Clinical Parkinsonism Related Disorders最新文献

{"title":"The impact of an active lifestyle on markers of intestinal inflammation in Parkinson’s disease: Preliminary findings","authors":"Nesrine Chtioui ,&nbsp;Christian Duval ,&nbsp;David H. St-Pierre","doi":"10.1016/j.prdoa.2025.100301","DOIUrl":"10.1016/j.prdoa.2025.100301","url":null,"abstract":"<div><div>Alterations in the gut microbiota leading to intestinal inflammation and decreased levels of Short Chain Fatty Acids (SCFA) has been observed in Parkinson’s disease (PD).</div></div><div><h3>Objective</h3><div>The aim of this study was to compare these factors between physically active and less active people with PD.</div></div><div><h3>Methods</h3><div>Stool, plasma samples and clinical data were collected from 35 people with PD (20 men and 15 women, mean age 66 years). Their level of physical activity was retrospectively assessed using the International Physical Activity Questionnaire (IPAQ). Participants were divided into two groups based on their physical activity level: Active and Inactive. Both SCFA and calprotectin, a marker of intestinal inflammation, were respectively measured by GC–MS and ELISA, according to standardized, validated protocols.</div></div><div><h3>Results</h3><div>Age, disease stage (Hoen &amp; Yahr) and Montreal Cognitive Assessments (MoCA) were similar between groups. Acetate, propionate, and butyrate levels were significantly higher in the Active group than in the Inactive group. In addition, fecal calprotectin was significantly lower in the Active group than in the Inactive group. The constipation values were significantly lower in the Active group.</div></div><div><h3>Conclusion</h3><div>Our results suggest that an active lifestyle with regular physical activity is beneficial in patients with PD, through increased production of SCFA by the gut microbiome, and reduced intestinal inflammation and constipation.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100301"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating YouTube as a source of information on hemifacial spasm","authors":"Kimberly L. Po ,&nbsp;Alfeo Julius R. Sy ,&nbsp;Roland Dominic G. Jamora","doi":"10.1016/j.prdoa.2025.100311","DOIUrl":"10.1016/j.prdoa.2025.100311","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>Patients increasingly turn to YouTube for trustworthy health-related information, prompting a study to evaluate the quality and reliability of videos about hemifacial spasms (HFS) available on the platform.</div></div><div><h3>Materials and Methods</h3><div>In August 2024, a systematic search was conducted using a formal strategy to identify relevant videos. Two independent neurology resident physicians reviewed each video, scoring it with the validated modified DISCERN (mDISCERN) tool for reliability and the Global Quality Scale (GQS) for content quality. Videos were categorized based on their purpose and assessed for video/audio quality, accuracy, comprehensiveness, and procedure-specific content.</div></div><div><h3>Results</h3><div>The study included 44 videos. According to GQS, 17 (38.6 %) were rated as high quality, 14 (31.8 %) as good, 5 (17 %) as medium, and 8 (18.2 %) as poor quality. On the mDISCERN scale, 24 (54.5 %) were deemed reliable, while 9 (20.5 %) were unreliable. Videos created by physicians, academic institutions, and reputable health information websites scored higher on both mDISCERN and GQS compared to other sources. A strong positive correlation was found between mDISCERN and GQS scores (r = 0.925, p &lt; 0.001), indicating that higher reliability was linked to better content quality.</div></div><div><h3>Conclusion</h3><div>YouTube offers valuable resources for HFS patients and caregivers. Videos produced by healthcare professionals and academic institutions offered particularly accurate insights, enhancing patients’ understanding of the condition’s pathophysiology and treatment options, and serving as a useful complement to healthcare professionals’ knowledge. Healthcare professionals and academic institutions have a pivotal role in creating and promoting high-quality educational content. Future efforts should focus on increasing the availability of reliable, expert-verified videos to improve overall quality of information accessible to patients.