Journal of Chest Surgery最新文献

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Mitral Valve Replacement for Bulky, Calcified Mitral Annulus: A Case Report. 二尖瓣瓣环肥大、钙化的二尖瓣置换术:病例报告。
Journal of Chest Surgery Pub Date : 2024-09-05 Epub Date: 2024-06-05 DOI: 10.5090/jcs.24.017
Yusuke Nakata, Kazuyuki Miyamoto
{"title":"Mitral Valve Replacement for Bulky, Calcified Mitral Annulus: A Case Report.","authors":"Yusuke Nakata, Kazuyuki Miyamoto","doi":"10.5090/jcs.24.017","DOIUrl":"10.5090/jcs.24.017","url":null,"abstract":"<p><p>Calcification of the mitral valve annulus is common in patients on dialysis. The growing number of individuals receiving dialysis has been accompanied by an increase in cases necessitating surgical intervention for mitral valve annulus calcification. In this report, we present a severe case characterized by bulky calcification of the mitral annulus, which was managed with mechanical mitral valve replacement. A 61-year-old man on dialysis presented with chest pain upon exertion that had persisted for 3 months. Cardiac echocardiography revealed severe mitral stenosis and regurgitation, accompanied by cardiac dysfunction. During surgery, an ultrasonic aspiration system was employed to remove the calcification of the mitral valve annulus to the necessary extent. Subsequently, a mechanical mitral valve was sutured into the supra-annular position. To address the regurgitation, the area surrounding the valve was sewn to the wall of the left atrium. Postoperative assessments indicated an absence of perivalvular leak and demonstrated improved cardiac function. The patient was discharged on postoperative day 22. We describe a successful mitral mechanical valve replacement in a case of extensive circumferential mitral annular calcification. Even with severe calcification extending into the left ventricular myocardium, we were able to minimize the decalcification process. This approach enabled the performance of mitral mechanical valve replacement in a high-risk patient on dialysis, thus expanding the possibilities for cardiac surgery.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":" ","pages":"496-499"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Different DLCO Parameters as Predictors of Postoperative Pulmonary Complications in Mild Chronic Obstructive Pulmonary Disease Patients with Lung Cancer. 不同的 DLCO 参数是轻度慢性阻塞性肺病肺癌患者术后肺部并发症的预测指标。
Journal of Chest Surgery Pub Date : 2024-09-05 Epub Date: 2024-08-08 DOI: 10.5090/jcs.24.010
Mil Hoo Kim, Joonseok Lee, Joung Woo Son, Beatrice Chia-Hui Shih, Woohyun Jeong, Jae Hyun Jeon, Kwhanmien Kim, Sanghoon Jheon, Sukki Cho
{"title":"Different DL<sub>CO</sub> Parameters as Predictors of Postoperative Pulmonary Complications in Mild Chronic Obstructive Pulmonary Disease Patients with Lung Cancer.","authors":"Mil Hoo Kim, Joonseok Lee, Joung Woo Son, Beatrice Chia-Hui Shih, Woohyun Jeong, Jae Hyun Jeon, Kwhanmien Kim, Sanghoon Jheon, Sukki Cho","doi":"10.5090/jcs.24.010","DOIUrl":"10.5090/jcs.24.010","url":null,"abstract":"<p><strong>Background: </strong>Numerous studies have investigated methods of predicting postoperative pulmonary complications (PPCs) in lung cancer surgery, with chronic obstructive pulmonary disease (COPD) and low forced expiratory volume in 1 second (FEV<sub>1</sub>) being recognized as risk factors. However, predicting complications in COPD patients with preserved FEV<sub>1</sub> poses challenges. This study considered various diffusing capacity of the lung for carbon monoxide (DL<sub>CO</sub>) parameters as predictors of pulmonary complication risks in mild COPD patients undergoing lung resection.