Open Respiratory Archives最新文献

{"title":"Patients’ Beliefs About Medicines and Adherence to Inhalers","authors":"Eduardo Garcia-Pachon , Justo Grau-Delgado , Carlos Baeza-Martínez , Lucía Zamora-Molina , Marta Galán-Negrillo , Marina Beléndez-Vázquez","doi":"10.1016/j.opresp.2024.100322","DOIUrl":"https://doi.org/10.1016/j.opresp.2024.100322","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100322"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000250/pdfft?md5=ddf8096f371c65b3109606e354a3eb9a&pid=1-s2.0-S2659663624000250-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140638792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential Effects on Elderly People From Nirsevimab Use in Infants","authors":"Iván Sanz-Muñoz ,&nbsp;Javier Castrodeza-Sanz ,&nbsp;José M. Eiros","doi":"10.1016/j.opresp.2024.100320","DOIUrl":"10.1016/j.opresp.2024.100320","url":null,"abstract":"<div><p>Nirsevimab therapy has the potential to revolutionize infant respiratory syncytial virus (RSV) prophylaxis. But other populations suffering RSV, such the elderly or those over 60, may also be protected by using this novel antibody in the infant group. It is true that some studies link the use of nirsevimab to a reduction in the virus's ability to spread by lowering the viral load in infants as a result of the drug's long half-life. However, this protective effect may not be very significant because RSV transmission in the elderly typically comes from other elderly people or from school-aged children. Furthermore, RSV may be transmitted at any time of the year and not just during the period of nirsevimab protection due to its existence in human reservoirs. The reasons made here show that, even though nirsevimab treatment in infants may protect the elderly, this benefit would be limited and testimonial. Therefore, immunizing the elderly with currently licensed and developing vaccines should be a priority.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100320"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000237/pdfft?md5=f4fcec8f7471df144b7c9c1558b6fc33&pid=1-s2.0-S2659663624000237-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140270988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Encuesta sobre la actividad de los laboratorios de función pulmonar. Efectos durante la pandemia por SARS-CoV-2","authors":"Laura Vigil Giménez ,&nbsp;Juana Martínez Llorens ,&nbsp;Karina Portillo Carroz ,&nbsp;Rocío García García ,&nbsp;Francisco Ortega Ruiz ,&nbsp;Luis Puente Maestu ,&nbsp;en representación del Grupo de Trabajo","doi":"10.1016/j.opresp.2024.100315","DOIUrl":"10.1016/j.opresp.2024.100315","url":null,"abstract":"<div><h3>Introduction</h3><p>Following the SARS-CoV-2 pandemic in March 2020, pulmonary function testing (PFT) laboratories underwent a transformation, with a reduction in the number of tests or closure in some cases. The aim of this work was to know the activity of PFT in Spain and the modification of this activity due to the pandemic.</p></div><div><h3>Material and methods</h3><p>A protocolised survey was carried out to members of the PFT laboratories through the Spanish Society of Pneumology and Thoracic Surgery (SEPAR).</p></div><div><h3>Results</h3><p>Thirty-nine hospitals in Spain responded. The pulmonary function tests most frequently performed in the PFT laboratories were forced spirometry with bronchodilator test (100%), body plethysmography (97.4%), CO transfer capacity (97.4%), respiratory muscle strength measured in the mouth (97.4%), 6-minute walking test (94.7%), measurement of exhaled fraction of nitric oxide (92.3%) and incremental exercise test (71.8%).</p><p>The pandemic led to a significant decrease in the number of tests (35.4%) during 2020 with subsequent recovery in 2021, without reaching pre-pandemic values.</p><p>The most important changes were increased examination times, working with personal protective equipment and ventilation of the rooms. The performance of the nasopharyngeal swab for SARS-CoV2 testing prior to the tests was not homogeneous in the PFT laboratories.</p></div><div><h3>Conclusions</h3><p>Most hospitals are sufficiently equipped to perform the most common pulmonary function tests. The pandemic resulted in a loss of activity in all hospitals.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100315"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000183/pdfft?md5=b4154b74ab3598cfc83bded8a4af1865&pid=1-s2.0-S2659663624000183-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140281835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Natural History of Severe Chronic Obstructive Pulmonary Disease: The SPOCCAT Study Protocol","authors":"Jessica González ,&nbsp;Dan Sánchez ,&nbsp;Daniel Ross-Monserrate ,&nbsp;Elena Miguel ,&nbsp;Marc Miravitlles ,&nbsp;Roser Costa ,&nbsp;on behalf of the SPOCCAT study","doi":"10.1016/j.opresp.2024.100321","DOIUrl":"https://doi.org/10.1016/j.opresp.2024.100321","url":null,"abstract":"<div><h3>Introduction</h3><p>Patients with severe chronic obstructive pulmonary disease (COPD) are often underrepresented in cohorts, creating uncertainty about the natural history and prognostic factors of this subgroup. Our goal was to describe the SPOCCAT (Severe COPD: Prospective Observational study of COPD in Catalonia) study protocol.</p></div><div><h3>Material and methods</h3><p>SPOCCAT is a non-interventional, multicenter, prospective cohort study of patients with severe COPD (FEV₁% predicted<!--> <!-->&lt;<!--> <!-->50%). The study aims to: (1) establish a five-year prospective cohort; (2) identify demographic and clinical characteristics; (3) describe treatment patterns; (4) better understand the natural history of severe COPD, including lung function decline, exacerbation rates, and mortality; and (5) identify prognostic factors for poor outcomes.</p><p>Recruitment began in January 2024, and the cohort will be followed for a minimum of five years (or until death or lung transplant) with follow-up visits every 12 months. Baseline data include demographics, laboratory analyses, comorbidities, lung function, respiratory symptoms, respiratory disease exacerbations and etiology, quality of life, physical activity, chest computed tomography, and treatment. Annual follow-up visits will assess changes in treatment, exacerbation frequency and severity, microbiological outcomes, complementary tests, and mortality. Participation requires written informed consent from all patients, with data collected in an anonymized electronic Case Report Form.