M. Solano-Genesta , C. Lome-Maldonado , A. Orozco-Pelayo , G. Morgan-Villela , C. Zuloaga-Fernández del Valle , A.O. Cortés-Flores , L.A. García-González , R.C. Miranda-Ackerman , A.S. Carballo-Uribe , E. Morgan-Ochoa , C. Navarro-Fernández , F. Rubio-Macías , A. González-Ojeda
{"title":"Good syndrome associated with pure red cell aplasia in a patient with a history of thymoma: A case report and literature review","authors":"M. Solano-Genesta , C. Lome-Maldonado , A. Orozco-Pelayo , G. Morgan-Villela , C. Zuloaga-Fernández del Valle , A.O. Cortés-Flores , L.A. García-González , R.C. Miranda-Ackerman , A.S. Carballo-Uribe , E. Morgan-Ochoa , C. Navarro-Fernández , F. Rubio-Macías , A. González-Ojeda","doi":"10.1016/j.rmu.2017.11.001","DOIUrl":"10.1016/j.rmu.2017.11.001","url":null,"abstract":"<div><h3>Objectives</h3><p>Good syndrome is a rare condition in which a thymoma is associated with hypogammaglobulinemia. It is also characterized by low or absent B-cells, CD4+ T-cell lymphopenia, inverted CD4/CD8+ T-cell relation, and repeated bacterial, viral, and fungal infections, as well as with various autoimmune disorders.</p></div><div><h3>Case report</h3><p>We report the case of a 62-year-old female patient who after resection of a thymoma developed constipation and recurrent lower respiratory and urinary tract infections. She underwent left hemicolectomy as well as symptomatic and antibiotic treatment. Two years later the patient develops refractory anemia; a bone marrow biopsy shows hypo-cellularity and no red cell precursors with negative CD 71 staining. The diagnosis of pure red cell precursor aplasia (PRCA) is made. Recurrent bacterial infections of the respiratory and urinary tracts continue, and therefore treatment with G and A immunoglobulins starts. Finally, the absence of B lymphocytes and inversion of CD4/CD8 relation confirms the diagnosis of Good syndrome associated with PRCA.</p></div><div><h3>Discussion</h3><p>The discovery of Good Syndrome and PRCA after the resection of a thymoma, as seen in the current case, is very unusual. This case illustrates both the rareness presentation of Good syndrome with PRCA and the persistent infections seen in these patients. Early recognition of these entities results in lower mortality and morbidity.</p></div>","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"19 77","pages":"Pages 194-197"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmu.2017.11.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82142133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Á.R. Lugo-Mata, A. S. Urich-Landeta, A. L. Andrades-Pérez, M. J. León-Dugarte, L. A. Marcano-Acevedo, M. Guillén
{"title":"Factors associated with the level of knowledge about hypertension in primary care patients","authors":"Á.R. Lugo-Mata, A. S. Urich-Landeta, A. L. Andrades-Pérez, M. J. León-Dugarte, L. A. Marcano-Acevedo, M. Guillén","doi":"10.1016/J.RMU.2017.10.008","DOIUrl":"https://doi.org/10.1016/J.RMU.2017.10.008","url":null,"abstract":"","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"7 1","pages":"184-188"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86928982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Jack-in-the- (in-)box: Beware of predatory journals","authors":"C. D. L. Garza, M. Koschwitz","doi":"10.1016/J.RMU.2017.10.002","DOIUrl":"https://doi.org/10.1016/J.RMU.2017.10.002","url":null,"abstract":"","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"22 2 1","pages":"150-151"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83826126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.L. Iglesias-Benavides, V.M. Cedeño-Morales, G. Guerrero-González, A. Guzmán-López
{"title":"Labor trials in 300 patients with a previous cesarean section","authors":"J.L. Iglesias-Benavides, V.M. Cedeño-Morales, G. Guerrero-González, A. Guzmán-López","doi":"10.1016/j.rmu.2017.10.005","DOIUrl":"https://doi.org/10.1016/j.rmu.2017.10.005","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the safety and efficacy of labor in patients with a previous uncomplicated cesarean section in the Obstetrics Department at a University Hospital.</p></div><div><h3>Material and methods</h3><p>We performed an observational, longitudinal, prospective, descriptive, non-blind, comparative study of patients with a history of previous cesarean sections who attended a tertiary care teaching hospital in northeastern México for the care of their pregnancy from March 2013 to July 2014, where they were monitored during labor. A descriptive statistic, with a <em>p</em>-value significance and a Chi-squared analysis, was applied.</p></div><div><h3>Results</h3><p>Three hundred patients attended the hospital, with 119 (39.6%) vaginal deliveries and 181 (60.3%) C-sections. The most common indication of a previous cesarean section was a narrow pelvic outlet in 59 patients (19.6%). There were more vaginal births in patients with cervical dilatation >4<!--> <!-->cm and previous vaginal births. Fetal weight >3500<!--> <!-->g, absence of previous vaginal birth, cervical dilatation <3.5<!--> <!-->cm and gestational age >40 weeks increase the risk of a cesarean section.</p></div><div><h3>Conclusion</h3><p>Labor in women with uncomplicated previous cesarean sections is a useful clinical behavior, allowing an uncomplicated delivery in 39.6% of cases.</p></div>","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"19 77","pages":"Pages 166-169"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmu.2017.10.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91746859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hematopoietic stem cell transplants for persons with multiple sclerosis: Is this the best therapeutic option?","authors":"G.J. Ruiz-Argüelles , D. Gomez-Almaguer","doi":"10.1016/j.rmu.2017.10.003","DOIUrl":"https://doi.org/10.1016/j.rmu.2017.10.003","url":null,"abstract":"","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"19 77","pages":"Pages 208-209"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmu.2017.