Southern Clinics of Istanbul Eurasia最新文献

{"title":"Clinical Significance of the Psoas Muscle Index in Patients with Locally Advanced Gastric Cancer Receiving Perioperative Chemotherapy","authors":"Akif Doğan","doi":"10.14744/scie.2023.94695","DOIUrl":"https://doi.org/10.14744/scie.2023.94695","url":null,"abstract":"Objective: The psoas muscle index (PMI) obtained with a single muscle measurement on routine computed tomography (CT) performed for staging in locally advanced gastric cancer (LAGC) is helpful in predicting whole-body sarcopenia. The objective of this trial was to determine the relationship between PMI and overall survival (OS) and disease-free survival (DFS). Methods: This retrospective cohort was conducted with 122 patients with LAGC who underwent perioperative chemotherapy and curative surgery in our center between January 2015 and December 2021. PMI and psoas muscle density were calculated at the L3 vertebra level using routine CT performed for staging after the LAGC diagnosis, and its relationship with OS and DFS was examined. Results: Twenty-nine of 122 patients were women. FLOT was the most common chemotherapy regimen and total gastrectomy was performed most frequently. The patients were divided into two groups according to the PMI values. OS and DFS were unachievable in the high PMI group, while OS and PFS were determined as 19 and 16 months, respectively, in the low PMI group. There was a statistically significant difference between the high and low PMI groups in terms of the two survival parameters (p=0.03 and p=0.001, respectively). Conclusion: PMI measured on CT performed for staging in patients diagnosed with LAGC is an important and practical method in predicting the prognosis of the disease. ABSTRACT","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importance of Diastolic Dysfunction and Nt-ProBNP Measurement for Identification of Volume Load in Predialysis Chronic Renal Failure Patients","authors":"B. Boyuk","doi":"10.14744/scie.2023.70845","DOIUrl":"https://doi.org/10.14744/scie.2023.70845","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67342830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Fasting or Post-prandial Blood Glucose Monitoring be used as a Method in the Diagnosis of Gestational Diabetes and Predicting its Complications in Patients who Refuse OGTT?","authors":"Gulchin Babayeva","doi":"10.14744/scie.2023.95777","DOIUrl":"https://doi.org/10.14744/scie.2023.95777","url":null,"abstract":"Objective: Gestational diabetes mellitus (GDM) is one of the most common metabolic diseases in pregnancy. Negative news in the media has made the GDM test controversial among patients. We aimed to investigate the usability of fasting blood glucose (FG), HgA1c, and post-prandial 2nd-h blood glucose (PG) instead of an oral glucose tolerance test (OGTT) in the diagnosis of GDM and predict its possible complications. Methods: This retrospective cohort study was conducted among patients admitted to a private hospital in Istanbul between December 2020 and July 2022. In our clinic, patients who refuse OGTT are routinely asked for FG and PG after a normal meal. We also evaluate the HgA1c value. Data of 374 patients were obtained and 150 patients were included in the study after exclusion criteria. Women aged 24–28 weeks who refused OGTT were considered the study group. Patients who accepted OGTT were diagnosed with diabetes before, and FG and PG results could not be reached and were excluded from the study. In addition, patients with a body mass index above 35 were not included in the study. Polyhydramnios and macrosomia, which are common diabetes complications, were evaluated during the follow-up of patients, and these conditions were associated with FG and PG. Results: Due to our results, it was determined that FG was weak and PG was moderately successful in estimating the emergence of abnormal fetal characteristics in pregnant women. When the threshold value of FG was taken as 94 mg/dL, the sensitivity was 43%, and the specificity was 8.8%. When the threshold value of post-prandial blood glucose was taken as 143.5 mg/dL, the sensitivity was 64%, and the specificity was 14% (p<0.05). The HgA1c values of the patients did not show a significant difference between the patients who were diagnosed with polyhydramnios and macrosomia and those who did not. Conclusion: The OGTT is still the most valuable test for the diagnosis of GDM. Women who refuse to do OGTT, especially PG, may be valuable in terms of GDM and its complications. For these