REC Interventional Cardiology最新文献

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[[Drug-coated balloons across different scenarios. Long-term single center experience]]. 不同场景下的药物包裹气球。长期的单中心体验[]。
IF 1.2
REC Interventional Cardiology Pub Date : 2025-02-24 eCollection Date: 2025-04-01 DOI: 10.24875/RECIC.M24000493
David Neves, Miguel Carias, Sílvia Alminhas, Renato Fernandes, Lino Patrício
{"title":"[[Drug-coated balloons across different scenarios. Long-term single center experience]].","authors":"David Neves, Miguel Carias, Sílvia Alminhas, Renato Fernandes, Lino Patrício","doi":"10.24875/RECIC.M24000493","DOIUrl":"10.24875/RECIC.M24000493","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 2","pages":"119-121"},"PeriodicalIF":1.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[[Percutaneous treatment of the left main coronary artery in older adults. Impact of frailty on mid-term results]]. 老年人冠状动脉左主干的经皮治疗。虚弱对中期结果的影响[]。
IF 1.2
REC Interventional Cardiology Pub Date : 2025-02-24 eCollection Date: 2025-01-01 DOI: 10.24875/RECIC.M24000471
Ignacio Gallo, Francisco Hidalgo, Rafael González-Manzanares, Marcos Alvarado, Jorge Perea, Javier Suárez de Lezo, Miguel Romero, Soledad Ojeda, Manuel Pan
{"title":"[[Percutaneous treatment of the left main coronary artery in older adults. Impact of frailty on mid-term results]].","authors":"Ignacio Gallo, Francisco Hidalgo, Rafael González-Manzanares, Marcos Alvarado, Jorge Perea, Javier Suárez de Lezo, Miguel Romero, Soledad Ojeda, Manuel Pan","doi":"10.24875/RECIC.M24000471","DOIUrl":"10.24875/RECIC.M24000471","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>In elderly and frail patients, there is limited evidence on the therapeutic management of left main coronary artery (LM) disease. The objective of this study was to evaluate mid-term clinical outcomes in older adults undergoing percutaneous coronary intervention (PCI) of LM.</p><p><strong>Methods: </strong>We conducted a retrospective study including all older patients (≥ 75 years) undergoing LM-PCI at a high-volume center between 2017 and 2021. The primary endpoint was a composite of major adverse cardiovascular events (MACE). Patients were grouped according to the presence of frailty based on the FRAIL scale. Inverse probability of treatment weighting was used to account for clinical differences between the 2 groups.</p><p><strong>Results: </strong>A total of 140 patients were included in the study (median age 80 [78-84]; 36% women). Of them, 49% met the criteria for frailty. After a median follow-up of 19 [5-35] months, 40 MACE (29%) were recorded. The all-cause death rate was 32%. There were no differences in the risk of MACE between frailty groups, but patients with frailty had an increased risk of all-cause mortality (HR<sub>adj</sub>, 1.95 [1.02-3.75]; P = .046).</p><p><strong>Conclusions: </strong>LM-PCI in older adults with multiple associated comorbidities could be considered a feasible option in this special population. The rate of MACE at follow-up was acceptable. Frailty was associated with a worse prognosis in terms of all-cause mortality at follow-up.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 1","pages":"6-14"},"PeriodicalIF":1.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[[TAVI for aortic regurgitation using dedicated devices. A systematic review]]. 使用专用装置治疗主动脉瓣反流。系统回顾[]。
IF 1.2
REC Interventional Cardiology Pub Date : 2025-02-24 eCollection Date: 2025-01-01 DOI: 10.24875/RECIC.M24000480
