Open Respiratory Archives最新文献

{"title":"Avances y desafíos en el control de la tuberculosis multirresistente (TB-MDR)","authors":"Eva Tabernero Huguet","doi":"10.1016/j.opresp.2024.100333","DOIUrl":"10.1016/j.opresp.2024.100333","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100333"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000365/pdfft?md5=fb2a097b60061ff6e683dd5e48c684a7&pid=1-s2.0-S2659663624000365-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141028055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supraglottic Stenosis After Caustic Ingestion","authors":"Sonia Salinas Castillo, Cristina López García-Gallo, Carlos Almonacid Sánchez","doi":"10.1016/j.opresp.2024.100328","DOIUrl":"10.1016/j.opresp.2024.100328","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100328"},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000316/pdfft?md5=86d8bdf5bdb2f69af65770a84a710d9e&pid=1-s2.0-S2659663624000316-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140783327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary Alveolar Proteinosis With Atypical Presentation Mimicking Acute Alveolar Sarcoidosis: A Challenging Diagnosis","authors":"Anna Michela Gaeta , Adrián Nogales Moro , Dita Kopecna , Diego Tomás Vázquez Guile , Mario Virgilio Di Campli , Manuel Martínez Pérez","doi":"10.1016/j.opresp.2024.100330","DOIUrl":"10.1016/j.opresp.2024.100330","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100330"},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S265966362400033X/pdfft?md5=a2240cef6eb7bda22cc624f7458ea733&pid=1-s2.0-S265966362400033X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140771213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study on the Psychological Profile and Coping With the Disease in Patients With Lymphangioleiomyomatosis","authors":"David Rudilla ,&nbsp;María Molina ,&nbsp;Claudia Valenzuela ,&nbsp;Álvaro Casanova ,&nbsp;Julio Ancochea","doi":"10.1016/j.opresp.2024.100327","DOIUrl":"10.1016/j.opresp.2024.100327","url":null,"abstract":"<div><h3>Introduction</h3><p>Lymphangioleiomyomatosis (LAM) is a rare disease that affects women almost exclusively. We aimed to determine the psychological profile in patients with LAM, and their potential association with sociodemographic and clinical features, and to know their role in coping with the disease.</p></div><div><h3>Material and methods</h3><p>Cross-sectional and descriptive study in collaboration with the Spanish Association of LAM (AELAM). The variables measured were: socio-demographic, psychological (anxiety, depression, demoralization, spirituality, resilience, social support), clinical (treatment) and health-related quality of life.</p></div><div><h3>Results</h3><p>We studied 87 LAM patients, with a mean (SD) age of 47.7 (7.7) years, and time since diagnose was 10.1 (5.4) years. 75.9% of patients were receiving sirolimus or everolimus, and oxygen therapy was required in 34.5% of patients. Anxiety was found in 46% of patients, depression in 55%, while only 2% presented demoralization and 14% deficit in spirituality. Social support and resilience were adequate. The “non-severe” group (without oxygen therapy) presented worse results in anxiety. A structural equation model to explore association between variables, showed very adequate fit indices: <em>χ</em>²(14)<!--> <!-->=<!--> <!-->29.743 (<em>p</em> <!-->=<!--> <!-->.074); CFI<!--> <!-->=<!--> <!-->.983; TLI<!--> <!-->=<!--> <!-->.967; SRMR<!--> <!-->=<!--> <!-->.058; RMSEA<!--> <!-->=<!--> <!-->.075[.000–.128]. The model identifies resilience, spirituality and social support as “protective factors” from anxiety, depression, and demoralization.</p></div><div><h3>Conclusions</h3><p>This study performed on a large series of women with LAM describes their psychological profile, in addition to showing how they cope with the disease. We have found that other psychological constructs, such as perceived social support and resilience, are protective factors. Early psychological evaluation and intervention is necessary to reduce comorbidities and prevent mental health problems in women with LAM.