patients, more study is needed. ABSTRACT","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Shock Index as a Predictor of Mortality in Patients with Pulmonary Embolism","authors":"İzzet Ustaalioğlu","doi":"10.14744/scie.2023.26096","DOIUrl":"https://doi.org/10.14744/scie.2023.26096","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67342127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of “online therapy” and “telepsychiatry” topics in the Covid-19 Pandemic based on Google Trends Data","authors":"M. B. Gürcan","doi":"10.14744/scie.2023.68725","DOIUrl":"https://doi.org/10.14744/scie.2023.68725","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67342756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can we Provide Effective Glycemic Control in Intensive Care Unit? Point Prevalence Study","authors":"Yeliz Bilir","doi":"10.14744/scie.2023.47568","DOIUrl":"https://doi.org/10.14744/scie.2023.47568","url":null,"abstract":"Objective: Blood glucose dysregulation is independently associated with mortality and morbidity in critically ill patients. However, it is difficult to keep glycemic control at targeted levels in diabetic and non-diabetic patients in intensive care units (ICU). A point prevalence study was planned to evaluate glycemic control in patients treated in the tertiary ICU. Ethics committee approval was obtained before starting the study. Methods: The demographic data of the patients, their characteristics at the time of admission, intensive care follow-up and treatment, the nutrition method, and the parameters related to glycemic control were recorded. Results: On the study day, a total of 107 patients, 35 of whom were COVID (C-ICU) and 72 were in the non-Covid ICU (NC-ICU), were included in the study. 47.6% of the patients were male and 29.9% had a diagnosis of diabetes mellitus (DM). The mean blood glucose value of the patients was measured as 158 mg/dL and glycemic dysregulation (4.7% hypoglycemia and 25.2% hyperglycemia) was detected in 29.9% of all patients. Blood glucose levels were unregulated in 28.6% (n=10) of the patients in C-ICU and 30.5% (n=22) patients in NC-ICU. The patients with regulated blood glucose were similar between the two groups (p=0.510). A statistically significant correlation was found between the patients’ unregulated blood glucose levels and the presence of DM (p=0.05). Conclusion: The idea that a certain glucose target may not always be optimal for all patients and that individualized glucose control is currently being discussed. We believe that blood glucose algorithms are necessary in ICUs without putting patients into hypoglycemia or hyperglycemia in routine follow-up. ABSTRACT","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Impact of Maternal Subclinical Hypothyroidism on First-trimester Screening Results","authors":"Aslı Tuğçe Delipınar","doi":"10.14744/scie.2023.81489","DOIUrl":"https://doi.org/10.14744/scie.2023.81489","url":null,"abstract":"Objective: Subclinical hypothyroidism is the most frequent thyroid dysfunction in pregnancy with an incidence of 2–5% which can easily be overlooked due to the absence of clinical symptoms. Studies have shown that thyroid hormones could alter the level of free beta-hu-man chorionic gonadotropin ( β -hCG) and pregnancy-associated plasma protein-A (PAPP-A) released from the placenta during early pregnancy. Since these two serum markers are the two of the parameters used in the first-trimester combined screening, we hypothesized that distorted risk calculation results could be obtained from pregnant women with subclinical hypothyroidism. Methods: We conducted a prospective and cohort study at a tertiary university hospital in northwest Turkey between February 2018 and June 2018, involving 250 pregnant women in their first trimester who were seeking care at the obstetrics outpatient clinic. After evaluation of thyroid functions, first-trimester screening was performed in all 250 singleton pregnancies with fetuses at 11+0 to 13+6 gestational weeks. Thyroid-stimulating hormone (TSH) values above 2,5 mIU/L were considered high. The correlation between the results and parameters of the first-trimester combined screening and thyroid hormone values was examined. Results: Among the participants, after analyzing the fT4 values, all 35 pregnant women with high TSH values were diagnosed with subclinical hypothyroidism. We observed a statistically weak negative correlation between TSH and β -HCG, which was expected given the similarities in their alpha subunits. There was