Ahmed Hassan, Mahmoud Abdelshafy, Rehab Adel Diab, Hendrik Wienemann, Matti Adam, Santiago García, Marwan Saad, Mohammad Abdelghani
{"title":"[[TAVI for aortic regurgitation using dedicated devices. A systematic review]].","authors":"Ahmed Hassan, Mahmoud Abdelshafy, Rehab Adel Diab, Hendrik Wienemann, Matti Adam, Santiago García, Marwan Saad, Mohammad Abdelghani","doi":"10.24875/RECIC.M24000480","DOIUrl":"10.24875/RECIC.M24000480","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Transcatheter aortic valve implantation (TAVI) for pure aortic regurgitation is challenging due to inadequate device anchoring and increased risks of device embolization and paravalvular regurgitation (PVR). This study aimed to review the safety and efficacy of TAVI for aortic regurgitation with devices specifically designed for this indication.</p><p><strong>Methods: </strong>A comprehensive search of PubMed, Web of Science, Cochrane Library, and major conference archives up to April 2024 identified 143 unique results based on predefined criteria.</p><p><strong>Results: </strong>Fifteen studies (n = 788 patients) were included, with J-Valve used in 357 patients and JenaValve in 431. Men represented 51% of the cohort, with a mean age of 74.7 ± 8.8 years and an STS-PROM score of 5.8 ± 4.9%. Transapical and transfemoral access routes were used in 62.7% and 37.3% of patients, respectively. Overall, procedural success was achieved in 95.9% of cases; surgical conversion was required in 1.8%, device migration/embolization occurred in 3.2%, and a second valve (in-valve) was required in 2.0% of patients. At 30 days, 95.5% of patients were alive, and device success was reported in 93.3% of cases. Mild PVR was observed in 18.0% of patients, moderate-to-severe PVR in 1.7%, and permanent pacemaker implantation (PPI) was required in 13.0%. In studies focusing on transfemoral procedures (all using JenaValve), the pooled estimates showed a procedural success rate of 97.8% (95%CI, 94.4-100), device success of 97.0% (95%CI, 94.8-99.2), 30-day mortality of 1.96% (95%CI, 0.20-3.72), moderate-to-severe PVR of 0.47% (95%CI, 0.00-1.47), and PPI requirement of 18.7% (95%CI, 13.9-23.4).</p><p><strong>Conclusions: </strong>This systematic review of relatively small observational studies demonstrates the safety and favorable early outcomes of TAVI using J-Valve and JenaValve in patients with pure aortic regurgitation, especially when the transfemoral approach is used. Nevertheless, the need for PPI remains frequent.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 1","pages":"29-43"},"PeriodicalIF":1.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[[Percutaneous coronary intervention of the left main in the elderly: a reasonable option]]. 老年人左主干经皮冠状动脉介入治疗:一种合理的选择。
IF 1.1
REC Interventional Cardiology Pub Date : 2025-02-24 eCollection Date: 2025-01-01 DOI: 10.24875/RECIC.M24000477
Franz-Josef Neumann
{"title":"[[Percutaneous coronary intervention of the left main in the elderly: a reasonable option]].","authors":"Franz-Josef Neumann","doi":"10.24875/RECIC.M24000477","DOIUrl":"10.24875/RECIC.M24000477","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 1","pages":"1-2"},"PeriodicalIF":1.1,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[[Infective endocarditis in surgical versus transcatheter aortic valve implantation. Same incidence and same prognosis?]]. 感染性心内膜炎与经导管主动脉瓣置入术的比较。相同的发病率和相同的预后?
