffusion of xenon from lipophilic solution of capric triglyceride and from water","authors":"Collin Jared, Diego Luis, J. Noah, Benjamin Dylan","doi":"10.31579/2578-8949/037","DOIUrl":"https://doi.org/10.31579/2578-8949/037","url":null,"abstract":"Aim: The purpose of the study was to characterize transdermal delivery of xenon through rat skin from a lipophilic solution and from water. Methods: Sections of skin were obtained from adult rats (n=12) and were placed into static Franz diffusion cells for 24 h. Xenon diffusion coefficients were determined for diffusion from a lipophilic solution (n=6) and from water (n=6) to phosphate buffered saline (PBS) through skin and for diffusion from a lipophilic solution to PBS through a phase boundary in the absence of skin (n=6). Results: Xenon flux (JXe) through skin from the lipophilic solution was 0.036 mg/hour×cm2 and permeability coefficient (Kp) was 0.003 cm/h; JXe through skin from water was 0.029 mg/h×cm2 and the Kp was 0.002 cm/h. Total time for xenon diffusion through skin from lipophilic solution and from water was ~2 h. Conclusion: The study presents the first characterization of xenon diffusion through rat skin from multiphase solutions to PBS. These data may be useful for the development of xenon-rich pharmaceutical products for external use.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128693782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sex Hormones Production in Both Genders Skin Diseases","authors":"E. Nicholas","doi":"10.31579/2578-8949/038","DOIUrl":"https://doi.org/10.31579/2578-8949/038","url":null,"abstract":"The skin is the largest organ in the body constituting 15% of the total body weight. It is therefore paramount to address skin diseases. Of major importance in the etiopathogenesis and pathophysiology of many of these diseases is the gender difference in the skin. Studies on endocrine effects on the skin have revealed that several important physiologic activities of the skin are either partly or wholly under the control of hormones secreted by different endocrine glands.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130388231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Segmental Defects in Peripheral Nerves Xenotransplantation","authors":"R. William","doi":"10.31579/2578-8949/036","DOIUrl":"https://doi.org/10.31579/2578-8949/036","url":null,"abstract":"Segmental defects in peripheral nerves that cannot be sutured directly require the use of nerve grafts. The ideal option for repair is nerve auto grafting, but there are some obvious disadvantages related to its use, such as lack of availability and donor site morbidity. The next step to consider for reconstruction is the use of nerve allografts, but they are also limited for clinical use, and they present with the added problem of graft rejection. Considering these limitations to the use of nerve autografts and allografts, clinical surgery research has turned to nerve xenotransplantation, which offers a potentially unlimited source of donor nerves.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122789645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toxic Epidermal Necrolysis (TEN) the Laser Resurfacing Approach: A Case Report","authors":"G. Francisco","doi":"10.31579/2578-8949/035","DOIUrl":"https://doi.org/10.31579/2578-8949/035","url":null,"abstract":"","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124860486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Napolitano, T. Cirillo, C. Patruno, P. Gisonni, M. Megna, N. Balato
{"title":"Case report : Use of Phototherapy for Acrodermatitis Continua of Hallopeau in Childhood: Case Report and Review of the Literature","authors":"M. Napolitano, T. Cirillo, C. Patruno, P. Gisonni, M. Megna, N. Balato","doi":"10.31579/2578-8949/033","DOIUrl":"https://doi.org/10.31579/2578-8949/033","url":null,"abstract":"A 6-year-old girl presented to our attention with a 7-month history of erythema and pustules on the distal portion of her left first finger, which deeply affected the beginning of her scholar activity. On examination, her digit was swollen, markedly erythematous, and littered with several small pustules; nail was strikingly dysmorphic. The other digits showed variable degree of onychodystrophy (Fig. 1A). There were neither prior history of psoriatic lesions nor familiarity for psoriasis. Microscopic and cultural examination did not show any microbiological infection. Histological sample showed psoriasiform hyperplasia, with a collection of granulocytes in the context of parakeratosis as well as in the intraepithelial area (Munro-like microabscesses), and focal spongiosis with absent granular layer. The dermis showed increased vascularity within the dermal papillae. Ultrasonography highlighted cutaneous and sub-cutaneous thickness increase with intra-articular synovial effusion (Fig. 1C); at color Doppler, increase of vascularization was present in sub-cutaneous tissue (Fig. 1D). On the basis of these findings, a diagnosis of acrodermatitis continua of Hallopeau (ACH) was performed. Past treatment only consisted of topical steroids. A cycle of clobetasol 0.05% ointment under occlusion and narrow band UVB (310 -311 nm) was prescribed for 30 days. The improvement observed at follow-up visit (Fig. 1B), increased after the subsequent 2 months of therapy, without relapse. The young patient is still under treatment and no relapse was notead at 3.5 months follow-up.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114716479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}