Hanyang Medical Reviews最新文献

{"title":"Artificial Intelligence in Medicine","authors":"Jihoon Jeong","doi":"10.7599/HMR.2017.37.2.47","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.2.47","url":null,"abstract":"• AI-based clinical decision making • Medical knowledge engineering • Knowledge-based and agent-based systems • Computational intelligence in bioand clinical medicine • Intelligent medical information systems • AI in medical education • Intelligent devices and instruments • Automated reasoning and metareasoning in medicine • Methodological, philosophical, ethical, and social issues of AI in medicine","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133452409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introduction of Artificial Intelligence in Pathology","authors":"S. Song","doi":"10.7599/HMR.2017.37.2.77","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.2.77","url":null,"abstract":"","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"413 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123564899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overview of symptoms, pathogenesis, diagnosis, treatment, and prognosis of various acquired polyneuropathies","authors":"Hyun-Jung Yu, S. Koh","doi":"10.7599/HMR.2017.37.1.34","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.1.34","url":null,"abstract":"Polyneuropathy means a lot of diseases affecting peripheral nerves showing roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain [1]. Pathogenesis causing polyneuropathy usually begins in the hands and feet and progresses to the arms and legs [1]. Sometimes it can involve other parts of the body such as the autonomic nervous system. Uncountable causes can induce acute or chronic polyneuropathy, so finding the original cause is most important for the treatment of polyneuropathy. Polyneuropathies are classified in different ways depending on cause, presentation, or classes of polyneuropathy (for example, the axon, the myelin sheath, or the cell body). Among these classifications, the classification based on classes of polyneuropathy can explain the pathogenesis and symptoms at the same time. Polyneuropathy in the axon is called distal axonopathy which is the result of interrupted function of the peripheral nerves and the most common response of neurons to metabolic or toxic disturbances, such as diabetes, kidney failure, connective tissue disease, deficiency syndrome, alcoholism, chemotherapy, and so on. People with distal axonopathy frequently present with sensorimotor disturbances. Disease in the myelin sheath is myelinopathy characterized with a loss of myelin or of the Schwann cells. This demyelination disturbs the conduction of action potentials through the axon of the nerve cells. Among various diseases causing myelinopathy, the most common one is acute inflammatory demyelinating polyneuropathy (AIDP). Damage of neurons in the peripheral nervous system results in neuronopathy. Neuronopathies can Corresponding Author: Seong-Ho Koh Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine, 153 Gyeongchun-ro, Guri 11923, Korea Tel: +82-31-560-2267 Fax: +82-31-560-2267 E-mail: ksh213@hanyang.ac.kr","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121841147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutting Edge Technologies in Otology Field","authors":"J. Chung, Seung Hwan Lee","doi":"10.7599/HMR.2017.37.1.25","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.1.25","url":null,"abstract":"With the recent breakthrough of science and technology, revolutionary changes are taking place in the medical environment. There has been much progress in the field of otology. Recently, endoscopic ear surgery technique has expanded the application and scope of the technique [1,2]. The development of information technology (IT) also affects medical education systems. Surgical training and medical education adapt virtual reality simulation to increase education outcome over the traditional teaching methods [3]. Recently, hearing aids have adapted the emerging technology of “internet of things” to create an environment where the hearing loss patients can hear more [4]. In addition, artificial intelligence technology is gradually applied in the otology field. Machine learning, one of the artificial intelligence techniques, could help to explore the unknown areas of otology. The authors try to introduce the cutting-edge techniques used in the otology field and discuss about the future direction of medical science.","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127436237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Gestational Diabetes Mellitus","authors":"S. Yu","doi":"10.7599/HMR.2017.37.1.30","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.1.30","url":null,"abstract":"","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122004033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review and update for central serous chorioretinopathy","authors":"Y. Shin","doi":"10.7599/HMR.2017.37.1.10","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.1.10","url":null,"abstract":"Central serous chorioretinopathy (CSC) is characterized by the accumulation of subretinal fluid (SRF) at the posterior pole of the retina, which leads to mild to moderate visual disturbance [1]. It was first described as central recurrent retinitis by Albrecht von Graefe in 1866 [2]. In 1965, Maumenee found that macular serous detachment was due to an abnormal leak from retinal pigment epithelium (RPE) through fluorescein angiography (FA) [3] and thereafter, Gass used the term “central serous chorioretinopathy” for the first time [4]. CSC is the fourth most common macular disease following agerelated macular degeneration, diabetic retinopathy and retinal vein occlusion, but it is an important clinical issue due to its common incidence seen in the productive age group (young and middle-aged adults) [5]. CSC is an old and well-known disease, however, the exact pathogenesis is still unknown. With the recent introduction of advanced imaging techniques, more improved understanding of CSC is possible and subsequently, better treatment modalities have also been suggested. This article describes a general overview and recent clinical issues of CSC.","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121984979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent trend of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) management","authors":"Seung Wook Lee","doi":"10.7599/HMR.2017.37.1.40","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.1.40","url":null,"abstract":"Lower urinary tract symptoms (LUTS) and pelvic pain caused by diseases of the prostate have decreased the quality of life in men. Epidemiologic studies report that the prevalence of prostatitis-like symptoms is approximately similar to diabetes mellitus and ischemic heart disease. The rate of prostatitis-like symptoms was