</p><p><strong>Methods: </strong>From January 2011 to December 2019, 2,798 patients undergoing segmentectomy or lobectomy for non-small cell lung cancer (NSCLC) were evaluated. Focusing on 709 mild COPD patients, excluding no COPD and moderate/severe cases, 3 models incorporating DL<sub>CO</sub>, predicted postoperative DL<sub>CO</sub> (ppoDL<sub>CO</sub>), and DL<sub>CO</sub> divided by the alveolar volume (DL<sub>CO</sub>/VA) were created for logistic regression. The Akaike information criterion and Bayes information criterion were analyzed to assess model fit, with lower values considered more consistent with actual data.</p><p><strong>Results: </strong>Significantly higher proportions of men, current smokers, and patients who underwent an open approach were observed in the PPC group. In multivariable regression, male sex, an open approach, DL<sub>CO</sub> <80%, ppoDL<sub>CO</sub> <60%, and DL<sub>CO</sub>/VA <80% significantly influenced PPC occurrence. The model using DL<sub>CO</sub>/VA had the best fit.</p><p><strong>Conclusion: </strong>Different DL<sub>CO</sub> parameters can predict PPCs in mild COPD patients after lung resection for NSCLC. The assessment of these factors using a multivariable logistic regression model suggested DL<sub>CO</sub>/VA as the most valuable predictor.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":" ","pages":"460-466"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary: Comparative Study of Indocyanine Green Intravenous Injection and the Inflation-Deflation Method for Assessing Resection Margins in Segmentectomy for Lung Cancer: A Single-Center Retrospective Study. 评论:吲哚青绿静脉注射与充气-放气法评估肺癌分段切除术切缘的比较研究:单中心回顾性研究
Journal of Chest Surgery Pub Date : 2024-09-05 Epub Date: 2024-08-01 DOI: 10.5090/jcs.24.061
Chang Young Lee
{"title":"Commentary: Comparative Study of Indocyanine Green Intravenous Injection and the Inflation-Deflation Method for Assessing Resection Margins in Segmentectomy for Lung Cancer: A Single-Center Retrospective Study.","authors":"Chang Young Lee","doi":"10.5090/jcs.24.061","DOIUrl":"10.5090/jcs.24.061","url":null,"abstract":"","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":" ","pages":"458-459"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary: Thoracic Endometriosis: The Necessity of a Multidisciplinary Approach for Optimal Treatment. 评论:胸腔子宫内膜异位症:采用多学科方法进行最佳治疗的必要性。
Journal of Chest Surgery Pub Date : 2024-09-05 DOI: 10.5090/jcs.24.079
Jae Hoon Lee
{"title":"Commentary: Thoracic Endometriosis: The Necessity of a Multidisciplinary Approach for Optimal Treatment.","authors":"Jae Hoon Lee","doi":"10.5090/jcs.24.079","DOIUrl":"10.5090/jcs.24.079","url":null,"abstract":"","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":"57 5","pages":"490-491"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary: Preoperative versus Intraoperative Tissue Diagnosis in Highly Suspicious Stage I Lung Cancer: Which Is the Superior Approach? 评论:高度可疑 I 期肺癌的术前组织诊断与术中组织诊断:哪种方法更优越?
