REC Interventional Cardiology最新文献

{"title":"Left atrial appendage occlusion plus oral anticoagulation in stroke patients despite ongoing anticoagulation: rationale and design of the ADD-LAAO clinical trial.","authors":"Sergio Amaro, Ignacio Cruz-González, Rodrigo Estévez-Loureiro, Xavier Millan, Luis Nombela-Franco, Joan Gómez-Hospital, Eduardo Flores-Umanzor, Luis López-Mesonero, José Maciñeiras, Lluis Prats-Sánchez, Patricia Simal, Pere Cardona, Luis Teruel, Pedro Cepas-Guillén, Dabit Arzamendi, Xavier Freixa","doi":"10.24875/RECICE.M25000507","DOIUrl":"10.24875/RECICE.M25000507","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The prevalence of atrial fibrillation and the number of patients experiencing ischemic strokes despite oral anticoagulation (OAC) are both on the rise, which presents a significant challenge due to the absence of clear and uniform treatment recommendations for these patients. To date, there is no formal combination merging into a high anticoagulant efficacy profile while keeping a low bleeding risk. Transcatheter left atrial appendage occlusion (LAAO) in combination with OAC might provide a balance between safety and efficacy. The objective of this study is to evaluate whether, in ischemic stroke patients, despite anticoagulation, the combination of LAAO plus long-term anticoagulation-direct oral anticoagulants or vitamin K antagonist when indicated-is associated with a lower rate of recurrent cardioembolic events at 12 months vs the optimal medical therapy recommended by the neurologist.</p><p><strong>Methods: </strong>A total of 380 patients with ischemic stroke despite OAC will be included. Patients will be randomized on a 1:1 ratio to receive the optimal medical therapy (control) or the combination of LAAO plus OAC or OAC. The primary endpoint of the study will be the occurrence of a cardioembolic event-ischemic stroke or arterial peripheral embolism-within the first 12 months after inclusion.</p><p><strong>Conclusions: </strong>This study is one of the first randomized clinical trials to compare the LAAO plus OAC combination and optimal medical therapy in patients who have experienced ischemic strokes despite being on OAC. If results confirm the superiority of LAAO plus OAC, it could lead to a paradigm shift in treatment guidelines for these patients.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"140-145"},"PeriodicalIF":1.1,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional assessment in acute coronary syndrome: a systematic review of acute versus staged interventions.","authors":"Federico Vergni, Silvia Buscarini, Leonardo Ciurlanti, Filippo Luca Gurgoglione, Francesco Pellone, Mario Luzi","doi":"10.24875/RECICE.M25000511","DOIUrl":"10.24875/RECICE.M25000511","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Several tools have been implemented to assess the functional significance of coronary lesions. Their reliability in the management of acute coronary syndrome (ACS) might be affected by alterations in the acute phase that go beyond the affected area. Our main objective was to evaluate the reliability of invasive physiological indices for non-culprit lesions (NCL) in patients with ACS.</p><p><strong>Methods: </strong>We conducted a systematic review across ClinicalTrials.gov, Embase, Google Scholar, PubMed, and Web of Science from inception through 5 December 2024. Additionally, a citation analysis and web searches were conducted.</p><p><strong>Results: </strong>A total of 20 articles, with 4379 patients were included in the analysis. The main study design is a cohort study. The following methods were compared between acute and staged interventions: <i>a)</i> angiography-derived; <i>b)</i> hyperemic; and <i>c)</i> non-hyperemic indices. A significant difference in fractional flow reserve, instantaneous wave-free ratio, and quantitative flow ratio was found in one or more articles. There were no articles reporting any important changes in the Murray law-based quantitative flow ratio, resting distal-to-aortic coronary pressure ratio, or vessel fractional flow reserve. However, these indices rely on retrospective and/or limited data. All significant variations were observed in cohorts of ST-segment elevation myocardial infarction. Unlike quantitative flow ratio, the fractional flow reserve and instantaneous wave-free ratio demonstrated consistent directions of change towards lower and higher values, respectively. Prospective cohorts and randomized controlled trials including non-ST-segment elevation acute coronary syndrome did not prove the existence of significant differences between acute and follow-up fractional flow reserve.