mjl@ jm`@ krkwk ldrst l`lmy@最新文献

{"title":"Antioxidant and Hyperlipidemia Effect of Ganoderma Lucidum Fungus Alcoholic Extract in Male Albino Rats Using Tritonwr 1339","authors":"Husain AL- Obaidy, Saleh M. Rahim, T. Al-Khesraji","doi":"10.32894/kujss.2019.14.2.14","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.14","url":null,"abstract":"The current study aimed at knowing the biological efficacy of Ganoderma lucidum mushroom extract anti-oxidation and induced hyperlipidemic using Triton WR1339 and comparing its efficacy with the simvastatin drug. Study at the Animal House in the Department of biology-Faculty of Science of Kirkuk University for the period from 1/5/2017 to 25/5/2017 used 20 rat male Sprague Dawley type. Distributed to 4 groups of 5 rats per group. The control group was treated with a single dose of the normal salin solution, the second group was treated with a single dose within the Intraperatonal (iP) a dose of 300 mg/kg of body weight. The third group was treated with Triton and was dosed with the alcoholic extract of G. Lucidum with a dose of 30 mg/kg bw/day of body weight by Gavage. The fourth group was treated with Triton and dosed with the simvastatin drug at a dose of 0.3 Kirkuk University Journal /Scientific Studies (KUJSS) Volume 14, Issue 2, June 2019, pp. (232-248) ISSN: 1992-0849 (Print), 2616-6801 (Online) Web Site: www.uokirkuk.edu.iq/kujss E-mail: kujss@uokirkuk.edu.iq, kujss.journal@gmail.com 234 mg/kg body weight. The animals were drugged and the blood was pulled after a period of six days (trial period) showed the results of the biochemical tests that the treatment of rats with Triton material increased morally (p≤0.05) at the total cholesterol level TC, Triglyceride TG, low-density lipoprotein For cholesterol LDL-c, very low density lipoprotein cholesterol VLDL-c, the Athero index and lipid level of the Malondialdhyde MDA. Coupled with the low-density lipoprotein of cholesterol HDL-c, the total capacity of the antioxidant TAC, glutathione GSH and the catalase enzyme CAT compared to a group of control. While the animal dosage of the treatment with Triton and the alcoholic extract of the fungus G.lucidum positive improvement in all the variables mentioned above. The results of this study showed that the fungus extract superior the simvastatin drug at the level of HDL-c as well as at the level of antioxidant balance Oxidation by increasing the level of GSH, TAC and CAT enzyme and reducing MDA fat peroxide. Fungus can be adopted as an effective antioxidant and antihypertensive agent","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42901295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In- Vitro Study of Antibacterial Properties and Phytochemical Contents of Coriander Seeds Against Five Bacteria.","authors":"Arjan Zeynel, U. Abbas","doi":"10.32894/kujss.2019.14.2.1","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.1","url":null,"abstract":"In an effort to highlight the role of digestion and maceration methods to determine the strength of antibacterial effect and phytochemical elements of coriander seeds aqueous and methanolic extracts. Five concentrations (20, 40, 80, 160 and 320 mg/ml) of four extracts (aqueous by maceration, aqueous by digestion, methanolic by maceration and methanolic by digestion) were utilized against five clinically isolated bacteria (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aerogenosa and Acenitobacter baumani), and compared with ciprofloxacin and cefotaxime discs as control. Agar well diffusion technique was employed to clarify the antibacterial activity of the extracts' concentrations relaying on quantifying the diameter of inhibition zone (IZ) in millimeter. The bioactive chemical compounds of four extracts were specified by means of conventional systems. In the main, all extracts inhibited the growth of every bacterial species starting from (80) mg/ml concentration, forming IZs' with various measurements that