Journal of Chest Surgery Pub Date : 2024-09-05 Epub Date: 2024-08-08 DOI: 10.5090/jcs.24.074
Jeong Su Cho
{"title":"Commentary: Preoperative versus Intraoperative Tissue Diagnosis in Highly Suspicious Stage I Lung Cancer: Which Is the Superior Approach?","authors":"Jeong Su Cho","doi":"10.5090/jcs.24.074","DOIUrl":"10.5090/jcs.24.074","url":null,"abstract":"","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":" ","pages":"447-449"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Next-Generation Frozen Elephant Trunk Technique in the Era of Precision Medicine. 精准医疗时代的新一代冷冻象鼻技术。
Journal of Chest Surgery Pub Date : 2024-09-05 DOI: 10.5090/jcs.24.089
Suk-Won Song, Ha Lee, Myeong Su Kim, Randolph Hung Leung Wong, Jacky Yan Kit Ho, Wilson Y Szeto, Heinz Jakob
{"title":"Next-Generation Frozen Elephant Trunk Technique in the Era of Precision Medicine.","authors":"Suk-Won Song, Ha Lee, Myeong Su Kim, Randolph Hung Leung Wong, Jacky Yan Kit Ho, Wilson Y Szeto, Heinz Jakob","doi":"10.5090/jcs.24.089","DOIUrl":"10.5090/jcs.24.089","url":null,"abstract":"<p><p>The frozen elephant trunk (FET) technique can be applied to extensive aortic pathology, including lesions in the aortic arch and proximal descending thoracic aorta. FET is useful for tear-oriented surgery in dissections, managing malperfusion syndrome, and promoting positive aortic remodeling. Despite these benefits, complications such as distal stent-induced new entry and spinal cord ischemia can pose serious problems with the FET technique. To prevent these complications, careful sizing and planning of the FET are crucial. Additionally, since the FET technique involves total arch replacement, meticulous surgical skills are essential, particularly for young surgeons. In this article, we propose several techniques to simplify surgical procedures, which may lead to better outcomes for patients with extensive aortic pathology. In the era of precision medicine, the next-generation FET device could facilitate the treatment of complex aortic diseases through a patient-tailored approach.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":"57 5","pages":"419-429"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interfissural Fixation of the Right Middle Lobe after Video-Assisted Thoracic Surgery Right Upper Lobectomy: Bronchial Anatomical Changes and Efficacy in Preventing Torsion. 视频辅助胸腔手术右上肺叶切除术后的右中叶剪刀间固定术:支气管解剖学变化和预防扭转的效果。
Journal of Chest Surgery Pub Date : 2024-09-05 Epub Date: 2024-08-08 DOI: 10.5090/jcs.24.026
Dong Jae Han, You Jung Ok, Se Jin Oh, Jae-Sung Choi, Yong Won Seong, Hyeon Jong Moon
{"title":"Interfissural Fixation of the Right Middle Lobe after Video-Assisted Thoracic Surgery Right Upper Lobectomy: Bronchial Anatomical Changes and Efficacy in Preventing Torsion.","authors":"Dong Jae Han, You Jung Ok, Se Jin Oh, Jae-Sung Choi, Yong Won Seong, Hyeon Jong Moon","doi":"10.5090/jcs.24.026","DOIUrl":"10.5090/jcs.24.026","url":null,"abstract":"<p><strong>Background: </strong>Torsion of the right middle lobe following right upper lobectomy is a rare but potentially fatal complication. To prevent this, fixation of the right middle lobe has been suggested. This study was performed to examine the impact of right middle lobe fixation on postoperative outcomes and bronchial changes.</p><p><strong>Methods: </strong>We enrolled patients who underwent curative-intent video-assisted thoracic surgery (VATS) right upper lobectomy for lung cancer from 2019 to 2022. Participants were grouped based on whether they did or did not receive right middle lobe fixation. Bronchial angles were measured using preoperative and postoperative chest computed tomography images, and postoperative outcomes and bronchial changes were compared between the 2 groups.</p><p><strong>Results: </strong>The study included a total of 50 patients, with 17 (34%) undergoing right middle lobe fixation. All procedures were performed using VATS. No significant differences between groups were observed in preoperative characteristics or postoperative outcomes. After surgery, both groups exhibited a significant increase in the right bronchus intermedius angle and a significant decrease in the branch angle. The postoperative right bronchus intermedius angle was significantly larger in the group without right middle lobe fixation compared to the group with fixation (47.38°±10.98° vs. 39.41°±9.21°, p=0.014). Three cases of atelectasis occurred in the group that did not undergo fixation while no cases were observed in the fixation group; however, this difference was not statistically significant.