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Effects of Mammary Surgery on Prolactin Secretion in Common and in Triple Negative Breast Cancer Patients 乳腺手术对普通及三阴性乳腺癌患者泌乳素分泌的影响
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0403002
P. Lissoni, F. Brivio, Arianna Dissoni, G. Messina, Vezika Cenaj, E. Porta, R. Trampetti, G. Fede
{"title":"Effects of Mammary Surgery on Prolactin Secretion in Common and in Triple Negative Breast Cancer Patients","authors":"P. Lissoni, F. Brivio, Arianna Dissoni, G. Messina, Vezika Cenaj, E. Porta, R. Trampetti, G. Fede","doi":"10.20431/2456-0561.0403002","DOIUrl":"https://doi.org/10.20431/2456-0561.0403002","url":null,"abstract":"Despite the well documented potential stimulatory activity of prolactin (PRL) on mammary tumors, hyperprolactinemia following breast surgery has proven to be able to predict a more favourable prognosis in breast cancer. This apparent controversial result is probably due to mammary stimulation that induces PRL secretion in normal conditions, therefore the failure of PRL increase after breast surgery could reflect an alteration in the neuroendocrine control of mammary tissue growth and differentiation. On this basis, a study was planned in order to investigate the effects of breast surgery on PRL secretion in Triple Negative Breast Cancer (TNBC), which represents the most malignant subtype of mammary tumors. The study included 100 breast cancer patients treated by quadrantectomy, evaluating PRL serum levels before and 7 days after surgery. The diagnosis of TNBC occurred in 16/100 investigated patients. Postsurgical hyperprolactinemia was observed in 53/84 (63%) patients with common breast cancer and in only 2/16 (13%) TNBC patients. This difference was statistically significant. The present preliminary study, demonstrates a lower frequency of surgery-induced hyperprolactinemia in TNBC compared to the other mammary tumorhistotypes and furthermore it suggests that the more aggressive behavior of TNBC could depend to some extent on a more pronounced alteration in the neuroendocrine control of mammary tissue.","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115396390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Significance of C-reactive protein in Pregnancy Induced Hypertension c反应蛋白在妊高征中的临床意义
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0402002
A. Olumodeji, O. Adewara, Olabisi Timothy, Adeyemo, S. M. Ghazali, P. Olowoyo
{"title":"Clinical Significance of C-reactive protein in Pregnancy Induced Hypertension","authors":"A. Olumodeji, O. Adewara, Olabisi Timothy, Adeyemo, S. M. Ghazali, P. Olowoyo","doi":"10.20431/2456-0561.0402002","DOIUrl":"https://doi.org/10.20431/2456-0561.0402002","url":null,"abstract":"Pregnancy Induced Hypertension is hypertension with or without proteinuria emerging after 20 weeks gestation, but resolving not later than 12 weeks postpartum.[1] Hypertensive disorders of pregnancy contributes significantly to morbidity and mortality in the fetus and mother both in the developed and developing countries with PIH listed as one of the top three causes of maternal mortality.[2] Abstract","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121447495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rates and Determinants of Successful Vaginal Birth after a Previous Caesarean Section: A Prospective Cohort Study 既往剖宫产后阴道分娩成功率和决定因素:一项前瞻性队列研究
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0402001
G. Eleje, P. C. Okam, E. I. Okaforcha, Chinekwu, Sochukwu Anyaoku
{"title":"Rates and Determinants of Successful Vaginal Birth after a Previous Caesarean Section: A Prospective Cohort Study","authors":"G. Eleje, P. C. Okam, E. I. Okaforcha, Chinekwu, Sochukwu Anyaoku","doi":"10.20431/2456-0561.0402001","DOIUrl":"https://doi.org/10.20431/2456-0561.0402001","url":null,"abstract":"Caesarean delivery has remained an important surgical intervention in contemporary obstetric practice [1-3]. Worldwide, primary and repeat caesarean delivery rates have reached their highest levels [4-6]. Even though, variation exists in the rates across countries; currently the rate ranges from 10% to 40% [6-8]. Due to increased risk of maternal complications on repeat caesarean section (CS) and safety of vaginal birth after caesarean section (VBAC), trial of labour for selected group of patients with a previous lower segment transverse scar has become a favorite strategy [7]. Abstract","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128237844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Fatty Liver Index and Serum Copeptin as Early Predictors of Gestational Diabetes Mellitus in Non-diabetic Pregnant Women 脂肪肝指数和血清Copeptin作为非糖尿病孕妇妊娠期糖尿病的早期预测指标
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0401003
H. Hamza
