dnshnmh Srm最新文献

{"title":"Evaluation of the effects of the first stage of home quarantine for one week during the Covid 19 pandemic in Tehran province, Iran","authors":"M. Nejat, Habib Reshadi","doi":"10.52547/sjrm.5.2.54","DOIUrl":"https://doi.org/10.52547/sjrm.5.2.54","url":null,"abstract":"Commentary: In late 2019, a respiratory illness caused by the Corona virus was identified as the cause of several cases of pneumonia in Wuhan, China. Coronavirus (COVID-19), declared by the World Health Organization (WHO), is responsible for hundreds of thousands of medical records worldwide [1] . This disease has put a lot of costs on the health care system of countries around the world. Although scientists are increasingly monitoring the disease, a look at the diary statistics of the disease in Iran also shows that despite the measures taken, the disease has not yet been managed and controlled, and the statistics are increasing, if What successes have been achieved in the discussion of treatment and prevention of this disease. In the early stages of the disease, most countries used quarantine [2] and this quarantine was also implemented in Iran. The aim of this study was to look at the effects of the first stage of home quarantine for a week during the Covid 19 pandemic in Tehran. people a A in this study. Table shows the demographic and psychosocial characteristics of quarantine. The study questionnaire was distributed using an electronic link This questionnaire was distributed through social media for one week in Tehran province from 2020 April 8. The questionnaire included a form related to demographic characteristics and a form related to psychological indicators related to quarantine and coronation.","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49398912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the mannitol and albumin in management of the severe ovarian hyperstimulation syndrome (OHSS), a randomized clinical trial, with cost-effectiveness analysis","authors":"A. Saremi, Maryam Mahmodi Nia, Leila Zand Azad, Mohammad Reza Nateghi (MD, MPH), Maryam Sanaye Naderi","doi":"10.52547/sjrm.5.2.86","DOIUrl":"https://doi.org/10.52547/sjrm.5.2.86","url":null,"abstract":"Background: Ovarian hyperstimulation syndrome (OHSS) is potentially life-threatening complication including pleural effusion, acute renal insufficiency, and venous thromboembolism associated with controlled ovarian stimulation during assisted reproductive technology. A number of clinical studies have reported on the use of plasma expanders such as albumin, hydroxyethyl starch (HES), mannitol, polygeline and dextran as a possible intervention for the prevention of OHSS. Objective: The purpose of this study was to compare the efficacy and cost-effectiveness of mannitol rather than albumin for the treatment of severe OHSS. Materials and Methods: We conducted a single-center and comparative randomized clinical trial with two parallel patient groups. 47 patients with severe OHSS were selected with inclusion criteria. In albumin group (n=26), patients received 100 g/day intravenous albumin. Mannitol therapy (n=21) started twice a day using 100 gr mannitol infusion over 4 hours. Patients were monitored according to the standard protocol. Statistical analysis will be performed to analyze and compare the data between two groups in order to determine the efficacy (based on vital sign, abdominal circumference, weight, intake/output of fluid, correction of hemoconcentration), side effects and cost of drug therapy between the two treatment modalities. Results: The efficacy of drug therapy was evaluated by examining the results of daily urine output, serum biochemistry analytes, weight and abdominal circumference in both group. There were no significant differences between the two study groups in terms of patient age, clinical signs and symptoms, and laboratory findings such as hematocrit, creatinine, oliguria, weight, and abdominal size. Significant improvement of OHSS syndrome was observed in patients using mannitol which no patient was reported any side effects such as respiratory distress syndrome, renal failure, or thromboembolism. In the albumin group, 15.38 % of patients presented with acute respiratory distress syndrome (ARDS). Another outcome of this study was the significant economic difference between the two managements of severe ovarian hyperstimulation syndrome. Mannitol therapy was obviously cost-effective versus albumin therapy. Conclusion: The use of mannitol is comparable and superior to albumin for the treatment of severe OHSS with regard to the protective effect against the occurrence of acute respiratory distress syndrome. Base on this study, its cost-effectiveness makes mannitol an ideal drug for OHSS treatment. This study suggests that mannitol can be first-line therapy for the treatment of severe OHSS, therefore, the addition of mannitol as a treatment of ovarian hyperstimulation syndrome is recommended in the pharmacopeia.","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47427534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective effect of zinc oxide nanoparticles on sperm parameters after freezing","authors":"Elnaz Ashtari, F. Siadat, Niloofar Sodeifi, Sajjad Atashparvar","doi":"10.52547/sjrm.5.1.10","DOIUrl":"https://doi.org/10.52547/sjrm.5.1.10","url":null,"abstract":"Aims: Sperm freezing is most usable of method for the protection of reproductive performance in men who undergo gonadotoxic therapy such as chemotherapy or radiation treatment, or