their expansion was drawing upon the rising of extracts' concentrations. The IZs that proceeded from (160, 320) mg/ml concentrations were larger than that come out from cefotaxime. The maceration extracts declared their embracement of alkaloids, and their impact were vigorous compared with the extracts of digestion which marked by comprising the tannins and flavonoids in aqueous and methanolic extracts one by one. The most susceptible bacterium to ethanolic extracts was S. aureus. It could be benefiting from coriander seeds for treatment of bacterial infections through extraction the Kirkuk University Journal /Scientific Studies (KUJSS) Volume 14, Issue 2, June 2019 , pp. (1-18) ISSN: 1992-0849 (Print), 2616-6801 (Online) Web Site: www.uokirkuk.edu.iq/kujss E. mail: kujss@uokirkuk.edu.iq, kujss.journal@gmail.com 2 best active phytoconstituents by using both of suitable extraction technique and solvents together.","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47543343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial Contamination and its Response to Antibiotics and Disinfectants Used in the Children's Hospital in Kirkuk","authors":"Ahmed Mohamed, Najdat Mahde","doi":"10.32894/kujss.2019.14.2.11","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.11","url":null,"abstract":"The study included, the collection of (250) swabs which involve (180) samples from general children's Hospital environment and various isolation sources, In addition to (70) smear from the hands and noses of medical staffs and workers, Using sterile cotton swabs and then planted on the Cultuer media (MacConkey's agar and Blood agar). The results showed that (126) smears and in a ratio of (50.4%) was positive for the bacterial isolations which contribute the followings:Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli , Enterobacter cloacae, Proteus mirabilis, Klebsiella pneumonia, Pseudomonas aeruginosa, with variant isolation ratios. It high rate of contamination (73.33%), was from Hospitals environment compared to (71%) of contamination from the hands of medical staffs. Resistany agaings antibiotic was praceddon (12) antibiotics and the results showed that most of the isolates are resistant For anti-beta-lactam groups the rate was (81.74%), the followings antibiotics vancomycin, imipenem, amikacin reveal high efficucy against the isolated Staph.aureus , Staph.epidermidis , Esch.col, Prot.mirabilis , pathogens Ps.aeruginosa with reduction resistany reach to (23.80), (24.60), (36.50) respectively. The Minmam inhibitory concentration was detected using virkon, Opizil, Strillium, and bleach, ethyl alcohol, Optisal ® N was found to passing a better inhibition effect on the elected isolates, followed by an Virkon, compared with the disinfectant of sodium hyper chlorate (minor), The Kirkuk University Journal /Scientific Studies (KUJSS) Volume 14, Issue 2, June 2018 , pp. (175-192) ISSN: 1992-0849 (Print), 2616-6801 (Online) Web Site: www.uokirkuk.edu.iq/kujss E. mail: kujss@uokirkuk.edu.iq, kujss.journal@gmail.com 177 following value MIC walues were obtained (0.25-0.0625, 0.5-0.078, 1.25-0.156%) moreover, the antiseptics used for cleaning the hands showed that, a streillium antiseptics is wosh high bacterial inhibition impact than the ethyl alcohol, as the lower inhibitory values of the streillium antiseptics ranged from (80-50%) while the ethyl alcohol disinfectant was the least efficient as it reached its inhibitory values minimum (80-60).","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46319830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligent Control of Permanent Magnet Synchronous Generator Based Wind Energy Conversion System","authors":"M. Mohammed","doi":"10.32894/kujss.2019.14.2.3","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.3","url":null,"abstract":"Abstract In this work new maximum power extracted architecture is proposed for wind turbine generator. Adaptive network based fuzzy inference