reported to range from 2.2% to 9.7%, and mean prevalence was 8.2% [1]. Prostatitis is a relatively common disease seen in the field of urology that reduces the quality of life of men in many ways. The National Institutes of Health (NIH) published that there are four categories in prostatitis, among which chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) corresponds to category III. According to the recommendation of the International Association for the Study of Pain, chronic pelvic pain syndrome and prostate pain syndrome have a similar definition and they are widely used recently [2]. A valid tool which can be used to assess CP/CPPS was developed as represented by the National Institutes of Health chronic prostatitis symptom index (NIH-CPSI) [3]. A previous study revealed that the prevalence of NIH-CPSI for the assessment of CP/CPPS is about 8%–10% [4]. Only 20 years ago, collecting prostatic secretion was performed to obtain bacterial culture, to confirm and treat bacterial causes of chronic prostatitis. Also, antibiotic treatment was prescribed for such symptoms [5]. In 1995, the Korea National Institute of Health announced clarification for prostatitis at the Diabetes and Digestive and Kidney Diseases (NIDDK) consensus meeting. However, Recent trend of chronic prostatitis/ chronic pelvic pain syndrome (CP/CPPS) management","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115835360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The first-line regimens of Helicobacter pylori eradication in Korea","authors":"C. Park","doi":"10.7599/HMR.2017.37.1.2","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.1.2","url":null,"abstract":"Approximately half of the world’s population is infected by Helicobacter pylori [1], which causes various gastrointestinal diseases including gastritis, peptic ulcer, gastric mucosaassociated lymphoid tissue lymphoma, and gastric cancer [2,3]. Korean guidelines, which were revised in 2013, by the Korean College of Helicobacter and Upper Gastrointestinal Research strongly recommend that H. pylori should be eradicated in patients with peptic ulcer disease, gastric MALT lymphoma, endoscopically treated early gastric cancer, and immune thrombocytopenic purpura [4]. Identification of optimal regimen of H. pylori eradication has been a challenge for gastroenterologists. Twenty years ago, one comparative study showed that proton pump inhibitor (PPI)based triple therapy, that consisted of PPI, amoxicillin, and metronidazole, had superior efficacy for H. pylori eradication among various regimens based on PPI, bismuth, amoxicillin, and metronidazole [5]. In addition, conventional triple therapy, that consists of PPI, amoxicillin, and clarithromycin, has been widely used in Korea because of the high resistance rate of H. pylori against metronidazole [4,6,7]. This conventional triple therapy for 7-14 days is also a world-wide choice for H. pylori eradication [8,9]. However, eradication of conventional triple therapy has decreased over the past 10 years [10,11], caused by resistance against clarithromycin [12]. Alternatively, many eradication regimens including sequential therapy, concomitant therapy, and hybrid therapy have been suggested [4]. Despite of the insufficient eradication rate of the conventional triple therapy, the current Korean guideline still recommends conventional triple therapy as a first-line therapy for H. pylori infection because superior efficacy of alternative regimens over the conventional triple therapy has not been fully evaluated [4]. Recently, however, the Maastricht V/Florence Consensus Report stated that PPI-clarithromycin-containing triple therapy without prior susceptibility testing should be abandoned Corresponding Author: Chan Hyuk Park Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, 153 Gyeongchun-ro, Guri, 11923, Korea. Tel: +82-31-560-2230 Fax: +82-31-553-7369 E-mail: yesable7@gmail.com","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114111091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of PI3K/AKT pathway and its therapeutic possibility in Alzheimer's disease","authors":"Hyun-Jung Yu, S. Koh","doi":"10.7599/HMR.2017.37.1.18","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.1.18","url":null,"abstract":"","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134501843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current update in diverse diseases","authors":"S. Koh","doi":"10.7599/HMR.2017.37.1.1","DOIUrl":"https://doi.org/10.7599/HMR.2017.37.1.1","url":null,"abstract":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited In this edition, seven outstanding experts described updates on various diseases which are their major interests. First of all, Dr. Park, who majors in gastrointestinal internal medicine, discussed the first-line regimens of Helicpbacter pylori eradication in Korea [1]. His article is thought to be very helpful for many other doctors because he is dealing with various regimens for the eradication of Helicpbacter pylori. Second, Dr. Shin talked about central serous chorioretinopathy (CSC) in his review and he especially showed new imaging findings and treatments of CSC [2]. This article will definitely help many ophthalmologists. Third, Dr. Koh wrote the role of the PI3K/Akt pathway and its therapeutic possibility in Alzheimer’s disease (AD). In this article, he described the importance of the signaling pathway in AD. His review will improve readers’ understanding on the relationship between the PI3K/Akt pathway and AD [3]. Fourth, Dr. Jung who is an expert on otology wrote cutting edge technologies on the otology field and reviewed their usefulness for patients with ear problems [4]. Fifth, Dr. Yu concisely talked about gestational diabetes mellitus (GDM) and how to deal with GDM [5]. He emphasized the importance of GDM to reduce the complications of GDM mother and the offspring. Sixth, in another article, Dr. Yu extensively reviewed symptoms, pathogenesis, diagnosis, treatment, and prognosis of various acquired polyneuropathies [6]. Her article will give a hand to neurologists in understanding several kinds of acquired polyneuropathies in terms of differential diagnosis and treatments. Last but not least, Dr. Lee discussed the recent trend of chronic prostatitis/chronic pelvic pain syndrome (CP/ CPPS) management, especially focused on the new concept of treatment “UPOINT”. Although the concept of UPOINT needs to be confirmed through randomized controlled trials, it looks very helpful for the patients with CP/CPPS at the current stage [7]. As described in this editorial, seven experts faithfully described several important topics and all these are considered to be helpful for the readers with various interests.","PeriodicalId":345710,"journal":{"name":"Hanyang Medical Reviews","volume":"2 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128248942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}