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100327"},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000304/pdfft?md5=3b4fe2d15bac39598d7ba873943d58ba&pid=1-s2.0-S2659663624000304-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140781788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combining Spirometry and the ARISCAT Respiratory Risk Assessment Can Improve Postoperative Outcomes and Reduce Mortality Risk in Mexico","authors":"Yolanda Mares-Gutiérrez ,&nbsp;Adrián Martínez-González ,&nbsp;Guillermo Salinas-Escudero ,&nbsp;Manuel García-Minjares ,&nbsp;Stephanie Liu ,&nbsp;Yvonne N. Flores","doi":"10.1016/j.opresp.2024.100325","DOIUrl":"10.1016/j.opresp.2024.100325","url":null,"abstract":"<div><h3>Introduction</h3><p>Although a major goal of preoperative evaluation is to identify risk factors and improve postoperative outcomes, current clinical guidelines in Mexico indicate that preoperative spirometry should only be performed on patients with pulmonary disease. The aim of this study was to compare the incidence of postoperative complications (POC), mortality, and risk factors among adults who did or did not undergo preoperative spirometry, based on their Assess Respiratory Risk in Surgical Patients in Catalonia (ARISCAT) risk level.</p></div><div><h3>Material and methods</h3><p>An observational, retrospective and comparative study design was used to identify 2059 patients from the <em>General Hospital of Mexico</em> who had an ARISCAT assessment during 2013–2017. Patients were classified in two groups: ARISCAT with spirometry (<em>n</em> <!-->=<!--> <!-->1306) and ARISCAT without spirometry (<em>n</em> <!-->=<!--> <!-->753). Chi-square, Fisher's exact test and the Student's <em>t</em>-tests were used to compare groups. Logistic regression was used to identify factors associated with an increased risk of POC and mortality.</p></div><div><h3>Results</h3><p>In the ARISCAT with spirometry group, 11% of patients had POC, compared with 48% of patients in the ARISCAT without spirometry group. High-risk ARISCAT patients who did not receive spirometry had higher mortality (18%), than those who underwent spirometry (0.4%). Logistic regression results indicate that not performing preoperative spirometry increases the probability of POC and mortality.</p></div><div><h3>Conclusions</h3><p>Our findings suggest that the combined use of preoperative spirometry and ARISCAT is associated with reduced POC and mortality. Future clinical guidelines should recommend the use of preoperative spirometry for patients with a moderate or high ARISCAT level in Mexico.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100325"},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000286/pdfft?md5=d0f326e798d3d29eb1cf10067ba775a3&pid=1-s2.0-S2659663624000286-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140779408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colaboración del farmacéutico comunitario en el infradiagnóstico de la enfermedad pulmonar obstructiva crónica (EPOC)","authors":"Francisco Javier Plaza Zamora ,&nbsp;Juan Marco Figueira-Gonçalves ,&nbsp;Javier de Miguel-Díez","doi":"10.1016/j.opresp.2024.100329","DOIUrl":"10.1016/j.opresp.2024.100329","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100329"},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000328/pdfft?md5=87187431e0964afb540c959d2b33b788&pid=1-s2.0-S2659663624000328-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140757221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Immunotherapy for Malignant Pleural Mesothelioma: From Emerging Strategies to Translational Insights","authors":"Rafael López-Castro ,&nbsp;Álvaro Fuentes-Martín ,&nbsp;Andrea Medina del Valle ,&nbsp;Tania García Peña ,&nbsp;José Soro García ,&nbsp;Leticia López González ,&nbsp;Ángel Cilleruelo Ramos","doi":"10.1016/j.opresp.2024.100323","DOIUrl":"https://doi.org/10.1016/j.opresp.2024.100323","url":null,"abstract":"<div><p>MPM stands as a rare malignancy necessitating improved therapeutic strategies due to its limited treatment choices and unfavorable prognosis. The advent of immune checkpoint inhibitors has heralded a paradigm shift in the therapeutic landscape of MPM, offering promising avenues across diverse clinical scenarios. In the context of advanced stages of the disease, Immune check-point inhibitors targeting programmed cell death protein 1 (PD-1) and cytotoxic T-lymphocyte-as-sociated protein 4 (CTLA-4), have exhibited encouraging potential in clinical trials, particularly manifesting efficacy among patients exhibiting disease progression following chemotherapy regimens. Innovative combination regimens, exemplified by the concurrent administration of nivolumab and ipilimumab, have demonstrated marked improvement in survival and patient's benefits. A deeper comprehension of the intricate genetic underpinnings of MPM, encompassing key mutations such as cyclin-dependent kinase inhibitor 2A (CDKN2A), neurofibromin 2 (NF2), and BRCA1-associated protein 1 (BAP1) mutations, has elucidated novel avenues for targeted therapeutic interventions. This review accentuates the transformative capacity of immunotherapy in revolutionizing the therapeutic outlook for MPM, thereby potentially translating into augmented survival rates and offering glimpses of new approaches on the horizon. Despite the persisting challenges, the synergistic crossroads of interdisciplinary research and collaborative clinical endeavors portend a hopeful landscape for MPM treatment.