</p></div><div><h3>Results</h3><p>The results of the SPOCCAT study will provide relevant information about the characteristics, treatment, and prognostic factors of severe COPD.</p></div><div><h3>Conclusions</h3><p>SPOCCAT has the potential to enhance understanding of severe COPD, exploring innovative aspects and establishing a robust research framework for future COPD-related projects.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100321"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000249/pdfft?md5=72ad9e7d25582f67c17023fc3c46d0e8&pid=1-s2.0-S2659663624000249-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140638791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psicosis inducida por isoniazida: a propósito de un caso","authors":"Sara Calero Pardo ,&nbsp;Beatriz Raboso Moreno ,&nbsp;Araceli Abad Fernández","doi":"10.1016/j.opresp.2024.100314","DOIUrl":"10.1016/j.opresp.2024.100314","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100314"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000171/pdfft?md5=913e75c0c672d19136278712fec44a39&pid=1-s2.0-S2659663624000171-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140271292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics of Bronchiectasis due to Transplant-Related Immunosuppression","authors":"David Rodríguez-Plaza ,&nbsp;Ane Martínez-De las Fuentes ,&nbsp;Javier Burgos ,&nbsp;Núria Sabé ,&nbsp;Salud Santos ,&nbsp;Guillermo Suárez-Cuartín","doi":"10.1016/j.opresp.2024.100319","DOIUrl":"https://doi.org/10.1016/j.opresp.2024.100319","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100319"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000225/pdfft?md5=b0ed8b2c2ed15e154e62c946582fd420&pid=1-s2.0-S2659663624000225-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140620879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-flow Nasal Oxygen Therapy Yields a Favorable Outcome in Patient Presenting With Kussmaul Breathing","authors":"René Agustín Flores-Franco ,&nbsp;Carlos Mauricio González-Ponce ,&nbsp;Victor Irigoyen-Monroy","doi":"10.1016/j.opresp.2024.100316","DOIUrl":"10.1016/j.opresp.2024.100316","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100316"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000195/pdfft?md5=0bf8169b18e329e1a9c82ace45f00a0b&pid=1-s2.0-S2659663624000195-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140278547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence Applied to Forced Spirometry in Primary Care","authors":"Rosaly Moreno Mendez ,&nbsp;Antonio Marín ,&nbsp;José Ramon Ferrando ,&nbsp;Giuliana Rissi Castro ,&nbsp;Sonia Cepeda Madrigal ,&nbsp;Gabriela Agostini ,&nbsp;Pablo Catalan Serra","doi":"10.1016/j.opresp.2024.100313","DOIUrl":"10.1016/j.opresp.2024.100313","url":null,"abstract":"<div><h3>Introduction</h3><p>This study aims to create an artificial intelligence (AI) based machine learning (ML) model capable of predicting a spirometric obstructive pattern using variables with the highest predictive power derived from an active case-finding program for COPD in primary care.</p></div><div><h3>Material and methods</h3><p>A total of 1190 smokers, aged 30–80 years old with no prior history of respiratory disease, underwent spirometry with bronchodilation. The sample was analyzed using AI tools. Based on an exploratory data analysis (EDA), independent variables (according to mutual information analysis) were trained using a gradient boosting algorithm (GBT) and validated through cross-validation.</p></div><div><h3>Results</h3><p>With an area under the curve close to unity, the model predicted a spirometric obstructive pattern using variables with the highest predictive power: FEV1_theoretical_pre values. Sensitivity: 93%. Positive predictive value: 94%. Specificity: 97%. Negative predictive value: 96%. Accuracy: 95%. Precision: 94%.</p></div><div><h3>Conclusion</h3><p>An ML model can predict the presence of an obstructive pattern in spirometry in a primary care smoking population with no prior diagnosis of respiratory disease using the FEV1_theoretical_pre values with an accuracy and precision exceeding 90%. Further studies including clinical data and strategies for integrating AI into clinical workflow are needed.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 ","pages":"Article 100313"},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S265966362400016X/pdfft?md5=48496b70dbeeabf981ea1982451c3307&pid=1-s2.0-S265966362400016X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140082796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Eosinophilic Asthma and Severe Mixed Polyneuropathy: A Case of Eosinophilic Granulomatous Vasculitis With Polyangiitis and New Therapeutic Perspectives","authors":"María del Carmen Lorenzo Martínez ,&nbsp;Ángela Hidalgo Herranz ,&nbsp;Ana María Ochoa Ruiz ,&nbsp;Bárbara Gutierrez Ruano ,&nbsp;Raúl Ruiz Esteban ,&nbsp;Sergio Campos Téllez ,&nbsp;José Javier Jareño Esteban","doi":"10.1016/j.opresp.2024.100312","DOIUrl":"10.1016/j.opresp.2024.100312","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100312"},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000158/pdfft?md5=fcad89ecb3fa9b4780bd94a46d049e7f&pid=1-s2.0-S2659663624000158-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140088887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endobronchial Fibroanthracosis Associated With Mycobacterium Chimaera Infection: An Exceptional Case","authors":"Fernando Garcia-Prieto ,&nbsp;Adriana Rodríguez Perojo ,&nbsp;María Teresa Río Ramírez","doi":"10.1016/j.opresp.2024.100309","DOIUrl":"https://doi.org/10.1016/j.opresp.2024.100309","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100309"},"PeriodicalIF":0.0,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000122/pdfft?md5=9a67576300a963818ec99781814317e0&pid=1-s2.0-S2659663624000122-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140162989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}