Open Respiratory Archives最新文献

{"title":"Long-Term Patient Symptoms and Quality of Life in Adults After COVID-19: A Real Life Study","authors":"Oscar Perez ,&nbsp;Miguel Santibañez ,&nbsp;Laura Rasines ,&nbsp;Jose Maria Castillo ,&nbsp;Adrian Hugo Aginagalde-Llorente","doi":"10.1016/j.opresp.2024.100336","DOIUrl":"10.1016/j.opresp.2024.100336","url":null,"abstract":"<div><h3>Objective</h3><p>To characterize long-term patient-reported symptoms and quality of life, in adults after COVID-19.</p></div><div><h3>Material and methods</h3><p>Cross-sectional study in Cantabria (Northern Spain) including adults with PCR-confirmed SARS-CoV-2 infection (<em>n</em> <!-->=<!--> <!-->694) with a time period between 4.7 and 24 month post-SARS-CoV-2 diagnosis, and their close contacts (<em>n</em> <!-->=<!--> <!-->663) (PCR negative and without suspected infection) obtained from simple random sampling of a total of 47,773 cases and 94,301 close contacts. The ISARIC survey was used as screening tool with self-reported “non-feeling fully recovery (NFFR)” defined as primary outcome.</p></div><div><h3>Results</h3><p>16.57% (<em>n</em> <!-->=<!--> <!-->115/694) reported NFFR. Most prevalent symptoms were in order of frequency: Fatigue (54.8%); Loss of smell (40.9%); Problems speaking or communicating (29.6%); Loss of taste (28.7%); Confusion/lack of concentration (27.8%); Persistent muscle pain (24.3%) and Shortness of breath/breathlessness (23.5%). When comparing the three ordinal groups (Close contacts, COVID-19 feeling recovered, and COVID-19 NFFR) the prevalence of these symptoms was increasingly higher among each ordinal group (<em>p</em> <!-->&lt;<!--> <!-->0.001). Female gender was significantly associated with NFFR: (adjusted odds ratio (aOR)<!--> <!-->=<!--> <!-->1.56); as well as older age: aOR per 10 year increment<!--> <!-->=<!--> <!-->1.15. Lastly, they scored on average 9.63 points less in Euroquol.</p></div><div><h3>Conclusions</h3><p>More than 15% of patients in our real-life population-based study, reported NFFR, being female sex and older age independent predictors of this condition. Most symptoms in these patients were in accordance with WHO definition of post COVID-19 condition in adults, and were less prevalent in COVID-19 feeling recovered and close contact respectively, with a statistically significant dose-response pattern, and with a large decrease in quality of life according to Euroquol.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100336"},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000390/pdfft?md5=ffac87a94aba520d23ebc6c5e97620c6&pid=1-s2.0-S2659663624000390-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141134495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Treatment Scenarios for Patients With Severe Asthma and Chronic Rhinosinusitis With Nasal Polyps. A Proposal From GEMA-POLINA Task Force","authors":"Vicente Plaza ,&nbsp;Christian Calvo-Henríquez ,&nbsp;Marina Blanco-Aparicio ,&nbsp;Carlos Colás ,&nbsp;Jorge del Estal ,&nbsp;Noé Garín ,&nbsp;Ruperto González-Pérez ,&nbsp;Juan Maza-Solano ,&nbsp;José Gregorio Soto ,&nbsp;Isam Alobid","doi":"10.1016/j.opresp.2024.100337","DOIUrl":"10.1016/j.opresp.2024.100337","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100337"},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000407/pdfft?md5=605bc09b8be07b0a55c322b0a12a8cb8&pid=1-s2.0-S2659663624000407-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141130685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Flow Oxygen: Respiratory Mechanics in Lung Alveoli of Patients After Acute Respiratory Failure","authors":"Alba Naya Prieto ,&nbsp;Carlos López Chang ,&nbsp;María del Pilar Carballosa de Miguel ,&nbsp;Miren Itziar Fernández Ormaechea ,&nbsp;María de los Ángeles Zambrano Chacón ,&nbsp;Luis Jiménez Hiscock ,&nbsp;Germán Peces-Barba Romero ,&nbsp;María Jesús Rodríguez Nieto ,&nbsp;Sarah Beatriz Heili Frades","doi":"10.1016/j.opresp.2024.100335","DOIUrl":"10.1016/j.opresp.2024.100335","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100335"},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000389/pdfft?md5=215aad90b6fa2072c664a30f7a23b912&pid=1-s2.0-S2659663624000389-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141139628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influencia de las guías de práctica clínica en el diagnóstico y tratamiento de la fibrosis pulmonar idiopática. Datos del Registro de la Sociedad Española de Neumología y Cirugía Torácica","authors":"Myriam Aburto ,&nbsp;José Antonio Rodríguez-Portal ,&nbsp;Estrella Fernandez-Fabrellas ,&nbsp;Raquel García Sevila ,&nbsp;Susana Herrera Lara ,&nbsp;Elena Bollo de Miguel ,&nbsp;José María González Ruiz ,&nbsp;María Molina-Molina ,&nbsp;Belén Safont Muñoz ,&nbsp;Raul Godoy Mayoral ,&nbsp;Ana Dolores Romero Ortiz ,&nbsp;María José Soler Sempere ,&nbsp;Diego Castillo Villegas ,&nbsp;Javier Gaudó Navarro ,&nbsp;Laura Tomás López ,&nbsp;Belén Nuñez Sanchez ,&nbsp;Zulema Palacios Hidalgo ,&nbsp;Jacobo Sellares Torres ,&nbsp;Lirios Sacristán Bou ,&nbsp;María Asunción Nieto Barbero ,&nbsp;Claudia Valenzuela","doi":"10.1016/j.opresp.2024.100334","DOIUrl":"10.1016/j.opresp.2024.100334","url":null,"abstract":"<div><h3>Objective</h3><p>The objective of the study was to analyze the diagnostic process and the time until the start of treatment of patients with idiopathic pulmonary fibrosis in relation to the publication of successive clinical practice guide.