{"title":"Differentiated approach in the treatment of hemorrhagic stroke","authors":"Sh. A. Turdiboev, R. Berdiev, B. A. Rahmonov","doi":"10.52888/0514-2515-2022-354-3-55-60","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-354-3-55-60","url":null,"abstract":"Aim. To improve the results of patients’ treatments with hemorrhagic stroke.Materials and methods. The results of the treatments of the 156 patients with hemorrhagic strokes were analyzed, among them 85 (55,5%) men and 71 (44,5%) women. The ages of the patients varied from 18 to 78.Results and discussions. According to the location of the non-traumatic intracerebral hematoma, they were distributed in the following way: in the frontal lobe -11 (7.1%), in the occipital lobe - 8 (5,1%), in the hemispheres of the cerebellum -15 (9/6%), in the ventricles of the brain -26 (16.7%) and the parietotemporal lobes - 96 (61,5%). In 25 cases patients were delivered in a conscious state (GCS-15 points) 28 injured patients were moderately stunned (GCS-13 points), deep stun was observed in 36 (23.1%) patients (GCS-12 points), soporific consciousness was observed in 31 (19.8%) patients (GCS-9 points), moderate coma in 27 (17.3%) cases (GCS-7points) and in 9 (5.8%) patients it was rated as a deep coma (GCS-6 point).Conclusion. Neuroimaging bean methods of the survey give an opportunity to adequately evaluate tactics for treating patients with intracerebral hematoma. The differentiated approach in treating patients with hemorrhagic strokes positively affects the result of the given category of patients.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125185176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The significance of overweight and visceral obesity in the detection of pregestational diabetes in the population of women of reproductive age in Dushanbe","authors":"S. Anvarova, M. S. Jaborova","doi":"10.52888/0514-2515-2022-354-3-12-16","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-354-3-12-16","url":null,"abstract":"Materials and research methods. We examined 1,500 women living in the city of Dushanbe for the period 2020-2021. The examination was carried out at the bases of medical health centers in the city of Dushanbe. In the course of the study, in order to clarify the risk factors in the development of pregestational diabetes, we measured the weight, height of patients, waist circumference (WC), hip circumference (OB), calculated the ratio OT / OB, and also conducted a survey of all examined women.Results of the study and their discussion. In particular, 8 cases of type 1 diabetes mellitus, 92 cases of type 2 diabetes mellitus and 2 cases with suspected MODY diabetes. In the course of the study, it should also be noted that the leading risk factor for the development of type 2 diabetes mellitus in particular (in 60% of cases) was overweight and, in particular, visceral obesity. The average level of glycated hemoglobin in the group of identified patients with type 1 diabetes mellitus was 7.7±0.8%. The age of the examined is 35.7±4.1 years. The average level of glycated hemoglobin in the group of patients with type 2 diabetes was 7.5±0.9%. In addition, during the study, an increase in the level of insulin in the blood of overweight and obese patients by an average of 15.2 mIU / l was found. When calculating the HOMA index, a significant (p<0.01) increase was noted, mainly in the group of patients with overweight and obesity.Conclusion. Taking into account the obtained results, the leading role of overweight and visceral obesity in the detection of pregestational diabetes is shown.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130971570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Darovskikh, P. Shonazarov, N. V. Vdovina, Y. Shishkova, I. Prokopov
{"title":"Technology for the treatment of human diseases based on the use of simulated microwave radiation from the sun","authors":"S. Darovskikh, P. Shonazarov, N. V. Vdovina, Y. Shishkova, I. Prokopov","doi":"10.52888/0514-2515-2022-354-3-26-34","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-354-3-26-34","url":null,"abstract":"Aim. Substantiation of the most probable reason for the increase in viral activity and disclosure of the main content of nature-like technology for the treatment of human diseases using simulated microwave radiation from the Sun reaching the Earth’s surface.Materials and methods. A description of the hardware and software tools for simulating solar microwave radiation is given, which makes it possible to simulate “bursts” of solar microwave radiation from several seconds to tens of minutes, both with linear and chaotic polarization in the frequency range of 4.0–4.3 GHz. In this case, the amplitude spectrum of such radiation can vary in width, shape, and intensity, which does not exceed 100 μW/cm2.Results and discussion. The mechanism of the corrective action of the above radiation on the human body is studied. It is associated with the conversion of electromagnetic energy absorbed by the body into the energy of lowintensity broadband elastic oscillations. This makes it possible to activate inactivated enzyme complexes under hypoxic conditions to restore the free energy potential in cellular structures.Conclusions. The evidence on the validity of the use of this radiation against inflammation at the clinical, preclinical, and microbiological levels gives grounds for predicting that it will also be effective in human viral diseases.