Archivos de Neurociencias最新文献

{"title":"Consideraciones éticas en el uso de animales de experimentación","authors":"Iván Pérez-Neri","doi":"10.31157/an.vi.342","DOIUrl":"https://doi.org/10.31157/an.vi.342","url":null,"abstract":"","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82170148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estudio del uso de marcos de referencia en el trastorno del espectro autista: una revisión sistemática","authors":"Katy Arlette Pérez-Estrada, Eliane Ronzón González, J. Fernández-Ruíz","doi":"10.31157/an.v27i3.337","DOIUrl":"https://doi.org/10.31157/an.v27i3.337","url":null,"abstract":"Los marcos de referencia permiten ubicar dentro del espacio objetos y personas, y tienen impacto en el mundo espacial y social. El marco de referencias egocéntrico (MRE) permite al sujeto posicionarse desde su propia perspectiva, mientras que el marco de referencia alocéntrico (MRA) permiten establecer relaciones entre los objetos sin tomar en cuenta la propia perspectiva. Algunas de las investigaciones realizadas sobre el trastorno del espectro autista (TEA) han encontrado alteraciones en los marcos de referencia. El objetivo de este trabajo fue evaluar mediante el análisis de artículos originales si las personas con TEA presentan alteraciones en el MRE, MRA o en ambos. Se utilizó la metodología PRISMA. La búsqueda de datos se realizó en PubMed, ScienceDirec y Springer link, utilizando la siguiente combinación de palabras: egocentrism, allocentric, spatial, cognition, visuospatial perspective taking y ASD. Se encontraron 964 artículos de los cuales 15 cumplieron los criterios establecidos. De los estudios que realizaron tareas para evaluar el MRE, tres reportaron alteraciones y siete un funcionamiento normal. En cambio, de los que estudiaron el MRA, ocho mostraron alteraciones y seis un funcionamiento normal. La evidencia apunta a que los TEA presentan alteraciones en el MRA, pero no en el MRE, sin embargo, esto no es concluyente, ya que las investigaciones presentan sesgo, las tareas y las edades de los sujetos son heterogéneas, las muestras son pequeñas y los diseños y procedimientos variados. En conclusión, la evidencia aún no es decisiva sobre el deterioro del uso de los marcos de referencia en TEA.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"106 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87909287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pterional Approach: Technical Variations, Functional, and Cosmetic Outcome in a Series of 1000 Patients","authors":"S. Luzzi, Alice Giotta Lucifero, Matías Baldoncini, Á. Campero, S. Elbabaa, R. Galzio","doi":"10.31157/an.v1iinpress.335","DOIUrl":"https://doi.org/10.31157/an.v1iinpress.335","url":null,"abstract":"INTRODUCTION \u0000Most of the versatility of the pterional approach depends on a series of variations progressively reported by several groups, but little emphasized over the years. \u0000The present study condenses the technical notes which the authors adopted in their practice to maximize the surgical freedom of the pterional approach, at once lessening the approach-related complication rate. \u0000METHODS \u0000Data of a series of patients who underwent a pterional approach between January 2011 and May 2021 were retrospectively reviewed focusing on the technical variations compared to the original Yaşargil’s description. The anatomical rationale, technique, and advantages were outlined and validated through the appraisal of functional and cosmetic complications.    \u0000RESULTS \u0000994 patients were reviewed. Head extension was avoided in the case of anterior clinoidectomy. A single double-layered galea-pericranium flap was used for duraplasty. The submuscular technique, with compulsive preservation of deep temporal fascia and deep temporal arteries, was preferred for temporalis muscle dissection. McCarty keyhole was never used, thus avoiding exposing the orbit if unnecessary. Widening of the superior orbital fissure and thinning of the orbital roof allowed to significantly increase the working area. The average follow-up was 7.2 years. The overall rate of functional and cosmetic complications was 2.1. \u0000DISCUSSION \u0000In the authors' experience, the gradual adoption of technical variations related to the patient's positioning, soft tissue dissection, bony work, dura opening, and reconstruction allowed to enhance the versatility of the pterional approach concurrently decreasing the risk of functional and cosmetic complications.