Turkiye parazitolojii dergisi最新文献

{"title":"Clinicopathological Assesment in Patients with <i>Enterobius vermicularis</i> Infection","authors":"Fatma Zeynep Özen,&nbsp;Gökçe Celep","doi":"10.4274/tpd.galenos.2023.02418","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2023.02418","url":null,"abstract":"<p><strong>Objective: </strong><i>Enterobius vermicularis</i> is a common gastrointestinal parasite. Acute appendicitis is one of the most common clinical conditions requiring surgical intervention. The coexistence of enterobiasis and acute appendicitis has attracted the attention of researchers for a long time. In this article, it is aimed to present the characteristics of enterobiasis cases detected in appendectomy specimens in a tertiary healthcare institution. In addition, it is aimed to reveal the differences by comparing the cases diagnosed with acute appendicitis without enterobiasis.</p><p><strong>Methods: </strong>All cases operated for acute appendicitis between January 1, 2008 and December 31, 2021 were retrospectively evaluated through the hospital registry system. The cases with histopathologically determined <i>E. vermicularis</i> were reviewed and a study group was formed. The control group consisted of patients diagnosed with acute appendicitis for reasons other than enterobiasis, matched with the study group in terms of age and gender. Complete blood count, C-reactive protein (CRP) ultrasonography evaluations were compared between the two groups.</p><p><strong>Results: </strong>During the study period, 3.650 appendectomy materials were examined; <i>E. vermicularis</i> was detected in 1.32% (n=48) cases, and acute appendicitis was present in 33.33% (n=16) of the cases. Lymphoid hyperplasia was the most common histopathological change in the study group (n=25; 52.08%). When compared to the control group, leukocyte, neutrophil, CRP, ultrasonographic appendix diameter values were found to be significantly higher in the control group, and the percentage of eosinophils in the study group (p<0.0001; p<0.0001; p<0.0001; p<0.0001; p=0.001; respectively).</p><p><strong>Conclusion: </strong>Enterobiasis is a common parasite especially in children. Rarely, it can be seen in patients with acute appendicitis. Histopathological evaluation is necessary to ensure a safe surgical procedure and to complete the treatment with anthelmintic drugs. Enterobiasis should be kept in mind in cases when the acute phase response is lower than expected.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"47 2","pages":"93-99"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Prevalence and Phylogenetic Characterization of <i>Enterocytozoon bieneusi</i> in Sheep in the Van Region","authors":"Muhammet Hasan Apaydın,&nbsp;Gamze Yetişmiş,&nbsp;Faruk Karabulut,&nbsp;Alparslan Yıldırım","doi":"10.4274/tpd.galenos.2022.76476","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2022.76476","url":null,"abstract":"<p><strong>Objective: </strong>In this study, we aimed to determine the prevalence of <i>Enterocytozoon bieneusi</i> in healthy sheep in Van province using molecular techniques and to reveal genotypes of the detected isolates.</p><p><strong>Methods: </strong>A total of 200 healthy appearance sheep comprise 38 male and 162 female, 32 preweaned, 38 postweaned lamb and 130 adult sheep from several farms in the Van region were included in the study between May and September 2021. Genomic DNA (gDNA) extractions were utilized on fecal samples collected from sheep by commercial kits, and <i>E. bieneusi</i> DNA was investigated by Nested polymerase chain reaction (PCR) amplifying ITS rRNA in the gDNA isolates. PCR products of the positive isolates were subjected to sequence analyze for genotyping and phylogenetic analyses of <i>E. bieneusi</i>.</p><p><strong>Results: </strong><i>E. bieneusi</i> DNA was determined in 16 out of 200 examined sheep fecal gDNA samples (8.0%) by Nested PCR. The highest <i>E. bieneusi</i> prevalence was determined in preweaned lambs with a rate of 18.8%. This was followed by postweaned lambs and adult sheep with a prevalence of 10.5% and 4.6%, respectively. The prevalence of the infection in males and females was 7.9% and 9.3%, respectively. All the ITS rRNA amplicons from 16 positive isolates were subjected to sequence analyses for genotyping and phylogenetic analyses. Sequence analyses revealed that all the isolates determined in sheep belonged to the BEB6 genotype and clustered in genogroup 2 of <i>E. bieneusi</i> with the BEB6 isolates from different hosts in several countries.