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ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology最新文献

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Scaffold protein Scribble is a potent modulator of Sonic Hedgehog signaling 支架蛋白Scribble是Sonic Hedgehog信号的有效调节剂
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.283020
Jingwen Zhu, S. Ranjit, Yao Wang, F. Zindy, M. Roussel, J. Schuetz
{"title":"Scaffold protein Scribble is a potent modulator of Sonic Hedgehog signaling","authors":"Jingwen Zhu, S. Ranjit, Yao Wang, F. Zindy, M. Roussel, J. Schuetz","doi":"10.1124/jpet.122.283020","DOIUrl":"https://doi.org/10.1124/jpet.122.283020","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116628131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting mitochondrial protein NIX mediates resistance to sorafenib in hepatocellular carcinoma through autophagy 靶向线粒体蛋白NIX通过自噬介导肝癌对索拉非尼的耐药
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.144470
QiongRong Zeng, Ze‐feng Liu, Xianwen Guo, Wenjuan Wang, Xuelian Huang, Fujian Li, Guo Zhang
{"title":"Targeting mitochondrial protein NIX mediates resistance to sorafenib in hepatocellular carcinoma through autophagy","authors":"QiongRong Zeng, Ze‐feng Liu, Xianwen Guo, Wenjuan Wang, Xuelian Huang, Fujian Li, Guo Zhang","doi":"10.1124/jpet.122.144470","DOIUrl":"https://doi.org/10.1124/jpet.122.144470","url":null,"abstract":".","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125336413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural and Mechanistic Basis for Gbetagamma-mediated Activation of Phosphoinositide 3-kinase-gamma β - γ介导的磷酸肌肽3-激酶活化的结构和机制基础
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.242730
Chun-Liang Chen, S. Ravala, Y. Yen, T. Klose, Ramizah Syahirah, John J. G. Tesmer, Qing Deng
{"title":"Structural and Mechanistic Basis for Gbetagamma-mediated Activation of Phosphoinositide 3-kinase-gamma","authors":"Chun-Liang Chen, S. Ravala, Y. Yen, T. Klose, Ramizah Syahirah, John J. G. Tesmer, Qing Deng","doi":"10.1124/jpet.122.242730","DOIUrl":"https://doi.org/10.1124/jpet.122.242730","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123653412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanistic Investigation of a Combination of a Cell Cycle Inhibitor and an HDAC Inhibitor in Pancreatic Cancer Cells 细胞周期抑制剂和HDAC抑制剂联合作用胰腺癌细胞的机制研究
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.189660
Shraddha Bhutkar, Anjali Yadav, V. Dukhande
{"title":"Mechanistic Investigation of a Combination of a Cell Cycle Inhibitor and an HDAC Inhibitor in Pancreatic Cancer Cells","authors":"Shraddha Bhutkar, Anjali Yadav, V. Dukhande","doi":"10.1124/jpet.122.189660","DOIUrl":"https://doi.org/10.1124/jpet.122.189660","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125533295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Direct Targeting of Menin-MLL1 Interaction Inhibits Cancer Stem Cells to Inhibit Neuroblastoma Growth 直接靶向Menin-MLL1相互作用抑制肿瘤干细胞抑制神经母细胞瘤生长
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.205050
Rameswari Chilamakuri, Saurabh Agarwal
{"title":"Direct Targeting of Menin-MLL1 Interaction Inhibits Cancer Stem Cells to Inhibit Neuroblastoma Growth","authors":"Rameswari Chilamakuri, Saurabh Agarwal","doi":"10.1124/jpet.122.205050","DOIUrl":"https://doi.org/10.1124/jpet.122.205050","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121201595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recombinant miR-7-5p Effectively Inhibits NSCLC Cell Viability through Regulating Mitochondrial Function 重组miR-7-5p通过调节线粒体功能有效抑制非小细胞肺癌细胞活力
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.151360
Gavin M. Traber, Mei-Juan Tu, N. Batra, Colleen Yi, Aiming Yu
{"title":"Recombinant miR-7-5p Effectively Inhibits NSCLC Cell Viability through Regulating Mitochondrial Function","authors":"Gavin M. Traber, Mei-Juan Tu, N. Batra, Colleen Yi, Aiming Yu","doi":"10.1124/jpet.122.151360","DOIUrl":"https://doi.org/10.1124/jpet.122.151360","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122730090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategies to Circumvent Topoisomerase IIα Intron 19 Intronic Polyadenylation (IPA) in Acquired Etoposide Resistance Human Leukemia K562 Cells 获得性依托泊苷耐药人白血病K562细胞中规避拓扑异构酶i α内含子19内含子多腺苷化(IPA)的策略
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.207410
Xinyi Wang, Jessika Carvajal-Moreno, J. Yalowich, T. Elton
{"title":"Strategies to Circumvent Topoisomerase IIα Intron 19 Intronic Polyadenylation (IPA) in Acquired Etoposide Resistance Human Leukemia K562 Cells","authors":"Xinyi Wang, Jessika Carvajal-Moreno, J. Yalowich, T. Elton","doi":"10.1124/jpet.122.207410","DOIUrl":"https://doi.org/10.1124/jpet.122.207410","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125993900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis And Anticancer Properties of Polyrhodanine Copper Nanocomposites 聚罗丹宁铜纳米复合材料的合成及其抗癌性能
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.535680
S. Ghoshal, N. Spence, Moni Chauhan, Qiaxian R. Johnson, B. Chauhan
{"title":"Synthesis And Anticancer Properties of Polyrhodanine Copper Nanocomposites","authors":"S. Ghoshal, N. Spence, Moni Chauhan, Qiaxian R. Johnson, B. Chauhan","doi":"10.1124/jpet.122.535680","DOIUrl":"https://doi.org/10.1124/jpet.122.535680","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132511766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sanggenon G, a Diels-Alder Adduct Screened from Mori Cortex, Attenuated Irinotecan-induced Late-onset Diarrhea in Mice via a Dual Inhibition Mechanism 从森皮质中筛选的Diels-Alder加合物Sanggenon G通过双重抑制机制减轻伊立替康诱导的小鼠迟发性腹泻
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.227830
R. Yan, Panpan Wang, Zhiqiang Chen, Rongrong Wu, Yifei Jia
{"title":"Sanggenon G, a Diels-Alder Adduct Screened from Mori Cortex, Attenuated Irinotecan-induced Late-onset Diarrhea in Mice via a Dual Inhibition Mechanism","authors":"R. Yan, Panpan Wang, Zhiqiang Chen, Rongrong Wu, Yifei Jia","doi":"10.1124/jpet.122.227830","DOIUrl":"https://doi.org/10.1124/jpet.122.227830","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"52 3-4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121005976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic Rewiring and Mechanism of Action of an Antiepileptic Drug Repurposed for its Potential in Glioblastoma 一种抗癫痫药物在胶质母细胞瘤中的代谢重布线及其作用机制
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.291070
Anjali Yadav, Shraddha Bhutkar, V. Dukhande
{"title":"Metabolic Rewiring and Mechanism of Action of an Antiepileptic Drug Repurposed for its Potential in Glioblastoma","authors":"Anjali Yadav, Shraddha Bhutkar, V. Dukhande","doi":"10.1124/jpet.122.291070","DOIUrl":"https://doi.org/10.1124/jpet.122.291070","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121272632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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