International Journal Of Medical Science And Clinical Research Studies最新文献

{"title":"Scalp Spinal Cell Carcinoma Managed with Resection and Ying Yang Flap","authors":"Héctor Manuel Suárez Ortega, Juan Jesús Ortega Landeros, Jairo Isaih Mendoza Argáez, Francisco Alberto Montaño Vásquez del Mercado, Karina Lizbeth Lara Sampayo, Grecia Pavlova Salazar Gutiérrez, Irad Antonio Zuñiga Salazar, Gonzalo Santos González, Luis Adrián Guadarrama Mendoza, Jessica Valeria Parra Cárdenas, José David Rodríguez Enríquez, Diana Laura Páramo Hernández, Brenda Teresa López Mendoza","doi":"10.47191/ijmscrs/v4-i05-03","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i05-03","url":null,"abstract":"The second most frequent type of non-melanoma skin cancer is cutaneous squamous cell carcinoma (cSCC). We present the case of a squamous cell carcinoma of the scalp with surgical management and the importance of the Ying-yang flap. Ying-Yang flaps\" are employed when there is stress on the incision, especially on the scalp and lower extremities.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"110 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141002693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Infarct of Myocardium without Coronary Arterial Obstructive Disease in a Patient with Colon Cancer: A Case Report","authors":"Ramírez- Juárez, Nateras- Quiroz, Alondra, Martínez- Maldonado, Fernando, Reyes-Ramírez, Javier, Elizabeth Armijo Yescas, Tania Hernández Trejo, Carlos Augusto Contreras Martinez","doi":"10.47191/ijmscrs/v4-i05-04","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i05-04","url":null,"abstract":"We report a 40-year-old female with colon cancer, in its first session of treatment with capecitabine/oxaliplatin, who presented an event of acute coronary syndrome type myocardial acute infarction with ST inferior elevation in the first 30 days after initiation of adjuvant treatment, angiographically without lesions and echocardiographically presented impaired ventricular function. This case report illustrates myocardial damage induced by antimetabolites in an acute manner.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141007268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological and Nonpharmacological Interventions for Prevention and Management of Pulmonary Embolism in Patients with Cardiac Comorbidities: A Literature Review","authors":"Dennys Paul Guaraca Huilcarema, Juan Carlos Yánez Tobar, Robinson David Moya Pilay, Shirly Andrea Pagalo Tacuri, Galo Fernando Tulcanaza Ochoa, Mishelle Estefania Garcés López, Melany Dayana Albán Galarza","doi":"10.47191/ijmscrs/v4-i05-02","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i05-02","url":null,"abstract":"Pulmonary embolism (PE) presents significant healthcare challenges and potentially life-threatening consequences, demanding a nuanced approach to management. This systematic review aimed to critically evaluate available pharmacological and nonpharmacological interventions for PE, analyzing their efficacy and safety in patients with cardiac comorbiditie, ranging from traditional anticoagulants like warfarin to novel direct oral anticoagulants (DOACs) or thrombolytic therapies is commercially available options with varying benefits and limitations. Nonpharmacological interventions, including catheter-directed therapies and embolectomy, provide alternative avenues, especially when thrombolysis is contraindicated despite advancements, and gaps persist, particularly in reconciling efficacy with safety profiles and optimizing resource allocation. Addressing these challenges necessitates a multidisciplinary approach, integrating clinical expertise with evidence-based practices. By exploring these interventions' intricacies and implications, this review aims to inform clinicians, researchers, and policymakers, fostering improved care pathways and better outcomes for patients facing the complex landscape of PE management.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"42 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141014021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the Relationship between Quality of Life and Baseline Hemoglobin Level in Lung Cancer with Chemotherapy Treatment Using EORTC QLQ-LC13","authors":"Adelin Kole, Suryanti Dwi Pratiwi, Ngakan Putu Parsama Putra, U. Setyawan, Deden Permana","doi":"10.47191/ijmscrs/v4-i05-01","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i05-01","url":null,"abstract":"Background: The effect of lung cancer and its various treatments on the overall well-being can be substantial. This study seeks to examine the correlation between quality of life and baseline hemoglobin (Hb) levels in lung cancer patients who are receiving chemotherapy. Method: This study involved 30 patients with non-small cell lung cancer (NSCLC) who underwent platinum-based chemotherapy. Baseline Hb level were collected from medical records. The patients' quality of life was assessed using interviews utilizing the EORTC QLQ-LC13 questionnaire. Result: Baseline Hb levels and pain relief after medication score was positively correlated (r=0.559, p=0.001). Baseline Hb levels and difficulty swallowing score was negatively correlated (r=-0.386, p=0.035). Determined cut-off point for the total score was 303.5. However, the correlation between Hb levels and overall quality of life was insignificant (r=-0.096, p=0.615). Conclusion: According to the quality of life indicators in the questionnaire, there is a notable association between lower baseline Hb levels and reduced effectiveness of pain relief medication, as well as an increase in difficulty swallowing. However, the underlying cause for this correlation is unclear. On the other hand, the correlation between baseline Hb levels and the overall scores of quality of life in the questionnaire was not found to be significant.