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100311"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The vestibulo-ocular and vestibulospinal reflexes minimally impact the freezing of gait in patients with early-to-moderate Parkinson’s disease","authors":"Yukang Kim ,&nbsp;Donghoon Woo ,&nbsp;Hanseob Kim ,&nbsp;Kyoungwon Baik ,&nbsp;Sun-Uk Lee ,&nbsp;Chan-Nyoung Lee ,&nbsp;Gerard J. Kim ,&nbsp;Seoui Kwag ,&nbsp;Hyunsoh Park ,&nbsp;Ji-Soo Kim ,&nbsp;Kun-Woo Park","doi":"10.1016/j.prdoa.2025.100319","DOIUrl":"10.1016/j.prdoa.2025.100319","url":null,"abstract":"<div><h3>Introduction</h3><div>Freezing of gait (FOG) is a disabling condition that often leads to falls and severe postural instability in patients with Parkinson’s disease (PD). This study aimed to determine whether FOG is associated with the integrity of the vestibulo-ocular (VOR) and vestibulospinal reflexes (VSR).</div></div><div><h3>Methods</h3><div>We retrospectively collected 138 patients with de novo PD at a tertiary medical center between February 2022 and February 2025. Each patient was queried and assessed for FOG status during the initial assessment. All patients underwent video head-impulse tests (video-HIT), cervical vestibular-evoked myogenic potential (cVEMP), ocular vestibular-evoked myogenic potential (oVEMP), and motion analysis.</div></div><div><h3>Results</h3><div>FOG was observed in 23 patients (23/138, 17 %). The head impulse gain of the VOR did not differ between freezers and non-freezers in any semicircular canal. The new FOG questionnaire score showed no correlation with the VOR gain for any canal. The oVEMP and cVEMP parameters did not differ between freezers and non-freezers either. Multivariable logistic regression analysis revealed a positive association between FOG and MDS-UPDRS-III (<em>p =</em> 0.016). However, FOG was not associated with the VOR gain in any canal or abnormalities on oVEMP or cVEMP.</div></div><div><h3>Conclusions</h3><div>Our preliminary data suggest that FOG is associated with the severity of motor symptoms in patients with early-to-moderate PD. While the integrity of the VOR or VSR is not currently associated with FOG, a well-designed future study could provide more nuanced insights into the relationship with these factors.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100319"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal microvascular and microcirculatory responses related to cognition improvement following yoga training in patients with Parkinson’s disease","authors":"Hong Jiang ,&nbsp;Kirill Stremousov ,&nbsp;Yunhai Dai ,&nbsp;Bonnie Levin ,&nbsp;Amanda Virgets ,&nbsp;Andrew Hoover ,&nbsp;Kylie J. Martinez ,&nbsp;Joseph Signorile ,&nbsp;Jianhua Wang","doi":"10.1016/j.prdoa.2025.100329","DOIUrl":"10.1016/j.prdoa.2025.100329","url":null,"abstract":"<div><h3>Purpose</h3><div>To determine the relationship of retinal microcirculatory responses to cognitive function following yoga training in patients with Parkinson’s disease (PD).</div></div><div><h3>Methods</h3><div>Twenty patients with diagnosed PD were recruited, and retinal imaging was successful on 17 patients (age 71.8 ± 7.2 years old, nine females). Retinal capillary perfusion density (CPD) was imaged using optical coherence tomography angiography (OCTA), and retinal blood flow (RBF) was imaged using a retinal function imager (RFI). All patients participated in three 1-hour YogaCue or Hatha yoga classes per week for 24 consecutive weeks. Pearson correlation analyses determined the relationship between the changes in retinal microcirculatory responses and cognitive function.