Southern Clinics of Istanbul Eurasia最新文献

{"title":"The Impact of Multidisciplinary Approach on Survival in Esophageal Cancer","authors":"Mehmet Mustafa Altıntaş","doi":"10.14744/scie.2023.98958","DOIUrl":"https://doi.org/10.14744/scie.2023.98958","url":null,"abstract":"Objective: Esophageal cancer, one of the most aggressive gastrointestinal malignancies, is the eighth-most common cancer in the world and the sixth among cancer-related deaths in men. In our study, we aimed to show the survival effect of the multidisciplinary approach in the treatment of esophageal cancer. Methods: The records of 103 patients who were diagnosed with esophageal cancer pathologically by endoscopy and underwent curative resection between January 2010 and December 2020 were reviewed retrospectively. The patients were evaluated in the multidisciplinary tumor council and appropriate treatment (neoadjuvant therapy+surgery or only surgery) was planned for each patient according to the TNM stage.T1N0M0 and T2N0M0 patients underwent direct surgery, T2-T3 and those who were considered to be locally advanced with the suspicion of lymph node metastasis underwent surgery after neoadjuvant therapy. As the surgical method, Ivor-Lewis+D2 lymph node dissection or transhiatal esophagectomy surgery was applied in lower and middle localization tumors of the esophagus, whereas McKeown surgery was preferred in middle and upper esophageal tumors. Results: Of the 103 patients included in the study, 51 (49.5%) were male and 52 (50.5%) were female. Neoadjuvant chemoradiotherapy (NCRT) was applied to 70 (67.9%) patients. While the 5-year survival rate of 70 patients who received NCRT was 69.7% (mean 56 months) of the 5-year survival rate of 33 patients who underwent direct surgery without neoadjuvant therapy was found to be 39.5 (mean 25 months), and there was a statistically significant difference observed (p<0.05). The recurrence rate in the 5-year follow-up of 70 patients who received NCRTwas 31.4% (mean 48 months). The recurrence rate in the 5-year follow-up of 33 patients who did not receive neoadjuvant treatment and underwent direct surgery was 60.6% (mean 21 months). The rate of recurrence was statistically significant between patients who received neoadjuvant therapy and those who did not receive neoadjuvant therapy (p<0.05). Conclusion: We believe that NCRT+surgery with a multidisciplinary approach in the treat-ment of patients with esophageal cancer have better survival results than those who underwent direct surgery. ABSTRACT","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135841730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Cases with Stab Wounds Presented to the Emergency Department: A 2-Year Retrospective Analysis","authors":"Adem Az","doi":"10.14744/scie.2023.58855","DOIUrl":"https://doi.org/10.14744/scie.2023.58855","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67342047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid Sequence Spinal Anesthesia for Category 1 Cesarean Section: Is it Fast, Effective, and Reliable?","authors":"K. Taşkın","doi":"10.14744/scie.2023.66674","DOIUrl":"https://doi.org/10.14744/scie.2023.66674","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67342480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Blood Groups and Mortality in Patients with Acute Pancreatitis","authors":"İzzet Ustaalioğlu","doi":"10.14744/scie.2023.02212","DOIUrl":"https://doi.org/10.14744/scie.2023.02212","url":null,"abstract":"Objective: The potential association between blood group and outcomes in acute pancreatitis has not been adequately explored. This study aimed to investigate the relationship between blood group and in-hospital mortality in patients diagnosed with acute pancreatitis. Methods: We conducted a single-center, retrospective study reviewing the medical records of patients diagnosed with acute pancreatitis between 2022 and 2023. Patient demographics, blood group type, disease severity, and in-hospital mortality were recorded. The correlation between blood group and in-hospital mortality was examined. Results: The blood group distribution among the acute pancreatitis patients was as follows: O: 31.3%, A: 49.2%, B: 16%, and AB: 3.5%. Mortality rates varied across the blood groups, with Group O having the highest mortality (8.3%), followed by Groups B (4.1%) and A (3.3%). Conclusion: Our preliminary findings suggest a potential association between blood group and mortality in acute pancreatitis, with blood group O associated with a higher mortality rate. However, due to the limitations inherent in the study’s retrospective design, these findings should be validated in future prospective studies. Understanding the role of blood group in the prognosis of acute pancreatitis could provide valuable insights into the disease’s pathophysiology and contribute to improved risk stratification and patient management. ABSTRACT","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the Adequacy of CURB-65 and qCSI Scores in Predicting the Necessity of the ICU for COVID-19 Patients","authors":"Rohat Ak","doi":"10.14744/scie.2023.76258","DOIUrl":"https://doi.org/10.14744/scie.2023.76258","url":null,"abstract":"Objective: In this study, the adequacy of the Quick COVID Severity Index (qCSI) and CURB-65 scoring systems in predicting the prognosis and need for intensive care in patients who were admitted to the emergency room and hospitalized due to Coronavirus Disease 2019 (COVID-19) were examined. Methods: The files of all adult patients over the age of 18 years who were hospitalized with the diagnosis of COVID-19 between January 1 and June 1, 2021 were reviewed retrospectively. Patients with negative reverse transcriptase-polymerase chain reaction test