Open Respiratory Archives最新文献

{"title":"Nontuberculous Mycobacteria Isolates in Respiratory Samples and Mycobacterial Pulmonary Disease in an Area of Northern Spain","authors":"Javier Ugedo ,&nbsp;Eva Tabernero ,&nbsp;Lander Altube ,&nbsp;María Victoria Leal ,&nbsp;Julia Amaranta García","doi":"10.1016/j.opresp.2024.100353","DOIUrl":"10.1016/j.opresp.2024.100353","url":null,"abstract":"<div><h3>Introduction</h3><p>The epidemiology of nontuberculous mycobacteria (NTM) is not well known. In this study, we aimed to determine the incidence of NTM isolates and nontuberculous mycobacterial pulmonary disease (NTM-PD) in five closely located hospitals in an area of northern Spain and analyse differences between them.</p></div><div><h3>Material and methods</h3><p>Demographic, microbiological, clinical and radiological data were collected retrospectively from all patients with a NTM isolated from respiratory specimens at five hospitals between 2012 and 2019. <em>Mycobacterium gordonae</em> isolates were excluded. Once the data was collected, it was determined which patients met the NMT-PD criteria.</p></div><div><h3>Results</h3><p>594 patients were included in the study. The mean incidence rate of NTM isolates across all five hospitals in the period studied was 4.15 per 100,000 person-year, while the rate of NTM-PD was 1.2. The annual number of isolates showed an upward trend over this period, but the same did not occur in the number of cases of NTM-PD. The species most frequently isolated were <em>Mycobacterium avium</em> complex (MAC) and <em>Mycobacterium xenopi</em> and those most frequently causing disease were MAC and <em>Mycobacterium kansassi</em>. There were significant differences between the five centres.</p></div><div><h3>Conclusions</h3><p>Our results are in line with similar studies in Europe in terms of NTM isolation and NTM-PD incidence and species isolated; however, we do not see the upward trend in NTM-PD rates described elsewhere. The great variability in isolation and disease rates, as well as in species isolated in geographically close areas, underlines, in our opinion, the importance of local environmental factors.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 4","pages":"Article 100353"},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000754/pdfft?md5=cd7a94623e8b69dbc5cfcf9687832ac9&pid=1-s2.0-S2659663624000754-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141847946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Limited Use and Potential Implementation Hurdles of Telemedicine Tools for the Remote Management of Patients With Chronic Obstructive Pulmonary Disease Among Members of SEPAR","authors":"Marc Vila ,&nbsp;Javier de Miguel Diez ,&nbsp;Vinicius Rosa De Oliveira ,&nbsp;Alvar Agustí","doi":"10.1016/j.opresp.2024.100338","DOIUrl":"10.1016/j.opresp.2024.100338","url":null,"abstract":"<div><h3>Introduction</h3><p>Telemedicine (TM) can help in the management of chronic obstructive pulmonary disease (COPD). This study examines knowledge, current use and potential limitations for practical implementation of TM for the remoted management of COPD patients among members of the COPD area of SEPAR (<em>n</em> <!-->=<!--> <!-->3118).</p></div><div><h3>Methods</h3><p>An electronic survey was circulated three times to these 3118 health-care professionals. Their knowledge, current use and potential limitations for implementation of different forms of TM, including tele-monitoring, tele-education and self-care, tele-rehabilitation and mobile health, for the remote management of COPD patients were tabulated and described.</p></div><div><h3>Results</h3><p>Only 120 health-care professionals responded to the survey (3.9%). The rate of response varied greatly across different Autonomous Communities (AACC); 99.2% of responders declared being aware of TM, but only 60.5% knew about the different TM alternatives investigated here, and only 40.3% actually used some form of TM for their current management of patients with COPD. Of those using TM, 47.1% referred being satisfied with its use. Main identified barriers for implementation of TM in their institutions were technological limitations and data security.</p></div><div><h3>Conclusions</h3><p>The potential of TM for the clinical management of COPD is well known among interviewed health-care professionals, but only less than half used it currently. The potential for growth is therefore clear. We propose that SEPAR analyze critically this potential and promotes measures to achieve it for the benefit of COPD patients.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100338"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000419/pdfft?md5=a8c55ae1b2c834b10379a6f4efbbc260&pid=1-s2.0-S2659663624000419-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bronchiectasis","authors":"Beatriz Raboso ,&nbsp;Cristina Pou ,&nbsp;Rosa Abril ,&nbsp;Marta Erro ,&nbsp;Carlos Sánchez ,&nbsp;Carlos Manzano ,&nbsp;Ester Zamarrón ,&nbsp;Guillermo Suarez-Cuartin ,&nbsp;Jessica González","doi":"10.1016/j.opresp.2024.100339","DOIUrl":"https://doi.org/10.1016/j.opresp.2024.100339","url":null,"abstract":"<div><p>Non-cystic fibrosis bronchiectasis, a condition that remains relatively underrecognized, has garnered increasing research focus in recent years. This scientific interest has catalyzed advancements in diagnostic methodologies, enabling comprehensive clinical and molecular profiling. Such progress facilitates the development of personalized treatment strategies, marking a significant step toward precision medicine for these patients.</p><p>Bronchiectasis poses significant diagnostic challenges in both clinical settings and research studies. While computed tomography (CT) remains the gold standard for diagnosis, novel alternatives are emerging. These include artificial intelligence-powered algorithms, ultra-low dose chest CT, and magnetic resonance imaging (MRI) techniques, all of which are becoming recognized as feasible diagnostic tools.