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131650366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical features of the course and new approaches to the treatment of intrauterine viral and bacterial infections in newborns","authors":"M. Yusupova","doi":"10.52888/0514-2515-2022-354-3-78-82","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-354-3-78-82","url":null,"abstract":"Aim. To study the clinical features of the course and new approaches to the treatment of intrauterine viral and bacterial infections in newborns.Materials and methods. Clinical features of the course and new approaches to the treatment of intrauterine viral and bacterial infections in 98 newborns were studied based on the state institution of the National Medical Center of the Republic of Tajikistan “Shifobakhsh” in the Department of neonatal pathology.Results and discussion. We examined 98 patients with intrauterine viral and bacterial infections, which made up the main group, and 20 patients of the control group of the study. The diagnosis of intrauterine viral-bacterial infections of newborns was verified based on serological and immunological, clinical, biochemical, and bacteriological studies of blood and loci.Conclusion. The use of specific therapy in combination with metabolic agents and immunocoregulatory therapy in patients with intrauterine viral and bacterial infections leads to a faster positive dynamic of the main clinical manifestations of the disease.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"197 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132718191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perioperative intra-abdominal pressure parameters for different surgical techniques in patients with ventral hernias","authors":"Sh. N. Shamsullozoda, J. Abdullozoda","doi":"10.52888/0514-2515-2022-354-3-72-77","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-354-3-72-77","url":null,"abstract":"Aim. To study perioperative IAP parameters with various methods of hernioplasty in patients with ventral hernias.Materials and research methods. The results of the treatment of 148 patients with ventral hernias were studied. The first group included 58 patients for whom an anterior separation plasty was used for hernioplasty. The second group included 44 patients who underwent posterior separation of the abdominal wall muscles. The third group consisted of 46 patients who underwent onlay (n=28) and sublay (n=18) methods of hernioplasty.Results and discussion. In patients with W3 hernias, when closing the edges of the hernia orifice, there was a significant increase in IAP to a level corresponding to the I degree of intra-abdominal hypertension, which averaged 12.8±1.9 mm Hg (p<0.05). In patients with W4 hernias, the level of intra-abdominal pressure after closing the edges of the hernia orifice was significantly higher than in patients with W3 hernias, and on average they were 14.7±1.7 mm Hg. (p<0.05), which corresponded to the upper limit of the I degree of intra-abdominal pressure.Conclusion. The results of perioperative monitoring of intra-abdominal pressure indicate the tension nature of onlay and sublay hernioplasty methods, and therefore their use in hernias of W3 and W4 sizes is contraindicated. For large and giant hernias, the use of separation methods of hernioplasty is recommended.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133474145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. M. Akhmadzoda, F. Rahimi, F. R. Odinaev, B. J. Safarov, A. M. Solihzoda, Z. S. Tagoybekov, I. Azímov, Sh. I. Hodiev, A. T. Homidov, I. R. Abdurahimov, K. O. Boboev