IF 1.1
REC Interventional Cardiology Pub Date : 2025-02-19 eCollection Date: 2025-01-01 DOI: 10.24875/RECIC.M25000500
Ignacio J Amat-Santos, J Alberto San Román
{"title":"[[Infective endocarditis in surgical versus transcatheter aortic valve implantation. Same incidence and same prognosis?]].","authors":"Ignacio J Amat-Santos, J Alberto San Román","doi":"10.24875/RECIC.M25000500","DOIUrl":"10.24875/RECIC.M25000500","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 2","pages":"69-70"},"PeriodicalIF":1.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[[Results after implementation of the European protocol in the management of post-TAVI conduction disorders]]. [欧洲方案在tavi后传导障碍管理中的实施结果]。
IF 1.2
REC Interventional Cardiology Pub Date : 2025-02-06 eCollection Date: 2025-04-01 DOI: 10.24875/RECIC.M24000499
Domingo López Vázquez, Xacobe Flores Ríos, Fausto de Andrés Cardelle, Carmen Vidau Getán, Ramón Calviño Santos, José Manuel Vázquez Rodríguez
{"title":"[[Results after implementation of the European protocol in the management of post-TAVI conduction disorders]].","authors":"Domingo López Vázquez, Xacobe Flores Ríos, Fausto de Andrés Cardelle, Carmen Vidau Getán, Ramón Calviño Santos, José Manuel Vázquez Rodríguez","doi":"10.24875/RECIC.M24000499","DOIUrl":"10.24875/RECIC.M24000499","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 2","pages":"122-124"},"PeriodicalIF":1.2,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[[New scoring balloon to treat moderate-to-severe calcified coronary lesions. The first-in-man Naviscore study]]. 新型评分球囊治疗中重度钙化冠状动脉病变。Naviscore的首次人体研究[]。
IF 1.2
REC Interventional Cardiology Pub Date : 2025-02-03 eCollection Date: 2025-04-01 DOI: 10.24875/RECIC.M24000487
Antonio Serra Peñaranda, Estefanía Fernández Peregrina, Marcelo Jiménez Kockar, Bruno García Del Blanco, Sebastián Romani, Javier Martín Moreiras, Eduardo Pinar Bermúdez, Alberto Rodrigues, Soledad Ojeda, Nieves Gonzalo López, Ander Regueiro, Ana Serrador Frutos
{"title":"[[New scoring balloon to treat moderate-to-severe calcified coronary lesions. The first-in-man Naviscore study]].","authors":"Antonio Serra Peñaranda, Estefanía Fernández Peregrina, Marcelo Jiménez Kockar, Bruno García Del Blanco, Sebastián Romani, Javier Martín Moreiras, Eduardo Pinar Bermúdez, Alberto Rodrigues, Soledad Ojeda, Nieves Gonzalo López, Ander Regueiro, Ana Serrador Frutos","doi":"10.24875/RECIC.M24000487","DOIUrl":"10.24875/RECIC.M24000487","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Calcified coronary lesions are becoming more prevalent and remain therapeutically challenging. Although a variety of devices can be used in this setting, cutting balloons (CB) and scoring balloons (SB) are powerful and simple tools to treat calcified plaques vs more complex devices. However, there are some drawbacks: these are stiff and bulky balloons that, as a first device, complicate lesion crossing and navigability in the presence of tortuosity, thus making it extremely difficult to recross once the balloon has been inflated. The objective of this study was to evaluate the safety and efficacy profile of the new Naviscore SB designed to overcome these drawbacks.</p><p><strong>Methods: </strong>The first-in-man Naviscore Registry is a multicenter, prospective trial that included 85 patients with moderate (34%) or severe (66%) de novo calcified coronary lesions located in the native arteries, with stable angina and an indication for percutaneous coronary intervention.</p><p><strong>Results: </strong>Mean age was 71 ± 11 years, with a high prevalence of comorbidities. Used as the first device, the Naviscore was able to cross 76% of the lesions and was used in 98% of the cases effectively modifying the calcified plaque. Procedural success was achieved in 94% of cases. Basal stenosis of 81 ± 12% decreased to 33 ± 8.5% after Naviscore and to 7.5 ± 2.6% after stent implantation. There were no major adverse cardiovascular events during admission. Perforation, device entrapment or flow-limiting dissections did not occur-only type A/B dissections in 13%-which were fixed with stent implantation. Device performance was deemed superior to the usual SB or CB used by the participant centers.