{"title":"Infectious Dermatoses are Common in Primary Health Care Setting in Côte d’Ivoire","authors":"M. Wesley, G. Kenneth, I. Connor, R. William","doi":"10.31579/2578-8949/015","DOIUrl":"https://doi.org/10.31579/2578-8949/015","url":null,"abstract":"Background: Infectious dermatoses are common in many countries in Africa. These skin conditions mostly caused by bacterial, fungal, viral, and parasitic agents are frequent in primary health care setting. These are favored by poverty that deprives individual of the freedom to satisfy basic needs and rights: this includes freedom to enjoy clean water or sanitary facilities, and good accommodations or remedies for illnesses. Objective: This study was conducted to show the frequency of infectious dermatoses in a primary health center in Côte d’Ivoire. Methods: It was retrospective and descriptive study conducted in the community health care center in Yopougon Attié from 2006 to 2010. Results: About 3.392 patients out of 22.609 (15% of cases) were admitted for dermatoses during a period of 5 years. Only 203 patients got accurate diagnosis for dermatoses. Sixty three patients were males (32.7%) and 135 were females (67.5%). The sex ratio was 2.08 in favor to females. Patients’ age ranged from 6 months to 59 years with average age of 27 years ±2.2. Patients from age group between 15 and 29 years were the most concerned (46.4%), followed by the age group under 14 years (25.8%). Illiterate or primary and secondary education patients (79.9%) were mostly observed. Adverse socio-cultural practices were performed in 56.7% of cases. We observed infectious dermatoses in 92.12% of cases (194/203) infections due to bacterial agents were most observed in 42.6% of cases, followed by viral agents in 31.95% of cases. We found HIV positive patients in 5.7% of cases. Conclusion: Infectious dermatoses are common in primary health care setting in Côte d-Ivoire and can be treated by any physician. But, a dermatological training is needed to improve primary health care practitioners’ dermatological skills for clear diagnosis and appropriate treatment in order to reduce their incidence and prescription costs.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127400635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lesions of Cutaneous Leishmaniasis Elicited after Local Trauma: A Case Report","authors":"Benjamin Dylan, H. Wyatt, C. Ricardo, M. Troy","doi":"10.31579/2578-8949/008","DOIUrl":"https://doi.org/10.31579/2578-8949/008","url":null,"abstract":"In Brazil there is an average of 30,000 cases of Cutaneous Leishmaniasis reported annually, and around the world it happens for about each 20 seconds. Although there are still opportunities to contribute with studies about this disease; supporting the medical community, especially dermatologists, mainly because of the necessity of knowing that a relatively simple procedure can result such a relevant trauma. Female patients presented erythematous plaque in the limb. Lesion appeared days after laser sessions for hair removal. Biopsy showed amastigotes forms and positive culture. After unsuccessful treatment it was managed with N-methyl glucamine 20 mgSbV/kg/day, during 20 days, there was significant improvement of the clinical picture. This study aims to present a case report of Cutaneous Leishmaniasis initiated after local trauma. Literature reports describe primary or secondary lesions of Cutaneous Leishmaniasis elicited after a local trauma. The mechanism used in order to explain these events was the migration of infected macrophages induced by cytokines. Similar events have also been reported as part of the locus minoris resistentiae concept that comprises situations in which microorganisms have a tendency to settle at places of weakened resistance. Considering that Leishmaniasis lesions are usually developed in promastigote forms are inoculated by the Phlebotominae, in this case it was noted that the infection has been favored by the local trauma.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128769112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Despite Genetic and Proteomic Arguments, the Three Common Variants of NOD2/ CARD15 Genes: Pemphigus Foliaceus","authors":"Chao An","doi":"10.31579/2578-8949/009","DOIUrl":"https://doi.org/10.31579/2578-8949/009","url":null,"abstract":"Background: Knowledge about the pathogenesis of Pemphigus Foliaceus (PF), an autoimmune disorder of the skin natural barrier, is still modest. Genetic susceptibility factors have been widely studied, while environmental factors remain still ambiguous. NOD2/CARD15 gene encodes an intracytoplasmic receptor involved in recognition of microbial components and NF-κB inflammatory signaling pathway. Three common CD-associated variations (R702W, G908R and 1007fs) cause a \"loss of function\" of the molecule and lead to a chronic inflammation in the intestinal epithelial barrier. The aim of this study is to analyze NOD2/CARD15 gene polymorphisms in Tunisian endemic PF. Methods and Results:A case-control study including 79 PF patients and 160 controls was conducted using PCR-RFLP and direct sequencing. Our results showed that the three SNPs are not polymorphic in both patients and controls (allelic frequencies were 0.63% vs 1.25%, 0.63% vs 1.87% and 0% vs 0.62%, respectively). There was no association of mutant alleles with the disease. Conclusions: Our results suggest that the three common variants of NOD2/CARD15 gene are not involved in susceptibility to Tunisian PF. The alteration of the molecule's functionality caused by these mutations seems to not interfere with the development of the disease.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128183760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luke Jackson, E. Nicholas, R. Mason, Landon D. Owen
{"title":"Chemical Peels: Wound Treatment for up to Three Months Post Peel Recuperative Phase.","authors":"Luke Jackson, E. Nicholas, R. Mason, Landon D. Owen","doi":"10.31579/2578-8949/005","DOIUrl":"https://doi.org/10.31579/2578-8949/005","url":null,"abstract":"The cutaneous ageing process whether skin laxity, facial wrinkles, ageing pigmantory spots is a continuous process which is invariably difficult to stop, despite the recent advances in science and medicine. Moreover, to combat the signs of ageing, chemical peels may be used to help ameliorate the scars, to destroy premalignant and/or malignant lesions, unsightly pigmentation etc. The treatment modalities used to produce a controlled injury are dermabrasion, chemical peels and photoepilation (laser and intense pulse light) therapy. Only if the injury is in the proper tissue plane can the desired result be achieved. If too superficial, the results will be disappointing. If too deep, the results can be catastrophic. The chemical peeling creates a controlled injury in an attempt to correct a particular problem. Historically, various chemical peels used such as phenol, trichloroacetic acid as single agent or in combination. Recently, newer agents have been introduced into the world of chemical peeling. These newer agents are used in combination for resistant hyperpigmentation or combined with intense pulse light microdermabrasion for acne scarring to achieve satisfactory results.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122145345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Infection of Acrodermatitis Chronica Atrophicans Herxheimer by Borrelia Affzelii","authors":"L. Owen, J. Noah, Benjamin Dylan","doi":"10.31579/2578-8949/004","DOIUrl":"https://doi.org/10.31579/2578-8949/004","url":null,"abstract":"Acrodermatitis Chronica Atrophicans Herxheimer (ACA) is a tick-born disease due to infection by Borrelia afzelii, the major vector organism is Ixodes rhicinus. We report on a 48-year-old male patient who developed extensive livid-erythematous fibrosclerotic symmetric plaques associated with hyperpigmented widely distributed lesions within the tension lines, and acrocyanosis. The diagnosis of ACA has been confirmed by histopathologic examination of a skin biopsy and laboratory investigations with positive IgG and IgM immunoblots. The patient was treated by intravenous ceftriaxone resulting in partial remission of cutaneous and extracutaneous symptoms.","PeriodicalId":350109,"journal":{"name":"Dermatology and Dermatitis","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130909341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}