{"title":"Possibilities of cryosurgery in the treatment of the abdominal cavity diseases","authors":"S. M. Akhmadzoda, F. Rahimi, F. R. Odinaev, B. J. Safarov, A. M. Solihzoda, Z. S. Tagoybekov, I. Azímov, Sh. I. Hodiev, A. T. Homidov, I. R. Abdurahimov, K. O. Boboev","doi":"10.52888/0514-2515-2022-354-3-17-26","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-354-3-17-26","url":null,"abstract":"Aim. To study the immediate results of the use of cryosurgical instruments and ultra-low temperature liquid nitrogen in diseases of abdominal organs.Materials and research methods. The article presents the results of surgical treatment using ultra-low temperature liquid nitrogen (196oC) for 308 patients with diseases of the abdominal organs in the Department of Liver and Pancreas Surgery of the Institute of Gastroenterology of the Republic of Tajikistan from 2016 to 2022.The results and discussion. The authors proposed an algorithm for the use of the ultra-low temperature of liquid nitrogen in the treatment of diseases of the abdominal organs after the development of the latest cryogenic equipment. It turned out that the resulting cryodestruction leads to the death of parasitic elements of alveococcosis, echinococcosis, and liver tuberculosis, as well as to cytolysis of atypical calls in hepatocellular carcinoma. The most important advantage of liver cryosurgery, especially in concomitant chronic viral hepatitis and liver cirrhosis, is a reliable parenchymal haemo-and cholestasis, a decrease in intraoperative blood loss, an increase in the radicality of an operation, and reliable prevention of intraoperative dissemination of malignant and parasitic diseasesConclusion. The accumulated experience of surgeries for various diseases of the abdominal organs using ultra-low temperature liquid nitrogen allows concluding that cryosurgery of the abdominal organs has an undoubted prospect. The positive characteristic of using cryotechnology in the treatment of severe diseases of abdominal organs suggests that it is advisable to introduce the method into clinical practice on a wide scale.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129139233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-treatment survival rate of uterine corpus cancer patients","authors":"N. Z. Muhamadi","doi":"10.52888/0514-2515-2022-354-3-47-55","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-354-3-47-55","url":null,"abstract":"Aim. To study the post-treatment survival of patients with uterine body cancer depending on a parity and the metabolic syndrome.Material and methods. 218 patients with a proven diagnosis of uterine body cancer, who were examined and treated at the State Institution “Republican Oncological Research Center” of the MoHSP of RT, for the period from 2007 to 2019, participated in the study. All patients, depending on the parity, were divided into groups: multiparous (n=101), low-parous (n=84), and infertile (n=33). Survival rate was measured using the Kaplan-Meier curve comparison using the Cox F-test, and differences were considered statistically significant at p<0.05.Results. An analysis of the overall cumulative post-treatment survival of uterine body cancer patients by the KaplanMeier method showed that 55% of patients are alive 60 months after the treatment, and 48% of patients after 85 months. Survival rates in the group of women with multiple births are better than in the group of women with few births (55% of women with multiple births and 45% of women with few births lived for 70 months). But these differences are not statistically significant (p>0.05). The lowest survival rates are observed in the group of low-birth-weight uterine body cancer patients with metabolic syndrome, and the best rates are in the group of multiparous patients without metabolic syndrome although the difference was not statistically significant (p>0.05).Conclusion. The analysis of the survival of patients with uterine body cancer in the region of high birth rate using the Kaplan-Meier method showed that the survival of patients with uterine body cancer depends not only on the stage of the disease and methods of therapy but also on the parity and concomitant extragenital pathology, such as metabolic syndrome.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125623930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nutritional status of students in the city of Dushanbe","authors":"H. S. Khayrov, O. B. Raҳmonaliev","doi":"10.52888/0514-2515-2022-354-3-60-65","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-354-3-60-65","url":null,"abstract":"Aim. To study the nutritional status of students of higher educational institutions in Dushanbe.Materials and methods. The study focuses on the nutritional status of 498 university students aged 18-29 living in Dushanbe in 2022. Among those examined were 246 male students (49.4%) and 252 female students (50.6%). Statistical analysis of the collected data was conducted using the computer program Tj_AssNut. The program automatically determined the body mass index, protein-energy deficiency, and the degree of obesity.Results and discussion. The results show that 6.22% of the examined individuals had a BMI <18.5, indicating the presence of protein-energy deficiency. The rate of normal nutritional status in the surveyed populations was 78.92%. 