</p><p><strong>Conclusion: </strong>Molecular epidemiological data on the prevalence of <i>E. bieneusi</i> in sheep in Turkey were obtained with this study and the common genotype was determined as BEB6 in the research area. The obtained data contribute to the molecular epidemiology and diversity of <i>E. bieneusi</i> in sheep.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"47 2","pages":"64-70"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9556326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of the COVID-19 Pandemic Process on the Incidence of Intestinal Parasites; Aydın Province Example","authors":"İbrahim Yıldız,&nbsp;Evren Tileklioğlu","doi":"10.4274/tpd.galenos.2023.22438","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2023.22438","url":null,"abstract":"<p><strong>Objective: </strong>The Coronavirus disease-2019 (COVID-19) pandemic, which started in our country in March 2020, has caused a sudden and dramatic change in our habits. As a result of the pandemic measures directly effective in the transmission of parasites, it has become important to investigate the possible effect of the COVID-19 pandemic process on the incidence of intestinal parasites.</p><p><strong>Methods: </strong>In order to examine the situation before and after the pandemic, all stool and cellophane tape test results examined from March 11, 2018 to March 11, 2022 in Aydın Adnan Menderes University Faculty of Medicine Parasitology Laboratory were evaluated retrospectively. The relationship between the socio-demographic characteristics of the cases, the distribution of the months and years of diagnosis and the prevalence of parasites were also evaluated.</p><p><strong>Results: </strong>Of the 13,036 stool samples examined, 67.42% belong to the pre-pandemic and 32.58% belong to the post-pandemic period. In total, 1.959 stool samples were positive for at least one parasite, of which 71.41% were from the pre-pandemic. <i>Blastocystis</i> spp. was the most frequently detected parasite both before (14.63%) and after the pandemic (12.59%). Of the 3.194 cellophane tape examined, 72.32% belonged to the pre-pandemic and 27.68% post-pandemic period, and <i>Enterobius vermicularis</i> eggs were detected in 246 (7.70%) of all. The majority of <i>E. vermicularis</i> positive samples (82.11%) were belonged to the pre-pandemic period. The number and positivity rates of stool and cellophane tape samples examined in the post-pandemic period showed a significant decrease (p<0.05).</p><p><strong>Conclusion: </strong>It was observed that the incidence of intestinal parasites decreased significantly during the COVID-19 pandemic. Important developments in terms of public health, such as measures such as social distance and quarantine during the pandemic process, increased sensitivity to personal hygiene, and informing the public through various tools during the pandemic, are thought to be the reason for the decrease in the prevalence of intestinal parasites.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"47 2","pages":"100-104"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9556328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution of <i>Toxocara vitulorum</i> in Cattle of Ağrı Region","authors":"Milad Torkamanian Afshar,&nbsp;Selahattin Aydemir,&nbsp;Hasan Yılmaz,&nbsp;Rahmi Yıldız,&nbsp;Fethi Barlık,&nbsp;Muhammed Yasul","doi":"10.4274/tpd.galenos.2022.60783","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2022.60783","url":null,"abstract":"<p><strong>Objective: </strong>Parasitizing in the small intestines of cattle, buffalo and bison, <i>Toxocara vitulorum</i> is seen in countries with humid tropical and subtropical climates, including Türkiye. Adult parasites can cause digestive disorders such as loss of appetite, weakness, diarrhea or constipation, and sometimes death, especially in calves. This study was planned to investigate the distribution of <i>T. vitulorum</i> in cattle of the Ağrı region.</p><p><strong>Methods: </strong>In this study, stool samples of the size of a walnut were taken from the rectum of 200 calves 0-6 months old and 200 cattle older than 1 year in the province of Ağrı and its districts, and the preparations were prepared using the saturated zinc sulfate flotation method and the preparations were examined under a light microscope.