</p><p><strong>Conclusions: </strong>Physiological methods lack complete reliability for evaluating NCL during acute ST-segment elevation myocardial infarction. However, considering directions of change, fractional flow reserve is suitable for guiding the revascularization of acute positive NCL. Conversely, instantaneous wave-free ratio can be used to defer the revascularization of negative NCL. In non-ST-segment elevation acute coronary syndrome, fractional flow reserve is appropriate for assessing NCL within the acute phase.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"169-177"},"PeriodicalIF":1.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resúmenes presentados al 36 Congreso de la Asociación de Cardiología Intervencionista de la Sociedad Española de Cardiología. Santiago de Compostela, 4-6 de junio de 2025.","authors":"","doi":"10.24875/RECIC.M25000531","DOIUrl":"10.24875/RECIC.M25000531","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"C1-C14"},"PeriodicalIF":1.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Debate: TAVI prosthesis selection for severe calcification. The balloon-expandable technology approach.","authors":"Cristóbal A Urbano-Carrillo","doi":"10.24875/RECICE.M25000512","DOIUrl":"10.24875/RECICE.M25000512","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"178-180"},"PeriodicalIF":1.1,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Debate: TAVI prosthesis selection for severe calcification. The self-expandable technology approach.","authors":"Raquel Del Valle Fernández","doi":"10.24875/RECICE.M25000515","DOIUrl":"10.24875/RECICE.M25000515","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"181-183"},"PeriodicalIF":1.1,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fast-track TAVI: establishing a new standard of care.","authors":"Lluís Asmarats, Dabit Arzamendi","doi":"10.24875/RECIC.M25000515","DOIUrl":"10.24875/RECIC.M25000515","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"138-139"},"PeriodicalIF":1.1,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter closure of multiperforated atrial septal defect.","authors":"Luis Cerdán Ferreira, Georgina Fuertes Ferre, Juan Sánchez-Rubio Lezcano, Marta López Ramón","doi":"10.24875/RECICE.M25000510","DOIUrl":"10.24875/RECICE.M25000510","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Multi-fenestrated atrial septal defects (mASD) pose both diagnostic and therapeutic challenges. This study aimed to compare the outcomes of transcatheter closure in patients with mASD vs those with a single ASD at our center.</p><p><strong>Methods: </strong>We conducted a retrospective, single-center study including adult patients who underwent transcatheter ASD closure from October 2014 through October 2024. Demographic, echocardiographic, and hemodynamic data were collected, with a the 6-month follow-up.</p><p><strong>Results: </strong>A total of 67 patients were included, 12 of whom (18%) exhibited mASD. Patients with mASD were younger (42 vs 54 years) and more frequently presented with an interatrial septal aneurysm (91% vs 27%; P = .001). The use of multiple occlusion devices was more common in patients with mASD (34% vs 4%; P = .008). Complications were rare (5.9%) and none occurred in the mASD group. Procedural outcomes, including residual shunt and right ventricular remodeling at the follow-up, were comparable between groups.</p><p><strong>Conclusions: </strong>Transcatheter closure of mASD is both a safe and feasible procedure, with clinical outcomes similar to those observed in patients with a single ASD.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"164-168"},"PeriodicalIF":1.1,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of ultrasound renal denervation reducing blood pressure: a systematic review and meta-analysis.","authors":"Juan Miguel Guerrero-Hernández, Cristian Jesús Palomino-Ojeda, Lissette Haydee García-Mena, José Luis Maldonado-García, Óscar Ángel Vedia-Cruz, José Antonio García-Donaire, Iván Javier Núñez-Gil","doi":"10.24875/RECICE.M25000509","DOIUrl":"10.24875/RECICE.M25000509","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Ultrasound renal denervation (uRDN) has emerged as an innovative therapeutic approach for the treatment of hypertension. However, its efficacy compared to medication remains uncertain. We aimed to assess the efficacy profile of uRDN vs sham groups focusing on its impact on daytime ambulatory blood pressure, 24-hour blood pressure, home blood pressure and office blood pressure.