10.24% of the respondents are overweight, and 4.62% (5.16% women and 4.07% men) are obese.Conclusions. The study of the nutritional status of students of educational institutions of Dushanbe shows that among all the students examined 6.22% have protein-energy deficiencies, 78.92% are in normal nutritional status, 10.24% have increased body weight and 4.62% are obese.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131494580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Significance of oxidative endotoxemia and hypoxia in the pathogenesis of testicular insufficiency in patients with inguinal hernia","authors":"J. Abdullozoda, I. Gadoev, M. H. Nabiev","doi":"10.52888/0514-2515-2022-354-3-5-11","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-354-3-5-11","url":null,"abstract":"Aim. To determine the level of “oxidative stress” and hypoxia markers in the blood and venous blood flowing from the testicle in inguinal hernias and the postoperative period after inguinal hernioplasty.Materials and Methods. 34 patients with inguinal hernias were under the observation in Istiqlol health complex of Dushanbe. The age of patients ranged from 18 to 30 years old. The patients were divided into 3 groups: 14 patients with long (5 or more years) inguinal hernia combined with varicocele, 12 patients with infertility, and 8 patients with inguinal herniotomy. The content of LPO products and hypoxia markers in the blood flowing from the testicle was studied in 34 patients with various groups of inguinal hernias.Results and discussion. An analysis of the level of “oxidative” toxemia and hypoxia indices in the studied groups of patients showed their increased levels in the peripheral blood. The levels of DA and MDA in peripheral blood in Group I patients reached 1.3±0.02 units pg/ml and 2.4±0.09 nmol/ml, which was caused by prolonged compression of the spermatic cord elements by the hernial sac; the presence of ischemia was confirmed by increased blood lactate level. Marked pathophysiological changes result in the disturbance of hormonal background and spermatogenesis disorder.Conclusion. Increased content of LPO products in the testicular parenchyma further results in the branching of chain reactions and final LPO products with high damaging activity followed by the development of systemic damage to cellular structures of the contralateral testis with subsequent progression and development of testicular insufficiency.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134029661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On the 40th anniversary of the discovery of Helicobacter pylori","authors":"V. Reshetnyak, A. I. Burmistrov","doi":"10.52888/0514-2515-2022-353-2-121-134","DOIUrl":"https://doi.org/10.52888/0514-2515-2022-353-2-121-134","url":null,"abstract":" The review is dedicated to the analysis of the accumulated data on the study of Helicobacter pylori (H. pylori) since the detailed description of this bacterium as the main etiological factor of gastrointestinal diseases. The work shows the dual role of H. pylori both as a bacterial pathogen for humans and as a potential representative of the normal microbiome of the stomach. In most scientific publications, the attention of researchers is focused entirely on the consideration of the pathogenic properties of H. pylori in the development of chronic gastritis, peptic ulcer disease (PUD) and gastric cancer (GC), and also considers the development of effective methods of eradication therapy. Along with this, in recent years, more and more often there are works that indicate a potentially positive effect of this bacterium on the human body and the occurrence of a number of negative consequences after eradication therapy. In this connection, the question of the probable affiliation of H. pylori to the composition of the human microbiome is discussed. Data on the high prevalence of the microorganism in the population and its asymptomatic coexistence with humans indicate the persistence of the bacterium in the body, most likely as a representative of the microbiome. The accumulated data on the effect of H. pylori on human health demonstrate a clear ambiguity of the problem. In this regard, it is important to answer the question whether it is necessary to create programs for mass eradication of H. pylori, or whether it is necessary to approach the implementation of eradication therapy in a more personalized way.","PeriodicalId":345517,"journal":{"name":"Health care of Tajikistan","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131115172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}