{"title":"High-speed image data acquisition of OCT utilizing push-pull operation of fiber-optic piezoelectric modulators","authors":"M. Ohmi, K. Nohara, M. Haruna","doi":"10.1109/APBP.2004.1412254","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412254","url":null,"abstract":"A fiber-optic piezoelectric modulator (PZM) is a promising tool for high-speed image data acquisition of OCT. We demonstrate here the high-speed OCT utilizing push-pull operation of PZMs which can provide up to 2000 scan/sec with a scan depth of 2.5 mm. The axial resolution is 17 /spl mu/m for the 1.3-/spl mu/m wavelength. A motion-artifact-free in-vivo OCT of human finger tip is presented.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124372414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Gao, Huijuan Zhao, Y. Tanikawa, K. Homma, Y. Yamada
{"title":"A comparative investigation of influences of target size and contrast on diffuse optical tomography by featured-data and full time-resolved reconstructions","authors":"F. Gao, Huijuan Zhao, Y. Tanikawa, K. Homma, Y. Yamada","doi":"10.1109/APBP.2004.1412322","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412322","url":null,"abstract":"This paper presents time-resolved diffuse optical tomographic imaging of human lower legs and forearms. To identify the sources that cause the low quantitativeness in the reconstructed images, a comparative study is carried out on reality-simulating numerical phantoms using both the featured-data and full time-resolved algorithms.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"356 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115025419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasonic speckle denoising using the combination of wavelet transform and Wiener filter","authors":"S. Udomhunsakul, P. Wongsita","doi":"10.1109/APBP.2004.1412348","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412348","url":null,"abstract":"Ultrasonic images are inherently affected by multiplicative noise, which is due to the coherent wave interference in tissue. This paper presents a method for ultrasonic speckle denoising using the combination of wavelet transform and wiener filter to effectively reduce the speckle noise while preserving the resolvable details. In our method, the steps involved are finding the 2D discrete wavelet transform of the logarithmic image. Then, the wiener filter is used to apply over areas in each detail subband (HH,HL and LH). Next the inverse wavelet transform is computed and applying the inverse logarithm. To evaluate the denoising performance, mean square error (MSE), signal to mean square error (S/mse) and edge preservation (/spl beta/) are used. From the experimental results, we found that our approach leads to an effective method for ultrasonic speckle denoising.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129823065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Depth-adaptive voxel size reconstruction for diffuse reflective optical tomography","authors":"R. Endoh, M. Fujii, K. Nakayama","doi":"10.1109/APBP.2004.1412311","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412311","url":null,"abstract":"We study diffuse reflective optical tomography (DROT), aiming at the real-time imaging of the redox state change of the human cerebral cortex with the brain activity. In the uniform voxel size and simple regularization scheme we studied so far, the spatial resolution in the shallow region is unnecessarily good, whereas the noise and the sensitivity in the shallow region are too large to recover the signal in the depth. In this report, we present the result of the depth-adaptive voxel size reconstruction. By assigning wider lateral voxel size in the shallow range, the noise and the sensitivity in the shallow range is suppressed so that the signal in the deep range would be less masked by the presence of the unwanted target in the shallow range. We demonstrate the improvement of the 3-dimensional reconstructed image using the proposed depth-adaptive voxel size reconstruction.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131365877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Dong, Wen Lo, Yen Sun, S. Teng, Yuan Liu, Hsuan-Shu Lee, Hsiao-Ching Chen, L. Chiou, Guan-Tarn Huang, Sung-Jan Lin, S. Jee, H. Tan, Wei-Chou Lin
