Current Research in Complementary & Alternative Medicine最新文献

{"title":"Pumpkin Halwa Pudding: Not Just Dessert, A Bioactive Powerhouse to Boot as Well","authors":"Sharadendu Bali, Randhir Singh, Assad Usman","doi":"10.29011/2577-2201.100219","DOIUrl":"https://doi.org/10.29011/2577-2201.100219","url":null,"abstract":"Pumpkin (Cucurbita Maxima) is a famous member of the Cucurbiteacea family, which is eaten both as a vegetable meal and as a dessert. The dessert form prepared in India is a type of pudding, called Halwa , made by cooking the pumpkin pulp in ghee (clarified butter) and milk. High in nutritional content, halwas also possess the capability to efficiently deliver the phytochemicals present in the basic foods from which these are made. This phytochemical delivery is accomplished by ghee and milk proteins, which behave as phytochemical carriers","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139198520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Water Extract of Dendropanax morbiferus Ameliorates Scopolamine-Induced Cognitive Impairment in Mice","authors":"In-Su Kim, Shin-Young Park, Yeon-gil Kwak, Dong-Kug Choi","doi":"10.29011/2577-2201.100217","DOIUrl":"https://doi.org/10.29011/2577-2201.100217","url":null,"abstract":"Dendropanax morbiferus (DM) has been used in oriental medicine for various diseases such as inflammation, diabetes, and cancer. Several effects of DM have been known by researchers, but there have been no reports of the effects of cognitive impairment. Therefore, in this study examined anti-amnesic activity with its potential mechanism of action using scopolamine induced amnesic C57/BL6N mice. The effect of DM on cognitive impairment improvement on scopolamine-induced memory impairment in mice was evaluated using passive avoidance test and y-maze test. Besides, ELISA and Western Blot analysis were performed to examine several molecular markers such as inflammatory markers, oxidative stress markers, and BDNF signaling that occur in memory damage caused by scopolamine. The administration of DML (100 or 200 mg/kg, p.o.) significantly ameliorated the scopolamine-induced cognitive impairment in the passive avoidance task, the Y-maze. Also, the administration of DM suppressed increased brain inflammatory markers (iNOS, cox-2, IL-1α, IL-6, IFN-α), lipid peroxidation (MDA), and BDNF expression. Current research suggests that DM improves cognitive dysfunction by regulating molecules caused by neuroinflammatory and oxidative damage leading to nerve damage and may have therapeutic potential for cognitive dysfunction.","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"621 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139245075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-Applied Acupressure and Online Qigong for Chronic Fatigue Post Covid19 (ACUQiG) - Design and Methods of a Randomized Controlled Trial","authors":"","doi":"10.29011/2577-2201.100214","DOIUrl":"https://doi.org/10.29011/2577-2201.100214","url":null,"abstract":"","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"17 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139277962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alpinia galanga Extract IncreasesA lertness, Focus, and Energy While Lowering Fatigue and Daytime Sleepiness with Four Weeks Supplementation: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study in Human Subjects","authors":"Mohan Muttanahally Eraiah, Mamatha Kundapur, Lincy Joshua, Jestin V Thomas","doi":"10.29011/2577-2201.100209","DOIUrl":"https://doi.org/10.29011/2577-2201.100209","url":null,"abstract":"While Lowering Fatigue and Daytime Sleepiness with Four Weeks Supplementation: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study in Human Subjects. Curr Res","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139312891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Grounding and Skin Repair: The Power of DC Energy","authors":"Laura Koniver","doi":"10.29011/2577-2201.100097","DOIUrl":"https://doi.org/10.29011/2577-2201.100097","url":null,"abstract":"Our earth provides a natural direct current (via a DC global electrical grid) that provides multiple health benefits to the human body — an exciting field of research which is just beginning to emerge. Many of the organ systems of the human body, including the cardiac system, musculoskeletal system, and central nervous system, utilizes a DC energy current to operate. Skin, in particular, uses a small DC electrical field to guide cell migration and wound healing after injury, a process known as electrotaxis. Recent research into exogenously applied DC energy has shown promising results in boosting keratinocyte recovery and improved wound healing, which gives rise to the possibility of applying the earth’s DC energy field directly to the skin (a healing modality known as grounding) to support skin health. There are several health benefits from grounding that may directly boost the skin’s ability to heal, including improving circulation to the skin (which boosts oxygen and nutrients as well as removes metabolic waste) and improved keratinocyte repair in both healthy keratinocytes and damaged keratinocytes. Indirectly, grounding may also protect skin by deepening sleep, which has been found to improve collagen integrity and may help protect skin volume, firmness and elasticity, preserving it’s strength. This is an exciting area of research that has interesting applications not only to help treat dermatologic conditions and to improve wound healing, but also in the anti-aging and cosmetic industry as well. More research on the health benefits of DC energy, and in particular receiving DC energy through direct contact with the earth’s global electrical DC energy grid via grounding, is