for the treatment of diseases such as infertility, autoimmune diseases and/or diabetes. Zinc oxide (ZnO) nanoparticle has potent anticancer and antioxidant effects. The purpose of this study was to evaluate the protective effects of various concentrations of this nanoparticle on sperm freezing. Methods: sixteen semen samples of normal human referred to Royan Center, were evaluated in 8 Fresh and Freeze and control groups. Groups included: Three fresh experimental groups were only exposed to ZnO nanoparticle with concentrations of 40, 80 and 100 ppm and were analyzed half an hour later. Three freezing experimental groups were frozen after included concentrations of ZnO nanoparticle and thawed and analyzed half an hour later. Two control groups including control 1: were analyzed half an hour after exposure in culture and control 2: half an hour after freezing were thawed and analyzed. Count, morphology, motility, viability and PH of sperm were evaluated. Findings: The results showed that 100 ppm concentration of ZnO nanoparticle had the best protective effect on sperm pH, survival, and motility in freezing process. Conclusion: ZnO nanoparticle at a concentration of 100 ppm can maintain pH, motility and survival of sperm in the freezing process.","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43932108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The evaluation of retinoic acid and estrogen on mouse induced pluripotent stem cells differentiation into female germ cells","authors":"J. Mahabadi, H. Nikzad, Hassan Hassani Bafrani, Z. Karami, Vajihe Taghdiri Nooshabadi","doi":"10.52547/sjrm.5.1.18","DOIUrl":"https://doi.org/10.52547/sjrm.5.1.18","url":null,"abstract":"Authors Aims: The use of stem cells has been able to treat patients with genetic and induced abnormalities and diseases such as non-obstructive azoospermia. Today, more attention has been paid to self-induced induced pluripotent stem cells (iPSCs). The aim of this study was to investigate the role of estrogen with retinoic acid on the differentiation of mouse iPSCs towards female germ cells. Methods: In this study, mouse embryonic fibroblast cells were extracted as feeding cells and inactivated. The target groups were adjusted for estrogen with retinoic acid at intervals of days 0, 4 and 7. Expression of these genes was performed by Real Time PCR technique. Results: In this study, the expression of genes such as Stra8, Stella, Ddx4 and GDF9 was evaluated. Real-time data showed that the expression of these genes increased in estrogen group on day 4 of embryoid bodies culture, while the differences were not significant on other days. Conclusion: It is very difficult to control the differentiation of mouse induced pluripotent stem cells (miPSCs) and the role of estrogen was carefully investigated in vitro in this study. Evidence suggests that female germ cells can differentiate from miPSCs in vitro. Treatment of cells with estrogen showed a greater effect on the differentiation process on day 4.","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48600825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of prevalence of symptoms, clinical and paraclinical finding in ultrasound and fertility outcomes in patients with PCO","authors":"Farahnaz Zandi","doi":"10.52547/sjrm.5.3.126","DOIUrl":"https://doi.org/10.52547/sjrm.5.3.126","url":null,"abstract":"","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46905416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non Invasive Prenatal Testing, Turning Point in Detection of Down and Other Frequent Trisomies","authors":"S. Taghizadeh, Tamouchin Moharrami, A. Mohammadpour, Golnoosh Goljah Rad, Leila Javanparast Sheikhani","doi":"10.52547/sjrm.5.3.113","DOIUrl":"https://doi.org/10.52547/sjrm.5.3.113","url":null,"abstract":"1 Sarem Fertility & Infertility Research Center (SAFIR) & Sarem Cell Research Center (SCRC), Sarem Women’s Hospital, Iran University of Medical Science (IUMS), Tehran, Iran. Background and Aims: Noninvasive prenatal genetic testing (NIPT), which analyzes cell-free fetal DNA circulating in maternal blood, is a new option in the prenatal screening and testing paradigm for trisomy 21 and a few other fetal chromosomal aneuploidies. NIPT technologies have been validated in singleton pregnancies at high risk for trisomy 21 due to advanced maternal age, an abnormal serum screen, personal or family history of aneuploidy, and abnormal ultrasound. The testing is non-invasive, so the pregnancy is not put at risk for miscarriage or other adverse outcomes associated with invasive testing procedures. At least 99% of all pregnancies with trisomy 21 can be detected using this test. However, up to 1 in 100 pregnancies with trisomy 21 will have a normal result and be missed on screening. Conclusion: The International Society of Prenatal Diagnosis (ISPD) and the Iranian Ministry of Health endorse the NIPT method as a suitable screening test for women at high risk for trisomy 21. Positive results should be confirmed by invasive tests. Future advances in NIPT technology promise to expand the range of conditions that can be detected, including single-gene disorders.","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44529758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High uterine artery pressure: a case report","authors":"S. Giti","doi":"10.52547/sjrm.5.3.108","DOIUrl":"https://doi.org/10.52547/sjrm.5.3.108","url":null,"abstract":"Introduction: The blood flow of the maternal uterine artery is an important