</p><p><strong>Conclusion: </strong>Fixation of the right middle lobe reduced postoperative angulation of the right bronchus intermedius, which may help prevent postoperative atelectasis.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":" ","pages":"477-483"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Implications of Selective Dissection of Left Lower Paratracheal Lymph Nodes in Patients with Left-Sided Non-Small Cell Lung Cancer. 左侧非小细胞肺癌患者气管旁左下淋巴结选择性切除术的预后意义
Journal of Chest Surgery Pub Date : 2024-09-05 Epub Date: 2024-08-08 DOI: 10.5090/jcs.24.022
Hyo Kyen Park, Yelee Kwon, Geun Dong Lee, Sehoon Choi, Hyeong Ryul Kim, Yong-Hee Kim, Dong Kwan Kim, Seung-Il Park, Jae Kwang Yun
{"title":"Prognostic Implications of Selective Dissection of Left Lower Paratracheal Lymph Nodes in Patients with Left-Sided Non-Small Cell Lung Cancer.","authors":"Hyo Kyen Park, Yelee Kwon, Geun Dong Lee, Sehoon Choi, Hyeong Ryul Kim, Yong-Hee Kim, Dong Kwan Kim, Seung-Il Park, Jae Kwang Yun","doi":"10.5090/jcs.24.022","DOIUrl":"10.5090/jcs.24.022","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to examine the clinical implications of selective station 4L lymph node dissection (S4L-LND) on survival in non-small cell lung cancer (NSCLC) and to evaluate its potential advantages.</p><p><strong>Methods: </strong>We enrolled patients with primary left-sided NSCLC who underwent upfront video-assisted thoracoscopic surgery with R0 resection including lobectomy and segmentectomy, with or without S4L-LND, at our institution between January 2007 and December 2021. Following 1:1 propensity score matching (PSM), we compared overall survival (OS) and recurrence-free survival (RFS) between patients with and without S4L-LND.</p><p><strong>Results: </strong>The study included 2,601 patients, of whom 1,126 underwent S4L-LND and 1,475 did not. PSM yielded 1,036 patient pairs. Among those who underwent S4L-LND, 87 (7.7%) exhibited S4L-LN involvement. Neither OS (p=0.12) nor RFS (p=0.24) differed significantly between matched patients with and without S4L-LND. In patients with S4L-LN involvement, metastases were more common in the left upper lobe (LUL) than in the left lower lobe (LLL) (3.6% vs. 2.0%, p=0.061). Metastasis became significantly more frequent with more advanced clinical N (cN) stage (cN0, 2.3%; cN1, 5.8%; cN2, 32.6%; p<0.001). Multivariate logistic regression analysis revealed that cN stage and tumor location were independently associated with S4L-LN involvement (p<0.001 for both).</p><p><strong>Conclusion: </strong>OS and RFS did not differ significantly between matched patients with and without S4L-LND. Among participants with S4L-LN involvement, metastases occurred more frequently in the LUL than the LLL, and their incidence increased significantly with more advanced cN stage. Thus, patients with LUL or advanced cN lung cancers may benefit from S4L-LND.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":" ","pages":"467-476"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential Survival Benefit of Upfront Surgery for Lung Tumors Unconfirmed but Highly Suspicious for Stage I Lung Cancer. 对未经确诊但高度可疑的 I 期肺癌患者进行前期手术治疗的潜在生存益处。
Journal of Chest Surgery Pub Date : 2024-09-05 Epub Date: 2024-06-05 DOI: 10.5090/jcs.23.166
Murat Kara, Eren Erdogdu, Salih Duman, Gulnar Fatalizade, Berker Ozkan, Alper Toker