system (ANFIS) is used to precisely estimate the rotor angle and speed which is necessary for vector control in order to forces the generator to track maximum power using variable speed operation generator. In this algorithm the separate control of the torque from the flux make the control of a generator operation with variable speed more efficient. The ANFIS network is trained off line from the normal operation of the permanent magnet generator.","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49061035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Theory of Mitigate Temperature Effect on the Equilibrium Point in Vertical Cavity Surface Emitting Lasers","authors":"H. Hisham","doi":"10.32894/kujss.2019.14.2.4","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.4","url":null,"abstract":"Abstract This paper presents a way to mitigate the influence of temperature effects on the equilibrium point (Q-point) of vertical cavity surface emitting lasers (VCSELs) by investigating the effect of laser injection current (Iinj) and dc-bias level (Ibias) numerically using MATHCAD software. Results show that, by changing temperature 50 o C (i.e. from 10 to 60) with Iinj = 3Ith and Ibias = 0, the photons density (P(t)) has decreased from 1.636 × 10 cm to 0.733 × 10 cm, the carrier density (N(t)) has increased from 2.367 × 10 cm to 2.669 × 10 cm and the laser output power (Pout) has decreased from the 2.366 mW to the 1.025 mW. In contrast, by increasing the Iinj from 3Ith to 5Ith and the Ibias from 0 to 1.5Ith, the rate of the decreasing in the P(t) and in the Pout have reduced more than 25%.","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43982224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Thermodynamic and Kinetic Adsorption of Azo Dyes on Different Adsorbent Surfaces","authors":"F. Al-Abady, Nashwan O. Tapabashi, Afnan Bahjat","doi":"10.32894/kujss.2019.14.2.16","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.16","url":null,"abstract":"The kinetics and thermodynamics of the removal of Alzarin yellow and Congo red dyes from their aqueous solutions using local clay taken from Shoraw region northwest of the province of Kirkuk Iraq as well as bentonite and activated charcoal as adsorbents was held, using UVvisible spectroscopy to follow the adsorption process. The equilibrium time of the adsorption process was determined and found that it reached a state of equilibrium in a period of time between 70-50 min, in the case of adsorption of the dyes on the activated charcoal and bentonite surfaces and 70-60 min, when using the clay. The results indicated that the best weight of the adsorbent surfaces is (0.1gm). Adsorption was studied in the natural pH of the basic dyes, as well as in the acidic and neutral pH. Isotherm (Freundlich and Langmuir) was used, and it was found that the best isotherm is Freundlich. Adsorption efficiency was calculated in the range of 15-65 o C of temperature. It was found that the adsorption efficiency decreased by increasing the temperature in the case of alizarin yellow dye adsorption on the three surfaces. Whereas the adsorption efficiency of Congo red on the clay surface decreased by increasing the temperature and this indicates that the reaction is exothermic. It has been found that the efficiency of adsorption is increased by increasing the temperature in the case of adsorption of Congo red dye on activated charcoal and bentonite surfaces and this indicates that the reaction is endothermic. The values of the thermodynamic parameters of the adsorption process and the adsorption kinetics study were calculated and found that the adsorption follows the pseudosecond order equation. Keyword: adsorption; kinetics and thermodynamic study , Azo dyes. DOI: http://doi.org/10.32894/kujss.2019.14.2.16 Kirkuk University Journal /Scientific Studies (KUJSS) Volume 14, Issue 2, June 2019 , pp. (273-296) ISSN: 1992-0849 (Print), 2616-6801 (Online) Web Site: www.uokirkuk.edu.iq/kujss