</p><p><strong>Results: </strong><i>T. vitulorum</i> eggs were detected in 70 (35%) of 200 calves aged 0-6 months and 21 (10.5%) of 200 cattle over one year old. The difference in positivity between cattle over one year old and calves was statistically significant (p=0.001). With fecal examination ın 22 of the calves (11%), <i>Trichostrongylidae</i> spp. eggs were detected.</p><p><strong>Conclusion: </strong>It was determined that the prevalence of <i>T. vitulorum</i> in calves was high in Diyadin, Eleşkirt, Doğubayazıt, Hamur, Taşlıçay, Tutak and Patnos districts of Ağrı province. We believe that larger-scale studies should be conducted on the spread of this parasite, which causes significant low yields in cattle breeding.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"47 2","pages":"88-92"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Parasitic Contamination in Vegetables Collected from Local Markets in İzmir Province, Türkiye","authors":"Fatma Bilgiç,&nbsp;Eylem Akdur Öztürk,&nbsp;Sefer Özer Babat,&nbsp;Aylin Babaoğlu,&nbsp;Derya Dirim Erdoğan,&nbsp;Metin Korkmaz","doi":"10.4274/tpd.galenos.2023.51422","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2023.51422","url":null,"abstract":"<p><strong>Objective: </strong>Fresh vegetables are an important part of a healthy and nutrient-rich diet but the consumption of raw vegetables without proper washing is the main way for transmission of parasites. This study was aimed at determining the rate of parasitic contamination in prewashed fresh vegetables sold at randomly selected 10 retail markets which is the last step to reach the consumer in İzmir, Türkiye.</p><p><strong>Methods: </strong>A total of 80 samples selected from eight types of vegetables including tomato, spinach, lettuce, rocket, mint, parsley, dill, and cucumber were examined for parasitic agents microscopically by sedimentation method after washing samples with normal saline. Statistical analysis was performed using SPSS software version 20.0.</p><p><strong>Results: </strong>Protozoan cysts, helminth eggs, and larvae were detected in 21 (26.2%) of 80 samples from eight different vegetable species. Rhabditidiform larvae 18.7%, <i>Blastocystis</i> spp. 5%, <i>Toxocara</i> spp. 2.5%; <i>Ascaris</i> spp., <i>Fasciola</i> spp., <i>Entamoeba histolytica/ Entamoeba dispar</i> and hooked worms were found in 1.2%. Spinach and mint samples were contaminated with parasites significantly more than other fresh vegetable samples (p<0.008, odds ratio =80.0; p<0.017, odds ratio =46.6 respectively). <i>Cruznema</i> spp., a plant nematode, was found at the highest rate according to the results of culture, polymerase chain reaction and sequencing, respectively.</p><p><strong>Conclusion: </strong>In this study, the parasitic contamination was found in approximately one of the four vegetables sold in randomly selected markets in İzmir. These findings show that vegetables sold in local markets can cause parasitic infections if they are consumed without adequate washing and awareness should be raised on this issue. In addition, it was concluded that morphological examinations should be confirmed by molecular studies and sequencing as much as possible in order to avoid misdiagnosis of rhabditidiform larvae.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"47 2","pages":"105-111"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9556325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of <i>Aelurostrongylus abstrusus</i> Prevalence and Risk Factors in Cats from Balıkesir","authors":"İlayda Yıldırım,&nbsp;Buse Öztürk,&nbsp;Damla Ekin Solmaz,&nbsp;Ersoy Baydar,&nbsp;Uğur Aydoğdu","doi":"10.4274/tpd.galenos.2022.87609","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2022.87609","url":null,"abstract":"<p><strong>Objective: </strong>The lungworms are nematodes that live as parasites in cat lungs. It is reported that the most common lungworm is <i>Aelurostrongylus abstrusus</i> in cats, and also <i>Capillaria aerophila</i> is observed. The lungworms can cause infection of the lower respiratory tract, often resulting in bronchitis and pneumonia. In this study, it was aimed to determine the prevalence and risk factors of <i>A. abstrusus</i> in cats in the Balıkesir province.</p><p><strong>Methods: </strong>This study was carried out on 100 cats in Balıkesir province. Fresh stool samples (>15 g) were collected for detection of lungworms after recorded all cat information (breed, age, sex, etc.). Parasite-specific L1 forms were determined from the stool samples by the Baerman-Wetzel technique.