</p><p><strong>Methods: </strong>We conducted a systematic search across Embase, PubMed, and Cochrane Library databases from their inception up 1 November 2024 to identify randomized controlled trials evaluating the efficacy of uRDN. Statistical analyses were performed using RevMan 6.3 software, utilizing the mean and standard deviation method to calculate mean differences with a 95% confidence interval (95%CI).</p><p><strong>Results: </strong>A total of 4 studies were included in the final analysis with 642 patients. uRDN significantly reduced daytime ambulatory systolic blood pressure (SBP) (-5.12 mmHg; 95%CI, -6.07 to -4.16; P ≤ .00001), 24-h SBP (-4.87 mmHg; 95%CI, -6.53 to -3.21]; P ≤ .00001), office SBP (-5.03 mmHg; 95%CI, -6.27 to -3.79; P ≤ .00001) and showed a decrease in patient medication 6 months after the procedure.</p><p><strong>Conclusions: </strong>Using uRDN leads to a lower blood pressure in patients within 2 months following the procedure. Additionally, after 6 months a significant decrease in drug use is observed.This meta-analysis protocol was registered on PROSPERO on 7 July 2024 (CRD42024562852).</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"154-163"},"PeriodicalIF":1.1,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early discharge following transcatheter aortic valve implantation: a feasible goal during the learning curve?","authors":"Raquel Pimienta González, Alejandro Quijada Fumero, Marcos Farráis Villalba, Javier Lorenzo González, Ana Laynez Carnicero, Alejandro Iriarte Plasencia, Gabriela Noemí González Chiale, Cristina López Ferraz, Juan Manuel Llanos Gómez, Martín Caicoya Boto, Ángel López Castillo, Julio Salvador Hernández Afonso","doi":"10.24875/RECICE.M25000508","DOIUrl":"10.24875/RECICE.M25000508","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Although early discharge protocols after transcatheter aortic valve implantation (TAVI) have demonstrated to be safe in various studies, they are usually applied in high-experience centers. This study analyzes the length of stay of the first 100 patients undergoing TAVI in a center without on-site cardiac surgery, differentiating between very early (< 24 hours), early (24-48 hours), and late discharge (> 48 hours). Furthermore, the study evaluates the feasibility of an early discharge protocol during the team's learning curve.</p><p><strong>Methods: </strong>We conducted a prospective observational study from April 2022 through January 2024. A pre- and postoperative management protocol was implemented, including assessments in the Valvular Heart Disease Clinic, admission to the cardiac surgery intensive care unit with electrocardiographic monitoring, and specific discharge criteria in full compliance with an established protocol for the management of conduction disorders. Early follow-up evaluations were performed in the outpatiently after discharge.</p><p><strong>Results: </strong>A total of 100 patients (50% women) were included, with a mean age of 82.4 ± 5.3 years and a EuroSCORE II score of 4.38 ± 5.1%. The median length of stay was 2 days (range, 1-19). A total of 27.27% of patients were discharged in < 24 hours, 48.49% within the 24-48 hours following implantation, and 24.24% 48 hours later. The 30-day cardiovascular mortality rate was 1%. A total of 6 patients were readmitted with procedural complications within the first 30 days.</p><p><strong>Conclusions: </strong>The implementation of a standardized care protocol allows for early and safe discharge in most patients, even during the team's learning cuve.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"146-153"},"PeriodicalIF":1.1,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Venous congestion in a d-TGA patient after Mustard procedure.","authors":"Francisco Javier Ruperti-Repilado, Félix Coserria-Sánchez, Amadeo Wals-Rodríguez, Agustín Guisado, José Díaz-Fernández, Pastora Gallego","doi":"10.24875/RECICE.M25000500","DOIUrl":"10.24875/RECICE.M25000500","url":null,"abstract":"","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"7 3","pages":"193-194"},"PeriodicalIF":1.1,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}