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77377241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of manganese in the pathophysiology of hepatic encephalopathy: scoping review protocol","authors":"I. Pérez-Neri, H. Sandoval, Antonio Malvaso, N. Indika, C. Alarcon-Ruiz, M. Ebrahimian, C. Ríos","doi":"10.31157/an.v1iinpress.354","DOIUrl":"https://doi.org/10.31157/an.v1iinpress.354","url":null,"abstract":"Introduction: Hepatic encephalopathy (HE) is a neuropsychiatric complication of liver disease and/or portosystemic blood shunting, characterized by alterations of alertness, personality, cognition, and motor functions. Its severity is defined from mild symptoms to coma according to four grades. This disease may affect several brain regions including the cingulate gyrus, the insular cortex, and the globus pallidus. The pathophysiology of HE is thought to be multifactorial and involves manganese accumulation in the brain, damaging effect of ammonia on glial cells, etc. Previous studies describe the pathophysiology of HE or the effect of manganese in the central nervous system but there is no review addressing both topics from an integrative perspective and using a systematic methodology. This scoping review aims to evaluate the role of manganese in HE. Methods: Published studies (all publication types) will be retrieved from Web of Science, MEDLINE, Scopus, EBSCOhost, Ovid, and Google Scholar. Inclusion criteria are: studies reporting manganese levels in any biological sample or tissue of patients with HE, any experimental model reporting the effect of manganese administration on measures of neuroprotection in models of liver damage, or showing an effect on manganese levels in the liver and/or the brain. Exclusion criteria are: studies reporting subjects exposed occupationally or environmentally to manganese, or written in languages different than Spanish or English that could not be appropriately translated, or whose full-text files could not be retrieved. Either clinical or preclinical studies will be analyzed separately but might be discussed together. Data summaries will be presented in graphs, figures, and tables. A narrative synthesis will be presented. This protocol complies with PRISMA-P.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"130 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74599925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efectos del entrenamiento de fuerza en personas con esclerosis múltiple","authors":"Alejandra Alonso Calvete, Tecla María Cadilla-Acevedo, Y. González-González, I. Da Cuña-Carrera","doi":"10.31157/an.vi.315","DOIUrl":"https://doi.org/10.31157/an.vi.315","url":null,"abstract":"Introducción: La esclerosis múltiple (EM) es la enfermedad degenerativa más común en adultos jóvenes y su tratamiento rehabilitador se centra en mejorar los síntomas y restablecer la funcionalidad. Uno de los métodos estudiados recientemente es el trabajo de la fuerza muscular, simultáneo con ejercicios de equilibrio, mejora de la marcha y habilidad corporal. Por ello, el objetivo de esta revisión es analizar la aplicación de los programas de entrenamiento de la fuerza en sujetos con EM. \u0000Métodos:  En febrero de 2020 se consultaron las bases de datos Cinahl y Medline, utilizando los descriptores MeSH “multiple sclerosis” y “resistance training”. La búsqueda arrojó 89 resultados, de los que se analizaron 17 estudios que se adaptaban al objetivo de revisión. \u0000Resultados: Se han analizado los efectos de programas de entrenamiento aislado de la fuerza mediante protocolos de alta intensidad aeróbicos continuos o interválicos, con incrementos de la carga de trabajo o resistencia progresiva, entrenamientos de suspensión (TRX), resistencias con el peso corporal, hatha yoga, y su combinación con ejercicio cardiovascular, actividad física autoguiada, electroestimulación neuromuscular o entrenamientos funcionales de funcionalidad y marcha. Se analizaron las variables de Fuerza y función neuromuscular (espasticidad, propiocepción), funcionalidad (movilidad, capacidad motora, equilibrio, fatiga y fatigabilidad), parámetros metabólicos (tolerancia a la glucosa, factor neurotrófico del cerebro (BDNF), esfingosina-1-fosfato (S1P), composición corporal, Cortisol y DHEA, mediadores inflamatorios, marcadores inmunomoduladores, capacidad aeróbica) y parámetros como la calidad de vida, satisfacción, adherencia y participación. \u0000Conclusiones: Los protocolos de entrenamiento de la fuerza de uso aislado o combinado con otros métodos mejora la fuerza muscular y, funcionalidad de la marcha de los sujetos con EM, así como de parámetros metabólicos. Sin embargo, no queda demostrada su implicación en la regulación de factores neuroprotectores. \u0000 ","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"159 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77208097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La leptina y su papel en la neuroendocrinología de la obesidad","authors":"C. Diéguez-Campa, Jorge Castillo Ledón-Pretellini, Jesús Alejandro De los Santos-Coyotl, Luis I. Angel-Chávez, Iliana Arely Flores-Apodaca, Iván Pérez Neri","doi":"10.31157/an.v1iinpress.323","DOIUrl":"https://doi.org/10.31157/an.v1iinpress.323","url":null,"abstract":"La leptina es una hormona que participa en múltiples funciones biológicas. Esto es debido a la señalización que ejerce a nivel hipotalámico produciendo un estímulo de saciedad, balance en el gasto de energía, y un adecuado control del peso corporal. En los últimos años, se ha reportado un aumento en la mortalidad asociada con obesidad en población mexicana, posicionando a esta enfermedad como una de las principales causas, debido al desarrollo de comorbilidades asociadas a su patología. Se ha estudiado la participación de la leptina como una hormona pleiotrópica con propiedades cruciales para el desarrollo de sobrepeso y obesidad. Se ha observado que las alteraciones en su receptor predisponen a una resistencia a la leptina condicionando una respuesta pobre en la estimulación de la saciedad y, a su vez, un aumento en el consumo de alimentos. Otros estudios sugieren que las dietas con un alto contenido calórico producen una hiperactivación en la corteza cerebral asociada al sentido del gusto, generando un estímulo de recompensa que induce a un mayor consumo de alimentos, llevando paulatinamente a un incremento del tejido adiposo en el organismo. Investigaciones realizadas mediante la aplicación de leptina exógena en ratones han registrado una disminución transitoria del peso corporal con una disminución en el consumo de alimentos. Por estas razones, es importante describir y analizar la participación de la leptina en las señalizaciones neuroendocrinas de la obesidad, obteniendo una mayor comprensión y entendimiento de la enfermedad. El presente manuscrito pretende describir este tema con fines educativos.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89633944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective effects of Buxus hyrcana against memory impairment and oxidative stress in a pentylenetetrazole-kindled epileptic rat model","authors":"V. Azizi, F. Allahyari, A. Hosseini","doi":"10.31157/an.vi.319","DOIUrl":"https://doi.org/10.31157/an.vi.319","url":null,"abstract":"Pentylenetetrazole (PTZ) is a chemical substance which is largely used for the induction of seizure and epilepsy in the animal model, and it can also, disrupts free radicals balance and cause oxidative stress in the body with a negative impact on memory and learning. In this study, the medicinal plant Buxus hyrcana, was used to evaluate its effect on oxidative stress and memory deficit caused by PTZ in the rats. Twenty-four rats were randomly allocated to 4 groups: control negative under treatment with PTZ (sub-threshold dose 35 mg/kg for one month), control positive under treatment with phenobarbital (PB-30 mg/kg), and two PTZ groups under treatment with B. hyrcana extract (BHE-300, and -600 mg/kg). Standard passive avoidance test was used to evaluate retention and recall (evaluation of memory and learning). After behavioral evaluation, rats were anesthetized, brains were removed, and following preparation of brain homogenates, oxidative stress was evaluated using specified methods. Step-through latency in passive avoidance test in the BHE receiving group was greater than PTZ group (p<0.001). In addition, brain lipid peroxidation malondialdehyde (MDA) and nitric oxide (NO) level in BHE-treated group was significantly lower (p<0.001) and the reduced glutathione (GSH) activity levels were significantly greater versus PTZ group (p<0.001). Our results showed that BHE could prevent memory deficit and ameliorate oxidative stress in the PTZ-kindled rats.