M. Mannil, Chandini Kadian, Elisabeth Futterlieb, M. Sereda
{"title":"Rehabilitation in Charcot-Marie-Tooth disease type 1","authors":"M. Mannil, Chandini Kadian, Elisabeth Futterlieb, M. Sereda","doi":"10.47795/mmvg6026","DOIUrl":"https://doi.org/10.47795/mmvg6026","url":null,"abstract":"Charcot-Marie-Tooth disease is the most common inherited peripheral neuropathy with a prevalence of approximately 1 in 2,500 [1]. The most common subtype is the autosomal dominant type 1A, which is caused by an intrachromosomal duplication on chromosome 17p11.2 [2,3]. A consecutive primary loss of the myelin sheath leads to secondary axonal degeneration. Characteristic clinical findings include distally pronounced muscle wasting, secondary skeletal deformities, sensory loss, and reduced deep tendon reflexes [4,5]. The individual clinical phenotypes vary, even among monozygotic twins [6]. They range from sub-clinical manifestations to rare cases of wheelchair-bound patients. Overall, the quality of life is significantly impaired [7]. Despite ongoing research, no curative treatments are currently available [8]. A recently published ascorbic acid trial showed no significant effect on the clinical phenotype of CMT1A patients [9,32,36]. Nevertheless, physical therapy and moderate exercises are proven to be positively disease-modifying. While a cure lies beyond the scope of physical therapy, it may prevent the rapid aggravation of the clinical phenotype [10,11,17]. Recent studies suggest that CMT patients experience physical as well as mental benefits from rehabilitation programmes, but they also perceive that the performed exercises were not specifically designed to their needs [11]. In fact, there is little evidence-based data and no common consensus on rehabilitation in patients suffering from Charcot-Marie-Tooth disease.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83113295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatigue after Acquired Brain Injury: a model to guide clinical management","authors":"M. Donna, Jaqui Wheatcroft, F. Gracey","doi":"10.47795/jver9544","DOIUrl":"https://doi.org/10.47795/jver9544","url":null,"abstract":"Donna Malley is an Occupational Therapy Clinical Specialist working at The Oliver Zangwill Centre for Neuropsychological Rehabilitation based in Ely, part of Cambridgeshire Community Services NHS Trust. She is currently undertaking a NIHR CLAHRC East of England Fellowship. Her clinical and research interests include process and outcomes of holistic neuropsychological rehabilitation and management of fatigue following acquired brain injury. She has jointly produced a booklet on Managing Fatigue after Brain Injury for Headway with Jacqui Wheatcroft (nee Cooper) that won the BMA Patient Information award in 2009.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86597533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Social Cognition Interventions in Neuro-Rehabilitation: An Overview","authors":"Giles Yeates","doi":"10.47795/alua9018","DOIUrl":"https://doi.org/10.47795/alua9018","url":null,"abstract":"This article provides an overview of interventions developed and trialled in the embryonic field of social cognition neuro-rehabilitation. Interventions are categories under the headings of explicit skills training, embodied/relational interventions, and relational approaches. The assessment and treatment of social neuropsychological impairments have received comparably less attention and development than other domains of cognition. These include difficulties in representing the intentions and perspectives of others (mentalising), recognising emotions, inferring nuanced social communications such as sarcasm and deceit, accessing social knowledge, and emotion-based decision-making. Founded on distributed neuroanatomical substrates, impairments of these functions have been found to be present and enduring across major sub-groups of acquired brain injury (for review see [1]). The theoretical richness of the social neuroscience revolution has not been matched by the translation of concepts and findings into rehabilitation practice. This article will review the embryonic field of social cognition rehabilitation, categorised into three intervention clusters: a) explicit skills training, b) embodied and affective interventions and c) relational approaches.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87863731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"History of Neurology: Parkinson’s Disease Before James Parkinson","authors":"A. Larner","doi":"10.47795/pqmx5905","DOIUrl":"https://doi.org/10.47795/pqmx5905","url":null,"abstract":"Every neurologist knows that James Parkinson (1755-1824) published An Essay on the Shaking Palsy in 1817. In this work, Parkinson described six personally observed cases, although three were only seen in passing, what Professor Andrew Lees has evocatively termed “street watch methodology”, an experience which may be familiar to many neurologists even today. The eponym of Parkinson’s disease was promoted later in the nineteenth century (1877) by Jean-Martin Charcot [1]. A question long asked is whether Parkinson was describing a new disease in 1817, or whether he was simply the first to crystallise the clinical gestalt which we now recognise as “Parkinson’s disease” (PD).","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85291524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The use of virtual reality in assisting rehabilitation","authors":"M. Grealy, Bilal Nasser","doi":"10.47795/zjai9676","DOIUrl":"https://doi.org/10.47795/zjai9676","url":null,"abstract":"Recent technological advances in the computer and games industries have transformed our homes and workplaces and are now making an impact in clinical settings. Computer-assisted rehabilitation programmes that make use of Virtual Reality are poised to revolutionise how therapy is delivered, but we still know relatively little about the potential benefits of this form of intervention. This review outlines our current knowledge and highlights some of the areas for future research.