much needed.","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"50 11-12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133567442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioavailability Study of Maxicuma Capsules Versus Micronized Curcumin Capsules as A Single Oral Dose in Fasted Healthy Adult Human Subjects","authors":"M. Rachchh, R. Gokani, Hetal Patel, Jainik Khamar, Apurva Patel","doi":"10.29011/2577-2201.100091","DOIUrl":"https://doi.org/10.29011/2577-2201.100091","url":null,"abstract":"Aim: The purpose of this study is to evaluate and compare the amount of free Curcumin in the human blood plasma after administration of three Capsules of Maxicuma 500 mg and three Capsules of Micronized Curcumin 95% each 500 mg as single dose in fasted healthy adult human subjects. The results of the study are also compared with plasma concentration of free Curcumin by Standard Curcumin as reported in the literature [17]. Methodology: Comparative bioavailability of free curcumin for three Capsules of Maxicuma 500 mg and three Capsules of Micronized Curcumin 95%, (500) mg was evaluated in an open label, non-randomized, two-treatment, two-period, two-group crossover study after single oral dose administration in 14 fasted healthy adult humans. The free Curcumin was determined along with pharmacokinetic parameters such as Cmax, AUC0-t, T1/2, Ke, Tmax, %AUC extra, n points, Ke_first and Ke_last. Linear & Semi log graphs were plotted with the help of SASR ® . In addition, the total Curcuminoids (Comprising Curcumin, Bis-Demethoxy curcumin, Demethoxy curcumin & Tetra hydrocurcumin) after reaction with mixture of glucuronidas3 + sulphatase enzyme was estimated in plasma using validated LC-MS-MS method. Results: Data from the study reveals that the maximum measured plasma concentration of free Curcumin was 195.196 ng/mL for Maxicuma and 81.270 ng/mL for Micronized Curcumin 95%. The times where maximum plasma concentration of free Curcumin achieved for the Maxicuma and Micronized Curcumin 95%, were 3.129 hours and 4.750 hours respectively. Conclusion: Maxicuma composition was 3.11 fold more bioavailable, in terms of free Curcumin level, as compared to Micronized Curcumin 95%. As it is known from the literature that, micronization enhances the bioavailability by 9 folds, one can conclude that Maxicuma was 66.47(3.11/0.4 x 0.95 x 9) times more bioavailable in terms of total Curcuminoids compared to Standard Curcumin extract powder 95% and based on the literature study, provides 172 times more bioactive free Curcumin when compared to Standard Curcumin 95%.","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130703787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Scent-Sational Approach to Patient and Staff Well-Being","authors":"","doi":"10.29011/2577-2201.100090","DOIUrl":"https://doi.org/10.29011/2577-2201.100090","url":null,"abstract":"","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126448192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lysozyme – An Underexploited Molecule with High Therapeutic Potential but of Little Interest to the Pharmaceutical Industry","authors":"","doi":"10.29011/2577-2201.100088","DOIUrl":"https://doi.org/10.29011/2577-2201.100088","url":null,"abstract":"","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124570233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aromatherapy: Implementation in a French Comprehensive Cancer Center","authors":"Bénédicte Leclere Condis, Florence Jay Runner, Julien Beaurenault, Myriam Aitichou, B. Favier, I. Delzano, C. Bigeard, Agnès Arquillière, F. Veyret, Christelle Baptista-Goux, Isabelle Ulrich, B. Mastroianni","doi":"10.29011/2577-2201.100086","DOIUrl":"https://doi.org/10.29011/2577-2201.100086","url":null,"abstract":"Continuous advances in cancer care are accompanied by the necessity to better support patients, and implementation of new alternatives beyond the scope of conventional medicine are regularly required. Integrative oncology, besides conventional specific care, provides a large access to complementary therapies guiding patients to become actors before, during, and after cancer treatment","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116503343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation of Acupoints on Standardized Therapeutic Protocols: An Example of Successful Integration between Eastern and Western Medicine","authors":"M. Vanzini, M. Gallamini, L. Calzà, L. Lorenzini","doi":"10.29011/2577-2201.100085","DOIUrl":"https://doi.org/10.29011/2577-2201.100085","url":null,"abstract":"Acupuncture has not yet gained uniform acceptance among Western medicine (WM) practitioners, despite its increasing use in healthcare facilities and its growing popularity with the general public to treat a wide range of clinical conditions. Anyone who works with acupuncture or traditional Chinese medicine (TCM) is acutely aware of the complexity of achieving a true integration of these Eastern practices into Western medicine, a process hampered by the difficulty in finding a unique biological explanation for the established efficacy of TCM therapies. Despite such difficulty, acupuncture application is expanding, and clinical evidence is growing rapidly. We submit that it is just about time to start integrating the two worlds bridging the gap between them. Object: Our work was therefore aimed at proposing a combination of the western criterion of applying standardized therapeutic protocols and of the eastern principle of restoring the healthy energy flow throughout the","PeriodicalId":350008,"journal":{"name":"Current Research in Complementary & Alternative Medicine","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133782420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}