</p></div><div><h3>Material and methods</h3><p>Multicenter, observational, ambispective study, in which patients includes in the idiopathic pulmonary fibrosis registry of the Spanish Society of Pulmonologist and Thoracic Surgery were analyzed. An electronic data collection notebook was enabled on the society's website. Sociodemographic and clinical variables were collected at diagnosis and follow-up of the patients.</p></div><div><h3>Results</h3><p>From January 2012 to december 2019, 1064 patients were included in the registry, with 929 finally analyzed. The diagnosis process varied depending on the year in which it was performed, and the radiological pattern observed in the high-resolution computed tomography. Up to 26.3% of the cases (244) were diagnosed with chest high-resolution computed tomography and clinical evaluation. Surgical biopsy was used up to 50.2% of cases diagnosed before 2011, while it has been used in 14.2% since 2018. The median time from the onset of symptoms to diagnosis was 360 days (IQR 120-720), taking more than 2 years in the 21.0% of patients. A percentage of 79.4 of patients received antifibrotic treatment. The average time from diagnosis to the antifibrotic treatment has been 309<!--> <!-->±<!--> <!-->596.5 days, with a median of 49 (IQR 0-307).</p></div><div><h3>Conclusions</h3><p>The diagnostic process, including the time until diagnosis and the type of test used, has changed from 2011 to 2019, probably due to advances in clinical research and the publication of diagnostic-therapeutic consensus guidelines.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100334"},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000377/pdfft?md5=3830c625fed73c227b9b6ede3894cb8e&pid=1-s2.0-S2659663624000377-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141031678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacto de la telemonitorización como sistema para una adecuada titulación y adaptación de la CPAP domiciliaria en la apnea obstructiva del sueño (proyecto T-CPAP)","authors":"María Teresa Ramírez Prieto,&nbsp;M.a Vaneas Lores Gutiérrez,&nbsp;Raul Moreno Zabaleta,&nbsp;Rocío Rodríguez Pérez","doi":"10.1016/j.opresp.2024.100332","DOIUrl":"10.1016/j.opresp.2024.100332","url":null,"abstract":"<div><h3>Introduction</h3><p>Continuous Positive Airway Pressure (CPAP) constitutes the most effective treatment for Obstructive Sleep Apnea (OSA). Automatic titration systems (ATS) are predominantly used to achieve adaptation to the equipment. Home CPAP devices allow telemonitoring (TM) of the same parameters as those provided by ATS but with access to continuous usage data. Under this premise, we conducted a study on the potential validity of TM for home CPAP devices as a titration system, its direct impact on proper adaptation (AD) to the equipment, and secondarily on the healthcare resources employed to achieve it.</p></div><div><h3>Material and methods</h3><p>An observational study involving 318 patients with OSA who were titrated using TM to achieve AD to CPAP. Patients with OSA were consecutively recruited and evaluated at 1, 3, and 6 months after initiating treatment. Results were compared with a historical group of 307 patients with OSA who achieved AD to CPAP using ATS. Additionally, we assessed the impact on required healthcare resources.</p></div><div><h3>Results</h3><p>Patients with OSA who initiated CPAP treatment with TM over the first six months showed a similar AD rate compared to the historical group titrated using ATS, with lower resource usage in the TM group.</p></div><div><h3>Conclusion</h3><p>Data provided by TM of home CPAP devices allow for titration and achieving similar AD as with ATS in non-complex patients.