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"186 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76025082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Generic preference-based measures: how economists measure health benefit","authors":"Chris Sampson","doi":"10.47795/ziwx7131","DOIUrl":"https://doi.org/10.47795/ziwx7131","url":null,"abstract":"Resources are always scarce, but the possible uses of these resources are limitless. This simple observation underlies much of what economists do. It leads to competing demands from different parties and requires individuals and organisations to make choices about their use of scarce resources. The primary purpose of economics is to help us understand how decisions about the distribution of scarce resources are made and to identify optimal decisions. It shouldn’t take too much of an intellectual leap to see how adopting an economist’s perspective might contribute to the improvement of patient care and health outcomes. The process of evaluating health care interventions is well-established, with the randomised controlled trial maintaining its place as the gold standard method. A crucial decision that must be made in figuring out if an intervention works is which indicator should be used. The purpose of the intervention might be to reduce mortality, improve functioning or prevent falls. It could be all three. If the intervention produces an improvement in these indicators it is probably of value – but of what value? How do we value this intervention? And why might we want to?","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86054911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Solomon Carter Fuller (1872-1953) and the Early History of Alzheimer’s Disease","authors":"A. Larner","doi":"10.47795/utwe9625","DOIUrl":"https://doi.org/10.47795/utwe9625","url":null,"abstract":"","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86314675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pes Cavus - Not just a clinical sign. Diagnosis, Aetiology and Management","authors":"T. Ball, M. Butler, S. Parsons","doi":"10.47795/wqcw9805","DOIUrl":"https://doi.org/10.47795/wqcw9805","url":null,"abstract":"Definition Pes cavus is an umbrella term describing a spectrum of foot shapes with a high arch. Pure Pes cavus occurs when the metatarsal bones are plantarflexed relative to the hindfoot – described as ‘forefoot plantaris’ – which increases the height and curvature of the medial longitudinal arch (Figure 1). When the patient weight-bears, the hindfoot is pushed into dorsiflexion by the plantarflexed forefoot (Figure 2). A high arch accompanied by a medially angulated heel is termed pes cavovarus (Figure 3). When this is complicated by foot drop and equinus of the ankle, it is described as pes equinocavovarus. Another variant, pes calcaneovarus, occurs when the primary deformity is excessive ankle and hindfoot dorsiflexion; in order to place the foot flat on the ground, the forefoot plantarflexes, leading to a high arch. On radiographs, a high arch manifests as a Meary’s angle of over 5 degrees – the angle between the long axis of the talus and the first metatarsal in the lateral view (Figure XR 4). The talus and the calcaneum are dorsiflexed, with calcaneal pitch exceeding 30 degrees. The calcaneum appears shortened when in varus. On the dorso-plantar view, supination is seen as a narrow talo-calcaneal angle (Figure XR 5). The wide spectrum of normality leads to controversy over the inclusion of milder variants in the definition of pes cavus. An objective measure of the degree of supination or pronation, the Foot Posture Index (FPI), has been developed and validated. However, while the FPI describes and quantifies foot shape, it does not delineate the normal foot from pes cavus. In practice, what is important is that subtle cases of pes cavus are identified and that potential pathology is considered.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74560115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phenol nerve block for the management of lower limb spasticity","authors":"Moheb Gaid","doi":"10.47795/cwth7183","DOIUrl":"https://doi.org/10.47795/cwth7183","url":null,"abstract":"Spasticity is defined as a motor disorder with failure to inhibit velocity-sensitive stretch reflexes leading to exaggerated muscle resistance. It is a cardinal feature of upper motor neuron lesions and can affect patients with congenital and acquired brain and spinal cord injuries of variable aetiologies (traumatic, vascular, neoplastic, and demyelination). The exact incidence and prevalence of spasticity are unknown. A consensus of experts in Britain believes it to be about 20% of stroke patients and 75% of patients with severe brain injury [1]. Spasticity varies in severity from muscle stiffness to severe, painful, and uncontrollable muscle spasms. Spasticity can be general, involving multiple limbs and trunk muscles, regional, affecting a group of muscles in one or more limbs, or focal, affecting a single muscle. Spasticity can affect the ability to feed and dress oneself, bladder and bowel control, hygiene, and mobility. It also predisposes to complications such as pressure sore formation due to poor seating / laying posture and contracture.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75503412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}