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100323"},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000262/pdfft?md5=c0973982c927d446d5a17c9dbccebafb&pid=1-s2.0-S2659663624000262-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140633480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asma","authors":"Celia Pinedo Sierra ,&nbsp;Elena Curto Sánchez ,&nbsp;Rocio Diaz Campos ,&nbsp;Tamara Hermida Valverde ,&nbsp;Silvia Sánchez-Cuellar ,&nbsp;Ana Fernández Tena","doi":"10.1016/j.opresp.2024.100324","DOIUrl":"https://doi.org/10.1016/j.opresp.2024.100324","url":null,"abstract":"<div><p>Asthma is a chronic inflammatory disease that affects about 5% of the world's population and generates high health and social costs. Proper management of the disease requires a correct diagnosis, based on objective measures of functional impairment, as well as symptom control and assessment of the future risk of exacerbations.</p><p>It has been estimated that 18% of asthma patients in Western Europe have severe asthma and approximately 50% of them have poor control. The severity of asthma is established based on the minimum maintenance treatment needs to achieve control. Asthma clinical practice guidelines recommend classifying severe patients into allergic asthma (T2); eosinophilic asthma (T2) and non-T2 asthma in order to establish the most appropriate treatment.</p><p>In recent decades, new biological therapies have been developed that can be applied according to the phenotype and endotype of asthma, allowing for selective and personalized treatment. These phenotypes and endotypes can change over time and therefore, the identification of biomarkers capable of predicting the severity, the course of the disease and the response to a given treatment seems essential. A large number of biomarkers have been studied in asthma, but so far only a few can be readily used in routine clinical practice. The application of omics technologies (epigenomics, genomics, transcriptomics, proteomics, metabolomics, lipidomics, etc.) for this purpose is still in the research phase.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100324"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000274/pdfft?md5=da83182976efb08c6744a01259b8601b&pid=1-s2.0-S2659663624000274-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140650838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malignant Pleural Mesothelioma: Analysis of 70 Cases in the Last Decade","authors":"Fernando Garcia-Prieto ,&nbsp;Sara Calero Pardo ,&nbsp;María Teresa Río Ramírez ,&nbsp;Araceli Abad Fernández","doi":"10.1016/j.opresp.2024.100326","DOIUrl":"10.1016/j.opresp.2024.100326","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100326"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000298/pdfft?md5=a905f3cb4ba467799e4586b3d6691ae4&pid=1-s2.0-S2659663624000298-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140774146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Terapias respiratorias domiciliarias: documento técnico de la Sociedad Española de Neumología y Cirugía Torácica (SEPAR) de apoyo institucional a la toma de decisiones","authors":"Pedro J. Marcos ,&nbsp;Alberto Fernández Villar ,&nbsp;Eduardo Márquez Martín ,&nbsp;María Teresa Ramírez Prieto ,&nbsp;Irene Cano Pumarega","doi":"10.1016/j.opresp.2024.100318","DOIUrl":"10.1016/j.opresp.2024.100318","url":null,"abstract":"<div><p>Home Respiratory Therapies (HRT) encompass a variety of treatments for patients with chronic respiratory diseases, administered at home over extended periods. The Service Providers of HRT (SPHRT) collaborate with hospital resources to address chronic respiratory diseases, acting as strategic partners. The contracting of HRT in the public health system involves contests where the SPHRT present technical and economic offers. The purpose of this document is to provide a technical basis that can assist professionals, SPHRT, and the administration in making decisions when calling for, evaluating, and deciding on such contests.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 2","pages":"Article 100318"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000213/pdfft?md5=68df135bc3821de51b62c8056e9588cd&pid=1-s2.0-S2659663624000213-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140775542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}