MedPulse International Journal of Pediatrics最新文献

A study efficacy of pyridoxine in early-onset idiopathic intractable seizures in pediatric patient at tertiary health care center 吡哆醇治疗三级卫生保健中心儿童早发特发性难治性癫痫的疗效研究

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/1014937

Jagadish N Bhadbhade

{"title":"A study efficacy of pyridoxine in early-onset idiopathic intractable seizures in pediatric patient at tertiary health care center","authors":"Jagadish N Bhadbhade","doi":"10.26611/1014937","DOIUrl":"https://doi.org/10.26611/1014937","url":null,"abstract":"Background: Pyridoxine is used for management of seizure disorder in three settings viz., seizures that respond to pyridoxine and require life-long supplementation with therapeutic doses of pyridoxine, pyridoxine dependent seizures Aims and Objectives: study Efficacy of Pyridoxine in Early-Onset Idiopathic Intractable Seizures in pediatric patient at tertiary health care center. Methodology: This was a cross-sectional study carried out in the patients of Early-Onset Idiopathic Intractable Seizures in pediatric patient during the one year period i.e. June 2017 to June 2018, there were 64 pediatric patients with Idiopathic Intractable Seizures were enrolled for the study. All details of the patients like Age, sex etc. was noted. All the patients were undergone EEG testing. Out of 64 patients Group A received 30 mg/kg/day pyridoxine with 4 mg/kg/day of oral prednisolone Group B received 4 mg/kg/day of oral prednisolone and 14, 15 randomly. The outcome of patients like episodes of seizure etc. was noted after 1 month of treatment. The statistical analysis was done by Chi-square test and analyzed by SPSS 19 version software. Result: In our study the average age in both the group was comparable with each other i.e. 3 ±1.21Yrs. and 3.52±1.31 Yrs. (p>0.05, t=1.12,df=62). The ratio of Male and Female was 2.9: 1 and 1.90: 1 was comparable with each other (X2=0.29, df=1,p>0.05). Complete seizure freedom was found in 34.38% and 9.38%; >50% seizure reduction but not complete cessation in 40.63% and 28.13%; <50% seizure reduction in 25.00% and 62.50% respectively in Group A and Group B which was statistically significant (X2=10.44, df=2,p<0.005). EEG findings Normal in 37.50% and 12.50%, Decreased Epileptiform discharges in 46.88% and 31.25%, Persistent Epileptiform discharges in 15.63% and 56.25% respectively in Group A and Group B this observed difference was statistically significant (X2=12.35, df=2,p<0.002) Conclusion: It can be concluded from our study that the patients who received the pyridoxine treatment improved much as compared to not received so the role of pyridoxine in the treatment of intractable seizure should not be underestimated. Key Word: Pyridoxine, Early-Onset Idiopathic Intractable Seizures, EEG Address for Correspondence: Dr. Jagadish N Bhadbhade, Assistant Professor, Department of Paediatrics, Vedaantaa Institute of Medical Sciences, At Saswand, Dhundalwadi, Talk. Dahanu, Dist. Palghar401602, Maharashtra, INDIA. Email: jagadish_bhadbhade@yahoo.co.in Received Date: 29/01/2019 Revised Date: 19/02/2019 Accepted Date: 14/03/2019 DOI: https://doi.org/10.26611/1014937 INTRODUCTION Pyridoxine is used for management of seizure disorder in three settings viz., seizures that respond to pyridoxine and require life-long supplementation with therapeutic doses of pyridoxine, pyridoxine dependent seizures (PDS, MIM 266100); early-onset seizures responsive to pyridoxine but not requiring life-long pyridoxine supplementation, pyridoxine-responsive seizu","PeriodicalId":349984,"journal":{"name":"MedPulse International Journal of Pediatrics","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116909003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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A study of role of serum Zn and hemoglobin in the patients of simple febrile seizures at tertiary health care centre 血清锌和血红蛋白在三级卫生保健中心单纯热性惊厥患者中的作用研究

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/10141021

S. Patil, Kudlappa P Angadi, R. Anusha

引用次数: 0

Neonatal morbidity and mortality in post-term pregnancy in civil Hospital affiliated to B J Medical College, Ahmedabad, Gujrat 古吉拉特邦艾哈迈达巴德B J医学院附属民用医院足月妊娠新生儿发病率和死亡率

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/10141225

Manisha Ghoniya, A. Chauhan

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Assessment of clinical profile and radiological finding in cases of cerebral palsy 脑瘫病例的临床表现和影像学表现评估

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/10141925

Ramchandra Nagargoje

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A study of clinical profile and prevalence of Noro virus in acute Diarrhoea among children attending a tertiary care hospital 在三级保健医院就诊的儿童急性腹泻中诺如病毒的临床概况和流行情况的研究

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/1014919

K. Prasad, S. Krishna, A. Bobba, N. Sarath, AsProfessor

引用次数: 0

Thyroid profile in critically ill children and its effect on the clinical outcome 危重患儿甲状腺特征及其对临床预后的影响

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/10142123

Joewin Monteiro

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Maternal factors as determinants of low birth weight deliveries 母亲因素是低出生体重分娩的决定因素

