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ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology最新文献

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MCL1 Small Molecule Inhibitor S63845 Synergizes with Cisplatin in Basal-like Triple Negative Breast Cancer MCL1小分子抑制剂S63845与顺铂协同治疗基底样三阴性乳腺癌
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.153220
Alexus Acton, W. Placzek
{"title":"MCL1 Small Molecule Inhibitor S63845 Synergizes with Cisplatin in Basal-like Triple Negative Breast Cancer","authors":"Alexus Acton, W. Placzek","doi":"10.1124/jpet.122.153220","DOIUrl":"https://doi.org/10.1124/jpet.122.153220","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124908664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sotorasib, a KRAS-G12C Inhibitor, Induces Chemoresistance by Activating Human Pregnane Xenobiotic Receptor KRAS-G12C抑制剂Sotorasib通过激活人妊娠异种受体诱导化疗耐药
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.233430
J. Salamat, Kodye L. Abbott, Elizabeth L. Ledbetter, Chuanling Xu, S. Pondugula
{"title":"Sotorasib, a KRAS-G12C Inhibitor, Induces Chemoresistance by Activating Human Pregnane Xenobiotic Receptor","authors":"J. Salamat, Kodye L. Abbott, Elizabeth L. Ledbetter, Chuanling Xu, S. Pondugula","doi":"10.1124/jpet.122.233430","DOIUrl":"https://doi.org/10.1124/jpet.122.233430","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124551306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipin-1 Silencing Alters the Phospholipid Profiles of Castration-Resistant Prostate Cancer Cells 脂素-1沉默改变去势抵抗前列腺癌细胞的磷脂谱
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.231370
Morgan C. Finnerty, B. Cummings
{"title":"Lipin-1 Silencing Alters the Phospholipid Profiles of Castration-Resistant Prostate Cancer Cells","authors":"Morgan C. Finnerty, B. Cummings","doi":"10.1124/jpet.122.231370","DOIUrl":"https://doi.org/10.1124/jpet.122.231370","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125987335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Anticancer Activity of Novel Norethindrone Analogs in Glioblastoma Cells 新型去甲thindrone类似物对胶质母细胞瘤细胞的抗癌活性评价
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.561410
Katelyn A. Harris, Courtney A. Hollenbacher, Eric T. Doyle, Samantha T. Szoradi, Nicholas A. Reid, Laura R. Inbody, Richard W Dudley, Ryan A. Schneider
{"title":"Evaluating the Anticancer Activity of Novel Norethindrone Analogs in Glioblastoma Cells","authors":"Katelyn A. Harris, Courtney A. Hollenbacher, Eric T. Doyle, Samantha T. Szoradi, Nicholas A. Reid, Laura R. Inbody, Richard W Dudley, Ryan A. Schneider","doi":"10.1124/jpet.122.561410","DOIUrl":"https://doi.org/10.1124/jpet.122.561410","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134107596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HUNK regulation of IL-4 promotes polarization of tumor-associated macrophages in TNBC tumor microenvironment HUNK调节IL-4促进TNBC肿瘤微环境中肿瘤相关巨噬细胞的极化
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.167200
Nicole Ramos Solis, Elizabeth S. Yeh, M. Kaplan, Anthony Cannon
{"title":"HUNK regulation of IL-4 promotes polarization of tumor-associated macrophages in TNBC tumor microenvironment","authors":"Nicole Ramos Solis, Elizabeth S. Yeh, M. Kaplan, Anthony Cannon","doi":"10.1124/jpet.122.167200","DOIUrl":"https://doi.org/10.1124/jpet.122.167200","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"207 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133818483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptive Changes in Tumor Cells in Response to Reductive Stress 肿瘤细胞对还原性应激反应的适应性变化
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.206390
Leilei Zhang, Jie Zhang, Zhiwei Ye, A. Muhammad, J. Culpepper, D. Townsend, K. Tew
{"title":"Adaptive Changes in Tumor Cells in Response to Reductive Stress","authors":"Leilei Zhang, Jie Zhang, Zhiwei Ye, A. Muhammad, J. Culpepper, D. Townsend, K. Tew","doi":"10.1124/jpet.122.206390","DOIUrl":"https://doi.org/10.1124/jpet.122.206390","url":null,"abstract":"Abstract","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121196942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Significance of topical chemotherapy application on human and murine skin 人、鼠皮肤局部化疗应用的意义
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.235940
A. Thyagarajan, Krishna Awasthi, C. Rapp, K. Miller, R. Johnson, Yanfang Chen, J. Travers, R. Sahu
{"title":"Significance of topical chemotherapy application on human and murine skin","authors":"A. Thyagarajan, Krishna Awasthi, C. Rapp, K. Miller, R. Johnson, Yanfang Chen, J. Travers, R. Sahu","doi":"10.1124/jpet.122.235940","DOIUrl":"https://doi.org/10.1124/jpet.122.235940","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"201 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123561425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Defining the Role of Mitochondrial Dynamics in Regulating PDAC Cell Sensitivity to KRAS and ERK Inhibition 确定线粒体动力学在调节PDAC细胞对KRAS和ERK抑制的敏感性中的作用
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.269600
Amber Amparo, Kristina Drizyte-Miller, Claire E. Gates, A. Cox, Kirsten L. Bryant, C. Der
{"title":"Defining the Role of Mitochondrial Dynamics in Regulating PDAC Cell Sensitivity to KRAS and ERK Inhibition","authors":"Amber Amparo, Kristina Drizyte-Miller, Claire E. Gates, A. Cox, Kirsten L. Bryant, C. Der","doi":"10.1124/jpet.122.269600","DOIUrl":"https://doi.org/10.1124/jpet.122.269600","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123805971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the DNA Methylation Profile of Childhood Solid Tumors to Identify Novel Therapeutically Targeted Sites 检查儿童实体瘤的DNA甲基化谱以确定新的治疗靶点
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.535980
Sarah A. Albasha, Manar Z. Almotawa, Abdulmonem A. Alsaleh, Noura N. Alibrahim, Mariam K. Alamoudi, Zahiah F. Al Mohsen, Yahya Aldawood, Hayyan A. Al-Taweil, Fatimah J. Al Shaikh, Jenan A Almatouq
{"title":"Examining the DNA Methylation Profile of Childhood Solid Tumors to Identify Novel Therapeutically Targeted Sites","authors":"Sarah A. Albasha, Manar Z. Almotawa, Abdulmonem A. Alsaleh, Noura N. Alibrahim, Mariam K. Alamoudi, Zahiah F. Al Mohsen, Yahya Aldawood, Hayyan A. Al-Taweil, Fatimah J. Al Shaikh, Jenan A Almatouq","doi":"10.1124/jpet.122.535980","DOIUrl":"https://doi.org/10.1124/jpet.122.535980","url":null,"abstract":"","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123836164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Direct Targeting of the Cell cycle RegulatorWEE1is a Novel Therapeutic Approach for Neuroblastoma 直接靶向细胞周期调节因子wee1是治疗神经母细胞瘤的新途径
ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.283600
P. Suri, Rameswari Chilamakuri, Saurabh Agarwal
{"title":"Direct Targeting of the Cell cycle RegulatorWEE1is a Novel Therapeutic Approach for Neuroblastoma","authors":"P. Suri, Rameswari Chilamakuri, Saurabh Agarwal","doi":"10.1124/jpet.122.283600","DOIUrl":"https://doi.org/10.1124/jpet.122.283600","url":null,"abstract":"ID 28360","PeriodicalId":344837,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cancer Pharmacology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125457586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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