factor that helps maintain the intrauterine environment and enables the normal placental function to support fetal growth and development. Preeclampsia is one of the leading causes of maternal and fetal mortality worldwide. The relationship between uterine artery blood flow and placental development is essential to understanding placental and its abnormalities in both preeclampsia and fetal growth restriction. This study aimed to report high uterine artery pressure as a case report . Case report: In this case, a 27-year-old woman, G 2 P 1 A 0 and 15 weeks referred to this center for pregnancy care. The patient had a history of normal and non-specific pregnancy in the first pregnancy. The second pregnancy was done normally and was not report any bleeding and or spotting. In first level screening, NT was increased and aspirin was administered due to resistance increasing in both uterine arteries. At 35 weeks and 4 days, the patient was hospitalized due to a severe increase in blood pressure, and the cesarean section was done with the final detection of preeclampsia. Finally, the patient was discharged with the good general condition and normal hypertension. Conclusion: High blood pressure is always a threatening factor in pregnancy and the lack of danger signs is not defining reason for the absence of this complication. Early detection and proper administration of preeclampsia can improve maternal and neonatal outcomes.","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44219378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General health in infertile women with polycystic ovary syndrome under infertility treatment referred to Sarem hospital","authors":"Fariba Mohammad Alayha, Mahtab Motie, L. Amini, Hamid Haghani3, Homa Sadeghi Avval Shahr","doi":"10.52547/sjrm.5.3.120","DOIUrl":"https://doi.org/10.52547/sjrm.5.3.120","url":null,"abstract":"cross-sectional The results of this study demonstrated that the mean age of subjects was 29.82±3.04 years and marriage duration was 12.98±2.99 years and these patients had a history of 9.98±2.98 years of infertility averagely. Most of these people had primary infertility (93.7%) and others patients had secondary infertility Also, in terms of general health, 43.7% of participants in this study had a mild disorder. The percentage of mild disorders in general health included 60.9% of physical symptoms, 37.6% of those with anxiety and sleep disorders, and 51.5% of social functions, while 68.8% had severe depression. But, none of these participants in the research had an intense disorder in the areas of social function. Conclusion: It can be concluded from this study that most infertile people under treatment had a severe disturbance in the depression; therefore, it seems that screening strategies and depression treatment should be noticed in their infertility course.","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48408351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The protective effect of alcoholic extract of Allium cepa seeds on the histopathological changes of epididymis in streptozotocine-induced diabetic rats","authors":"Mehran Kamani, H. Nikzad, M. Khodadadi","doi":"10.52547/sjrm.5.3.134","DOIUrl":"https://doi.org/10.52547/sjrm.5.3.134","url":null,"abstract":"Aims: Diabetes has adverse effect on male reproductive system. The onion ( Allium cepa ) seed is a rich natural source of antioxidant which can improve the damaging effects caused by diabetes on different tissues. The aim of this study was to examine the effect of alcoholic extract of onion seeds on the histopathological changes of epididymis in streptozotocine-induced diabetic rats. Methods: In this experimental study, 50 adult male Wistar rats were allocated into 5 groups (n=10). Groups 1 and 2 received 0.1 CC ethanol extract of onion seed in dosages of 200 and 400 mg/ kg body weight (B.W.) by stomach gavage daily. Group 3 (as control group) included healthy rats that received normal water and food for 4 weeks. Group 4 included untreated diabetic rats that received an intraperitoneal injection of STZ 60 mg/kg B.W. and with FBS>250 mg/ dose 3U/100 g B.W. by subcutaneous injection. Histological and morphological structures of the epididymis was evaluated in different groups. Findings: Our data showed that the histology parameters in diabetic rats receiving the extract was improved significantly. Administration of both doses of 200 and 400 mg/kg B.W. onion seed extract could increase epithelium height and decrease fibromuscular thickness significantly. Also, data demonstrated that tubule and lumen diameter did not change significantly in onion extract-treated groups. Conclusion: Our finding indicated that onion seed extract may be useful as a supplementary protective agent against adverse effects of diabetes on reproductive system in diabetic men.","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45406840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report of Cardio-Respiratory Arrest Suspected of Amniotic Fluid Embolism (Anaphylactoid Syndrome of Pregnancy)","authors":"Mojtaba Mir Aboutalebi, Mohamad Amin Samet, J. amini mahabadi, Mohammad Reza Nateghi (MD, MPH)","doi":"10.52547/sjrm.5.3.148","DOIUrl":"https://doi.org/10.52547/sjrm.5.3.148","url":null,"abstract":"will be associated with increased survival and reduced morbidity and mortality.","PeriodicalId":33200,"journal":{"name":"dnshnmh Srm","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41418601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}