Gaziantep Islam Science and Technology University最新文献

GIANT BARTHOLIN CYST CASE REPORT 巨大巴托林囊肿1例报告

Gaziantep Islam Science and Technology University Pub Date : 2023-10-18 DOI: 10.46871/eams.1295539

Ferhat ASLAN, Kazım Ersin ALTINSOY

引用次数: 0

68Ga-DOTATATE PET/CT on the Follow-up of Patients with Medullary Thyroid Carcinoma 68Ga-DOTATATE PET/CT对甲状腺髓样癌患者随访的影响

Gaziantep Islam Science and Technology University Pub Date : 2023-10-18 DOI: 10.46871/eams.1364159

Ebuzer KALENDER, Vuslat ÇİMEN, Umut ELBOGA, Ufuk ÇİMEN, Zeki ÇELEN

引用次数: 0

Investigation of the effect of thymoquinone on kidney damage in isoproterenol-induced myocardial infarction in rats and cardiorenal interactions 百里醌对异丙肾上腺素所致大鼠心肌梗死肾损害及心肾相互作用的影响

Gaziantep Islam Science and Technology University Pub Date : 2023-10-03 DOI: 10.46871/eams.1359212

Ayşegül Burçin YILDIRIM, Necla DEĞER, Meryem SAYAN, Ali AKIN, Tayfun CEYLAN, Emin KAYMAK, Mehmet KARA, Murat ÜNSAL, Derya KARABULUT

{"title":"Investigation of the effect of thymoquinone on kidney damage in isoproterenol-induced myocardial infarction in rats and cardiorenal interactions","authors":"Ayşegül Burçin YILDIRIM, Necla DEĞER, Meryem SAYAN, Ali AKIN, Tayfun CEYLAN, Emin KAYMAK, Mehmet KARA, Murat ÜNSAL, Derya KARABULUT","doi":"10.46871/eams.1359212","DOIUrl":"https://doi.org/10.46871/eams.1359212","url":null,"abstract":"This study aimed to determine whether thymoquinone has any protective effects on renal tissue after an isoproterenol-induced myocardial infarction (MI). Experimental groups were formed as 4 groups (n=8). Control group (C). Thymoquinone group (THQ), 20 mg/kg single dose intragastric (i.g.) daily for seven days. Isoproterenol group (ISO) was administered 100 mg/kg intraperitoneally in two doses on days 7 and 8 of the experiment. Thymoquinone+Isoproterenol group (THQ+ISO), THQ 20 mg/kg i.g. was administered once a day for seven days. In addition, two doses of ISO 100 mg/kg i.p. were administered on the seventh and eighth days. Kidney tissues were evaluated histopathologically. Kidney tissues were evaluated histopathologically. Tumour necrosis factor alpha(TNF-α) and alpha Smooth Muscle Actin(α-SMA) immunoreactivity density changes were determined by immunohistochemistry. Glutathione(GST), Glutathione S-transferases(GSTs) and Interleukin-6(IL-6) levels were evaluated by ELISA method. Isoproterenol injection caused severe histopathological changes on kidney tissue. Also TNF-α and α-SMA levels were found to be higher in groups where ISO was administered. THQ could be effective on kidney tissue to partially correct these histopathological damages, by decreasing fibrosis and inflammation. This study shows that treatment with THQ is effective in preventing kidney damage caused by ISO-induced MI. We think that THQ as a supplementary food will be effective to prevent kidney damage.","PeriodicalId":335844,"journal":{"name":"Gaziantep Islam Science and Technology University","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135789692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the change in seroprevalence of viral hepatitis in patients receiving hemodialysis treatment over the years: A Single-Center Study 多年来接受血液透析治疗的患者病毒性肝炎血清患病率变化的调查:一项单中心研究

Gaziantep Islam Science and Technology University Pub Date : 2023-09-08 DOI: 10.46871/eams.1229510

Safiye KOÇULU DEMİR, Tülin AKAGÜN

{"title":"Investigation of the change in seroprevalence of viral hepatitis in patients receiving hemodialysis treatment over the years: A Single-Center Study","authors":"Safiye KOÇULU DEMİR, Tülin AKAGÜN","doi":"10.46871/eams.1229510","DOIUrl":"https://doi.org/10.46871/eams.1229510","url":null,"abstract":"Objective: In this study, it was aimed to evaluate HBV, HCV, and HIV seroprevalence and their 9-year changes in patients receiving hemodialysis (HD) treatment in the Giresun province in Turkey. Material-Methods: A total of 607 patients over the age of 18 who received hemodialysis treatment in Giresun – Turkey, provincial and district hospitals in 2013 and 2022 were included in our study. The files of the patients were reviewed retrospectively. Demographic characteristics of the patients and serology results of HBV, HCV, HDV, and HIV were recorded. The data was evaluated using the IBM SPSS Statistics 25.0 program. Results: A total of 607 patients, 385 of whom received HD treatment in 2013 and 222 who received HD treatment in 2022, were included in the study. 230 (59.7%) in 2013 and 135 (60.8%) in 2022 of male patients. While the mean age of the patients was 60.26±14 years in 2013, it was 63.08±13.18 years in 2022. In 2013, HBsAg positivity was detected in 9 (2.3%), HBV-DNA positivity in 4 (44.4%), anti-HCV positivity in 31 (8.1%), and HCV-RNA positivity in 8 (25.8%) patients. In 2022, HBsAg positivity was detected in 4 (1.8%), HBV DNA positivity in 2 (50%), and anti-HCV positivity in 31 (8.1%) patients. Compared with dialysis duration, the anti-HCV positivity rate was significantly increased in patients with long dialysis duration (p","PeriodicalId":335844,"journal":{"name":"Gaziantep Islam Science and Technology University","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136363069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Overview of The Various Appropriate Types of Cell Lines for The Production of Monoclonal Antibodies 用于生产单克隆抗体的各种合适类型的细胞系综述

