Annals of Clinical Microbiology最新文献_第3页

Multicenter Study on the Molecular Epidemiology of Intestinal Protozoan Parasites in Korea 韩国肠道原生动物寄生虫分子流行病学多中心研究

Annals of Clinical Microbiology Pub Date : 2023-09-20 DOI: 10.5145/acm.2023.26.3.4

Changseung Liu, YeJin Oh, Young Jin Ko, Mi Hyun Bae, Jung-Hyun Byun, Eun Jeong Won

{"title":"Multicenter Study on the Molecular Epidemiology of Intestinal Protozoan Parasites in Korea","authors":"Changseung Liu, YeJin Oh, Young Jin Ko, Mi Hyun Bae, Jung-Hyun Byun, Eun Jeong Won","doi":"10.5145/acm.2023.26.3.4","DOIUrl":"https://doi.org/10.5145/acm.2023.26.3.4","url":null,"abstract":"Background: Intestinal protozoa are potential diarrhea-causing pathogens and monitored worldwide. The Korea Centers for Disease Control and Prevention has also been monitoring intestinal protozoa causing diarrhea for many years. Recently, the overall protozoa detection rate has decreased to less than 1%, but whether protozoa infection causing diarrhea has declined or is being underestimated has not been studied. This study aimed to investigate the molecular epidemiology of intestinal protozoan pathogens in stool samples collected from multiple Korean centers. Methods: Stool samples were collected from five university hospitals and a commercial laboratory. Direct smear and trichrome staining were performed on all samples. The presence of Cryptosporidium parvum, Giardia lamblia, Entamoeba histolytica, Cyclospora cayetanensis, Dientamoeba fragilis, and Blastocystis hominis were detected using Allplex™ Gastrointestinal Parasite Assays (Seegene Inc., Korea). Microsporidia species and Kudoa septempunctata were detected using PowerChek™ Microsporidia Multiplex and Kudoa Real-time PCR kits (Kogene Biotech, Korea), respectively. Results: The collected samples included 279 diarrheal and 51 non-diarrheal samples. Among the 279 diarrheal samples, nine samples [B. hominis (n=7), C. parvum (n=1), and Microporidia species (n=1)] were positive, but there were no positive samples for K. septempunctata. We could not detect any protozoa by direct smear and trichrome staining. Among the 51 nondiarrheal samples, 10 (19.6%) samples were positive for B. hominis, but no other protozoa were observed. Conclusion: This multicenter study showed that the detection rate of intestinal protozoa is currently low in diarrheal samples from Korea. However, B. hominis was frequently detected in non-diarrheal samples, indicating their low pathogenicity.","PeriodicalId":34065,"journal":{"name":"Annals of Clinical Microbiology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136378333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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False Positive Cases in Automated Blood Culture Systems Due to Hyperleukocytosis 白血球过多导致的自动血液培养系统假阳性病例

Annals of Clinical Microbiology Pub Date : 2023-06-20 DOI: 10.5145/acm.2023.26.2.2

Do-Hoon Kim, N. Ryoo

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Risk Factors Associated With Colistin-Resistant Acinetobacter baumannii Infection 耐粘菌素鲍曼不动杆菌感染的相关危险因素

Annals of Clinical Microbiology Pub Date : 2023-06-20 DOI: 10.5145/acm.2023.26.2.1