</div></div><div><h3>Results</h3><div>Increased RBF was significantly related to the changes of CPD in all retinal slabs, including superficial and deeper vascular plexuses and retinal vascular network (6 mm scan, r ranged 0.58–0.83, P &lt; 0.05). The increased RBF and CPD of superficial vascular plexus (6 mm scan) were related to the improvements (i.e., shorter time) in trail-making A performance (r = −0.66, P &lt; 0.01 and r = −0.58, P &lt; 0.05, respectively). In addition, the change of CPD in the retinal vascular network was related to improvement in Hopkins verbal delayed recall (r = 0.50, P &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>This is the first study exploring the relationship between retinal microcirculatory responses to yoga exercise and cognitive function in PD patients. The synergistic effect of CPD and RBF may be developed into ocular indicators for monitoring the effect of cognitive improvement from yoga exercise in patients with PD.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100329"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term infective complications of deep brain stimulation in Parkinson’s disease: A 22-year follow-up","authors":"Riccardo Antonio Ricciuti ,&nbsp;Matteo Maria Ottaviani ,&nbsp;Fabrizio Mancini ,&nbsp;Valentina Liverotti ,&nbsp;Daniele Marruzzo ,&nbsp;Massimo Marano ,&nbsp;Francesca Barbieri ,&nbsp;Riccardo Paracino ,&nbsp;Serena Pagano ,&nbsp;Vincenzo Di Lazzaro ,&nbsp;Mauro Dobran","doi":"10.1016/j.prdoa.2025.100335","DOIUrl":"10.1016/j.prdoa.2025.100335","url":null,"abstract":"<div><h3>Introduction</h3><div>Deep brain stimulation (DBS) is an established treatment for Parkinson’s disease (PD), but infections remain a significant concern. This study evaluated infection rates and their impact in PD patients who underwent subthalamic nucleus (STN)-DBS over a 23-year period.</div></div><div><h3>Methods</h3><div>A total of 172 PD patients who underwent bilateral STN-DBS between 2000 and 2023 were included in this retrospective study. Patients were followed up for periods ranging from 5 to 22 years, with regular assessments conducted to monitor both clinical outcomes and the occurrence of infections. The study analyzed the timing of infections onset, clinical features, microbiological data, management and outcomes.</div></div><div><h3>Results</h3><div>The overall infection rate was 8.7 % over the follow-up period (15/172). Most of the infections (63.6 %) involved the implantable pulse generator (IPG) subcutaneous pocket, developed after a median of 22 months and were related to the number of substitutions with a notable peak in incidence after the third replacement (3.3 ± 1.5). All the infected devices were non-rechargeable and Staphylococcus epidermidis was the isolated pathogen in all cases except by one. Surgical revision of the IPG pocket was necessary in 46.2 % of cases while all the others were treated by antibiotics. Factors that significantly correlated with infections were the years elapsed since DBS implantation, BMI decrease, and the number of IPG replacements.</div></div><div><h3>Conclusions</h3><div>While STN-DBS remains effective for PD, infection risk rises with time, particularly during IPG replacements. Long-term follow-up and timely management are vital for sustaining therapeutic benefits.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100335"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the enigmatic: Primary progressive apraxia of speech – A case report","authors":"Mateusz Bernad ,&nbsp;Renata Kowalska-Taczanowska ,&nbsp;Karolina Duszyńska- Wąs ,&nbsp;Joanna Mączewska ,&nbsp;Piotr Alster ,&nbsp;Dariusz Koziorowski ,&nbsp;Monika Figura","doi":"10.1016/j.prdoa.2025.100304","DOIUrl":"10.1016/j.prdoa.2025.100304","url":null,"abstract":"<div><div>Primary progressive apraxia of speech (PPAOS) is a rare neurodegenerative disorder that saliently affects motor speech programming and planning. Linguistic function remains intact in the early stages of PPAOS.</div><div>Although PPAOS shares a similar symptomatology to conditions such as primary progressive aphasia (PPA) and dysarthria, it is important to remember that this disorder constitutes its own distinct clinical syndrome. PPAOS is characterized by an individually variable disease course, with a steady progression in speech deterioration. In later stages, this disorder may additionally present with symptoms such as oral apraxia, dysarthria, dysphagia, aphasia, and parkinsonian syndromes similar to either progressive supranuclear palsy (PSP) or corticobasal syndrome (CBS). 