</p><p><strong>Conclusions: </strong>The Naviscore SB is very effective crossing severely calcified lesions as the first device, with effective plaque modification, stent expansion and an excellent safety profile. The Naviscore improves the behavior of current CB and SB. Due to its simplicity of use and performance, the Naviscore can be the first-choice SB to treat significant calcified lesions.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 2","pages":"91-98"},"PeriodicalIF":1.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[[Broadening perspectives in interventional cardiology. The role of EAPCI in supporting interventional cardiologists]]. 介入心脏病学拓宽视野。EAPCI在支持介入心脏病专家中的作用[]。
IF 1.2
REC Interventional Cardiology Pub Date : 2025-01-30 eCollection Date: 2025-04-01 DOI: 10.24875/RECIC.M24000496
Erik Rafflenbeul, Mario Iannaccone, Aleksandra Gasecka, Nicola Ryan, Alaide Chieffo
{"title":"[[Broadening perspectives in interventional cardiology. The role of EAPCI in supporting interventional cardiologists]].","authors":"Erik Rafflenbeul, Mario Iannaccone, Aleksandra Gasecka, Nicola Ryan, Alaide Chieffo","doi":"10.24875/RECIC.M24000496","DOIUrl":"10.24875/RECIC.M24000496","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 2","pages":"71-74"},"PeriodicalIF":1.2,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[[Prognostic value of global plaque volume calculated from the 3D reconstruction of the coronary tree in patients without significant coronary artery disease. A multicenter study]]. [3]无明显冠状动脉疾病患者冠状动脉树三维重建计算整体斑块体积的预后价值。多中心研究[]。
IF 1.2
REC Interventional Cardiology Pub Date : 2025-01-29 eCollection Date: 2025-04-01 DOI: 10.24875/RECIC.M24000498
Carlos Cortés, Julio Ruiz-Ruiz, Fernando Rivero, Ramón López-Palop, Octavio Jiménez, Alfonso Freites, Luis R Gonçalves-Ramírez, María Rosario Ortas Nadal, Sara Blasco, Mario García-Gómez, Clara Fernández, Luca Scorpiglione, J Alberto San Román Calvar, Ignacio J Amat-Santos
{"title":"[[Prognostic value of global plaque volume calculated from the 3D reconstruction of the coronary tree in patients without significant coronary artery disease. A multicenter study]].","authors":"Carlos Cortés, Julio Ruiz-Ruiz, Fernando Rivero, Ramón López-Palop, Octavio Jiménez, Alfonso Freites, Luis R Gonçalves-Ramírez, María Rosario Ortas Nadal, Sara Blasco, Mario García-Gómez, Clara Fernández, Luca Scorpiglione, J Alberto San Román Calvar, Ignacio J Amat-Santos","doi":"10.24875/RECIC.M24000498","DOIUrl":"10.24875/RECIC.M24000498","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The use of coronary physiology is essential to guide revascularization in patients with stable coronary artery disease. However, some patients without significant angiographic coronary artery disease will experience cardiovascular events at the follow-up. This study aims to determine the prognostic value of the global plaque volume (GPV) in patients with stable coronary artery disease without functionally significant lesions at a 5-year follow-up.</p><p><strong>Methods: </strong>We conducted a multicenter, observational, and retrospective cohort study with a 5-year follow-up. A total of 277 patients without significant coronary artery disease treated with coronary angiography in 2015 due to suspected stable coronary artery disease were included in the study. The 3 coronary territories were assessed using quantitative flow ratio, calculating the GPV by determining the difference between the luminal volume and the vessel theoretical reference volume.</p><p><strong>Results: </strong>The mean GPV was 170.5 mm<sup>3</sup>. A total of 116 patients (42.7%) experienced major adverse cardiovascular events (MACE) at the follow-up, including cardiac death (11%), myocardial infarction (2.6%), and unexpected hospital admissions (38.1%). Patients with MACE had a significantly higher GPV (231.6 mm<sup>3</sup> vs 111.8 mm<sup>3</sup>; <i>P</i> < .001). The optimal GPV cut-off point for predicting events was 44 mm<sup>3</sup>. Furthermore, in the multivariate analysis conducted, plaque volume, diabetes, hypertension, age, dyslipidemia, smoking, age, and GPV > 44 mm<sup>3</sup> turned out to be independent predictors of MACE.