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"122 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141015290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Central Nervous System Relapse in Diffuse Large B-Cell Lymphoma: A Comprehensive Review","authors":"Isai Gallegos Gomez, Melissa Anahí Chan Verdugo, Jennifer Aída Ortega Romero, Daniela Denisse Torreros Lara, Rodrigo García González, Carmen Sabrina Campaña Medina, Ariadna Padilla, Abel Gallegos Aguilar, Eotoniel Sanchez Romero","doi":"10.47191/ijmscrs/v4-i03-31","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-31","url":null,"abstract":"Central nervous system (CNS) relapse in diffuse large B-cell lymphoma (DLBCL) is a rare but serious complication associated with poor outcomes. The prevalence of CNS relapse in DLBCL varies widely in the literature, ranging from 1% to 30%, depending on several risk factors and diagnostic methods. This article provides a comprehensive review of the current literature on the prevalence of CNS relapse in DLBCL, focusing on risk factors, diagnostic approaches, and treatment strategies. Understanding the epidemiology and clinical characteristics of CNS relapse in DLBCL is crucial for the development of effective preventive and therapeutic strategies.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"61 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding The Role of SGLT2 Inhibitors in Cardiovascular Risk Reduction for Type 2 Diabetes Patients-A Literature Review","authors":"Jorge Eduardo Arteaga Molina, Ney Asdrubal Macias Valdez, Diego Alberto Vargas Corredor, José Manuel Vera Cruzatty, Annabel Fernández Alfonso, Boris Alexander Zapata Luzardo, Ana Paula Coronel Mite, Viviana Eloisa Muñoz Calle","doi":"10.47191/ijmscrs/v4-i03-29","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-29","url":null,"abstract":"Introduction: Type 2 diabetes mellitus (T2DM) is associated with an increased risk of cardiovascular events and heart failure. Sodium-glucose cotransporter 2 (SGLT2) inhibitors have emerged as a novel class of antidiabetic agents with potential cardiovascular benefits. This systematic review aims to evaluate the impact of SGLT2 inhibitors on reducing cardiovascular events and heart failure hospitalizations in patients with T2DM. Aims: The review aims to comprehensively evaluate the impact of SGLT2 inhibitors on reducing cardiovascular events, including MACE, and HF hospitalizations in patients with T2DM. Methods: A comprehensive literature search was conducted in major electronic databases like PubMed, Google Scholar and Science Direct to identify relevant studies. Studies investigating the cardiovascular outcomes of SGLT2 inhibitors in T2DM patients were included. Data extraction and quality assessment were performed independently by three reviewers using predefined criteria. Results: A total of 17 studies met the inclusion criteria and were included in the review. The analysis of clinical trials, including EMPA-REG OUTCOME, CANVAS Program, and DECLARE-TIMI 58, demonstrated significant reductions in MACE and HF hospitalizations with SGLT2 inhibitors compared to placebo or standard care. Real-world evidence from studies such as the CVD-REAL and EASEL studies further supported these findings, showing consistent cardiovascular benefits of SGLT2 inhibitors in routine clinical practice. The findings suggest that SGLT2 inhibitors are associated with a reduction in cardiovascular events, including myocardial infarction, stroke, and cardiovascular mortality, as well as a decreased risk of heart failure hospitalizations in patients with T2DM. Conclusion: This systematic review provides evidence supporting the cardiovascular benefits of SGLT2 inhibitors in T2DM management. The findings underscore the importance of considering these agents as part of comprehensive cardiovascular risk reduction strategies in T2DM patients. Further research is necessary to explicate the mechanisms underlying these benefits and optimize their clinical use.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"20 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140368197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updates in Nasal Reconstructive Surgery","authors":"José Fernando Montiel Castañeda, Oscar Gregorio Gonzalez Cambero, Alexis Andrei Granados Flores, Rodrigo Rueda De León Serna, Aldair Cruz Gallardo, Alhan Fernando Castillo Valencia, Griselda Luna Quizihuitl, Francisco Javier Mijangos Delgado, Massiel Alfonsina Ávila Ramírez, Verónica Gonzalez Mascareño","doi":"10.47191/ijmscrs/v4-i03-30","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-30","url":null,"abstract":"The primary cause of rhinoplasty's difficulty is the fact that every move made during the procedure has both planned and unforeseen consequences. This report's objective is to examine the research and provide an update on rhinoplasty dynamics. Surgeons doing rhinoplasty operations need to keep reevaluating the dynamics of different movements as the procedure's procedures advance.