ABO Blood Groups and Hyperbaric Oxygen Therapy Effectiveness in Sudden Hearing Loss

Abstract

The efficiency of hyperbaric oxygen (HBO) treatment according to ABO blood group system was evaluated in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). Serum lipid values and novel atherogenic risk calculations of 346 patients who came to the clinic for HBO treatment were performed. HBO treatment efficiency was evaluated on ABO blood groups. The effect of serum lipid levels and atherogenic risk levels on HBO treatment was measured according to the blood groups of ISSNHL patients. The most important finding is that ISSNHL patients with O blood group antigen benefit the least from HBO therapy. Moreover, patients with O blood group antigen had statistically lower serum lipid values and atrogenic risk index than patients with non-O blood group. In addition, the frequency of O blood group in ISSNHL patients was higher than in non-O blood groups. The effect of serum lipid values and atherogenic risk indices in ISSNHL patients receiving HBO therapy may vary according to ABO blood groups. The relationship between hyperbaric oxygen therapy and the ABO blood grouping system should be supported by further research.