</p><p>The precision medicine paradigm calls for refined characterization of bronchiectasis patients by analyzing their inflammatory and molecular profiles. Research into the underlying mechanisms of inflammation and the evaluation of biomarkers such as neutrophil elastase, mucins, and antimicrobial peptides have led to the identification of distinct patient endotypes. These endotypes present variable clinical outcomes, necessitating tailored therapeutic interventions. Among these, eosinophilic bronchiectasis is notable for its prevalence and specific prognostic factors, calling for careful consideration of treatable traits.</p><p>A deeper understanding of the microbiome's influence on the pathogenesis and progression of bronchiectasis has inspired a holistic approach, which considers the multibiome as an interconnected microbial network rather than treating pathogens as solitary entities. Interactome analysis therefore becomes a vital tool for pinpointing alterations during both stable phases and exacerbations.</p><p>This array of innovative approaches has revolutionized the personalization of treatments, incorporating therapies such as inhaled mannitol or ARINA-1, brensocatib for anti-inflammatory purposes, and inhaled corticosteroids specifically for patients with eosinophilic bronchiectasis.</p></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100339"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000420/pdfft?md5=746651a2acdc9645e05819a9790987ad&pid=1-s2.0-S2659663624000420-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141486226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Respiratory Syncytial Virus in Patients With Chronic Respiratory Disease","authors":"Felipe Villar-Álvarez ,&nbsp;Alberto García-Ortega ,&nbsp;Marta Entrenas-Castillo","doi":"10.1016/j.opresp.2024.100345","DOIUrl":"10.1016/j.opresp.2024.100345","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100345"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000481/pdfft?md5=b47806e52673b4fb5a6438e89f656cec&pid=1-s2.0-S2659663624000481-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141415480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endobronchial Valves in the Management of Recurrent Hemoptysis: A Case Report","authors":"Alan Jhunior Solis Solis,&nbsp;Carmen Angela Centeno Clemente,&nbsp;Antoni Rosell Gratacos","doi":"10.1016/j.opresp.2024.100346","DOIUrl":"10.1016/j.opresp.2024.100346","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100346"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000493/pdfft?md5=2d3679de3279a7f594ac14e65dcc7c84&pid=1-s2.0-S2659663624000493-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141638202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung Cancer Diagnostic Delay Time and Related Variables","authors":"Jesús Allende-González ,&nbsp;José Antonio Gullón-Blanco ,&nbsp;Eduardo Sánchez-Vázquez ,&nbsp;Estela García-Coya ,&nbsp;Juan Cascón-Hernández ,&nbsp;Working Group of Asturian Society of Respiratory tract pathology (ASTURPAR)","doi":"10.1016/j.opresp.2024.100341","DOIUrl":"10.1016/j.opresp.2024.100341","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100341"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000444/pdfft?md5=beea068157eacab35b8fc1d1f89ee8e3&pid=1-s2.0-S2659663624000444-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141390568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sham CPAP as a Practical Preevaluation Technique for Home Mechanical Ventilation","authors":"Jose Mª Díaz ,&nbsp;Maria del Mar García ,&nbsp;Macarena Segura ,&nbsp;Antonio Antón","doi":"10.1016/j.opresp.2024.100347","DOIUrl":"10.1016/j.opresp.2024.100347","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100347"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S265966362400050X/pdfft?md5=9fe7d6b16d5a90a56346317ec9fb8db3&pid=1-s2.0-S265966362400050X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141638203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Tracheal Diverticulum in a Patient With Systemic Sclerosis: An Exceptional Case","authors":"Fernando Garcia-Prieto,&nbsp;Adriana Rodríguez Perojo,&nbsp;María Teresa Río Ramírez","doi":"10.1016/j.opresp.2024.100343","DOIUrl":"10.1016/j.opresp.2024.100343","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 3","pages":"Article 100343"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000468/pdfft?md5=67fd6bbec7b88c087a0f746e07212a97&pid=1-s2.0-S2659663624000468-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141399137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hodgkin Lymphoma Mimicking Lung Carcinoma","authors":"Julio Ricardo Torres Bermúdez ,&nbsp;Oriana Andreina Fernández González ,&nbsp;Vanessa Alzate Isaza","doi":"10.1016/j.opresp.2024.100350","DOIUrl":"10.1016/j.opresp.2024.100350","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 4","pages":"Article 100350"},"PeriodicalIF":0.0,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000535/pdfft?md5=5c8004c72a825bc18988822b335f650c&pid=1-s2.0-S2659663624000535-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploratory Bronchoalveolar Lavage Fluid Analyses Reveal a High Diversity of Microbiome in NTM Lung Disease and a Low Diversity of Microbiome in Bronchiectasis","authors":"Kohei Fujita ,&nbsp;Yuki Yamamoto ,&nbsp;Masahiro Kamita ,&nbsp;Kosei Tanaka ,&nbsp;Takeru Nakabayashi ,&nbsp;Takuma Imakita ,&nbsp;Issei Oi ,&nbsp;Osamu Kanai ,&nbsp;Tadashi Mio ,&nbsp;Kiminobu Tanizawa ,&nbsp;Yutaka Ito","doi":"10.1016/j.opresp.2024.100351","DOIUrl":"10.1016/j.opresp.2024.100351","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 4","pages":"Article 100351"},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2659663624000547/pdfft?md5=0104aa4ec828e86e0c70372ad2eb9cb8&pid=1-s2.0-S2659663624000547-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141961287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}