Hae-Sun Chung, C. Hahm, Miae Lee

{"title":"Risk Factors Associated With Colistin-Resistant Acinetobacter baumannii Infection","authors":"Hae-Sun Chung, C. Hahm, Miae Lee","doi":"10.5145/acm.2023.26.2.1","DOIUrl":"https://doi.org/10.5145/acm.2023.26.2.1","url":null,"abstract":"Acinetobacter baumannii is an important cause of healthcare-associated infections and is resistant to almost all antimicrobial agents, with strains recently reported to be resistant to colsitin. In this study, we aimed to identify the risk factors associated with colistin-resistant A. baumannii infections by comparing colistin-resistant and -susceptible A. baumannii isolates. We retrospectively reviewed the medical records of 51 and 100 cases in which colistinresistant and -susceptible A. baumannii were isolated, respectively. Univariate analysis showed that compared with patients with colistin-sensitive infections, patients with colistinresistant A. baumanni infections had a combined pulmonary disease (P = 0.017), were admitted to intensive care unit (P = 0.020), and had prior mechanical ventilation (P = 0.003), tracheostomy (P = 0.043), percutaneous drainage (P = 0.070), hemodialysis (P = 0.002); use of colistin (P = 0.000), carbapenem (P = 0.000), and teicoplanin (P = 0.004); and co-infection (P = 0.035). Multivariate analysis indicated that eight variables were related to the likelihood of colistin-resistant A. baumanni infections: use of teicoplanin (Odds ratio [OR]: 3.140, 95% confidence interval [CI]: 0.529–18.650), prior hemodialysis (OR: 2.722, 95% CI: 0.851–8.709), combined pulmonary disease (OR: 2.286, 95% CI: 0.998–5.283), prior use of carbapenem (OR: 0.199, 95% CI: 0.863–5.603), co-infection (OR: 1.706, 95% CI: 0.746–3.898), prior mechanical ventilation (OR: 1.614, 95% CI, 0.684–3.809), intensive care unit admission (OR: 1.387, 95% CI: 0.560–3.435), and prior tracheostomy (OR: 1.102, 95% CI: 0.344–3.527); however, no statistical differences were observed. Although colistin use could not be proven in multivariate analysis, the possibility of being a risk factor cannot be ruled out.","PeriodicalId":34065,"journal":{"name":"Annals of Clinical Microbiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41646857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Syndromic Testing for Sexually Transmitted Infection: Current and Future Demand 性传播感染的综合征检测:当前和未来的需求

Annals of Clinical Microbiology Pub Date : 2023-01-01 DOI: 10.5145/acm.2023.26.1.1

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Evaluation of Two Commercial Kits for Rapid Pathogen Identification Directly From Positive Blood Cultures by Matrix-Associated Laser Desorption/Ionization Time-of-Flight Mass Spectrometry 用基质相关激光解吸/电离飞行时间质谱法直接从阳性血培养物中快速鉴定病原体的两种商用试剂盒的评价

Annals of Clinical Microbiology Pub Date : 2023-01-01 DOI: 10.5145/acm.2023.26.1.3

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Epidemiology and Subtype Distribution of Blastocystis Among Asymptomatic Volunteers in South Korea: A Multicenter Study 韩国无症状志愿者中囊虫的流行病学和亚型分布:一项多中心研究

Annals of Clinical Microbiology Pub Date : 2023-01-01 DOI: 10.5145/acm.2023.26.1.2

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Laboratory Indicators for Convalescence in SARS-CoV-2 Positive Cases with High Ct Value 高Ct值SARS-CoV-2阳性患者恢复期实验室指标分析

Annals of Clinical Microbiology Pub Date : 2022-01-01 DOI: 10.5145/acm.2022.25.3.6

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Clinical and Microbiological Risk Factors for Severe Clostridioides difficile Infections 严重艰难梭菌感染的临床和微生物危险因素

Annals of Clinical Microbiology Pub Date : 2022-01-01 DOI: 10.5145/acm.2022.25.1.3

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Antiviral Resistance in Human Cytomegalovirus Due to UL54 Mutations Without UL97 Mutations 未发生UL97突变的人巨细胞病毒UL54突变对抗病毒药物的耐药性

Annals of Clinical Microbiology Pub Date : 2022-01-01 DOI: 10.5145/acm.2022.25.2.2

引用次数: 1

Clinical and Microbiological Risk Factors for Community-Associated Clostridioides difficile Infections 社区相关艰难梭菌感染的临床和微生物危险因素

Annals of Clinical Microbiology Pub Date : 2022-01-01 DOI: 10.5145/acm.2022.25.2.3

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