{"title":"Potential Survival Benefit of Upfront Surgery for Lung Tumors Unconfirmed but Highly Suspicious for Stage I Lung Cancer.","authors":"Murat Kara, Eren Erdogdu, Salih Duman, Gulnar Fatalizade, Berker Ozkan, Alper Toker","doi":"10.5090/jcs.23.166","DOIUrl":"10.5090/jcs.23.166","url":null,"abstract":"<p><strong>Background: </strong>Patients with early-stage lung tumors that are highly suspicious for malignancy typically undergo a preoperative diagnostic workup, primarily through bronchoscopy or transthoracic biopsy. Those without a preoperative diagnosis may alternatively be treated with upfront surgery, contingent upon the potential for intraoperative diagnosis. Previous studies have yielded conflicting results regarding the impact of upfront surgery on the survival of these patients. Our study aimed to elucidate the effect of upfront surgery on the survival outcomes of patients undergoing surgery for early-stage lung cancer without a preoperative diagnosis.</p><p><strong>Methods: </strong>We analyzed the survival rate of 158 consecutive patients who underwent pulmonary resection for stage I lung cancer, either with or without a preoperative diagnosis.</p><p><strong>Results: </strong>A total of 86 patients (54%) underwent upfront surgery. This approach positively impacted both disease-free survival (p=0.031) and overall survival (p=0.017). However, no significant differences were observed across subgroups based on sex, smoking status, forced expiratory volume in 1 second, histologic tumor size, or histologic subtype. Univariate analysis identified upfront surgery (p=0.020), age (p=0.002), maximum standardized uptake value (SUVmax) exceeding 7 (p=0.001), and histological tumor size greater than 20 mm (p=0.009) as independent predictors. However, multivariate analysis indicated that only SUVmax greater than 7 (p=0.011) was a significant predictor of unfavorable survival.</p><p><strong>Conclusion: </strong>Upfront surgery does not appear to confer a survival advantage in patients with stage I lung cancer undergoing surgical intervention.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":" ","pages":"440-446"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety of Perioperative Maintenance of Antiplatelet Agents in Elderly Patients Undergoing Lung Cancer Surgery. 肺癌手术老年患者围手术期维持使用抗血小板药物的安全性
Journal of Chest Surgery Pub Date : 2024-07-05 Epub Date: 2024-03-13 DOI: 10.5090/jcs.23.155
Hee Ju Hong, Ji Hyeon Park, Samina Park, In Kyu Park, Chang Hyun Kang, Young Tae Kim
{"title":"Safety of Perioperative Maintenance of Antiplatelet Agents in Elderly Patients Undergoing Lung Cancer Surgery.","authors":"Hee Ju Hong, Ji Hyeon Park, Samina Park, In Kyu Park, Chang Hyun Kang, Young Tae Kim","doi":"10.5090/jcs.23.155","DOIUrl":"10.5090/jcs.23.155","url":null,"abstract":"<p><strong>Background: </strong>The maintenance of antiplatelet therapy increases the risk of bleeding during lung cancer surgery. Conversely, the perioperative interruption of antiplatelet therapy may result in serious thrombotic complications. This study aimed to investigate the safety of continuing antiplatelet therapy in the context of lung cancer surgery.</p><p><strong>Methods: </strong>We retrospectively reviewed a cohort of 498 elderly patients who underwent surgery for lung cancer. These patients were categorized into 2 groups: group N, which did not receive antiplatelet therapy, and group A, which did. Group A was subsequently subdivided into group Am, where antiplatelet therapy was maintained, and group Ai, where antiplatelet therapy was interrupted. We compared the incidence of bleeding-related and thrombotic complications across the 3 groups.</p><p><strong>Results: </strong>There were 387 patients in group N and 101 patients in group A (Ai: 70, Am: 31). No significant differences were found in intraoperative blood loss, thoracotomy conversion rates, transfusion requirements, volume of chest tube drainage, or reoperation rates for bleeding control between groups N and A or between groups Am and Ai. The duration of hospital stay was longer for group A compared to group N (7 days vs. 6 days, p=0.005), but there was no significant difference between groups Ai and Am. The incidence of cardiovascular or cerebrovascular complications did not differ significantly between groups Ai and Am. However, group Ai included a severe case of in-hospital ST-elevation myocardial infarction.</p><p><strong>Conclusion: </strong>The maintenance of antiplatelet therapy was found to be safe in terms of perioperative bleeding and thrombotic complications in elderly lung cancer surgery patients.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":" ","pages":"342-350"},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11240096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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