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 ","pages":"Article 100332"},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000353/pdfft?md5=c001b26994f59ef46a186a6b0fa06801&pid=1-s2.0-S2659663624000353-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141035367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in the Implementation of the Spanish Consensus on the Reduction of Oral Corticosteroids: Insights From the Medical Community","authors":"Javier Dominguez-Ortega ,&nbsp;Xavier Muñoz-Gall ,&nbsp;Julio Delgado-Romero ,&nbsp;Francisco Casas-Maldonado ,&nbsp;Marina Blanco-Aparicio","doi":"10.1016/j.opresp.2024.100331","DOIUrl":"10.1016/j.opresp.2024.100331","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100331"},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000341/pdfft?md5=9e63cafc19aa117ceb3a4a2787cca217&pid=1-s2.0-S2659663624000341-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141051194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avances y desafíos en el control de la tuberculosis multirresistente (TB-MDR)","authors":"Eva Tabernero Huguet","doi":"10.1016/j.opresp.2024.100333","DOIUrl":"10.1016/j.opresp.2024.100333","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100333"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000365/pdfft?md5=fb2a097b60061ff6e683dd5e48c684a7&pid=1-s2.0-S2659663624000365-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141028055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supraglottic Stenosis After Caustic Ingestion","authors":"Sonia Salinas Castillo,&nbsp;Cristina López García-Gallo,&nbsp;Carlos Almonacid Sánchez","doi":"10.1016/j.opresp.2024.100328","DOIUrl":"10.1016/j.opresp.2024.100328","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100328"},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000316/pdfft?md5=86d8bdf5bdb2f69af65770a84a710d9e&pid=1-s2.0-S2659663624000316-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140783327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary Alveolar Proteinosis With Atypical Presentation Mimicking Acute Alveolar Sarcoidosis: A Challenging Diagnosis","authors":"Anna Michela Gaeta ,&nbsp;Adrián Nogales Moro ,&nbsp;Dita Kopecna ,&nbsp;Diego Tomás Vázquez Guile ,&nbsp;Mario Virgilio Di Campli ,&nbsp;Manuel Martínez Pérez","doi":"10.1016/j.opresp.2024.100330","DOIUrl":"10.1016/j.opresp.2024.100330","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100330"},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S265966362400033X/pdfft?md5=a2240cef6eb7bda22cc624f7458ea733&pid=1-s2.0-S265966362400033X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140771213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study on the Psychological Profile and Coping With the Disease in Patients With Lymphangioleiomyomatosis","authors":"David Rudilla ,&nbsp;María Molina ,&nbsp;Claudia Valenzuela ,&nbsp;Álvaro Casanova ,&nbsp;Julio Ancochea","doi":"10.1016/j.opresp.2024.100327","DOIUrl":"10.1016/j.opresp.2024.100327","url":null,"abstract":"<div><h3>Introduction</h3><p>Lymphangioleiomyomatosis (LAM) is a rare disease that affects women almost exclusively. We aimed to determine the psychological profile in patients with LAM, and their potential association with sociodemographic and clinical features, and to know their role in coping with the disease.</p></div><div><h3>Material and methods</h3><p>Cross-sectional and descriptive study in collaboration with the Spanish Association of LAM (AELAM). The variables measured were: socio-demographic, psychological (anxiety, depression, demoralization, spirituality, resilience, social support), clinical (treatment) and health-related quality of life.</p></div><div><h3>Results</h3><p>We studied 87 LAM patients, with a mean (SD) age of 47.7 (7.7) years, and time since diagnose was 10.1 (5.4) years. 75.9% of patients were receiving sirolimus or everolimus, and oxygen therapy was required in 34.5% of patients. Anxiety was found in 46% of patients, depression in 55%, while only 2% presented demoralization and 14% deficit in spirituality. Social support and resilience were adequate. The “non-severe” group (without oxygen therapy) presented worse results in anxiety. A structural equation model to explore association between variables, showed very adequate fit indices: <em>χ</em>²(14)<!--> <!-->=<!--> <!-->29.743 (<em>p</em> <!-->=<!--> <!-->.074); CFI<!--> <!-->=<!--> <!-->.983; TLI<!--> <!-->=<!--> <!-->.967; SRMR<!--> <!-->=<!--> <!-->.058; RMSEA<!--> <!-->=<!--> <!-->.075[.000–.128]. The model identifies resilience, spirituality and social support as “protective factors” from anxiety, depression, and demoralization.</p></div><div><h3>Conclusions</h3><p>This study performed on a large series of women with LAM describes their psychological profile, in addition to showing how they cope with the disease. We have found that other psychological constructs, such as perceived social support and resilience, are protective factors. Early psychological evaluation and intervention is necessary to reduce comorbidities and prevent mental health problems in women with LAM.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100327"},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000304/pdfft?md5=3b4fe2d15bac39598d7ba873943d58ba&pid=1-s2.0-S2659663624000304-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140781788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}