results, patients transferred from another hospital, and patients whose data to be used in the two risk scores could not be reached were excluded from the study. Results: A total of 325 people were included in the study, with an average age of 58.2±17.2%, 48.3% male and 51.7% female. As a result of the ROC analysis of the CURB-65 score in estimating the need for hospitalization in the intensive care unit (ICU), the area under the curve (AUC) was found to be 0.843 (95% confidence interval [CI]: 0.799–0.881), and the Youden index was 0.584, p value was 0.001. As a result of the ROC analysis of the qCSI score in estimating the need for ICU hospitalization, the AUC was found to be 0.921 (95% CI: 0.886–0.948), and the Youden’s index was 0.7520, p value was 0.001. When the value of the two scores in predicting the need for ICU admission was compared, it was found that the qCSI score was more successful than the CURB-65 score. Conclusion: In this study, the predictive powers of qCSI and CURB-65 scores in predicting the ICU requirement of COVID-19 patients admitted to the emergency department were compared. It was concluded that the qCSI score was superior to CURB-65. ABSTRACT","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracheostomy experiences in 37 children during 12 years; a retrospective study","authors":"Olga Devrim Ayvaz","doi":"10.14744/scie.2023.44452","DOIUrl":"https://doi.org/10.14744/scie.2023.44452","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67342217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Inflammatory Markers in Patients with First-episode Psychosis: A Comparative Study","authors":"Hidayet Ece Arat Çelik","doi":"10.14744/scie.2023.36036","DOIUrl":"https://doi.org/10.14744/scie.2023.36036","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Vaccination Rates for Influenza and Pneumococcal Vaccines in Patients with Chronic Obstructive Pulmonary Disease and Factors Affecting Vaccination","authors":"H. Erten","doi":"10.14744/scie.2023.67699","DOIUrl":"https://doi.org/10.14744/scie.2023.67699","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67342629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insomnia and Influencing Factors in Nonhospitalized COVID-19 Patients","authors":"İlker Yılmam","doi":"10.14744/scie.2023.34735","DOIUrl":"https://doi.org/10.14744/scie.2023.34735","url":null,"abstract":"Objective: Although there have been studies examining the frequency of insomnia in hospitalized COVID-19 patients, there have been no studies investigating insomnia in outpatients. The purpose of this study is to investigate the frequency of insomnia in non-hospitalized COVID-19 patients and the factors influencing the presence of insomnia . Methods: The study included outpatients who were diagnosed with COVID-19 by PCR, without any hospitalization indication. The Hospital Anxiety and Depression Scale (HADS) and the Insomnia Severity Index (ISI) were applied to the patients included in the study. The factors influencing the presence of insomnia were examined with a logistic regression test. Results: A total of 351 patients were included in the study. Insomnia was considered in 127 patients (36.2%) when the ISI score was ≥8 positive. When HADS scores were considered ≥8 positive, it was thought that 89 (25.4%) patients may have experienced depression and 66 (18.8%) anxiety. When the parameters influencing the presence of insomnia were evaluated by a logistic regression test, the presence of headache (p<0.0001; OR: 2.9) and fever (p=0.043; OR: 1.85) was found to be significant. It was found that the fact that anxiety (p=0.01; OR: 3.36) and depression scores were ≥8 (p=0.018; OR: 2.16) which have a significant effect on the presence of insomnia. Conclusion: Our study shows that the COVID-19 pandemic, even in mild cases, may cause sleep disorders associated with anxiety and depression triggered by both the symptoms of the infection and its negative effects on the lifestyle of society.","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperbaric Oxygen Treatment for PostCOVID-19 Sudden Sensorineural Hearing Loss Patients","authors":"Selin Gamze Sümen","doi":"10.14744/scie.2023.68542","DOIUrl":"https://doi.org/10.14744/scie.2023.68542","url":null,"abstract":"Objective: Sudden sensorineural hearing loss (SSNHL) has been reported in individuals with a previous medical history of COVID-19. This research was conducted to investigate the outcomes and characteristics of these cases following hyperbaric oxygen treatment (HBO2). Methods: This retrospective study included patients diagnosed with SSNHL, with a previous history of coronavirus disease, who underwent HBO2. Medical files from four health centers (three tertiary and one state hospital) between March 2020 and September 2021 were reviewed to evaluate the treatment outcomes. Results: The study found that 25 out of 304 patients who presented with SSNHL had a prior COVID-19 infection. The mean age of the patients was 36.2 ± 12.3 years, with 56% being male. Recovery rates were as follows: complete recovery (20%), partial improvement (20%), and minimal improvement (32%). There was a statistically significant difference between the pre-and post-treatment median values of all frequency levels (**P<0.001). Conclusion: SSNHL requires immediate management with various treatment modalities. In this study, HBO2 showed improvement in hearing loss specifically in patients with a prior history of coronavirus infection. The varied distribution of recovery rates aligns with existing literature. This is the inaugural study assessing the outcomes of HBO2 in such cases. ABSTRACT","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135838274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}