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/10141015

K. Amit, D. Bang

{"title":"Maternal factors as determinants of low birth weight deliveries","authors":"K. Amit, D. Bang","doi":"10.26611/10141015","DOIUrl":"https://doi.org/10.26611/10141015","url":null,"abstract":"Background: Maternal factors are more influential in affecting neonatal birth weight through biological and nonbiological means. Some of the bio-social factors like maternal age, parity, height, weight, gestation, etc., have been postulated to determine the birth weight of a newborn. Aim: To know the association between maternal factors and low birth weight babies. Material and Methods: In this hospital based cross sectional analytical study 326 mother with their neonates were included. Maternal factors such as age, parity, haemoglobin, height, weight and body mass index were studied for their association with low birth weight neonates. Results: The association of low birth weight with inter pregnancy interval of less than 2 years was significant (p value<0.05). However, the association of low birth weight with parity was not significant (p value>0.05). The association of low birth weight with maternal height of <150cm, weight of less than 55 kg and Hb less than 10 gm/dl was highly significant (p value<0.05). Conclusion: Many of the risks factors responsible for LBW can be identified prior to pregnancy. For reducing the prevalence of LBW there is a need of sustainable practices to improve women’s nutritional status during childhood, adolescence and prior to pregnancy. Key Word: Low birth weight, maternal factors, body mass index, haemoglobin *Address for Correspondence: Dr. Kumar Amit, Senior Resident, Department of Paediatrics, Madhubani Medical College and Hospital, Madhubani -847212, Bihar, INDIA Email: amyfred89@gmail.com Received Date: 26/01/2019 Revised Date: 10/03/2019 Accepted Date: 07/04/2019 DOI: https://doi.org/10.26611/10141015","PeriodicalId":349984,"journal":{"name":"MedPulse International Journal of Pediatrics","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121301024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Study of various risk factors predisposing to hearing impairment in the new-born 新生儿听力障碍易感因素的研究

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/101411110

S. Khot, B. Shah

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Rare case report of Laurence-Moon-BardetBiedel syndrome 劳伦斯-穆恩-巴德比德尔综合征罕见病例报告

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/1014932

P. Divyashree, A ManuM, D RekhaT, B Dakshayani, Sarala Sabapathy

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Effect of type of anaesthesia in lower segment caesarean section on apgar score of new born babies: A comparative study 下段剖宫产麻醉方式对新生儿apgar评分影响的比较研究

MedPulse International Journal of Pediatrics Pub Date : 1900-01-01 DOI: 10.26611/10141018

Neeru Gupta, K. India., Naine Bhadrala, H. Multani

{"title":"Effect of type of anaesthesia in lower segment caesarean section on apgar score of new born babies: A comparative study","authors":"Neeru Gupta, K. India., Naine Bhadrala, H. Multani","doi":"10.26611/10141018","DOIUrl":"https://doi.org/10.26611/10141018","url":null,"abstract":"Background: To compare the effects of general anaesthesia and spinal anaesthesia on Apgar score in full term neonates born to elective caesarean section. Methods: The study was conducted on 90 healthy full term patients of ASA 1 and 2 category presenting for elective lower segment caesarean section (LSCS). 45 patients were given general anaesthesia and other 45 received spinal anaesthesia. The Apgar score was recorded at 1 minute and 5 minutes after birth. Results: Out of 45 mothers who received general anaesthesia, 38 (84.4%) gave birth to neonates having Apgar score less than or equal to 6 at 1 minute after birth and the remaining 7 neonates (15.6%) had Apgar score of more than 7. Out of 38 babies only one baby continued to have Apgar score of less than or equal to 6 at 5 minutes. On the other hand, out of 45 mothers who received spinal anaesthesia, only 15 mothers gave birth to babies having Apgar score less than or equal to 6 at 1 minute after birth out of which 14 improved at 5 minutes with Apgar score of more than or equal to 7. Conclusion: We conclude based on the study results that babies born by LSCS under general anaesthesia are at higher risk of having low Apgar score (Less than or equal to 6) at 1 minute after birth. Key Word: Caesarean Section, General Anaesthesia, Spinal Anaesthesia, Apgar score *Address for Correspondence: Dr. Neerupam Gupta, Department of Pediatrics, Govt. Hospital Sarwal, Directorate of Health services, Jammu, J and K -180015, INDIA. Email: neroped@gmail.com Received Date: 20/01/2019 Revised Date: 27/02/2019 Accepted Date: 07/04/2019 DOI: https://doi.org/10.26611/10141018 INTRODUCTION The choice of anaesthesia for obstetric cases has been traditionally influenced by patient and physician preferences. It can be performed under general or regional anaesthesia like spinal or epidural technique. The obstetric anaesthetist requires special training and skills to provide safe anaesthesia. The anaesthetic techniques and agents chosen should provide good anaesthesia and analgesia with minimal effects on fetomaternal well being. Although most patients undergoing caesarean section are young and healthy, they represent a high risk group of patients. Either of general and spinal anaesthesia is not ideal for caesarean section because each has advantages and risk to both mother and foetus. However the aim of anaesthetist is to choose the method which is safest and most comfortable for the mother, least depressive to the new born and which provides optimal working conditions for obstetrician1. Apgar score is the best parameter to assess the immediate condition of the baby.2,3 It is the first non invasive test done to the new born after birth. It is a bedside clinical method to assess the health of the new born immediately after birth and to determine the need of any resuscitative measures. The scores are taken at 1 and 5 minutes after birth. Of the two scores, the 5 minutes score is regarded as the better predictor of survival ","PeriodicalId":349984,"journal":{"name":"MedPulse International Journal of Pediatrics","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115860377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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