E-mail: kujss@uokirkuk.edu.iq, kujss.journal@gmail.com 386 1 . ةمدقملا : ثومتلا دعي اينم صػمختلاو ايتلا زا ةػيفيك ةفرعم بمطتت يتلاو يلاحلا تقولا يف فاسنلاا وجاوت يتلا ؿكاشملا ـىأ فم ايتدايز يف فاسنلأا وبعمي يذػلا حضاولا رودػلا ببسب ايتروطخ ـقافتػت ةمكشملا هذىو [1] . اينمو ثومتمل عاونا ةدع ؾانى ذلاو ةػبرتلا ثومت ؿمشي يذػلاو يئيبلا ثومتلا ي ي ةيئايميكلا داوملا ـكا رت وببس [2] ، ؿصحي يذلا ءاوػيلا ثومت ىلا ةفاضا تاسسؤملا فم يتأػي يحصلا ؼرصلا هاػيمو ةيفوجلا هاػيملا ثومتو ةػماسلا ةرياطتملا تاػبكرملاو تاباغلا ؽا رتحلأ ةجيتن ةمئاسلا ةيعانصلا تاػيافنلا ؼذقت يتلا ةيراػجتلاو ةماعلا [3] . ةيعانصلا غابصلأا فا ،يئاملا ـاظنمل تاثومملا ـىأ فم دعت ـاع يفف ،يئاملا ـاظنمل ةثومملاو ـلاعلا يف ةيئايميكلا تاعانصلا يف ةمدختسملا عيماجملا رثكاو ـىا فم ةدحاو ييف 1990 فاك جاتنلإا ( فم رثكا ؿزغلا غابصا فػم يونسلا 8 غيرفت ـتيو )فط فويمم 10% ةمئاس تايافنك اػينم [4] . فكلو ،ءاملاب بوذت لا اينم ـسقف ءاملا يف ايينابوذ ةجرد يف )ةيعانصلا غابصلأا ـىا ىدحا(وزلآا غابصا توافتت دػيدعلا فأ ظحولو فابوذلا ؿيمق رخلاا ـسقلاو ،ىرخا داومو ","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48752189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shales Geochemistry within Kolosh Formation (Paleocene – Early Eocene ) in Dokan Region – Northeastern Iraq; Implications for Provenance, Paleoweathering and Tectonic Setting","authors":"Abbas Raza Ali, Torhan M. H. Al-Mufti, Mustafa Ahmed","doi":"10.32894/kujss.2019.14.2.8","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.8","url":null,"abstract":"The study is carried out on twenty shale samples that were collected from the Kolosh Formation (Paleocene – Early Eocene) within the Dokan area at northeastern part of Iraq. The samples were subjected to laboratory studies including chemical analyses for origin rock characterizing source rock composition, paleo-weathering conditions and tectonic. The origin rock compositions were evaluated mainly based on Al2O3/TiO2, TiO2/Zr ratios and a TiO2 and Al2O3bivariate. The result suggest predominantly intermediate igneous source rock of the Kolosh Formation shale’s. The bivariate plot, of (K2O/Na2O) and (SiO2), (MgO+Fe2O3 %) and (TiO2%), as well as the refashion ships based on the elemental components (Co ,Th, Sc, Zr, La) were used to reveal tectonic setting of the depositional basin. All Kolosh Formation shale’s samples were in Oceanic Island Arc. CIA values, bivariate plot of (SiO2%) and (Al2O3+Na2O3+K2O)% and ) (Al2O3CaO+Na2OK2O) % compositional space of the shale samples were utilized to infer the chemical maturity and the pale weathering conditions of the Formation. The results shows that Kolosh shale samples represent lower degree of chemical weathering of origine rock which imply semi-arid climatic conditions. Keywards: Kolosh, Shale, Provenance, Tectonic, Dokan region. DOI: http://doi.org/10.32894/kujss.2019.14.2.8 Kirkuk University Journal /Scientific Studies (KUJSS) Volume 14, Issue 2, June 2019, pp. (125-144) ISSN: 1992-0849 (Print), 2616-6801 (Online) Web Site: www.uokirkuk.edu.iq/kujss E-mail: kujss@uokirkuk.edu.iq, kujss.journal@gamail.com 527 1 . ةمدقملا : شولوك نيوكت فصو لولأ ( يجذومنلا عطقملا دنع ةرم type section شولوك ةقطنم يف ) لبق نم قجنسيوك لامش ( Dunnigton ) [1] ( ةيتاتف تابسرت شولوك نيوكت لثمي . Clastic sediments ،ايكمس يف ةرياغتم ةيقابط تاعباتتل ) و نكاد رضخا نول تاذ ةيممر روخص نم ةمغانتمو ةرركتم يىو يدامر نول وذ اينم ضعبلا ايقابط ةمخادتم ( Interbedded ) ا نوملا وذ لفطلا روخص عم يدامرلا نكادلا و ( حفصتملا دوـسلاا black fissile shale لكشب وأ ) ( ةينيرغلا روخصلا نم تادحولا ضعب عم تاسدع siltstone ( ةيريجلاو ) limestone تاكممدملا نم ليمقو ) ( Conglomerate ) [2] لثمي فل ةيبيسرتلا ةرودلا تانيوكت ىدحا نيثحابلا نم ريبك ددع ءا رآ قافتابو شولوك نيوكت ةرت نيسويلابلا لا نيسويلأا ركبم ( Paleocene – Early Eocene ) [3,4] ي ن فشك نيوكتلا ةدع يف عساو لكشب رشتنيو قطانم نم لامش قرش لامشو ةيط يفو نايزابو كنابو ناخيشو ةولاقش لثم ،قا رعلا كوىد يف ريخيب ، قجنسيوكو نا رجىو .