</p><p><strong>Results: </strong><i>A. abstrusus</i> L1's were found in 5 of the 100 stool samples examined. While symptoms of respiratory system disease were observed in 2 of the cats with lungworm, no clinical finding of the presence of parasites was found in 3 of them.</p><p><strong>Conclusion: </strong><i>A. abstrusus</i> was observed at a level of 5% in this first prevalence study in cats in Balıkesir province.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"47 2","pages":"78-82"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9556331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Nasopharyngeal Myiasis Caused by <i>Sarcophaga</i> sp","authors":"Mutalip Çiçek,&nbsp;Fatih Çakır,&nbsp;Duygu Neval Sayın İpek,&nbsp;Alican Bilden,&nbsp;Eşref Akıl","doi":"10.4274/tpd.galenos.2023.86547","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2023.86547","url":null,"abstract":"<p><p>Myiasis is a parasitic infestation of tissues and body cavities of vertebrates by <i>Diptera larvae</i>. Nasal myiasis is mostly caused by the <i>Sarcophagidae</i> and <i>Calliphoridae</i> families. Many predisposing factors play a role in the appearance of nasal myiasis. In the treatment of the disease, the use of antiseptics together with mechanical cleaning is recommended. In this report, a case of nasopharyngeal myiasis in a 75-year-old patient hospitalized in the intensive care unit is presented. Nine larvae were detected in the patient's nose. Larvae were removed from the area and were cleaned with iodine solution for three days. As a result of macroscopic and microscopic examination, the larvae were identified as the third stage of <i>Sarcophaga</i> sp. in order to prevent myiasis infestations, personnel working in places where the patient is unconscious, such as intensive care units, should daily check the patient's body cavities such as nose, mouth and ear cavities, and perform their care and cleaning.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"47 2","pages":"124-126"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution of Aedes (<i>Stegomyia</i>) cretinus in Türkiye","authors":"Fatih Mehmet Şimşek,&nbsp;Sare İlknur Yavaşoğlu","doi":"10.4274/tpd.galenos.2023.72692","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2023.72692","url":null,"abstract":"<p><strong>Objective: </strong><i>Aedes cretinus</i>, a white and black stripped <i>Aedes species</i>, shares morphological similarities with <i>Aedes albopictus</i> and <i>Aedes aegypti</i> which are among the most important vectors and invasive species in the world. Due to its limited distribution and low population density, information on the biology and ecology of the species has been limited so far. This study aimed to determine distribution of Ae. <i>cretinus</i> in Türkiye.</p><p><strong>Methods: </strong>Field works have been carried out in the Mediterranean, Aegean and Marmara Regions of Türkiye. Larval samples were collected by larval dippers while adult mosquito catches were performed using the human landing catch method and CDC-light traps.</p><p><strong>Results: </strong>A total of 44 different Ae. <i>cretinus</i> populations were identified in the Mediterranean, Aegean and Marmara Regions of Türkiye. The larval specimen collected from small containers, tires, tree holes and natural small habitats. A plane (<i>Platanus orientalis</i>), walnut (<i>Juglans regia</i>), Türkiye oak (<i>Quercus cerris</i>), chestnut (<i>Castenea sativa</i>) and cedar (<i>Cedrus libani</i>) tree holes are the main larval habitats in which the specimen collected. In some localities, larvae were found together with <i>Anopheles plumbeus</i>, <i>Anopheles claviger</i> and <i>Aedes geniculatus</i> larvae in tree holes. Human landing catch method captured a greater number of females than CDC-light traps.</p><p><strong>Conclusion: </strong>This study determined the distribution of Ae. <i>cretinus</i> in Türkiye for the first time. Information on respective geographic distribution of Ae. <i>cretinus</i> is fundamental for effective control programmes. Further studies are needed to understand the biology and ecology of these species.