no statistically significant correlation between TSH and PAPP-A values, combined risk scores, and age risk scores of first-trimester screening. As a matter of course, combined risk scores of first-trimester screening were found to be statistically lower in younger mothers. Conclusion: Pregnant women with normal thyroid functions and subclinical hypothyroidism were investigated for alterations in first-trimester screening parameters and risk scores. As a result, no statistically significant correlation was found between subclinical hypothyroidism and first-trimester screening.","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parents' Attitudes to Vaccination","authors":"A. Karaaslan","doi":"10.14744/scie.2022.14890","DOIUrl":"https://doi.org/10.14744/scie.2022.14890","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67338463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of upper extremity function and exercise capacity after Pancoast tumor surgery","authors":"T. Dogruyol","doi":"10.14744/scie.2022.46793","DOIUrl":"https://doi.org/10.14744/scie.2022.46793","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67339466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of anxiety, depression and insomnia levels of healthcare professionals after inactive COVID-19 vaccination (CoronaVac)","authors":"S. Doğruyol","doi":"10.14744/scie.2022.65902","DOIUrl":"https://doi.org/10.14744/scie.2022.65902","url":null,"abstract":"Objective: The aim of this study was to examine changes in the levels of depression, anxiety, and insomnia after inactive COVID-19 vaccination among healthcare professionals working actively during the COVID-19 pandemic. Methods: This cross-sectional study was conducted from January 1, 2021, to June 30, 2021, using an online survey across frontline healthcare professionals in Turkey. The Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) scale were used to evaluate the mental health of the participants, and the Insomnia Severity Index-7 (ISI-7) was used to evaluate their sleep problems. The data obtained from two different periods, pre-vaccination and post-vaccination, were examined. Results: The study included 416 healthcare professionals. The frequency of depression, anxiety, and insomnia was 27.9%, 31.5%, and 41.1%, respectively, in the pre-vaccination period, and there was a decrease in these rates (22.8%, 21.9%, and 34.1%, respectively) in the post-vaccination period. The differences between the two periods were also statistically significant for the PHQ-9 (p=0.000), GAD-7 (p=0.002), and ISI-7 (p=0.038) scores. We determined that the presence of long weekly working hours, being female, living alone, and presence of psychiatric disease were effective in the development of depression and anxiety. Conclusion: Among frontline healthcare professionals, depression, anxiety, and insomnia symptoms and the frequency of the diagnosis of these clinical conditions increased due to the COVID-19 pandemic. However, after the start of the immunization process, the frequency of these mental disorders and the anxiety levels of the healthcare professionals significantly decreased. (English) [ FROM AUTHOR] Amaç: COVID-19 pandemi sürecinde ön saflarda görev yapan sağlık çalışanlarının inaktif COVID-19 aşısı sonrasındaki depresyon, anksiyete ve insomnia düzeylerindeki değişimleri incelemek. Gereç ve Yöntem: Bu kesitsel çalışma, 1 Ocak--30 Haziran 2021 tarihleri arasında Türkiye'de ön saflarda yer alan sağlık profesyonellerini değerlendirmek için çevrimiçi bir anket kullanılarak yürütülmüştür. Katılımcıların mental sağlığını değerlendirmek için Patient Health Questionnaire- 9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7) ölçekleri kullanıldı. Uyku problemlerini değerlendirmek için Insomnia Severity Index-7 (ISI-7) kullanıldı. Çalışmada aşılama öncesi (AÖ) ve sonrası (AS) olmak üzere iki ayrı döneme dair veriler incelendi. Bulgular: Çalışmaya 416 sağlık çalışanı dahil edildi. AÖ dönemde depresyon, anksiyete ve insomnia sıklığı sırasıyla;%27.9, %31.5 ve %41.1 şeklindeydi. Bu oranlarda AS dönemde azalma olup;%22.8, %21.9 ve %34.1 şeklinde olduğu görüldü. Dönemler arasındaki bu farklar PHQ-9 (p=0.000), GAD-7 (p=0.002) ve ISI-7 (p=0.038) için istatistiksel olarak da anlamlıydı. Çalışmamızda yüksek haftalık çalışma saatleri, kadın cinsiyet, tek başına yaşam ve psikiyatrik hastalık varlığı faktörlerinin depresyon ve anksiyete gelişiminde ","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67340741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}