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"92 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140370858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Halitosis in Elderly (A Pilot Study in Tresna Werdha Melania Nursing Home)","authors":"Poetry Oktanauli, Pinka Taher, Margaretha Herawati, Herlia Nur Istindiah, Ratih Widyastuti, Rini Triani, Ika Anisyah, Ali Zainal Abidin","doi":"10.47191/ijmscrs/v4-i03-28","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-28","url":null,"abstract":"BACKGROUND: Elderly is a person who has reached the age of more than 60 years old. Elderly generally experiences a decreased in oral hygiene, number of teeth, mucosal sensitivity of the oral cavity and xerostomia. Xerostomia can cause the decreased in oral hygiene and cause an increase in bad breath (halitosis). OBJECTIVES: The purpose of this study is to provide information about halitosis score in elderly. METHODS: This was descriptive research with cross sectional approach. The numbers of subject were 30 and obtained by quota sampling. Data collection was done by anamnesis and by measuring halitosis score, using Tanita breath checker. Tanita breath checker is an innovative palm-sized monitor that able to detect and measure the presence of volatile sulfur compound (VSC) by displaying the level of halitosis. RESULTS: Distribution of halitosis frequency in elderly based on gender were more female than male. Distribution of halitosis frequency in elderly based on halitosis score showed that there were fourteen subjects with a halimeter score of 2 while other scores were less than fourteen subjects. Halitosis frequency distribution based on anamnesis, subjects who had bad breath complaints were more than those who did not have bad breath. Conclusions: Based on the results, it can be concluded that halitosis in elderly were caused by many factors, such as dental caries and the habit of the subject who liked to eat smelly foods.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"15 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140373127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Approaches in the Management of Monoclonal Gammopathies: an approach to Waldenström Macroglobulinemia","authors":"Isai Gallegos Gomez, Jennifer Aída Ortega Romero, Daniela Denisse Torreros Lara, Rodrigo García González, Carmen Sabrina Campaña Medina, Ariadna Padilla, Abel Gallegos Aguilar, Eotoniel Sanchez Romero","doi":"10.47191/ijmscrs/v4-i03-01","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i03-01","url":null,"abstract":"Monoclonal gammopathies encompass a spectrum of disorders characterized by the abnormal proliferation of plasma cells, leading to the production of monoclonal immunoglobulins. Waldenström macroglobulinemia (WM) is a rare, indolent lymphoproliferative disorder characterized by the presence of an IgM monoclonal gammopathy, bone marrow infiltration by lymphoplasmacytic cells, and clinical features such as hyperviscosity, lymphadenopathy, and hepatosplenomegaly. Recent advances in understanding the pathogenesis of WM have led to the development of novel therapeutic strategies, including targeted therapies and immunomodulatory agents, which have significantly improved outcomes for patients. This article provides an overview of the current understanding of WM pathophysiology, clinical presentation, diagnostic approach, and recent advancements in its management.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140081899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumocephalus after ankle surgery: A Case Report","authors":"Carlos Antonio Torres Luna, Perla Alejandra Avilés-Sánchez, Víctor Arturo Montero-Solano","doi":"10.47191/ijmscrs/v4-i02-35","DOIUrl":"https://doi.org/10.47191/ijmscrs/v4-i02-35","url":null,"abstract":"Introduction: Pneumocephalus, or air in the cranial cavity, can have various causes. Traumatic brain injury is the most common cause of pneumocephalus, accounting for 75% of all cases, particularly in those with skull base fractures. Spinal trauma-related pneumocephalus is rare but has been reported, and patients with this condition are usually treated conservatively. Tumors, infections, and iatrogenic causes are responsible for the remaining 25% of cases. Proper management and a high index of suspicion are critical when considering pneumocephalus as a possible complication, as it can result in significant morbidity and potentially life-threatening consequences. Accidental puncture of the dura mater is a common cause of pneumocephalus secondary to epidural anesthesia, and air entry into the intrathecal space is another known cause. Case presentation: This is a 64-year-old female patient who underwent elective ankle surgery, the anesthetic technique was epidural-spinal block needle on needle, no complications during procedure. She was discharged from the Traumatology and Orthopedics service the next morning, 24 hours after her hospital discharge, she was brought back, in the emergency area, she was found with psychomotor agitation, disorientation, no auditory hallucinations, paresthesias were denied, no mentation disorder, with a score on the Glasgow Coma Scale of 14: Eye opening 4 points, Verbal response 4 points, Motor response 6 points. After 48 hours the CT brain scan revealed absortion of pneumocephalus. Clinical discussion: The causes of neumocephalus resulting from epidural or spinal anesthesia procedures are not entirely understood. However, it is believed to occur due to the introduction of air or gas into the subarachnoid or epidural spaces during the puncture, accidental or not . Given the potential severity of this condition, early diagnosis and appropriate management are crucial, even if the symptoms differ from the most common. Conclusion: This research paper highlights the importance of anesthesiologists being aware of the potential risks associated with epidural or spinal block. Future research could investigate the long-term outcomes of patients who experience pneumocephalus during anesthesia procedures and identify strategies for preventing and managing this complication.","PeriodicalId":335261,"journal":{"name":"International Journal Of Medical Science And Clinical Research Studies","volume":"13 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140412059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}