4-repeat tauopathy is the most common pathology associated with PPAOS. In this study, we present a case of a female patient suffering from PPAOS, detailing her clinical course during a 44-year long follow-up. As PPAOS is a disorder with a worldwide poorly-documented prevalence, there is limited data in literature on the subject. We thus bring this case to public discussion. We also recommend further investigating this disorder, as we would then be able to unify diagnostic and therapeutic approaches for PPAOS.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100304"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-dipeptidyl-peptidase-like protein-6 (DPPX) autoimmune encephalitis associated with severe multifocal dystonia","authors":"Eric Roddy ,&nbsp;Erik Gentry ,&nbsp;Victoria Holiday ,&nbsp;David Robertson ,&nbsp;Peter Hedera","doi":"10.1016/j.prdoa.2025.100320","DOIUrl":"10.1016/j.prdoa.2025.100320","url":null,"abstract":"<div><div>Anti-DPPX encephalitis is a rare form of autoimmune encephalitis characterized antibodies against a subunit of Kv4.2 potassium channels. Characteristic clinical features include cognitive dysfunction, parasomnias, psychosis, and seizures. Motor symptoms typically include myoclonus, tremor, and midline ataxia. DPPX encephalitis presenting as new-onset focal dystonia has not been previously described.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100320"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expectations regarding regenerative medicine and attitudes toward invasive surgical therapies in patients with Parkinson’s disease: A cross-sectional survey","authors":"Mika Watabe ,&nbsp;Atsushi Shima ,&nbsp;Kiyoaki Takeda ,&nbsp;Yuta Terada ,&nbsp;Yusuke Sakato ,&nbsp;Akira Nishida ,&nbsp;Ikko Wada ,&nbsp;Haruhi Sakamaki-Tsukita ,&nbsp;Kenji Yoshimura ,&nbsp;Daisuke Kambe ,&nbsp;Koji Furukawa ,&nbsp;Masanori Sawamura ,&nbsp;Etsuro Nakanishi ,&nbsp;Yosuke Taruno ,&nbsp;Hodaka Yamakado ,&nbsp;Ryosuke Takahashi ,&nbsp;Nobukatsu Sawamoto","doi":"10.1016/j.prdoa.2025.100341","DOIUrl":"10.1016/j.prdoa.2025.100341","url":null,"abstract":"<div><h3>Introduction</h3><div>Pharmacological control of the motor symptoms of Parkinson’s disease (PD) is challenging with disease progression. Device-aided therapies help relieve these symptoms but are invasive and require specific management. Induced pluripotent stem (iPS) cells avoid ethical concerns and may prevent immune rejection in autologous transplants. Allogeneic iPS cells are considerably more practical, despite potential concerns regarding tumor formation post-transplantation. The present study aimed to clarify the perceptions and acceptance of patients with PD regarding regenerative medicine, invasive surgical treatments (deep brain stimulation, levodopa-carbidopa intestinal gel), and cell transplantation (iPS cells, embryonic stem cells, fetal-derived cells).</div></div><div><h3>Methods</h3><div>This prospective cross-sectional survey of 102 patients with PD applied a new questionnaire based on a previous survey of the general public’s perception of regenerative medicine.</div></div><div><h3>Results</h3><div>Cell-based therapies were the most popular choice, with 86.1 % of responders choosing it, mainly due to “improvement in quality of life” (69.1 %), “the possibility of slowing the disease progression” (66.2 %), and “treatment effectiveness” (51.5 %). Among these patients, 47.1 % expected regenerative medicine to become the standard therapy within several years and 82.4 % believed that regenerative medicine was safe. Autologous iPS cells were accepted by 83.8 % of the patients, while 52.5 % accepted allogeneic iPS cells.</div></div><div><h3>Conclusions</h3><div>Patients had high expectations for the therapeutic effects of cell-based therapies and were optimistic about its early implementation and safety in regenerative medicine, with iPS cells being the most accepted for transplantation. The present findings should be confirmed in a larger cohort, as these findings are based on a limited sample.