Gaziantep Islam Science and Technology University Pub Date : 2023-06-07 DOI: 10.46871/eams.1254823

Shahin JAVANMARD

引用次数: 0

Investigation of Dynamic Thiol Disulfide Homeostasis in Acute Respiratory Failure Patients in Intensive Care Unit 重症监护病房急性呼吸衰竭患者动态硫代二硫体内平衡的研究

Gaziantep Islam Science and Technology University Pub Date : 2021-07-01 DOI: 10.46871/eams.2021.20

Zeynep Pınar Apaydın, H. Yıldız, Fatma Sinem Samim, B. Alaşehirli

{"title":"Investigation of Dynamic Thiol Disulfide Homeostasis in Acute Respiratory Failure Patients in Intensive Care Unit","authors":"Zeynep Pınar Apaydın, H. Yıldız, Fatma Sinem Samim, B. Alaşehirli","doi":"10.46871/eams.2021.20","DOIUrl":"https://doi.org/10.46871/eams.2021.20","url":null,"abstract":"Thiols are antioxidant agents which belong to mercaptan group consisting of sulfur and carbon containing sulfhydryl (-SH). Thiol levels, in the case of elevated oxidative stress, are lowered by their use in neutralization of reactive oxygen molecules. It was aimed to investigate thiol and disulfide blood levels or thiol/disulfide ratio as a marker of total oxidant status which plays a role in the pathogenesis of inflammatory diseases that may cause respiratory failure. The study included 98 patients (58 males, 40 females) who have partial oxygen pressure (PaO2)<60 mmHg or partial carbon dioxide pressure (PaCO2)>45 mmHg in arterial blood in intensive care unit and 98 healthy volunteers. Total thiol and native thiol levels were measured by spectrophotometric method. Total thiol (270 ± 99.81), native thiol (203.90 ± 103.41) and disulfide (33.10 ± 12.42) levels of the patient group were significantly lower (p <0.001) than total thiol (423.62 ± 70.3), native thiol (307.13 ± 57.73) and disulfide (58.24 ± 27.21) of the control group levels. There is no significant difference between native thiol / total thiol, disulfide / total thiol and disulfide / native thiol ratios. This study may be the first study in the literature in terms of providing the diagnosis and follow-up of dynamic thioldisulfide balance in patients with acute respiratory failure requiring intensive care support treatment. Thiol and disulfide blood levels or thiol / disulfide ratio can guide us as a prognostic test in acute respiratory failure patients.","PeriodicalId":335844,"journal":{"name":"Gaziantep Islam Science and Technology University","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122730177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fear of Coronavirus, Emotional Eating Behaviours, and Physical Activity Levels during the Coronavirus Pandemic in Individuals Over 65 Years of Age 65岁以上人群冠状病毒大流行期间对冠状病毒的恐惧、情绪化饮食行为和身体活动水平

Gaziantep Islam Science and Technology University Pub Date : 2021-07-01 DOI: 10.46871/eams.2021.19