{"title":"Fatty Liver Index and Serum Copeptin as Early Predictors of Gestational Diabetes Mellitus in Non-diabetic Pregnant Women","authors":"H. Hamza","doi":"10.20431/2456-0561.0401003","DOIUrl":"https://doi.org/10.20431/2456-0561.0401003","url":null,"abstract":"Methods: The study included 385 pregnant women at the 6 GW for clinical evaluation, determination of body mass index (BMI) and waist circumference and gave blood samples for estimation of serum triglyceride (TG), γ-glutamyl transferase (GGT) insulin and CP and underwent the 75-oral glucose tolerance test (75OGTT). Fatty liver index and homeostasis model assessment of IR (HOMA-IR) were calculated. At the 24 GW, 75-OGTT and serum insulin were re-evaluated and women developed GDM were collected as GDM group and women who were free of GDM till the 24 GW as control group. Results: At 24 GW, all studied women had higher blood glucose, serum insulin, TG and GGT with increased HOMA-IR and FLI scores in comparison to 6 GW measures. The increase was non-significant in 338 women (controls) and was significant in 47 women (GDM group) who showed significantly higher measures compared to controls for a frequency of GDM of 12.2%. At 6 GW serum CP levels were significantly higher in GDM than in control women. Statistical analyses defined high FLI and serum CP at the 6 GW as significant predictors for subsequent development of GDM.","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123979792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of 17-Alpha-Hydroxyprogesterone Caproate on Reducing the Rate of Emergent Cesarean Delivery in Women with Placenta Accrete Spectrum: A Randomized Controlled Study 17- α -羟孕酮己酸对降低胎盘增生谱妇女紧急剖宫产率的影响:一项随机对照研究
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0401001
H. Sallam, N. Shady, H. M. Ahmed
{"title":"The Effect of 17-Alpha-Hydroxyprogesterone Caproate on Reducing the Rate of Emergent Cesarean Delivery in Women with Placenta Accrete Spectrum: A Randomized Controlled Study","authors":"H. Sallam, N. Shady, H. M. Ahmed","doi":"10.20431/2456-0561.0401001","DOIUrl":"https://doi.org/10.20431/2456-0561.0401001","url":null,"abstract":"Methods: The study was a randomized open-label clinical trial conducted at a tertiary university hospital outpatient clinic and some private settings at Aswan governorate, Egypt, between January 2015 and October 2018. We included women who asymptomatic pregnant women with a diagnosed placenta PAS at 28-30 weeks gestation. They were randomized into two groups: group I (received no treatment), group II (received an IM. dose of 250 mg 17-alpha-Hydroxyprogesterone caproate once a week). In each group, Follow-up visits were performed every week then admission was done at 36 weeks at our university hospital. Scheduled caesarian section was done at completed 37 weeks unless otherwise required.","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130176358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How Women in Search of Suitable Contraceptive Methods can Remedy the Lack of Counseling and Circumvent Untrustworthy Information Disseminated by Various Media 寻找合适避孕方法的女性如何弥补咨询不足，规避各种媒体传播的不可信信息
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0403001
K. Kraetschmer
{"title":"How Women in Search of Suitable Contraceptive Methods can Remedy the Lack of Counseling and Circumvent Untrustworthy Information Disseminated by Various Media","authors":"K. Kraetschmer","doi":"10.20431/2456-0561.0403001","DOIUrl":"https://doi.org/10.20431/2456-0561.0403001","url":null,"abstract":"Results: The result of the analysis performed is a synoptically structured overview of the currently available methods which are ranked primarily according to the parameter safety, but also according to efficacy, continuation of use, i.e., satisfaction, convenience, and cost. Safety (no harm in the sense of “nil nocere“) Efficacy PerfectTypical use Satisfaction [% women continuing after one year] Convenience Cost & Specifications","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"182 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123555246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Effects of Single Agent Rectal Diclofenac versus its Combination with Intramuscular Pentazocine on Post Caesarean Section Pain Relief in a Tertiary Institution in Southern Nigeria 在尼日利亚南部的一所高等教育机构中，直肠单药双氯芬酸与肌注戊唑嗪联合使用对剖宫产后疼痛缓解的比较效果
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0402003
N. J. Kwosah, D. A. Macpepple
{"title":"Comparative Effects of Single Agent Rectal Diclofenac versus its Combination with Intramuscular Pentazocine on Post Caesarean Section Pain Relief in a Tertiary Institution in Southern Nigeria","authors":"N. J. Kwosah, D. A. Macpepple","doi":"10.20431/2456-0561.0402003","DOIUrl":"https://doi.org/10.20431/2456-0561.0402003","url":null,"abstract":"Caesarean section (C/S) is one of the most common surgeries done globally in obstetrics. This operation commonly induces severe pain, hence reducing the pain after C/S is very important. The International Association for the Study of Pain (IASP) has noted that uncontrolled acute pain not only leads to discomfort and suffering, but can also have unwanted consequences, such as delayed wound healing, increased risk of morbidity, prolonged hospital stay, and the risk of developing chronic persistent pain [1]. In fact, in any post-caesarean section patient, early ambulation, breastfeeding and maternal bonding with the infant may be interfered by poor pain management [2].","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117033763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Temporary Balloon Occlusion of the Internal Iliac Arteries to Prevent Massive Hemorrhage during Cesarean Delivery in a Patient with Placenta Previa Increta - Case Report 临时球囊封堵髂内动脉预防1例前置胎盘前置型剖宫产术中大出血