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100341"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality Measure Adherence in Parkinson’s Disease: A Single Center Experience***Parkinson’s Disease Quality Measures","authors":"Tanner Bradford ,&nbsp;Bryanna De Lima ,&nbsp;Kahley Milauskas ,&nbsp;Mary Brooks ,&nbsp;Suvi Neukam ,&nbsp;Lee E. Neilson","doi":"10.1016/j.prdoa.2025.100337","DOIUrl":"10.1016/j.prdoa.2025.100337","url":null,"abstract":"<div><h3>Background</h3><div>Patients with Parkinson’s Disease (PWPs) often have both motor and non-motor manifestations requiring specialized care. Neurologists typically lead their care; however, the population of PWPs is exceeding the supply of neurologists. Primary care providers (PCPs) may need to contribute to improve care.</div></div><div><h3>Objective</h3><div>To measure American Academy of Neurology quality metric (QM) adherence between neurologists and PCPs for PWPs.</div></div><div><h3>Methods</h3><div>We conducted a single-center retrospective, descriptive analysis assessing 14 QMs in the past year for PWPs established with a neurologist and PCP. McNemar’s test assessed statistical differences between groups. Logistic regression models explored the impact of age, sex, and visit frequency on QM adherence</div></div><div><h3>Results</h3><div>On average, 8.9 QMs were addressed among 89 PWPs. Motor complications, rehabilitation referrals, falls, and autonomic dysfunction were the most often addressed while apathy and impulse control disorder were the least. Neurologists alone met motor complications, psychosis, impulse control disorder, and sleep disturbance significantly more than PCPs alone while PCPs assessed depression and advance care planning more often. PCP involvement improved adherence throughout. Depression, apathy, and advance care planning metric adherence were significantly impacted by age and/or visit frequency.</div></div><div><h3>Conclusions</h3><div>A team-based approach to quality metric adherence may reduce the burden on providers and improve care for PWPs.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100337"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143931435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding personal preferences to promote exercise adherence in Parkinson’s disease","authors":"Caro I. Cools ,&nbsp;Sonja A. Kotz ,&nbsp;Bastiaan R. Bloem ,&nbsp;Nienke M. de Vries ,&nbsp;Annelien A. Duits","doi":"10.1016/j.prdoa.2025.100336","DOIUrl":"10.1016/j.prdoa.2025.100336","url":null,"abstract":"<div><h3>Introduction</h3><div>Exercise is a recognized treatment for people with Parkinson’s Disease (PwP), but personal exercise preferences are rarely considered in exercise intervention studies. Yet these are critical for understanding motivation and to ascertain long-term exercise adherence in PwP. This study compared preferred exercise types among PwP with exercise types investigated in prior research.</div></div><div><h3>Method</h3><div>672 PwP participated in an online survey, answering questions about currently practiced and preferred exercise types. Besides, a brief review was performed, evaluating exercise types deployed in prior studies. The preferred exercise types of PwP were subsequently compared to exercise types used in prior research.</div></div><div><h3>Results</h3><div>PwP mainly preferred the same exercises that they were currently practicing. These preferences did not necessarily align with exercise types reported in prior studies. The top 5 highly preferred sport categories but relatively little studied were walking, biking, swimming, boxing, and tennis.</div></div><div><h3>Conclusion</h3><div>Future intervention studies may benefit from considering personal preferences to both strengthen and understand exercise adherence.</div></div>","PeriodicalId":33691,"journal":{"name":"Clinical Parkinsonism Related Disorders","volume":"12 ","pages":"Article 100336"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143918422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}