Sabriye Ercan, Ahsen Oğul, Furkan Küçük, C. Çetin

{"title":"Fear of Coronavirus, Emotional Eating Behaviours, and Physical Activity Levels during the Coronavirus Pandemic in Individuals Over 65 Years of Age","authors":"Sabriye Ercan, Ahsen Oğul, Furkan Küçük, C. Çetin","doi":"10.46871/eams.2021.19","DOIUrl":"https://doi.org/10.46871/eams.2021.19","url":null,"abstract":"The Covid-19 pandemic has led to dramatic changes in lifestyle across populations. This study aimed to investigate the relationship between fear of Coronavirus, emotional eating behaviour and physical activity levels in individuals aged >65 years, and to determine the differences between individuals who did and did not gain weight during the pandemic. The study included individuals aged>65 years who were not diagnosed with Coronavirus disease (Covid-19). Participants’ demographic information, Fear of Covid-19 Scale scores, Emotional Eater Questionnaire (EEQ) scores, and physical activity levels according to the General Practice Physical Activity Questionnaire (GPPAQ) were recorded with an online questionnaire. The study included a total of 156 participants (72 females, 46.2%; 84 males, 53.8%). The average age was 71.86 ± 7.13 years. The average change in body mass index (BMI) between February 2020 and January 2021 was 0.80 ± 1.32 kg/m 2 . Participants were divided into two according to change in body mass index during the pandemic as weight-gain (WG, n=104) and non-weight-gain (NWG, n=52) groups. The two groups were not different in terms of descriptive characteristics, the Fear of Covid-19 Scale scores, and physical activity levels (p>0.05). The WG group scored statistically higher in EEQ, and the EEQ type-of-food subscale (p=0.027, p=0.029, respectively). Current BMI, overall EEQ score, and EEQ disinhibition and type-of-food subscores were weakly positively correlated with the change in BMI (p˂0.05). EEQ guilt subscores were weakly positively correlated with the age (p˂0.05). The change in BMI during the Covid-19 quarantine was associated with the EEQ overall score and its subscales among elderly adults. Physical activity levels of groups were similar and participants who gained weight were more prone to emotional eating.","PeriodicalId":335844,"journal":{"name":"Gaziantep Islam Science and Technology University","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128216026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systemic Inflammatory Index and Platelet-to-Lymphocyte Ratio Predict Mortality in Patients with Acute Myocardial Infarction 全身炎症指数和血小板与淋巴细胞比值预测急性心肌梗死患者的死亡率

Gaziantep Islam Science and Technology University Pub Date : 2021-07-01 DOI: 10.46871/eams.2021.18

S. Karahan, E. Okuyan

引用次数: 2

ABO Blood Groups and Hyperbaric Oxygen Therapy Effectiveness in Sudden Hearing Loss ABO血型与高压氧治疗突发性听力损失的疗效

Gaziantep Islam Science and Technology University Pub Date : 2021-06-29 DOI: 10.46871/eams.2021.21

E. Eren, Furkan Yıldırım, O. Giray, N. Yılmaz

{"title":"ABO Blood Groups and Hyperbaric Oxygen Therapy Effectiveness in Sudden Hearing Loss","authors":"E. Eren, Furkan Yıldırım, O. Giray, N. Yılmaz","doi":"10.46871/eams.2021.21","DOIUrl":"https://doi.org/10.46871/eams.2021.21","url":null,"abstract":"The efficiency of hyperbaric oxygen (HBO) treatment according to ABO blood group system was evaluated in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). Serum lipid values and novel atherogenic risk calculations of 346 patients who came to the clinic for HBO treatment were performed. HBO treatment efficiency was evaluated on ABO blood groups. The effect of serum lipid levels and atherogenic risk levels on HBO treatment was measured according to the blood groups of ISSNHL patients. The most important finding is that ISSNHL patients with O blood group antigen benefit the least from HBO therapy. Moreover, patients with O blood group antigen had statistically lower serum lipid values and atrogenic risk index than patients with non-O blood group. In addition, the frequency of O blood group in ISSNHL patients was higher than in non-O blood groups. The effect of serum lipid values and atherogenic risk indices in ISSNHL patients receiving HBO therapy may vary according to ABO blood groups. The relationship between hyperbaric oxygen therapy and the ABO blood grouping system should be supported by further research.","PeriodicalId":335844,"journal":{"name":"Gaziantep Islam Science and Technology University","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132687949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphometric Analysis of the Relationship between Bigonial Width and Cranium 双叉宽度与颅骨关系的形态计量学分析

Gaziantep Islam Science and Technology University Pub Date : 2021-03-29 DOI: 10.46871/eams.2021.14

S. S. Meyvaci, Mustafa Hızal

{"title":"Morphometric Analysis of the Relationship between Bigonial Width and Cranium","authors":"S. S. Meyvaci, Mustafa Hızal","doi":"10.46871/eams.2021.14","DOIUrl":"https://doi.org/10.46871/eams.2021.14","url":null,"abstract":"In the present study, the purpose was to determine the relation between bigonial width and craniometric parameters. This study, 7 craniometric parameters were examined based on computed tomography images of 110 adult individuals 58 of whom were males and 52 females. There parameters were Bigonial Width (BGW) in mandibula, and Maximum Cranium Width (MCW), Upper Face Width (UFW), Bizygomatic Width (BZW), Vertex-Prosthion Height (VPH), Vertex-Nasion Height (VNH), Upper Face Height (UFH) in cranium. The difference between two groups was examined with t-test in independent groups. The relation between numerical variables was examined with the Pearson Correlation Coefficient. The analyses were made with IBM SPSS v.21. Significance level was taken as p<0.05. When the morphometric relation between the mandibula and cranium was examined, it was found that although a relation was detected between BGW and all craniometric parameters, there was a relation between BGW and MCW, UFW, BZW in men, and UFW and BZW parameters in females when gender was taken into account (p<0.05). No significant correlations were detected between BGW and VPH, VNH, UFH measurement values in both genders. This study revealed that there is a significant relation between BGW and UFW and BZW parameters in both genders. It is considered that the relation between the mandibula and cranium can be used in the clinic when it should be considered, and the results will contribute to scientific studies.","PeriodicalId":335844,"journal":{"name":"Gaziantep Islam Science and Technology University","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114228174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0