2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content最新文献_第5页

The improvement of the RS3 system for drug substructure searching RS3药物子结构搜索系统的改进

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657973

H. Lee, Hyunsang Kang, Yoonsook Lee, Byungchol Chang, Jaehyuk Cha

{"title":"The improvement of the RS3 system for drug substructure searching","authors":"H. Lee, Hyunsang Kang, Yoonsook Lee, Byungchol Chang, Jaehyuk Cha","doi":"10.1109/ICNIDC.2010.5657973","DOIUrl":"https://doi.org/10.1109/ICNIDC.2010.5657973","url":null,"abstract":"For the development of a new drug, medicinal chemists perform the structure-based drug design, i.e., search the existing drugs with the chemical structure similar to the chemical structure of the target drug. In brief, researcher and developer want to know drugs to have a specific chemical structure. Therefore, from large drug databases, it is necessary to give the information of selected drugs fast, which should have the members of a set of chemical moieties matching a user-defined query moiety. Substructure searching is the process of identifying the members of a set of chemical moieties that match a specific query moiety. Testing for substructure searching was developed in the late 1950s. In graph theoretical terms, this problem corresponds to determining which graphs in a set are subgraph isomorphic to a specified query graph. Testing for subgraph isomorphism has been proved, in the general case, to be an NP-complete problem. For the purpose of overcoming this difficulty, there were computational approaches. On the 1990s, a US patent has been granted on an atom-centered indexing scheme, used by the RS3 system; this has the virtue that the indexes generated can be searched by direct text comparison. This system is commercially usedihttp://www.acelrys.com/rs3). We define the RS3 system's drawback and present a new indexing scheme. This system treats substructure searching with substring matching by means of expressing chemical structure as predefined strings. However, it has insufficient ‘recall’ and ‘precision’ because of a fatal shortage of the indexing scheme. Expressing 2D chemical structure into ID a string has limit. Therefore, we break 2D chemical structure into ID structure fragments. We present in this paper a new index technique to improve recall and precision surprisingly.","PeriodicalId":348778,"journal":{"name":"2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134086270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research and implement of a novel Dynamic Load Sharing Algorithm for the multihomed terminals 一种新的多主终端动态负载共享算法的研究与实现

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657871

Haisheng Jiang, M. Xue, Fei Song

引用次数: 0

BibMiner: A service-oriented framework for bibliographic analysis service BibMiner:一个面向服务的书目分析服务框架

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657838

Bin Wu, Hongqiao Tian

{"title":"BibMiner: A service-oriented framework for bibliographic analysis service","authors":"Bin Wu, Hongqiao Tian","doi":"10.1109/ICNIDC.2010.5657838","DOIUrl":"https://doi.org/10.1109/ICNIDC.2010.5657838","url":null,"abstract":"The continued exponential growth in volume of literature data is giving birth to a new challenge to the bibliographic analysis service and the traditional features such as keyword search, author search and statistics services could not satisfy researchers for in-depth analysis. The emerging of community analysis in social networks is becoming a hot topic in many domains and disciplines such as sociology, computer science, and physics. Many methods have been proposed for revealing the structure of communities in networks. In this paper, we elaborate a prototype of our on-going constructed system, BibMiner, for digging hidden knowledge from the large-scale literature records. The major infrastructure of BibMiner makes a combination of Service-Oriented approaches and complex network theory, it is open and extensible to new features and services could be integrated more smoothly. To illustrate its functionality, we employ BibMiner to a real-world dataset and demonstrate an integrated analysis procedure on knowledge discovering. Most part of this paper is concentrated on system architecture which is detailed represented in Section 3.","PeriodicalId":348778,"journal":{"name":"2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content","volume":"344 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123185773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of XACML access control mechanism based on NETCONF subtree filtering rpc 基于NETCONF子树过滤rpc的XACML访问控制机制改进

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657947

Jinjin Wang, Bin Zhang, Guohui Li, Yan Li, Xuesong Gao

引用次数: 1

Inline dispersion compensation effect for 100GB/S PDM-CO-OFDM long-haul transmission systems 100GB/S PDM-CO-OFDM长途传输系统的在线色散补偿效果

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657925

Xuejun Liu, Yaojun Qiao, Yuefeng Ji

引用次数: 5

An effective relevance feedback algorithm for image retrieval 一种有效的图像检索相关反馈算法

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657782

Heng Chen, Zhicheng Zhao, A. Cai, Xiaohui Xie

引用次数: 12

A practical deployment of Intelligent Building Wireless Sensor Network for environmental monitoring and air-conditioning control 智能楼宇无线传感器网络环境监测与空调控制的实际部署

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657858

T. Zheng, Yajuan Qin, D. Gao, Junqi Duan, Hongke Zhang

引用次数: 18

Application of Linkclus in blogosphere Linkclus在博客圈中的应用

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657906

Seok-Ho Yoon, S. Song, Sang-Wook Kim, Jiwoon Ha, Junghoon Lee, Hanil Kim

引用次数: 0

Analysis of packets delivery probability on intersections for VANETs in city scenarios 城市场景下vanet交叉口数据包投递概率分析

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657813

Yuanzhen Li, J. Liao, Tonghong Li, Xiaomin Zhu, Lei Zhang, Shengxian Xie

引用次数: 2

Optimum number of secondary users in cooperative spectrum sensing using adaptive threshold 基于自适应阈值的协同频谱感知中辅助用户的最优数量

2010 2nd IEEE InternationalConference on Network Infrastructure and Digital Content Pub Date : 2010-12-03 DOI: 10.1109/ICNIDC.2010.5657895

Hanbyeul Na, Sunwoo Kim

引用次数: 5