Daniel Manzur-Sandoval, Monserrat Echeverría-Ortuño, Luis Antonio Jiménez-Ruán, Gustavo Rojas-Velasco
{"title":"Stridor and Respiratory Failure as Presentation of a Aneurysm of the Brachiocephalic Trunk Mimicking a Mediastinal Tumor","authors":"Daniel Manzur-Sandoval, Monserrat Echeverría-Ortuño, Luis Antonio Jiménez-Ruán, Gustavo Rojas-Velasco","doi":"10.1016/j.opresp.2025.100433","DOIUrl":"10.1016/j.opresp.2025.100433","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"7 2","pages":"Article 100433"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143929373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Pérez-de Llano , Mª Gema Bonilla , Elisa Luzon , Francisco Ramos-Lima , Juan Carlos Miralles
{"title":"What We Know to Date About Early Treatment With Biologics in Severe Asthma: A Scoping Review About the Use of Biologics in Severe Asthma and Possible Parallels With Early Rheumatoid Arthritis","authors":"Luis Pérez-de Llano , Mª Gema Bonilla , Elisa Luzon , Francisco Ramos-Lima , Juan Carlos Miralles","doi":"10.1016/j.opresp.2025.100418","DOIUrl":"10.1016/j.opresp.2025.100418","url":null,"abstract":"<div><h3>Introduction</h3><div>Theoretically, an early intervention with biologics in severe asthma (SA) patients may attenuate inflammatory processes and potentially halt disease progression and remodeling. Changing the approach to a more preventive one could alter the course of the disease, avoid its progression, and improve the likelihood of achieving clinical remission. The aims of this study were to gather scientific evidence on this topic, to draw a parallel between SA and rheumathoid arthritis (RA) and to analyze the potential benefits of establishing early treatment in SA.</div></div><div><h3>Material and methods</h3><div>A systematic scoping review, conducted in accordance with the methodological guidance of the Arksey and O’Malley framework and focusing on early treatment intervention with biological drugs in SA and RA is presented.</div></div><div><h3>Results</h3><div>Evidence supports the early intervention with biologics in RA to improve outcomes. Evidence regarding early intervention with biologics in SA is scarce. To date, the literature reviewed suggests that better clinical condition of the patient and more preserved lung function at the onset of biological treatment, together with a shorter duration of asthma, are associated with better response to biologics.</div></div><div><h3>Conclusions</h3><div>Data suggests that the more preventive approach may lead to improved results. The scarcity of scientific evidence highlights the importance of pursuing this line of research.</div></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"7 2","pages":"Article 100418"},"PeriodicalIF":0.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Agüero , Juan Luis García-Rivero , Beatriz Abascal , Carlos Antonio Amado , Ignacio Fernandez-Olmo , Miguel Santibáñez , on behalf of the group of researchers of the ASTHMA-FENOP study
{"title":"FeNO Stability in Repeated Measurements in Asthma Patients During Three Consecutive Days","authors":"Juan Agüero , Juan Luis García-Rivero , Beatriz Abascal , Carlos Antonio Amado , Ignacio Fernandez-Olmo , Miguel Santibáñez , on behalf of the group of researchers of the ASTHMA-FENOP study","doi":"10.1016/j.opresp.2025.100417","DOIUrl":"10.1016/j.opresp.2025.100417","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"7 2","pages":"Article 100417"},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143610269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raúl Majo García , María Nélida Fernández-Martínez , Andrea Crespo Sedano , María Guadalupe Espinosa Villoria , Esther Alonso Sastre , Daniel Fernández-García
{"title":"Effectiveness of Cytisinicline Treatment in Hospital Smoking Units","authors":"Raúl Majo García , María Nélida Fernández-Martínez , Andrea Crespo Sedano , María Guadalupe Espinosa Villoria , Esther Alonso Sastre , Daniel Fernández-García","doi":"10.1016/j.opresp.2025.100414","DOIUrl":"10.1016/j.opresp.2025.100414","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"7 2","pages":"Article 100414"},"PeriodicalIF":0.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143610268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}