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0401002
K. Pyra, L. Swiatlowski, M. Grzechnik, P. Dziduch, M. Kuczyńska
{"title":"Temporary Balloon Occlusion of the Internal Iliac Arteries to Prevent Massive Hemorrhage during Cesarean Delivery in a Patient with Placenta Previa Increta - Case Report","authors":"K. Pyra, L. Swiatlowski, M. Grzechnik, P. Dziduch, M. Kuczyńska","doi":"10.20431/2456-0561.0401002","DOIUrl":"https://doi.org/10.20431/2456-0561.0401002","url":null,"abstract":"In recent years, the number of cesarean deliveries has been constantly increasing, leading to higher incidence of complications due to abnormal placental location or attachment in the following pregnancies (1), with an obstetric hemorrhage in the postpartum period being the most severe of them. Placenta increta is a serious obstetrical complication caused by a defect in the decidua basalis resulting in an abnormally invasive placental implantation. Several studies have shown that conservative management by leaving placenta in situ was successful in many cases with invasive placental implantation (2). But there were still a number of failed cases with delayed hysterectomy and severe maternal morbidity. Placenta accreta and previa are the two forms of placental maldevelopment, which constitute the major cause of severe peripartum bleeding the most frequent cause of maternal mortality with an incidence rate reported as high as 30% (3-5). These two conditions still pose a challange in the obstetric practice (6). Case below is an interesting and informative on the basis of which we present diagnostic methods and a safe, minimally invasive way of delivery which is at risk of massive hemorrhage.","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123111659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrosalpinx and IVF: Effect and Management 输卵管积水和体外受精:效果和处理
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0401004
A. El-Mazny
{"title":"Hydrosalpinx and IVF: Effect and Management","authors":"A. El-Mazny","doi":"10.20431/2456-0561.0401004","DOIUrl":"https://doi.org/10.20431/2456-0561.0401004","url":null,"abstract":"Laparoscopic surgery, including salpingectomy or tubal occlusion, has been shown to improve IVF outcome for patients with a hydrosalpinx [10]. However, this procedure has many drawbacks, including its invasiveness, technical difficulty if there are pelvic adhesions, the possibility of surgical injury (e.g. visceral injury, vascular damage, or unintended Abstract: Patients with a hydrosalpinx have been found to have significantly poorer IVF outcome than do patients with tubal factor infertility but no hydrosalpinx. The exact mechanism by which hydrosalpingial fluid impacts implantation and pregnancy is not clear; however, many theories exist. The rationale behind treatment of hydrosalpinx prior to IVF is to eliminate the detrimental effect of hydrosalpingel fluid either by removing the fallopian tube (salpingectomy) or by isolating it from the uterine cavity (laparoscopic or hysteroscopic occlusion, or Essure insert), or by aspirating the hydrosalpingel fluid (ultrasound-guided).","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114713874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Prospective Follow up of Metabolic Changes among Obese Women using two Different Regimens of Ethinylestradiol/ Drospirenone Containing Contraceptive Pills 两种含炔雌醇/屈螺酮避孕药方案对肥胖妇女代谢变化的前瞻性随访
ARC Journal of Gynecology and Obstetrics Pub Date : 1900-01-01 DOI: 10.20431/2456-0561.0402004
Mohamed Emarh, R. Dawood
{"title":"A Prospective Follow up of Metabolic Changes among Obese Women using two Different Regimens of Ethinylestradiol/ Drospirenone Containing Contraceptive Pills","authors":"Mohamed Emarh, R. Dawood","doi":"10.20431/2456-0561.0402004","DOIUrl":"https://doi.org/10.20431/2456-0561.0402004","url":null,"abstract":"This prospective comparative study was conducted at departments of Obstetrics & Gynecology, in Menoufia University hospital, Menoufia governorate, Egypt; between the beginnings of August 2017 and September 2019. Before initiating the study, the local ethical review board approved the study protocol with all included participants signed the informed consent form, after thorough explanation of the study objectives.","PeriodicalId":337677,"journal":{"name":"ARC Journal of Gynecology and Obstetrics","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116336162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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