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136704282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effective medicine and the economy","authors":"D. Gómez-Almaguer, J.C. Jaime-Pérez","doi":"10.1016/j.rmu.2017.08.001","DOIUrl":"10.1016/j.rmu.2017.08.001","url":null,"abstract":"","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"19 76","pages":"Pages 109-110"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmu.2017.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87816782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Actinomycetoma by Nocardia brasiliensis: A neglected disease and a surprising laboratory for experimental medicine","authors":"M.C. Salinas-Carmona","doi":"10.1016/j.rmu.2017.07.001","DOIUrl":"10.1016/j.rmu.2017.07.001","url":null,"abstract":"","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"19 76","pages":"Pages 143-144"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmu.2017.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81495706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Torres Aguilar , R.J. Maya Quintá , G. Rodríguez Prieto , M. Leal , J.F. Castilleja Leal
{"title":"Early initiation of renal replacement therapy in acute renal injury","authors":"O. Torres Aguilar , R.J. Maya Quintá , G. Rodríguez Prieto , M. Leal , J.F. Castilleja Leal","doi":"10.1016/j.rmu.2017.10.004","DOIUrl":"10.1016/j.rmu.2017.10.004","url":null,"abstract":"<div><p>Acute kidney injury (AKI) is a widely-seen pathology in the hospital environment. Today, prevention is the best available treatment. Nowadays, one of the most common causes is sepsis-induced AKI, which is seen in critical care patients. Sepsis-induced AKI includes in its pathophysiology injury associated with low kidney perfusion and toxicity caused by inflammatory biomarkers but has a more complex treatment.</p><p>There is not yet a consensus of when to initiate renal replacement therapy, but it seems that early initiation confers a better prognosis, as well as that continuous renal therapy, could have an impact on life expectancy and early renal recovery. We analyze epidemiology, pathophysiology, and treatment in the following article, particularly the early initiation of renal replacement therapy in sepsis-induced AKI.</p></div>","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"19 76","pages":"Pages 131-139"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmu.2017.10.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74447163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between peripheral arterial disease and diabetic foot ulcers in patients with diabetes mellitus type 2","authors":"M.Á. Tresierra-Ayala, A. García Rojas","doi":"10.1016/j.rmu.2017.07.002","DOIUrl":"10.1016/j.rmu.2017.07.002","url":null,"abstract":"<div><h3>Background</h3><p>Diabetic foot ulcer (DFU) is a chronic complication of diabetes mellitus. It is reported that diabetes is associated with a two to four-fold increase in the incidence of peripheral arterial disease (PAD) compared to non-diabetic subjects. Peripheral arterial disease (PAD) may play a role in the etiology of foot ulceration in patients with diabetes mellitus.</p></div><div><h3>Objective</h3><p>To determine the association between peripheral arterial disease and diabetic foot ulcers in patients with type II diabetes mellitus.</p></div><div><h3>Methods</h3><p>A cross-sectional study was carried out at Hospital Belen of Trujillo, which all patients with type 2 diabetes mellitus ≥50 years were included. Presence or absence of both variables was measured in our study.</p></div><div><h3>Results</h3><p>Three hundred twenty-two patients were included in the study. We found that 129 patients had peripheral arterial disease and diabetic foot ulcers (OR 3, 95% IC 1.087–8.242 and <em>p</em> <!--><<!--> <!-->0.001).</p></div><div><h3>Conclusions</h3><p>In this study, peripheral arterial disease was associated with diabetic foot ulcer in patients with type 2 diabetes mellitus.</p></div>","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"19 76","pages":"Pages 123-126"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmu.2017.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75242505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P.P. Flores-Garza, Ó.A. García-Espinoza, K. Salas-Longoria, Ó. Salas-Fraire
{"title":"Association between ischiotibial muscle flexibility, functional capacity and pain in patients with knee osteoarthritis","authors":"P.P. Flores-Garza, Ó.A. García-Espinoza, K. Salas-Longoria, Ó. Salas-Fraire","doi":"10.1016/j.rmu.2017.06.001","DOIUrl":"10.1016/j.rmu.2017.06.001","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the association between flexibility of the ischiotibial muscles, function and pain in patients with knee osteoarthritis (OA).</p></div><div><h3>Methods</h3><p>A total of 33 patients of both genders with an age greater than or equal to 40 years, clinically diagnosed with osteoarthritis in one or both knees with radiographic evidence of the disease, were recruited and evaluated. Participants underwent the WOMAC questionnaire, along with measurements of flexibility using a Lafayette flexometer and the Back Saver Sit and Reach test. The correlation between the WOMAC questionnaire and its three components (pain, stiffness and functional limitation) was recorded. Total flexibility was obtained from the mean measurement of both knees.</p></div><div><h3>Results</h3><p>A statistically significant correlation between the global WOMAC score and flexibility was found (−0.38, <em>p</em> <!-->=<!--> <!-->0.02). When the components were analyzed separately, a statistically significant correlation between total flexibility and functional limitation (−0.40, <em>p</em> <!-->=<!--> <!-->0.01) was evident; however, this was not so with the components of pain and stiffness.</p></div><div><h3>Conclusions</h3><p>Greater ischiotibial flexibility reduces pain, stiffness, and significant functional limitation in patients with knee OA. These results show that it is important to prescribe flexibility exercises during physical therapy in these patients.</p></div>","PeriodicalId":34640,"journal":{"name":"Medicina Universitaria","volume":"19 76","pages":"Pages 111-114"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmu.2017.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73213051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}