ىرخأ قطانمو ناخيدنبردو ناكود يتقطنمو )شولوك ةقطنم يف( ( يممرلا رجحلا روخص ىمع ةريثك تاسا رد تدمتعا Sandstone ،روخصلا ةيردصم زييمتو ديدحت يف عساو لكشبو ) لفطلا روخص نا ريغ يممرلا رجحلاب ةنراقم ةيمىا اذ دعت سا رد يف لصلاا ة لدعم سكعي ونلا كلذو يف رصانعلا دجاوت اذىو ةيضرلاا ةرشقلا بيكرت و ةسناجتملا وتعيبط ببسب وتيذافن ،بيسرتلا ةيممع دعبام ةميمقلا روخص ةيئايمكويج دعت اذيل ةيئايمكويج نم لضفا لفطلا ردصملا ةسا رد يف ىرخلاا روخصلا [5] . ةيوناثلاو ةسيئرلا رصانعلا ةيئايمكويج تتبٌثا خصل اولا ايتيمىا لفطلا رو ردصملا ةسا رد يف ةعس ا خانملاو ةيبوسرلا ضاوحلاا نم ددعل ميدقل 9] [6 راشا دقو [10,11] ( ","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45361201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of The Effectiveness of Buttermilk 1n Reducing Hyperlipidemia And The Effectiveness of Liver Enzymes in Healthy Rats And Experimental Hyperlipidemia","authors":"M. Jasim, S. Oleiwi, Manal S. Mahdi","doi":"10.32894/kujss.2019.14.2.10","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.10","url":null,"abstract":"This study was designed to determine the impact of Buttermilk on blood total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C) and the efficacy of liver enzymes ALT, AST and ALP, healthy and hypercholesterol experimental Sprague-Dawley rats were used as a model to the hypercholesterolemic group (41.23) IU /L. it was concluded that Buttermilk played a positive role to improve lipid profile in hypercholesterol rats.","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48883689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectrophotometric Determination of Promethazine Hydrochloride in Pharmaceutical Formulation by Oxidative Coupling.","authors":"M. Abdulaziz, M. Bakir, A. Shareef","doi":"10.32894/kujss.2019.14.2.7","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.7","url":null,"abstract":"A simple, rapid and sensitive spectrophotometric method for determination of trace amounts of Promethazine hydrochloric in aqueous solution is described. The method is based on using the oxidative coupling reaction of promethazine hydrochloride with 4-amino 2-hydroxy benzoate reagent in acid medium in the presence of N-bromo Succinimide to produce an intense green colour, water soluble, product which exhibit maximum absorbance at 605.5 nm. Beer's law is obeyed over concentration range of (2-32μg/m1), with a molar absorptivity 7540.68 l/mol.cm, Sandel index of 0.04255 μg / .The average recovery is 100.7703 %, relative standard deviation of 0.3101 to 0.8474 % and D.L of 0.40825 μg/ml.","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42976660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectrophotometric Determination of Atenolol Using Indigo Carmine Dye","authors":"B. Saleem","doi":"10.32894/kujss.2019.14.2.2","DOIUrl":"https://doi.org/10.32894/kujss.2019.14.2.2","url":null,"abstract":"A simple, rapid, accurate and precise spectrophotometric method is proposed for the determination of atenolol in both pure form and in its pharmaceutical formulation. The method is based on the oxidation of atenolol with chromate in acidic medium of 1N H2SO4, the residual amount of oxidizing agent is then reacted with indigo carmine dye in the presence of oxalate as a catalyst, the increase in the absorbance of the dye, which is proportional to the amount of the determinants atenolol is then measured at 610 nm. Beer's law is obeyed in the concentration range of 30-1500 μg/25 ml with a molar absorptivity of 0.73×10 4 l.mol -1 .cm -1 , Sandell's sensitivity index of 0.364 μg.cm -2 , and a relative standard deviation of ± 0.263 to ± 0.376% depending on the concentration level. The limit of detection (LOD) and limit of quantification (LOQ) are 0.3259 and 1.0863 μg ml −1 , respectively. The proposed method has been applied successfully to the determination of atenolol in pure and pharmaceutical preparation.","PeriodicalId":34247,"journal":{"name":"mjl@ jm`@ krkwk ldrst l`lmy@","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44876955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}