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"47 2","pages":"117-123"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Analysis of Serology and Radiology Results in Patients with Suspected Cystic Echinococcosis Through 3 Years Period","authors":"Büşra Betül Özmen Çapın,&nbsp;Barış Can,&nbsp;Meltem Kurşun,&nbsp;Canan Cimşit,&nbsp;Ayşegül Karahasan","doi":"10.4274/tpd.galenos.2023.24186","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2023.24186","url":null,"abstract":"<p><strong>Objective: </strong>Cystic echinococcosis (CE), caused by the larval stage of <i>Echinococcus granulosus</i> sensu latu, is one of the neglected zoonotic infectious diseases and Türkiye is among the endemic countries. This study was designed to analyze serology results for patients who were diagnosed as CE by clinical symptoms and radiological methods over a three-year period.</p><p><strong>Methods: </strong>Sera were analyzed for Anti-<i>E. granulosus</i> IgG by a chemiluminescence immunoassay (CLIA) (HYDATIDOSIS VIRCLIA^® IgG MONOTEST, Vircell) using the VIRCLIA^® (CLIA; Vircell, Granada, Spain) and results processed by the dedicated software. Cut-off for a positive test was ≥1.1 index value. Echinococcal cysts were detected based on ultrasonography, computed tomography, and magnetic resonance imaging.</p><p><strong>Results: </strong>A total of 244 sera were analyzed from 109 patients, during three-year-period from January 2018 to December 2020. Anti-<i>E. granulosus</i> IgG was ordered twice in 89 patients, three times in 15 patients, four times in four patients, and five times in one patient. CLIA test was positive among 41 of 109 (37.6%) patients in whom 32 (76%) had only hepatic involvement, whereas in 5 (12%) hepatic and pulmonary involvement were coexisted. The mean age of seropositive patients was 39.8 (6-75±2.72) and 61.9% of them (n=26) were female. Time intervals between sequential test orders varied from 1 day to 33 months. Eight seropositive patients turned out to be negative, and one of 66 seronegative patients became seropositive. Positive test results were converted to negative in the case of therapy or cyst inactivity.</p><p><strong>Conclusion: </strong>We may conclude that CLIA could be used as a complementary tool for CE patient follow-up.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"47 2","pages":"83-87"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9556330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Analysis of Serology and Radiology Results in Patients with Suspected Cystic Echinococcosis Through 3 Years Period.","authors":"Büşra Betül Özmen Çapın, Barış Can, Meltem Kurşun, C. Cimşit, A. Karahasan","doi":"10.4274/tpd.galenos.2022.24186","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2022.24186","url":null,"abstract":"OBJECTIVE\u0000Cystic echinococcosis (CE), caused by the larval stage of Echinococcus granulosus sensu latu, is one of the neglected zoonotic infectious diseases and Türkiye is among the endemic countries. This study was designed to analyze serology results for patients who were diagnosed as CE by clinical symptoms and radiological methods over a three-year period.\u0000\u0000\u0000METHODS\u0000Sera were analyzed for Anti-E. granulosus IgG by a chemiluminescence immunoassay (CLIA) (HYDATIDOSIS VIRCLIA® IgG MONOTEST, Vircell) using the VIRCLIA® (CLIA; Vircell, Granada, Spain) and results processed by the dedicated software. Cut-off for a positive test was ≥1.1 index value. Echinococcal cysts were detected based on ultrasonography, computed tomography, and magnetic resonance imaging.\u0000\u0000\u0000RESULTS\u0000A total of 244 sera were analyzed from 109 patients, during three-year-period from January 2018 to December 2020. Anti-E. granulosus IgG was ordered twice in 89 patients, three times in 15 patients, four times in four patients, and five times in one patient. CLIA test was positive among 41 of 109 (37.6%) patients in whom 32 (76%) had only hepatic involvement, whereas in 5 (12%) hepatic and pulmonary involvement were coexisted. The mean age of seropositive patients was 39.8 (6-75±2.72) and 61.9% of them (n=26) were female. Time intervals between sequential test orders varied from 1 day to 33 months. Eight seropositive patients turned out to be negative, and one of 66 seronegative patients became seropositive. Positive test results were converted to negative in the case of therapy or cyst inactivity.\u0000\u0000\u0000CONCLUSION\u0000We may conclude that CLIA could be used as a complementary tool for CE patient follow-up.","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"1 1","pages":"83-87"},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88647351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}