fSlnmh dnshgh `lwm pzshkhy jhrm最新文献

A case report: Improving the clinical symptoms of a pregnant woman with Covid 19 with the herbal medicine Termino One 1例报告:使用中药“Termino One”改善1例新冠肺炎孕妇临床症状

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2021-03-01 DOI: 10.52547/jmj.19.1.1

A. Hashemi, N. Kalani, Mohammad mazaher Bojani

引用次数: 0

Determination of Physicochemical Properties of Human Immunoglobulin G- Fc Fragment by Bioinformatic 生物信息学法测定人免疫球蛋白G-Fc片段的理化性质

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2021-03-01 DOI: 10.52547/JMJ.19.1.5

سهیلا روهانی, فاطمه حاجی قاسمی

{"title":"Determination of Physicochemical Properties of Human Immunoglobulin G- Fc Fragment by Bioinformatic","authors":"سهیلا روهانی, فاطمه حاجی قاسمی","doi":"10.52547/JMJ.19.1.5","DOIUrl":"https://doi.org/10.52547/JMJ.19.1.5","url":null,"abstract":"Introduction: Immunoglobulins (Igs) are defensive glycoproteins specifically recognize and destroy pathogens. Immunoglobulin G (IgG) is most abundant Ig in serum has important protective role against infections. Fragment of crystallizable (Fc) in IgG has essential role in pathogens destruction. Determination the physicochemical properties of IgG Fc is useful in well recognition of its function, diagnostic and therapeutic purposes. Bioinformatic is an efficient scientific field uses abundant biological information collected in computers for solving biologic problems. Aim of this study is recognition the physicochemical features of human IgGFc by bioinformatic. Materials and Methods: Amino acid sequence and third structure of reference human IgG were found in PDB (Protein Data Bank) database. Second IgG structure was determined by Protein Homology/analogY Recognition Engine V 2 (Phyre 2) software. Physicochemical properties (felexibility, accessibility and hydrophilicity) of IgGFc fragment were identified by IEDB (Immune Epitope Database) software. Results: According to results of this study, most accessibe, hydrophilic and felexible sites of IgGFc fragment were located to 200 – 450 amino acid sequences. Moreover most accessibe, hydrophilic and felexible positions were overlapped in 291300 and 381400 amino acid sequences and could be most probable locations of epitopes. Conclusion: Physicochemical properties of IgGFc fragment identified in present study are valuable in more exact recognition of IgG functions and its immunogenic epitopes which could be helpful in producing of specific monoclonal anti IgG antibodies for production IgG diagnostic tools, optimizing existing kits, development of similar proteins for diagnostic and therapeutic purposes and phylogenic studies.","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44809818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trend of animal bites and related ecological factors in Jahrom county during 2014-2018 2014-2018年嘉伦县动物咬伤趋势及相关生态因子分析

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2020-12-01 DOI: 10.52547/jmj.18.4.5

Davood Alian, Mahdieh Namayande, M. Ghaneian, M. Ehrampoosh, F. Madadizadeh

引用次数: 1

Effect of citric acid on p53 and p21 genes expression of the human gastric Adenocarcinoma cell line(AGS) 柠檬酸对人胃癌细胞系p53和p21基因表达的影响

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2020-12-01 DOI: 10.52547/jmj.18.4.3

Hamed Nasr Isfahani, L. Rouhi, Noosha Ziya Jahromi, Khalil Khashei

引用次数: 0

Case Report: A case study of abdominal aortic aneurysm in a bladder cancer patient 病例报告：一例癌症患者腹主动脉瘤的病例研究

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2020-12-01 DOI: 10.52547/JMJ.18.4.6

مرضیه حق بین, نوید کلانی, الهام رفیعی, نرگس رحمانیان

引用次数: 0

The effect of fentanyl addition to bupivacaine on shivering and vomiting nausea in patients undergoing femoral fracture surgery by spinal anesthesia: A double-blind randomized clinical trial 芬太尼与布比卡因联合应用对腰麻股骨骨折手术患者寒战和呕吐恶心的影响：一项双盲随机临床试验

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2020-12-01 DOI: 10.52547/JMJ.18.4.2

javad vagharfard, A. Rastgarian, M. Rahmanian, M. pourmokhtari, Mohammad Hasan Damshenas, S. Taban, Hasan Zabetian, N. Kalani, N. Hatami

引用次数: 1

A case report of scrotal mass the first clinical manifestation of multiple myeloma 多发性骨髓瘤第一临床表现阴囊肿块1例报告

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2020-12-01 DOI: 10.52547/jmj.18.4.7

A. Yousefi, R. Inaloo, Hossein Hakimellahi

引用次数: 0

Effect of Crocin on miRNA-15a expression in EBV infected transformed B cell Crocin对EBV感染转化B细胞miRNA-15a表达的影响

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2020-10-01 DOI: 10.52547/jmj.18.3.21

Abdolreza Sotoodeh Jahromi, M. Moradzadeh, M. Kargar, F. Kafilzadeh, M. Jamalidoust

引用次数: 1

Prevalence of Dyslipidemia and its Determinants in Jahrom: a Population-based Cross-sectional Study 血脂异常的患病率及其决定因素:一项基于人群的横断面研究

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2020-10-01 DOI: 10.52547/jmj.18.3.49

F. Hooshmand, M. Shojaei, K. Rahmanian

引用次数: 0

Determining the relationship between adverse events and their associated risk factors in the transfer of patients from intensive care units 确定重症监护病房患者转移过程中不良事件及其相关危险因素之间的关系

fSlnmh dnshgh `lwm pzshkhy jhrm Pub Date : 2020-10-01 DOI: 10.52547/jmj.18.3.1

Mahdi Asadiyan, M. Heidari, Hamid Reza Dolatkhah

{"title":"Determining the relationship between adverse events and their associated risk factors in the transfer of patients from intensive care units","authors":"Mahdi Asadiyan, M. Heidari, Hamid Reza Dolatkhah","doi":"10.52547/jmj.18.3.1","DOIUrl":"https://doi.org/10.52547/jmj.18.3.1","url":null,"abstract":"Introduction: Transfer of critically ill patients admitted to intensive care units mainly for the purpose of performing diagnostic and therapeutic procedures can be associated with adverse events. The purpose of this study was to determine the relationship between the incidence of adverse events and its associated risk factors during the transfer of ICU Patients. Material & Methods: In this descriptive cross-sectional study, patient data were collected through a checklist of adverse events over a 6-month period. The data were analyzed by descriptive and analytical statistics using SPSS software (version 22). Results: 536 patients (91.2%) had adverse events. The incidence of patient-related, staff-related, and equipmentrelated adverse events was 65.5%, 73.3%, and 7.8%, respectively. The incidence of adverse events was higher in men than women (P= 0.035). The incidence of adverse events in stroke transfer (51.9%) was significantly higher than other methods (P<0.001). Incidence of adverse events in ICU was significantly higher than CCU (P= 0.001). There was a statistically significant correlation between the occurrence of adverse events and the presence of equipment such as oxygen cylinder (P<0.001), cardiac monitor (P=0.047), portable ventilator (P=0.004), pulse oximeter (P<0.001) and bedside railing (P<0.001). Conclusion: The results showed that the incidence of adverse events was high. Organizations must identify and actively address risks during the transition. The use of checklists and communication tools related to data transfer can improve the quality and safety of transfer.","PeriodicalId":33852,"journal":{"name":"fSlnmh dnshgh `lwm pzshkhy jhrm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42580633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0