Antidiabetic drugs in Parkinson’s disease

IF 1.9 Q3 CLINICAL NEUROLOGY
Yoshajandith Aguirre-Vidal , Sergio Montes , Ana Carolina Mota-López , Gabriel Navarrete-Vázquez
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引用次数: 0

Abstract

This review explores the intricate connections between type 2 diabetes (T2D) and Parkinson’s disease (PD), both prevalent chronic conditions that primarily affect the aging population. These diseases share common early biochemical pathways that contribute to tissue damage. This manuscript also systematically compiles potential shared cellular mechanisms between T2D and PD and discusses the literature on the utilization of antidiabetic drugs as potential therapeutic options for PD. This review encompasses studies investigating the experimental and clinical efficacy of antidiabetic drugs in the treatment of Parkinson’s disease, along with the proposed mechanisms of action. The exploration of the benefits of antidiabetic drugs in PD presents a promising avenue for the treatment of this neurodegenerative disorder.

帕金森病中的抗糖尿病药物
这篇综述探讨了 2 型糖尿病(T2D)和帕金森病(PD)之间错综复杂的联系。这两种疾病有共同的早期生化途径,会造成组织损伤。本手稿还系统地汇编了 T2D 和帕金森病之间潜在的共同细胞机制,并讨论了将抗糖尿病药物作为帕金森病潜在治疗方案的文献。本综述涵盖了有关抗糖尿病药物治疗帕金森病的实验和临床疗效的研究,以及所提出的作用机制。探索抗糖尿病药物对帕金森病的益处为治疗这种神经退行性疾病提供了一条前景广阔的途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinical Parkinsonism  Related Disorders
Clinical Parkinsonism Related Disorders Medicine-Neurology (clinical)
CiteScore
2.70
自引率
0.00%
发文量
50
审稿时长
98 days
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