</p><p><strong>Conclusions: </strong>GPV, calculated from the three-dimensional reconstruction of the coronary tree, is an independent predictor of events in patients with stable coronary artery disease without significant lesions. A GPV > 44 mm<sup>3</sup> is an optimal cut-off point for predicting events.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 2","pages":"109-114"},"PeriodicalIF":1.2,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[[Long-term prognostic impact of the left anterior descending coronary artery as the STEMI-related culprit vessel: subanalysis of the EXAMINATION-EXTEND trial]]. [[左冠状动脉前降支作为stemi相关罪魁血管的长期预后影响:EXAMINATION-EXTEND试验的亚分析]]。
IF 1.2
REC Interventional Cardiology Pub Date : 2025-01-29 eCollection Date: 2025-04-01 DOI: 10.24875/RECIC.M24000491
Pablo Vidal-Calés, Kamil Bujak, Riccardo Rinaldi, Anthony Salazar-Rodríguez, Luis Ortega-Paz, Josep Gómez-Lara, Víctor Jiménez-Díaz, Marcelo Jiménez, Pilar Jiménez-Quevedo, Roberto Diletti, Pascual Bordes, Gianluca Campo, Antonio Silvestro, Jaume Maristany, Xacobe Flores, Antonio De Miguel-Castro, Andrés Íñiguez, Alfonso Ielasi, Maurizio Tespili, Mattie Lenzen, Nieves Gonzalo, Matteo Tebaldi, Simone Biscaglia, Rafael Romaguera, Joan Antoni Gómez-Hospital, Patrick W Serruys, Manel Sabaté, Salvatore Brugaletta
{"title":"[[Long-term prognostic impact of the left anterior descending coronary artery as the STEMI-related culprit vessel: subanalysis of the EXAMINATION-EXTEND trial]].","authors":"Pablo Vidal-Calés, Kamil Bujak, Riccardo Rinaldi, Anthony Salazar-Rodríguez, Luis Ortega-Paz, Josep Gómez-Lara, Víctor Jiménez-Díaz, Marcelo Jiménez, Pilar Jiménez-Quevedo, Roberto Diletti, Pascual Bordes, Gianluca Campo, Antonio Silvestro, Jaume Maristany, Xacobe Flores, Antonio De Miguel-Castro, Andrés Íñiguez, Alfonso Ielasi, Maurizio Tespili, Mattie Lenzen, Nieves Gonzalo, Matteo Tebaldi, Simone Biscaglia, Rafael Romaguera, Joan Antoni Gómez-Hospital, Patrick W Serruys, Manel Sabaté, Salvatore Brugaletta","doi":"10.24875/RECIC.M24000491","DOIUrl":"10.24875/RECIC.M24000491","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>There is limited data on the impact of the culprit vessel on very long-term outcomes after ST-elevation myocardial infarction (STEMI). The aim was to analyze the impact of the left anterior descending coronary artery (LAD) as the culprit vessel of STEMI on very long-term outcomes.</p><p><strong>Methods: </strong>We analyzed patients included in the EXAMINATION-EXTEND study (NCT04462315) treated with everolimus-eluting stents or bare-metal stents after STEMI (1498 patients) and stratified according to the culprit vessel (LAD vs other vessels). The primary endpoint was the patient-oriented composite endpoint (POCE), including all-cause mortality, myocardial infarction (MI) or revascularization at 10 years. Secondary endpoints were individual components of POCE, device-oriented composite endpoint and its individual components and stent thrombosis. We performed landmark analyses at 1 and 5 years. All endpoints were adjusted with multivariable Cox regression models.</p><p><strong>Results: </strong>The LAD was the culprit vessel in 631 (42%) out of 1498 patients. The LAD-STEMI group had more smokers, advanced Killip class and worse left ventricular ejection fraction. Conversely, non-LAD-STEMI group showed more peripheral vascular disease, previous MI, or previous PCI. At 10 years, no differences were observed between groups regarding POCE (34.9% vs 35.4%; adjusted hazard ratio [HR], 0.95; 95% confidence interval [95%CI], 0.79-1.13; <i>P</i> = .56) or other endpoints. The all-cause mortality rate was higher in the LAD-STEMI group (<i>P</i> = .041) at 1-year.</p><p><strong>Conclusions: </strong>In a contemporary cohort of STEMI patients, there were no differences in POCE between LAD as the STEMI-related culprit vessel and other vessels at 10 years follow-up. However, all-cause mortality was more common in the LAD-STEMI group within the first year after STEMI.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 2","pages":"99-108"},"PeriodicalIF":1.2,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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