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90464516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic potential of dehydroepiandrosterone for Parkinson's disease: scoping review protocol","authors":"I. Pérez-Neri, C. Diéguez-Campa, H. Sandoval, Vivian-Aleisha Chávez, E. Castro-Martínez, C. Ríos","doi":"10.31157/an.vi.331","DOIUrl":"https://doi.org/10.31157/an.vi.331","url":null,"abstract":"Background: Parkinson's disease (PD) is a neurodegenerative disorder characterized by a progressive loss of nigrostriatal dopaminergic neurons. Its treatment is symptomatic and shows limited efficacy. Dehydroepiandrosterone (DHEA) is a hormone produced in the brain. Several studies have reported beneficial effects of the steroid in experimental models of PD and various human diseases, but its potential for PD is inconclusive. Therefore, it is necessary to evaluate current evidence to determine the therapeutic potential of DHEA administration for PD since it could be an effective and low-cost treatment. \u0000Objectives: We aim to evaluate the therapeutic potential of dehydroepiandrosterone administration in patients with PD. \u0000Inclusion criteria: Studies describing patients with PD receiving DHEA, and reporting an outcome --on disease course, severity, or adverse effects-- compared to either placebo, an inactive treatment or standard treatment. PD experimental models reporting an effect of DHEA treatment on measures of neuroprotection (cell death, motor activity, oxidative stress). \u0000Exclusion criteria: Studies written in languages different than Spanish or English that could not be appropriately translated, or whose full-text files could not be retrieved. \u0000Information sources: Web of Science, PubMed, Scopus, EBSCOhost, Cochrane Library, Google Scholar, and author's collections. \u0000Data charting: Data will be extracted by one researcher and verified by another using a pilot-tested predefined format. Non-systematic review articles (narrative, scoping or similar) will only be considered for narrative synthesis. \u0000This protocol complies with PRISMA 2020 statement and its main related extensions (PRISMA-A, PRISMA-P, PRISMA-Scr). It also complies with the Joanna Briggs Institute’s Manual for Evidence Synthesis.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87417675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efecto de la Asfixia perinatal e Hipotermia corporal en los potenciales evocados auditivos y el desarrollo en los primeros dos años de vida","authors":"Karla Maria Soler Limon, Gabriela del Pilar Romero Esquiliano, Pedro Valentín Romero Gutiérrez, Alberto Orozco Gutiérrez, Claudia Laura Calderon Jimenéz, Iván Rolando Rivera González","doi":"10.31157/an.vi.311","DOIUrl":"https://doi.org/10.31157/an.vi.311","url":null,"abstract":"La asfixia perinatal se asocia con alto riesgo de muerte así como riesgo de deterioro del neurodesarrollo tanto temprano como tardío, además los episodios graves pueden tener un efecto importante sobre la función auditiva, daño coclear y lesiones neuronales retrococleares. Con el uso como neuroprotector de la terapia de hipotermia corporal en las primeras 72hrs, se ha logrado mejorar la supervivencia de los neonatos, asi como los resultados en le neurodesarrollo en casos con EHI moderada a grave. Objetivo Describir las características de los PEATC de lactantes con EHI moderada y severa tratados con hipotermia corporal y su relación con el desarrollo alcanzado al año y dos años de edad. Material y Método se estudiaron 51 niños a los cuales se les realizaron PEATC a los 3, 6 y/o 12 meses de edad y se les evaluó el desarrollo a los 12 y 24 meses de edad con las pruebas Gesell, Bayley II y Bayley III. Resultados Los valores de PEATC fueron similares a los observados en niños sanos y se correlacionaron significativamente con el desarrollo en ambas edades, en especial las ondas I y III. Las categorías Normal/Alterado en los PEATC mostraron diferencias de una desviación estándar en la puntuación del desarrollo. Conclusiones los PEATC mostraron relación con el desarrollo posterior; la caracterización de normalidad/alteración que proponemos permitió mostrar a los PEATC como indicador de riesgo para el desarrollo, aun antes del daño franco en la vía auditiva.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83848427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tolosa-Hunt syndrome associated with coronavac / Sinovac vaccination against Covid-19","authors":"Rodolfo Pedro Molina-Martínez, Daniel Alejandro Vega-Moreno, José Darío Ochoa-Mena, María del Rosario López-Zapata, U. García-González","doi":"10.31157/an.vi.329","DOIUrl":"https://doi.org/10.31157/an.vi.329","url":null,"abstract":"Tolosa-Hunt syndrome consist of. unilateral or periorbital headache, paresis of the III, IV, and/or VI cranial nerve ipsilateral to the headache, and image evidence of pathology in the cavernous sinus or superior orbital fissure. We present the case of a 76 YO woman who developed Tolosa-Hunt syndrome posteriorly to the application of Sinovac vaccine against Covid-19.","PeriodicalId":34902,"journal":{"name":"Archivos de Neurociencias","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89222961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}