{"title":"Multiphoton optical biopsy","authors":"C. Dong, Wen Lo, Yen Sun, S. Teng, Yuan Liu, Hsuan-Shu Lee, Hsiao-Ching Chen, L. Chiou, Guan-Tarn Huang, Sung-Jan Lin, S. Jee, H. Tan, Wei-Chou Lin","doi":"10.1109/APBP.2004.1412296","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412296","url":null,"abstract":"Multiphoton microscopy is to a powerful imaging modality in the life sciences. The improved image contrast, greater imaging depths, and focus limited photodamage enable multiphoton microscopy to be especially useful for in vivo bioimaging applications. For multiphoton microscopy to be widely applicable in for in vivo biopsy applications, characterization of the tissues of interest must first be performed ex vivo. This presentation is an overview of the microscopic and spectroscopic characterization of the tissue types being pursued by my group. Both multiphoton images and spectroscopic information of a diverse range of normal, damaged, or diseased tissues will be presented and the implications of our results discussed.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115166140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jihoon Na, Jooeun Im, Jinchae Kim, EunSeo Choi, Jae Ho Baek, B. Lee
{"title":"Axial resolution enhancement for an OCT system implemented by mechanically induced long-period fiber grating","authors":"Jihoon Na, Jooeun Im, Jinchae Kim, EunSeo Choi, Jae Ho Baek, B. Lee","doi":"10.1109/APBP.2004.1412317","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412317","url":null,"abstract":"We demonstrate a spectral filtering method that can enhance the axial resolution of an OCT system. A mechanically induced long-period grating was used to tailor the spectral shape of an in-house made Er-doped fiber amplified spontaneous emission source. The proposed method improved the visibility of the OCT image dramatically.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115232908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Uchibori, T. Kojima, H. Tsunashima, T. Shiozawa
{"title":"Near-infrared spectroscopic measurement of brain activity for syntactic processing","authors":"A. Uchibori, T. Kojima, H. Tsunashima, T. Shiozawa","doi":"10.1109/APBP.2004.1412272","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412272","url":null,"abstract":"We conducted a near-infrared spectroscopic experiment of brain activity for language processing. Syntactic aspects of language are particularly focused on in the stimuli. Increase in blood flow around Broca 's area is measured, as expected.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116198805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Mashita, M. Ueno, M. Ohmi, H. Arimoto, N. Kakuta, M. Haruna, Y. Yamada
{"title":"Measurement of the optical properties of nails","authors":"Y. Mashita, M. Ueno, M. Ohmi, H. Arimoto, N. Kakuta, M. Haruna, Y. Yamada","doi":"10.1109/APBP.2004.1412269","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412269","url":null,"abstract":"We have measured the scattering and the absorption coefficients of nails at wavelengths from 800 to 1900 nm by the combination of integrating sphere measurements and an inverse Monte Carlo method. Also the dependences of these coefficients on surface roughness and humidity were investigated.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122430628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yen Sun, Jiunn-Wen Su, Sung-Jan Lin, S. Jee, C. Dong
{"title":"An investigation of the relationship between the transdermal drug delivery and membranes fluidity by multiphoton imaging of Laurdan","authors":"Yen Sun, Jiunn-Wen Su, Sung-Jan Lin, S. Jee, C. Dong","doi":"10.1109/APBP.2004.1412340","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412340","url":null,"abstract":"Multiphoton microscopy is a three-dimensional imaging technique with a number of advantages. For example, multiphoton microscopy can image tissues up to a depth of a few hundred micrometers, at high resolution and with improved contrast. In this work, we used multiphoton microscopy in investigating the actions of the chemical enhancer oleic acid in transdermal drug delivery. Technique of generalized polarization (GP) imaging and polarization (P) imaging associate with Laurdan to monitor the lipid layer changes caused by the addition of oleic acid. Our study will help to develop more effective methodologies in the delivering of molecules across biological barriers.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114631090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ken-Ming Guo, Shu-Fang Cheng, L. Chau, Jaw-Luen Tang
{"title":"Optical biosensor based on colloidal gold-modified long-period fiber grating","authors":"Ken-Ming Guo, Shu-Fang Cheng, L. Chau, Jaw-Luen Tang","doi":"10.1109/APBP.2004.1412354","DOIUrl":"https://doi.org/10.1109/APBP.2004.1412354","url":null,"abstract":"A novel class of fiber-optic biosensor that exploits the localized surface plasmon resonance of self-assembled gold colloids on the grating portion of a long-period fiber grating is proposed. When the gold colloidal surface was modified with DNP, experimental results show that the signal increases linearly with increasing concentration of the analyte, and the detection limit of the sensor for antiDNP is 3.80/spl times/10/sup -7/ M.","PeriodicalId":346624,"journal":{"name":"The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130067738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}